Lauren

Interview Transcript Lynde (mother):
"She's had respiratory problems all her life. She used to miss like 30 to 40 days of school a year."

Lauren:
"I was born early, so I had a lot of respiratory problems. And when I got older, I had a lot of trouble breathing."

Lynde (mother):
"Lauren was first diagnosed with asthma when she was about six."

(We) tried all different kinds of medications. At one point, she was on 11 different meds every day. We weren't having a lot of luck with them."

Lauren:
"My doctor recommended Xolair® (Omalizumab) to us. I've been on Xolair for about three and half years."

Lynde (mother):
"She gets her shots every two weeks, and it's doing well for her. She is so active now and into so many things. She's changed so much."

Lauren:
"When I started volleyball, I wasn't on Xolair, so it was harder. And as I started using it, it got better, so now I don't have to use my inhaler as much."

Product Indication: Xolair is a prescription medicine given by injection for people who are 12 years of age and above who have moderate-to-severe persistent asthma that is triggered by year-round allergens in the air. A simple skin or blood test will confirm that you have this kind of asthma. This is known as allergic asthma. Xolair helps reduce the number of asthma attacks in people with allergic asthma who still have asthma symptoms even though they are taking inhaled steroids. Xolair has not been proven to work in other allergic conditions.

Important Safety Information: Xolair should always be injected in a doctor's office. You should read the Medication Guide before starting Xolair treatment and before each and every treatment.

A severe allergic reaction called anaphylaxis has happened in some patients after they received Xolair. Anaphylaxis is a life-threatening condition. Seek emergency medical treatment right away if symptoms occur. Signs and symptoms of anaphylaxis include:

• wheezing, shortness of breath, cough, chest tightness, or trouble breathing
• low blood pressure, dizziness, fainting, rapid or weak heartbeat, anxiety, or feeling of "impending doom"
• flushing, itching, hives, or feeling warm
• swelling of the throat or tongue, throat tightness, hoarse voice, or trouble swallowing You should not receive Xolair if you have ever had an allergic reaction to a Xolair injection. Do not use Xolair if you are allergic to any of its ingredients.

In clinical studies 0.5 % of patients receiving Xolair developed cancer, compared to 0.2% of patients receiving placebo injections.

In clinical studies, the most common side effects in patients receiving Xolair included injection-site reactions (45%), viral infections (23%), upper respiratory tract infection (20%), sinus infection (16%), headache (15%), and sore throat (11%).

Do not change or stop taking any of your other asthma medicines unless your doctor tells you to do so. You may not see an immediate improvement in your asthma when beginning Xolair therapy.

Talk to your doctor for more information and if you have any questions about your treatment.

Please see the full Prescribing Information including Boxed WARNING and Medication Guide for additional safety information.

Individual results may vary.