Amita Joshi
VP Clinical Pharmacology, Development Sciences
"Patient Focused, Data Driven"
24
Years at Genentech
45
Publications at Genentech
4
Awards & Honors
I joined Genentech in 2000 as a Senior Scientist specialized in Clinical Pharmacokinetics and over the years have held various team and leadership roles leading to my current position as Vice President of Clinical Pharmacology. I have had the opportunity to see my individual impact on a number of biologics and small molecules and feel fortunate to work with such a talented and diverse group of passionate colleagues at Genentech.
In my role as head of Clinical Pharmacology, I am responsible for ensuring that the right dose and dosing regimen is identified for the successful approval of our medicine. We have done this by applying the principles of quantitative pharmacology to understand the pharmacokinetics of our medicines and better define drug exposure and response (safety/efficacy/ pharmacodynamics) relationships, determining appropriate dose/regimen for patients and dose adjustments for special populations (eg, pediatrics, elderly, organ impairment, ethnicity etc).
My Focus
As the industry pivots to use new ways to integrate data into decision-making to enable availability of breakthrough medicines to patients and to improve productivity in Pharma R&D, I have focused my energy to identify what a best imaginable Clinical Pharmacology group would deliver in this new world of the future. This has led to the new and compelling Vision for Clinical Pharmacology "We will design novel clinical trials, replace clinical trials by virtual modeling, and pioneer analytics at point-of-care in order to provide personalized patient-centric treatment to meet the evolving healthcare needs of tomorrow and beyond.”
Genentech Publications
British Journal of Clinical Pharmacology, ISSN: 03065251
Rui Zhu; Rik Schoemaker; Aurelie Gautier; Xianbin Tian; Cheryl HooiMing Sim; Theodore A. Omachi; Amita Joshi; Jin Jin; Ryan Owen
Clinical Pharmacology and Therapeutics, ISSN: 00099236
Amita Joshi
European Journal of Pharmaceutical Sciences, ISSN: 18790720 09280987
Amita Joshi; Ramanujan; Jin Y. Jin
Clinical and Translational Science, ISSN: 17528062 17528054
Benjamin Wu; Nitzan Sternheim; Priya Agarwal; Julia Suchomel; Shweta Vadhavkar; Rene Bruno; Ballinger; Coen A. Bernaards; Phyllis Chan; Jane Ruppel; Jin Jin; Sandhya Girish; Amita Joshi; Quarmby
British Journal of Clinical Pharmacology, ISSN: 13652125 03065251
Sonoko Kawakatsu; Rene Bruno; Kagedal; Chunze Li; Sandhya Girish; Amita Joshi; Benjamin Wu
Clinical Cancer Research, ISSN: 15573265 10780432
Laurent Claret; Jin Y. Jin; Charles Ferte; Helen Winter; Sandhya Girish; Mark Stroh; Pei He; Ballinger; Alan Sandler; Amita Joshi; Achim Rittmeyer; David R. Gandara; Jean-Charles Soria; Rene Bruno
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Chunze Li; Wang; Shang-Chiung Chen; Russell D. Wada; Dan Lu; Xin Wang; Daniel Polhamus; Jonathan French; Shweta Vadhavkar; Alexander Strasak; Melanie Smitt; Amita Joshi; Meghna Samant; Angelica Quartino; Jin Y. Jin; Sandhya Girish
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Dan Lu; Leonid Gibiansky; Priya Agarwal; Randall Dere; Chunze Li; Yu-Waye Chu; Jamie Hirata; Amita Joshi; Jin Y. Jin; Sandhya Girish
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Kelong Han; Laurent Claret; Piao; Priti Hegde; Amita Joshi; Powell; Jin Y. Jin; Rene Bruno
Pharmaceutical Biotechnology: Fundamentals and Applications, Third Edition,
Banmeet S. Anand; Rong Deng; Frank-Peter Theil; Jing Li; Shasha Jumbe; Thomas R. Gelzleichter; Fielder; Amita Joshi; Sara Kenkare-Mitra
Cancer Chemotherapy and Pharmacology, ISSN: 14320843 03445704
Dan Lu; Tong Lu; Mark Stroh; Richard A. Graham; Priya Agarwal; Luna Musib; Chi-Chung Li; Bert L. Lum; Amita Joshi
Journal of Clinical Pharmacology, ISSN: 15524604 00912700
Yi Zhang; Xiaohui Wei; Gaurav Bajaj; Jeffrey S. Barrett; Bernd Meibohm; Amita Joshi; Manish Gupta
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Dan Lu; Amita Joshi; Li; Nancy Zhang; Melanie Ren; Yuying Gao; Russell D. Wada; Jin Y. Jin
Journal of Clinical Pharmacology, ISSN: 15524604 00912700
Laurent Claret; Manish Gupta; Kelong Han; Amita Joshi; Nenad Sarapa; Jing He; Bob Powell; Rene Bruno
Journal of Clinical Pharmacology, ISSN: 00912700 15524604
Yan Xin; Denise Jin; Stephen M. Eppler; Lisa A. Damico; Amita Joshi; John Davis; Surinder Kaur; Ihsan Nijem; John Bothos; Amy Peterson; Premal Patel; Shuang Bai
Clinical Pharmacokinetics, ISSN: 03125963 11791926
Dan Lu; Amita Joshi; Wang; Steve Olsen; Joo-Hee Yi; Ian E. Krop; Howard A. Burris; Sandhya Girish
Clinical Pharmacology and Therapeutics, ISSN: 00099236 15326535
MacHavaram; Lisa M. Almond; Amin Rostami-Hodjegan; Iain Gardner; Masoud Jamei; Suzanne Tay; Susan C. Wong; Amita Joshi; Jane R. Kenny
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Laurent Claret; Manish Gupta; Kelong Han; Amita Joshi; Nenad Sarapa; Jing He; Bob Powell; Rene Bruno
Investigative Ophthalmology and Visual Science, ISSN: 01460404 15525783
Lu Xu; Tong Lu; Lisa Tuomi; Nelson L'ntshotsholé Jumbe; Jian-Feng Lu; Stephen M. Eppler; Peter Kuebler; Lisa A. Damico; Amita Joshi
Pharmaceutical Biotechnology: Fundamentals and Applications, Fourth Edition,
John Davis; Rong Deng; C. Andrew Boswell; Yi Zhang; Jing Li; Fielder; Amita Joshi; Sara Kenkare-Mitra
Clinical Pharmacology in Drug Development, ISSN: 2160763X 21607648
Manish Gupta; Wang; Timothy J. Carrothers; Patricia M. LoRusso; Yu-Waye Chu; Ted Shih; David Loecke; Amita Joshi; Ola M. Saad; Joo-Hee Yi; Sandhya Girish
Journal of Clinical Pharmacology, ISSN: 00912700 15524604
Jing Li; Jianguo Zhi; Michael Wenger; Nancy Valente; Anna Dmoszynska; Tadeusz Robak; Ranvir Mangat; Amita Joshi; Jennifer Visich
Cancer Chemotherapy and Pharmacology, ISSN: 03445704 14320843
Brendan C. Bender; Franziska Schaedeli-Stark; Reinhold Koch; Amita Joshi; Yu-Waye Chu; Hope S. Rugo; Ian E. Krop; Sandhya Girish; Lena E. Friberg; Manish Gupta
Current Drug Metabolism, ISSN: 13892002 18755453
Dan Lu; Howard A. Burris; Wang; E. Claire Dees; Javier Cortés; Amita Joshi; Manish Gupta; Joo-Hee Yi; Yu-Waye Chu; Ted Shih; Liang Fang; Sandhya Girish
Pharmaceutical Research, ISSN: 07248741 1573904X
Yan Xin; Shuang Bai; Lisa A. Damico; Denise Jin; Wei-Ching Liang; Yan Wu; Frank-Peter Theil; Amita Joshi; Yanmei Lu; John Lowe; Mauricio Maia; Rainer Brachmann; Hong Xiang
Cancer Chemotherapy and Pharmacology, ISSN: 03445704 14320843
Sandhya Girish; Manish Gupta; Wang; Dan Lu; Ian E. Krop; Charles L. Vogel; Howard A. Burris; Patricia M. LoRusso; Joo-Hee Yi; Ola M. Saad; Barbara Tong; Yu-Waye Chu; Scott N. Holden; Amita Joshi
Journal of Clinical Pharmacology, ISSN: 00912700 15524604
Manish Gupta; Patricia M. LoRusso; Wang; Joo-Hee Yi; Howard A. Burris; Muralidhar Beeram; Shanu Modi; Yu-Waye Chu; Samuel Agresta; Barbara Klencke; Amita Joshi; Sandhya Girish
Journal of Pharmacokinetics and Pharmacodynamics, ISSN: 1567567X 15738744
Yan Xin; Hong Xiang; Denise Jin; Frank-Peter Theil; Amita Joshi; Lisa A. Damico; Shuang Bai
Clinical Pharmacokinetics, ISSN: 03125963 11791926
Shuang Bai; Karin Jorga; Yan Xin; Denise Jin; Zheng; Lisa A. Damico; Manish Gupta; Meina Tao Tang; David E. Allison; Dan Lu; Yi Zhang; Amita Joshi; Mark J. Dresser
mAbs, ISSN: 19420870 19420862
Zheng; Devin B. Tesar; Lisa Benincosa; Herbert F. Birnböck; C. Andrew Boswell; Daniela Bumbaca; Kyra J. Cowan; Dimitry Danilenko; Daugherty; Fielder; Hans Peter Grimm; Amita Joshi; Nicole Justies; Gerry Kolaitis; Nicholas Lewin-Koh; Jing Li; Sami McVay; Jennifer O'Mahony; Michael Otteneder; Michael P. Pantze; Wendy Putnam; Zhihua Julia Qiu; Jane Ruppel; Thomas Singer; Oliver B. Stauch; Frank-Peter Theil; Jennifer Visich; Yang; Yong Ying; Leslie A. Khawli; Wolfgang F. Richter
AAPS Journal, ISSN: 15507416
Sandhya Girish; Steven W Martin; Mark C Peterson; Lei K. Zhang; Hong Zhao; Joseph P. Balthasar; Raymond Evers; Honghui Zhou; Min Zhu; Lewis Klunk; Chao Han; Eva Gil Berglund; Huang; Amita Joshi
Therapeutic Delivery, ISSN: 20415990 20416008
Saileta Prabhu; C. Andrew Boswell; Douglas Leipold; Leslie A. Khawli; Dongwei Li; Dan Lu; Frank-Peter Theil; Amita Joshi; Bert L. Lum
mAbs, ISSN: 19420862
Leslie A. Khawli; Sirj Goswami; Ryan Hutchinson; Zephania Kwong Glover; Yang; Xiangdan Wang; Zhenling Yao; Alavattam Sreedhara; Tony Cano; Devin B. Tesar; Ihsan Nijem; David E. Allison; Wong; Kao; Quan; Amita Joshi; Reed J. Harris; Paul Motchnik
Proteins and Peptides: Pharmacokinetic, Pharmacodynamic, and Metabolic Outcomes,
C. Andrew Boswell; Rong Deng; Kedan Lin; Wendy Putnam; Cherry Lei; Frank-Peter Theil; Amita Joshi; Fielder; Leslie A. Khawli
AAPS Journal, ISSN: 15507416
Wendy Putnam; Jing Li; Jonas Haggstrom; Chee Ng; Saloumeh Kadkhodayan Fischer; Melissa Cheu; Yamo Deniz; Henry B. Lowman; Fielder; Jennifer Visich; Amita Joshi; Nelson L'ntshotsholé Jumbe
AAPS Journal, ISSN: 15507416
Marilyn N. Martinez; Peter Bonate; Robert L. Chapman; Anne De Groot; Susan D'Souza; Naushad Ghilazi; Vivian Gray; Vishal K. Gupta; Kim Huynh-Ba; Sunil Iyer; Arya Jayatilaka; Amita Joshi; H. Thomas Karnes; Mansoor Khan; Patrick Liu; Craig Lunte; Christopher R. McCurdy; Marilyn E. Morris; Kenneth J. Norris; Phillip Ramsey; Sanjay Sehgal; Manuel Zahn
Journal of Clinical Pharmacology, ISSN: 00912700 15524604
Amita Joshi; Bauer; Peter Kuebler; Mark White; Cecilia Leddy; Peter Compton; Marvin Garovoy; Paul Kwon; Patricia Walicke; Russell L Dedrick
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Benjamin Wu; Amita Joshi; Song Ren; Chee Ng
Pharmaceutical Research, ISSN: 07248741 1573904X
Chee Ng; Amita Joshi; Russell L Dedrick; Marvin Garovoy; Bauer
Journal of Clinical Pharmacology, ISSN: 00912700
Sun; Jian-Feng Lu; Amita Joshi; Peter Compton; Paul Kwon; Rene Bruno
Journal of Clinical Pharmacology, ISSN: 00912700
Deborah L. Mortensen; Patricia Walicke; Xiaolin Wang; Paul Kwon; Peter Kuebler; Alice Gottlieb; James G. Krueger; Craig Leonardi; Bruce Miller; Amita Joshi
Regulatory Toxicology and Pharmacology, ISSN: 02732300
Janet Clarke; Will Leach; Susanne Pippig; Amita Joshi; Benjamin Wu; Robert House; Joseph Beyer
Dermatology, ISSN: 10188665
Jullien; Prinz; Richard G. B. Langley; Ivor Caro; Wolfgang Dummer; Amita Joshi; Russell L Dedrick; Natta
British Journal of Cancer, ISSN: 00070920
Goh; Vokes; Amita Joshi; Ratain
Drug Metabolism and Disposition, ISSN: 00909556
Amita Joshi; Pieniaszek H.J.; Vokes; Nicholas J. Vogelzang; Davidson; Richards; Chai; Finizio; Ratain
Education
- Grant Medical College, Department of Pharmacology, Bombay University, Clinical Pharmacology – 1995
- University of Texas at Austin, Ph.D. in Pharmacokinetics – 1990
- The Bombay College of Pharmacy, Bachelor of Pharmacy – 1983
Awards & Honors
- Malle Jurima–Romet Mid-Career Leadership, American Society of Clinical and Experimental Therapeutics – 2018
- Most Influential Women in Business, San Francisco Business Times – 2016
- Industry Leader, Professional Businesswoman of California – 2015
- Chair of the Conference Planning Committee, National Biotechnology Conference (NBC) of AAPS – 2010