Hanna Budayeva - Principal Scientist, Chemoproteomics, Proteomic and Genomic Technologies, Research Biology

Hanna Budayeva

Principal Scientist, Chemoproteomics, Proteomic and Genomic Technologies, Research Biology

Postdoc Mentor
"Fostering a collaborative and productive research environment is key to bridging research biology, discovery chemistry and proteomics, driving innovation and uncovering new possibilities in drug discovery."
9
Years at Genentech
1
Awards & Honors

My career journey in biomedical research began as a Graduate Research Assistant at Princeton University in the laboratory of Dr. Ileana Cristea, where I characterized new properties of sirtuin 2 using advanced mass spectrometry techniques. Following this, I joined the Discovery Proteomics group at Genentech as a Postdoctoral Fellow under the mentorship of Dr. Don Kirkpatrick, where I implemented workflows for proteome and post-translational modification profiling to study receptor activation and cellular signaling.

At Genentech, I advanced to the role of Principal Scientific Researcher, establishing new methods to increase sample throughput in chemoproteomics studies and contributing to target deconvolution for novel drug modalities. Currently, I lead a chemoproteomics team, developing innovative methodologies and fostering collaborations to assess the activity and potential of chemical entities in drug discovery.

Postdoctoral Mentor

Having been a postdoc at Genentech myself, I've seen firsthand how cross-functional collaborations are pivotal to driving successful projects. This experience has fueled my motivation to mentor postdocs within the program, giving them opportunities to see how basic research can seamlessly translate into the discovery of new drugs.

By fostering connections across various departments, postdocs can gain a holistic understanding of how interdisciplinary efforts contribute to innovation. I aim to guide them in embracing these collaborations, helping them to appreciate the broader impact of their research and empowering them to become influential contributors in the field of drug discovery.

Featured Publication

Monitoring protein communities and their responses to therapeutics.

Nat. Rev. Drug Discov. (2020) Jun;19(6):414-426.

Budayeva HG, Kirkpatrick DS.