Teemu Junttila
Distinguished Scientist - Technology, Translational Oncology, Research Biology
18
Years at Genentech
21
Publications at Genentech
I joined Genentech in 2006, initially as a post doctoral fellow. I transitioned to leading a research team in 2010. What attracted me to Genentech the most, and still does, is the unique opportunity to be involved in a drug discovery project from concept all the way to clinical development. The immediate proximity between discovery scientists and clinical scientists allows for unique synergy - my research can be rapidly guided by clinical signals without delay, which I find extremely motivating and rewarding. My role is to lead large molecule biology research that translates new antibody engineering technologies into oncology therapeutics. Currently, we are focusing on bispecific antibodies that can be used to redirect T cells to attack tumors.
Featured Publication
Membrane-Proximal Epitope Facilitates Efficient T Cell Synapse Formation by Anti-FcRH5/CD3 and Is a Requirement for Myeloma Cell Killing.
Cancer Cell. 2017 Mar 13;31(3):383-395.
Li J, Stagg NJ, Johnston J, Harris MJ, Menzies SA, DiCara D, Clark V, Hristopoulos M, Cook R, Slaga D, Nakamura R, McCarty L, Sukumaran S, Luis E, Ye Z, Wu TD, Sumiyoshi T, Danilenko D, Lee GY, Totpal K, Ellerman D, Hötzel I, James JR, Junttila TT.
Genentech Publications
Molecular Cancer Therapeutics, ISSN: 15357163
Ji Li; Robyn Clark; Dionysos S. Slaga; Kendra N. Avery; Ke Liu; Suzanne Schubbert; Rajat Varma; Eugene Y. Chiang; Klara Totpal; Matthew Bernett; Patrick Holder; Teemu T. Junttila
Molecular Cancer Therapeutics,
Ji Li; Dionysos S. Slaga; Jennifer A. Johnston; Teemu T. Junttila
Molecular Cancer Therapeutics, ISSN: 15388514 15357163
Amy Lo; Jennifer A. Johnston; Ji Li; Danielle Mandikian; Maria Hristopoulos; Robyn Clark; Dorothee Nickles; Wei-Ching Liang; Kathy Hötzel; Debra Dunlap; Thinh Q. Pham; Hao Cai; Meric A. Ovacik; Daniel Bravo-Perez; Elaine Mai; Dionysos S. Slaga; Diego Ellerman; James Ziai; Klara Totpal; Genee Y. Lee; Andrew Boswell; Jian Payandeh; Yan Wu; Teemu T. Junttila
Target arm affinities determine preclinical efficacy and safety of anti-HER2/CD3 bispecific antibody
JCI insight, ISSN: 23793708
Karin Staflin; Christina L. Zuch de Zafra; Leah Schutt; Vanessa Clark; Fiona Zhong; Maria Hristopoulos; Robyn Clark; Ji Li; Mary Mathieu; Xiaocheng Chen; Jennifer A. Johnston; Justin Low; Ryan Ybarra; Dionysos S. Slaga; Yang; Meric A. Ovacik; Noel Dybdal; Klara Totpal; Melissa Junttila; Diego Ellerman; Genee Y. Lee; Dennis; Prell; Teemu T. Junttila
Cell Death and Differentiation, ISSN: 14765403 13509047
Jason E. Long; Matthew Wongchenko; Dorothee Nickles; Wei-Jen Chung; Bu-Er Wang; Johannes Riegler; Ji Li; Qingling Li; Wendy N. Sandoval; Jeffrey Eastham-Anderson; Zora Modrusan; Teemu T. Junttila; Richard A. D. Carano; Oded Foreman; Yibing Yan; Melissa Junttila
Science Translational Medicine, ISSN: 19466242 19466234
Ji Li; Robert Piskol; Ryan Ybarra; Ying-Jiun J. Chen; Jason Li; Dionysos S. Slaga; Maria Hristopoulos; Robyn Clark; Zora Modrusan; Klara Totpal; Melissa Junttila; Teemu T. Junttila
mAbs, ISSN: 19420870 19420862
Ayse Meric Ovacik; Ji Li; Marie Lemper; Dimitry Danilenko; Nicola J. Stagg; Mary Mathieu; Diego Ellerman; Vinita Gupta; Navdeep Kalia; Trung Nguy; Vicki Plaks; Clarissa David Johnson; Weiru Wang; Jochen Brumm; Bernard M. Fine; Teemu T. Junttila; Kedan Lin; Paul J. Carter; Saileta Prabhu; Christoph Spiess; Amrita Kamath
Clinical Cancer Research, ISSN: 15573265 10780432
Ji Li; Ryan Ybarra; Judy Mak; Aurelie Herault; Patricia De Almeida; Alfonso Arrazate; James Ziai; Klara Totpal; Melissa Junttila; Kevin B. Walsh; Teemu T. Junttila
Science Translational Medicine, ISSN: 19466242 19466234
Dionysos S. Slaga; Diego Ellerman; T. Noelle Lombana; Rajesh Vij; Ji Li; Maria Hristopoulos; Robyn Clark; Jennifer A. Johnston; Amy Shelton; Elaine Mai; Kapil Gadkar; Amy Lo; James T. Koerber; Klara Totpal; Prell; Genee Y. Lee; Christoph Spiess; Teemu T. Junttila
Molecular Cancer Therapeutics, ISSN: 15388514 15357163
Danielle Mandikian; Nene Takahashi; Amy Lo; Ji Li; Jeffrey Eastham-Anderson; Dionysos S. Slaga; Jason Ho; Maria Hristopoulos; Robyn Clark; Klara Totpal; Kedan Lin; Sean B. Joseph; Dennis; Saileta Prabhu; Teemu T. Junttila; C. Andrew Boswell
mAbs, ISSN: 19420870 19420862
Sanket Patke; Ji Li; Peiyin Wang; Dionysos S. Slaga; Jennifer A. Johnston; Sunil Bhakta; Siler Panowski; Liping L. Sun; Teemu T. Junttila; Justin M. Scheer; Diego Ellerman
Cancer Cell, ISSN: 18783686 15356108
Ji Li; Nicola J. Stagg; Jennifer A. Johnston; Michael J. Harris; Sam A. Menzies; Danielle DiCara; Vanessa Clark; Maria Hristopoulos; Ryan Cook; Dionysos S. Slaga; Rin Nakamura; Luke McCarty; Siddharth Sukumaran; Luis; Zhengmao Ye; Thomas D Wu; Teiko Sumiyoshi; Dimitry Danilenko; Genee Y. Lee; Klara Totpal; Diego Ellerman; Isidro Hötzel; John R. James; Teemu T. Junttila
mAbs, ISSN: 19420870 19420862
Michael Dillon; Yiyuan Yin; Jianhui Zhou; Luke McCarty; Diego Ellerman; Dionysos S. Slaga; Teemu T. Junttila; Guanghui Han; Wendy N. Sandoval; Meric A. Ovacik; Kedan Lin; Zhilan Hu; Amy Shen; Jacob E. Corn; Christoph Spiess; Paul J. Carter
Science Translational Medicine, ISSN: 19466242 19466234
Liping L. Sun; Diego Ellerman; Mary Mathieu; Maria Hristopoulos; Xiaocheng Chen; Yijin Li; Xiaojie Yan; Robyn Clark; Arthur Reyes; Stefanich; Elaine Mai; Judy Young; Clarissa Johnson; Mahrukh Huseni; Xinhua Wang; Chen; Peiyin Wang; Hong Wang; Noel Dybdal; Yu-Waye Chu; Nicholas Chiorazzi; Justin M. Scheer; Teemu T. Junttila; Klara Totpal; Dennis; Allen Ebens
Cancer immunology research, ISSN: 23266074 23266066
Scot D. Liu; Cecile Chalouni; Judy Young; Teemu T. Junttila; Mark X. Sliwkowski; John Lowe
Cancer Research, ISSN: 15387445 00085472
Teemu T. Junttila; Ji Li; Jennifer A. Johnston; Maria Hristopoulos; Robyn Clark; Diego Ellerman; Bu-Er Wang; Yijin Li; Mary Mathieu; Guangmin Li; Judy Young; Luis; Gail L. Phillips; Stefanich; Christoph Spiess; Andrew G. Polson; Bryan Irving; Justin M. Scheer; Melissa Junttila; Dennis; Robert F. Kelley; Klara Totpal; Allen Ebens
Breast Cancer Research and Treatment, ISSN: 01676806 15737217
Teemu T. Junttila; Guangmin Li; Kathryn Parsons; Gail L. Phillips; Mark X. Sliwkowski
Duodecim; lääketieteellinen aikakauskirja, ISSN: 00127183
Teemu T. Junttila; Minna Tanner; Jorma Isola
Cancer Cell, ISSN: 18783686 15356108
Teemu T. Junttila; Robert W. Akita; Kathryn Parsons; Carter Fields; Gail L. Phillips; Lori S. Friedman; Deepak Sampath; Mark X. Sliwkowski
Cancer Research, ISSN: 00085472 15387445
Teemu T. Junttila; Kathryn Parsons; Christine Olsson; Yanmei Lu; Yan Xin; Julie Theriault; Lisa Crocker; Oliver Pabonan; Tomasz K. Baginski; Meng; Klara Totpal; Robert F. Kelley; Mark X. Sliwkowski
Cancer Cell, ISSN: 15356108
Teemu T. Junttila; Robert W. Akita; Kathryn Parsons; Carter Fields; Gail L. Phillips; Lori S. Friedman; Deepak Sampath; Mark X. Sliwkowski
Education
- University of Turku, Finland , PhD in Medical Biochemistry – 2005