Vincent Lemaire
Senior Principal Scientist Modeling & Simulation, Clinical Pharmacology, Development Sciences
Postdoc Mentor
"Nothing in Nature functions in isolation, systems need to be considered as a whole, although not necessarily in every details. Mathematical models provide a way to capture the essence of interactions and behaviors of a complex system, which can then be systematically interrogated to generate new insight and guidance."
8
Years at Genentech
5
Publications at Genentech
4
Awards & Honors
I joined Genentech in February 2016 in the Modeling & Simulation group within Clinical Pharmacology, as a growing effort to expand the impact of Quantitative Systems Pharmacology (QSP) in the clinical development of our compounds. Our approach relies on a variety of quantitative methods such as mechanisms-based modeling, disease and pathway modeling, PKPD modeling, or any other quantitative approach that will help answer our questions of interest with speed and reliability. Being part of Clinical Pharmacology, the focus is on questions related to human dose selection, dose scheduling optimization, biomarkers characterization, treatment duration determination and patients stratification.
Featured Publication
Modeling the interactions between osteoblast and osteoclast activities in bone remodeling.
J Theor Biol. 2004 Aug 7;229(3):293-309.