Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10551 - 10600 OF 15583 RESULTS

Asthma in older adults: Observations from the Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study
Annals of Allergy, Asthma and Immunology, ISSN: 10811206
Raymond G. Slavin; Tmirah Haselkorn; June H. Lee; Zheng; Yamo Deniz; Sally E. Wenzel
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Survivin expression in breast cancer predicts clinical outcome and is associated with HER2, VEGF, urokinase plasminogen activator and PAI-1
Annals of Oncology, ISSN: 15698041 09237534
Brid M. Ryan; Gottfried E. Konecny; Kahlert; Wang; Untch; Meng; Pegram; Podratz; John Crown; Dennis J. Slamon; Duffy
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Potential inhibitors of chemokine function: Analysis of noncovalent complexes of CC chemokine and small polyanionic molecules by ESI FT-ICR mass spectrometry
Journal of the American Society for Mass Spectrometry, ISSN: 10440305
Yonghao Yu; Matthew D. Sweeney; Ola M. Saad; Julie A. Leary
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Tolerability and Efficacy of Multiple Escalating Doses of Ranibizumab (Lucentis) for Neovascular Age-Related Macular Degeneration
Ophthalmology, ISSN: 01616420
Philip J. Rosenfeld; Jeffrey S. Heier; Gary Hantsbarger; Naveed Shams
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Ranibizumab for Treatment of Neovascular Age-Related Macular Degeneration. A Phase I/II Multicenter, Controlled, Multidose Study
Ophthalmology, ISSN: 01616420
Jeffrey S. Heier; Andrew N. Antoszyk; Peter Reed Pavan; Steven R. Leff; Philip J. Rosenfeld; Thomas A. Ciulla; Richard F. Dreyer; Ronald C. Gentile; Judy P. Sy; Gary Hantsbarger; Naveed Shams
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Apples and oranges: Comparing computer systems audits
Drug Information Journal, ISSN: 00928615
Jacques Mourrain
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The application of mechanism-based PK/PD modeling in pharmacodynamic-based dose selection of muM17, a surrogate monoclonal antibody for efalizumab
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Benjamin Wu; Amita Joshi; Song Ren; Chee Ng
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Evaluation of erlotinib in advanced non-small cell lung cancer: Impact on the budget of a U.S. health insurance plan
Journal of Managed Care Pharmacy, ISSN: 10834087
Scott D. Ramsey; Lauren Clarke; Tripthi V. Kamath; Deborah Lubeck
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Is tobacco use a problem among deaf college students?
American Annals of the Deaf, ISSN: 0002726X
Barbara A. Berman; Coen A. Bernaards; Elizabeth A. Eckhardt; Heidi B. Kleiger; Lauren Maucere; Leanne Streja; Glenn Wong; Shari Barkin; Roshan Bastani
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Design, synthesis, and biological activity of a potent Smac mimetic that sensitizes cancer cells to apoptosis by antagonizing IAPs.
ACS Chemical Biology, ISSN: 15548937
Zobel; Lan Wang; Eugene Varfolomeev; Matthew C Franklin; Linda O. Elliott; Heidi J. A. Wallweber; David C Okawa; Flygare; Domagoj Vucic; Wayne J. Fairbrother; Deshayes
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Regulation of ERK3/MAPK6 expression by BRAF
International Journal of Oncology, ISSN: 17912423 10196439
Klaus P. Hoeflich; Mike Eby; William F. Forrest; Daniel C. Gray; Janet Y. Tien; Howard M. Stern; Lesley J. Murray; David P. Davis; Zora Modrusan; Somasekar Seshagiri
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Targeted therapies in solid tumors: Monoclonal antibodies and small molecules
Human Antibodies, ISSN: 10932607
Louis M. Weiner; Hossein Borghaei
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Formulation considerations for proteins susceptible to asparagine deamidation and aspartate isomerization
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Aditya A. Wakankar; Ronald T. Borchardt
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Paracrine VEGF/VE-cadherin action on ovarian cancer permeability
Experimental Biology and Medicine, ISSN: 15353699 15353702
Limin Hu; Napoleone Ferrara; Robert B. Jaffe
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Longitudinal differences in psychological outcomes for Men with erectile dysfunction: Results from ExCEED™
Journal of Sexual Medicine, ISSN: 17436109 17436095
David M. Latini; David F. Penson; Katrine L. Wallace; Deborah Lubeck; Tom F. Lue
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Clinical and psychosocial characteristics of men with erectile dysfunction: Baseline data from ExCEED™
Journal of Sexual Medicine, ISSN: 17436109 17436095
David M. Latini; David F. Penson; Katrine L. Wallace; Deborah Lubeck; Tom F. Lue
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Synthetic therapeutic antibodies
Nature Chemical Biology, ISSN: 15524469 15524450
Sachdev S. Sidhu; Frederic A. Fellouse
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Nontraditional roles for certified pharmacy technicians in a pharmaceutical company
Journal of the American Pharmacists Association, ISSN: 15443450 15443191
Stacey M. Fung; Christine Gilmour; David McCracken; Korban Shane; Gary Matsuura
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Large-scale trends in the evolution of gene structures within 11 animal genomes
PLoS Computational Biology, ISSN: 15537358 1553734X
Mark Yandell; Chris J. Mungall; Chris Smith; Simon Prochnik; Joshua S. Kaminker; George Hartzell; Suzanna E. Lewis; Gerald M. Rubin
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TGF-β regulates the mechanical properties and composition of bone matrix
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Guive Balooch; Mehdi Balooch; Ravi K. Nalla; Stephen Schilling; Ellen H. Filvaroff; Grayson W. Marshall; Sally J. Marshall; Robert O. Ritchie; Rik Derynck; Tamara Alliston
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Increase in TNF-α and inducible nitric oxide synthase-expressing dendritic cells in psoriasis and reduction with efalizumab (anti-CD11a)
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Michelle A. Lowes; Francesca Chamian; Maria V. Abello; Judilyn Fuentes-Duculan; Shao-Lee Lin; Rachel Nussbaum; Inna Novitskaya; Henrietta Carbonaro; Irma Cardinale; Toyoko Kikuchi; Patricia Gilleaudeau; Mary Sullivan-Whalen; Knut Wittkowski; Kim Papp; Marvin Garovoy; Wolfgang Dummer; Ralph M. Steinman; James G. Krueger
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Identification of the minimal protein domain required for priming activity of munc13-1
Current Biology, ISSN: 09609822
David R. Stevens; Zheng-Xing Wu; Ulf Matti; Harald Junge; Claudia Schirra; Ute Becherer; Sonja M. Wojcik; Nils Brose; Jens Rettig
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Epithelial versus mesenchymal phenotype determines in vitro sensitivity and predicts clinical activity of erlotinib in lung cancer patients
Clinical Cancer Research, ISSN: 10780432
Robert Yauch; Thomas Januario; Eberhard; Guy Cavet; Wenjing Zhu; Ling Fu; Thinh Q. Pham; Robert Soriano; Stinson; Somasekar Seshagiri; Zora Modrusan; Chin-Yu Lin; Vincent O'Neill; Lukas Amler
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Angiogenesis as a therapeutic target
Nature, ISSN: 00280836 14764679
Napoleone Ferrara; Robert S. Kerbel
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MORT1/FADD is involved in liver regeneration
World Journal of Gastroenterology, ISSN: 10079327
Marcus Schuchmann; Felix Rückert; Jose F. Garcia-Lazaro; Andrea Karg; Jürgen Burg; Natalia Knorr; Jürgen Siebler; Eugene Varfolomeev; David Wallach; Wolfgang Schreiber; Ansgar W. Lohse; Peter R. Galle
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Oxidizing potential of endosomes and lysosomes limits intracellular cleavage of disulfide-based antibody-drug conjugates
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Cary D. Austin; Xiaohui Wen; Lewis Gazzard; Nelson; Richard H. Scheller; Suzie J. Scales
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Interspecies exchange mutagenesis of the first epidermal growth factor-like domain of human factor VII
Journal of Thrombosis and Haemostasis, ISSN: 15387933 15387836
Williamson; Pyke; Sampath Sridhara; Robert F. Kelley; Morris A. Blajchman; Bryan J. Clarke
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Molecular determinants of kinase pathway activation by Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Eugene Varfolomeev; Heather Maecker; Darcie Sharp; David Lawrence; Renz; Domagoj Vucic; Avi Ashkenazi
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A smooth operator for LPS responses
Nature Immunology, ISSN: 15292908 15292916
Godowski
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P63 is an essential proapoptotic protein during neural development
Neuron, ISSN: 08966273
W. Bradley Jacobs; Gregory Govoni; Daniel Ho; Jasvinder K. Atwal; Fanie Barnabe-Heider; William M. Keyes; Alea A. Mills; Freda D. Miller; David R. Kaplan
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TWEAK attenuates the transition from innate to adaptive immunity
Cell, ISSN: 00928674
Heather Maecker; Eugene Varfolomeev; Frank C. Kischkel; David Lawrence; Heidi LeBlanc; Wyne P. Lee; Stephen D. Hurst; Dimitry Danilenko; Jun Li; Ellen H. Filvaroff; Becky Yang; Dylan Daniel; Avi Ashkenazi
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Phase I clinical study of pertuzumab, a novel HER dimerization inhibitor, in patients with advanced cancer
Journal of Clinical Oncology, ISSN: 0732183X
David B. Agus; Michael S. Gordon; Charles Taylor; Ronald B. Natale; Beth Karlan; David Mendelson; Michael F. Press; David E. Allison; Mark X. Sliwkowski; Grade Lieberman; Stephen Kelsey; Gwendolyn Fyfe
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Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib
Journal of Clinical Oncology, ISSN: 0732183X
Eberhard; Bruce E. Johnson; Lukas Amler; Goddard; Sherry Heldens; Roy S. Herbst; William Ince; Pasi A. Jänne; Thomas Januario; David H. Johnson; Pam Klein; Vincent A. Miller; Michael Ostland; David A. Ramies; Dragan Sebisanovic; Stinson; Zhang; Somasekar Seshagiri; Kenneth J. Hillan
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UV microscopy at 280 nm is effective in screening for the growth of protein microcrystals
Journal of Applied Crystallography, ISSN: 00218898 16005767
Christopher S. Lunde; Shahab Rouhani; Jonathan P. Remis; Steven E. Ruzin; James A. Ernst; Robert M. Glaeser
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Randomized phase III trial of capecitabine compared with bevacizumab plus capecitabine in patients with previously treated metastatic breast cancer
Journal of Clinical Oncology, ISSN: 0732183X
Kathy Miller; Linnea I. Chap; Frankie Ann Holmes; Melody A. Cobleigh; P. Kelly Marcom; Louis Fehrenbacher; Maura N. Dickler; Beth A. Overmoyer; Reimann; Amy Sing; Virginia K. Langmuir; Hope S. Rugo
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Combined analysis of efficacy: The addition of bevacizumab to fluorouracil/leucovorin improves survival for patients with metastatic colorectal cancer
Journal of Clinical Oncology, ISSN: 0732183X
Fairooz F. Kabbinavar; Julie Hambleton; Robert Mass; Herbert Hurwitz; Emily Bergsland; Somnath Sarkar
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Addition of bevacizumab to bolus fluorouracil and leucovorin in first-line metastatic colorectal cancer: Results of a randomized phase II trial
Journal of Clinical Oncology, ISSN: 0732183X
Fairooz F. Kabbinavar; Joseph Schulz; Michael McCleod; Taral Patel; John T. Hamm; Joel Randolph Hecht; Robert Mass; Brent Perrou; Betty Nelson; Novotny
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Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib
Journal of Clinical Oncology, ISSN: 0732183X
Eberhard; Bruce E. Johnson; Lukas Amler; Goddard; Sherry Heldens; Roy S. Herbst; William L. Ince; Pasi A. Jänne; Thomas Januario; David H. Johnson; Pam Klein; Vincent A. Miller; Michael Ostland; David A. Ramies; Dragan Sebisanovic; Stinson; Zhang; Somasekar Seshagiri; Kenneth J. Hillan
View on Scopus
Phase I clinical study of pertuzumab, a novel HER dimerization inhibitor, in patients with advanced cancer
Journal of Clinical Oncology, ISSN: 0732183X
Agus; Michael S. Gordon; Charles Taylor; Ronald B. Natale; Beth Karlan; David Mendelson; Michael F. Press; David E. Allison; Mark X. Sliwkowski; Grade Lieberman; Stephen Kelsey; Gwendolyn Fyfe
View on Scopus
Inhibition of collagen gene expression in systemic sclerosis dermal fibroblasts by mithramycin
Annals of the Rheumatic Diseases, ISSN: 00034967
Sandorfi; Louneva; Hitraya; Hajnoczky; Saitta; Sergio A. Jimenez
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Predicting clinical benefit in non-small-cell lung cancer patients treated with epidermal growth factor tyrosine kinase inhibitors
Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451
Lukas Amler; Goddard; Kenneth J. Hillan
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Minimally important differences were estimated for the Functional Assessment of Cancer Therapy-Colorectal (FACT-C) instrument using a combination of distribution- and anchor-based approaches
Journal of Clinical Epidemiology, ISSN: 08954356
Yost; Cella; Chawla; Holmgren; Eton; Ayanian; West
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Symptom control and improved functioning: The effect of omalizumab on Asthma-Related Quality of Life (ARQL)
Journal of Asthma, ISSN: 02770903 15324303
Allan T. Luskin; Mark Kosinski; Bresnahan; Ashby; Dennis A. Wong
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Safety of efalizumab in patients with moderate to severe chronic plaque psoriasis: Review of clinical data. Part II
Journal of Cutaneous Medicine and Surgery, ISSN: 12034754
Kim Papp; Charles Camisa; Stephen P. Stone; Ivor Caro; Xiaolin Wang; Peter Compton; Patricia Walicke; Alice Gottlieb
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Clinical efficacy of efalizumab in patients with chronic plaque psoriasis: Results from three randomized placebo-controlled phase III trials: Part I
Journal of Cutaneous Medicine and Surgery, ISSN: 12034754
David M. Pariser; Kenneth B. Gordon; Kim Papp; Craig Leonardi; Paul Kwon; Peter Compton; Amy Chen Rundle; Patricia Walicke; Mark Lebwohl
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Strategies for developing a successful electronic submission
American Pharmaceutical Review, ISSN: 10998012
Pawson
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Impaired skin barrier function in dermatologic disease and repair with moisturization
Cutis, ISSN: 00114162
Mark Lebwohl; Lisa G. Herrmann
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Efficacy of a long-acting growth hormone (GH) preparation in patients with adult GH deficiency
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X 0021972X
Andrew R. Hoffman; Beverly M. K. Biller; David Cook; Joyce Baptista; Bernard L. Silverman; Dao; Kenneth M. Attie; Fielder; Thomas J. Maneatis; Barbara M. Lippe
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Proteomics
Methods in Enzymology, ISSN: 00766879
Stults; David Arnott
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Isolation and culture of hair cell progenitors from postnatal rat cochleae
Journal of Neurobiology, ISSN: 00223034
Suo-qiang Zhai; Li Shi; Bu-Er Wang; Gui-liang Zheng; Wei Song; Yin-yan Hu; Gao
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