Genentech: Publications

March 1, 2005

Pharmacokinetics and pharmacodynamics of multiple weekly subcutaneous efalizumab doses in patients with plaque psoriasis

Journal of Clinical Pharmacology, ISSN: 00912700

Deborah L. Mortensen; Patricia Walicke; Xiaolin Wang; Paul Kwon; Peter Kuebler; Alice Gottlieb; James G. Krueger; Craig Leonardi; Bruce Miller; Amita Joshi

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March 1, 2005

1H, 13C, and 15N resonance assignments of SAP18 [1]

Journal of Biomolecular NMR, ISSN: 09252738

Scott A. McCallum; Jianping Yin; Wayne J. Fairbrother

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March 1, 2005

αvβ3 antagonists based on a central benzoic acid scaffold

Polish Journal of Chemistry, ISSN: 01375083

Will; Breipohl; Gourvest; Ruxer; Doucet; Auberval; Roland Baron; Gaillard; Thomas Gadek; Knolle; Stilz; Peyman

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March 1, 2005

Effect of copper sulfate on performance of a serum-free CHO cell culture process and the level of free thiol in the recombinant antibody expressed

Biotechnology Progress, ISSN: 87567938

Wendy B. Chaderjian; Chin; Reed J. Harris; Etcheverry

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March 1, 2005

The mitochondrial inner membrane protein mitofilin controls cristae morphology

Molecular Biology of the Cell, ISSN: 10591524

George B. John; Yonglei Shang; Li Li; Christian Renken; Carmen A. Mannella; Jeanne M. L. Selker; Linda Rangell; Michael J. Bennett; Jiping Zha

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February 25, 2005

Structures of APRIL-receptor complexes: Like BCMA, TACI employs only a single cysteine-rich domain for high affinity ligand binding

Journal of Biological Chemistry, ISSN: 00219258

Sarah G. Hymowitz; Darshana Patel; Heidi J. A. Wallweber; Steven T. Runyon; Minhong Yan; Jianping Yin; Stephanie K. Shriver; Nathaniel C. Gordon; Borlan Pan; Nicholas J. Skelton; Robert F. Kelley; Melissa A. Starovasnik

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February 21, 2005

A phase I study of dexosome immunotherapy in patients with advanced non-small cell lung cancer

Journal of Translational Medicine, ISSN: 14795876 14795876

Michael A. Morse; Jennifer Garst; Takuya Osada; Shubi Khan; Amy Hobeika; Timothy M. Clay; Nancy Valente; Revati Shreeniwas; Mary Ann Sutton; Alain Delcayre; Di-Hwei Hsu; Jean-Bernard Le Pecq; H. Kim Lyerly

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February 18, 2005

Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels

Journal of Biological Chemistry, ISSN: 00219258

Anne-Laure Perraud; Christina L. Takanishi; Betty Shen; Shin Kang; Megan K. Smith; Carsten Schmitz; Heather M. Knowles; Dana Ferraris; Weixing Li; Jie Zhang; Barry L. Stoddard; Andrew M. Scharenberg

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February 17, 2005

Differential requirement for Plexin-A3 and -A4 in mediating responses of sensory and sympathetic neurons to distinct class 3 Semaphorins

Neuron, ISSN: 08966273

Avraham Yaron; Pei-Hsin Huang; Hwai-Jong Cheng; Marc Tessier-Lavigne

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February 16, 2005

Triple knock-out of CNTF, LIF, and CT-1 defines cooperative and distinct roles of these neurotrophic factors for motoneuron maintenance and function

Journal of Neuroscience, ISSN: 02706474

Bettina Holtmann; Stefan Wiese; Mohtashem Samsam; Katja Grohmann; Diane Pennica; Rudolf Martini; Michael Sendtner

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February 15, 2005

Semi-parametric and non-parametric methods for clinical trials with incomplete data

Statistics in Medicine, ISSN: 02776715

O'Brien; David Zhang; Kent R. Bailey

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February 1, 2005

Preclinical pharmacokinetics of ranibizumab (rhuFabV2) after a single intravitreal administration

Investigative Ophthalmology and Visual Science, ISSN: 01460404

Jacques Gaudreault; David T.W. Fei; Jeriza Rusit; Pamela Suboc; Vanessa Shiu

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February 1, 2005

Nitration and increased α-synuclein expression associated with dopaminergic neurodegeneration in equine pituitary pars intermedia dysfunction

Journal of Neuroendocrinology, ISSN: 09538194

Dianne McFarlane; Noel Dybdal; Donaldson; Lisa M. Miller; Alastair E. Cribb

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February 1, 2005

Review: Clonidine is more effective than placebo for long term smoking cessation, but has side effects

Evidence-Based Medicine, ISSN: 13565524

Steven G. Gourlay; Stead; Neal L. Benowitz; Charles J. Bentz

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February 1, 2005

The FIP3-Rab11 protein complex regulates recycling endosome targeting to the cleavage furrow during late cytokinesis

Molecular Biology of the Cell, ISSN: 10591524

Gayle M. Wilson; Andrew B. Fielding; Glenn C. Simon; Xinzi Yu; Paul D. Andrews; Rebecca S. Haines; Andrew M. Frey; Andrew A. Peden; Gwyn W. Gould; Rytis Prekeris

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February 1, 2005

Characterization of alteplase (tPA) following delivery through the AngioJet rheolytic catheter

Journal of Endovascular Therapy, ISSN: 15266028

Charles P. Semba; Weck; Mahmood K Razavi; Cindy M. Setum; Thomas W. Patapoff

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February 1, 2005

Pharmacology and pharmacodynamics of bevacizumab as monotherapy or in combination with cytotoxic therapy in preclinical studies

Cancer Research, ISSN: 00085472

Hans-Peter Gerber; Napoleone Ferrara

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January 25, 2005

Automated online liquid chromatographic/mass spectrometric metabolic study for prodrug stability

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences, ISSN: 15700232

Fran Lai; S. Cyrus Khojasteh

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January 25, 2005

Genetic deletion of the Nogo receptor does not reduce neurite inhibition in vitro or promote corticospinal tract regeneration in vivo

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Binhai Zheng; Jasvinder K. Atwal; Carole Ho; Lauren C Case; Xiao-Lin He; Garcia; Oswald Steward; Marc Tessier-Lavigne

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January 25, 2005

A coreceptor interaction between the CD28 and TNF receptor family members B and T lymphocyte attenuator and herpesvirus entry mediator

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Lino C. Gonzalez Jr.; Kelly M. Loyet; Jill Calemine-Fenaux; Vandana Chauhan; Bernd Wranik; Wenjun Ouyang; Dan L. Eaton

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January 21, 2005

Receptor-selective mutants of apoptosis-inducing ligand 2/tumor necrosis factor-related apoptosis-inducing ligand reveal a greater contribution of Death Receptor (DR) 5 than DR4 to apoptosis signaling

Journal of Biological Chemistry, ISSN: 00219258

Robert F. Kelley; Klara Totpal; Stephanie H. Lindstrom; Mary Mathieu; Karen L Billeci; Laura DeForge; Roger Pai; Sarah G. Hymowitz; Avi Ashkenazi

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January 15, 2005

Importance of cellular microenvironment and circulatory dynamics in B cell immunotherapy

Journal of Immunology, ISSN: 00221767

Qian Gong; Qinglin Ou; Shiming Ye; Wyne P. Lee; Jennine Cornelius; Laurie Diehl; Yu Lin Wei; Zhilan Hu; Yanmei Lu; Yongmei Chen; Yan Wu; Meng; Gribling; Zhonghua Lin; Kathy Nguyen; Thanhvien Tran; Yifan Zhang; Hugh Rosen; Flavius Martin; Andrew A. Chan

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January 1, 2005

Applications of NMR spectroscopy in biopharmaceutical product development

Analytical Techniques for Biopharmaceutical Development,

Kao; Wong; Vanderlaan

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January 1, 2005

Vascular bed-specific signaling and angiogenesis

Endothelial Cells in Health and Disease,

Napoleone Ferrara; Rui Lin; Jennifer Lecouter

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January 1, 2005

Industry-Based Medical Communications: Benchmarking Survey of Quality Assurance Practices

Therapeutic Innovation and Regulatory Science, ISSN: 21684790

S. Justin Hileman; Graham; Joyce Serrano Martin; Barry Grobman

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January 1, 2005

Toward Small–Molecule Agonists of Tnf Receptors

Nature Chemical Biology, ISSN: 15524469 15524450

Sarah G. Hymowitz; Avi Ashkenazi

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January 1, 2005

Cell Culture Engineering IX

Biotechnology Progress, ISSN: 87567938

Octavio T. Ramírez; James M. Piret; Lynne Krummen; Konstantin Konstantinov

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January 1, 2005

Efficacy and safety results of long-term growth hormone treatment of idiopathic short stature

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X 0021972X

Stephen F. Kemp; Joyce Kuntze; Kenneth M. Attie; Thomas J. Maneatis; Butler; James W. Frane; Barbara M. Lippe

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January 1, 2005

Constitutive NF-κB activation by the t(11;18)(q21;q21) product in MALT lymphoma is linked to deregulated ubiquitin ligase activity

Cancer Cell, ISSN: 15356108

Honglin Zhou; Ming-Qing Du; Vishva M. Dixit

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January 1, 2005

Trials in the real world

Good Clinical Practice Journal, ISSN: 13500961

Elizabeth Tschosik; Susan Morris

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January 1, 2005

Mouse Disp1 is required in sonic hedgehog-expressing cells for paracrine activity of the cholesterol-modified ligand

Development (Cambridge), ISSN: 09501991

Hua Tian; Juhee Jeong; Brian D. Harfe; Clifford J. Tabin; Andrew P. McMahon

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January 1, 2005

Evaluation of clinical outcomes according to HER2 detection by fluorescence in situ hybridization in women with metastatic breast cancer treated with trastuzumab

Clinical Breast Cancer, ISSN: 15268209

Robert Mass; Michael F. Press; Steven M. Anderson; Melody A. Cobleigh; Charles L. Vogel; Noel Dybdal; Grazyna Leiberman; Dennis J. Slamon; Virginia Paton

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January 1, 2005

Comparison of EP "Heavy Metals" test with USP "Conductivity" test

Pharmaceutical Technology, ISSN: 15432521

George Torres; Arlene Arsitio; Carole Genovesi

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January 1, 2005

Engineering ML-IAP to produce an extraordinarily potent caspase 9 inhibitor: Implications for Smac-dependent anti-apoptotic activity of ML-IAP

Biochemical Journal, ISSN: 02646021

Domagoj Vucic; Matthew C Franklin; Heidi J. A. Wallweber; Kanad Das; Brendan P. Eckelman; Hwain Shin; Linda O. Elliott; Saloumeh Kadkhodayan; Deshayes; Guy S. Salvesen; Wayne J. Fairbrother

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January 1, 2005

POLO kinase regulates the Drosophila centromere cohesion protein MEI-S332

Developmental Cell, ISSN: 15345807

Astrid S. Clarke; Tracy Tzu-Ling Tang; Danny Liang-Yee Ooi; Terry L. Orr-Weaver

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January 1, 2005

The role of VEGF in the regulation of physiological and pathological angiogenesis.

EXS, ISSN: 1023294X

Napoleone Ferrara

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January 1, 2005

Gradient projection algorithms and software for arbitrary rotation criteria in factor analysis

Educational and Psychological Measurement, ISSN: 00131644

Coen A. Bernaards; Robert I. Jennrich

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January 1, 2005

Efficacy and safety observed during 24 weeks of efalizumab therapy in patients with moderate to severe plaque psoriasis

Archives of Dermatology, ISSN: 0003987X

Alan Menter; Kenneth B. Gordon; Wayne Carey; Tiffani K. Hamilton; Scott Glazer; Ivor Caro; Nicole F. Li; Wayne P. Gulliver

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January 1, 2005

The changing role of thrombolytic therapy in the management of acute deep vein thrombosis

Therapy, ISSN: 14750708

Mahmood K Razavi; Charles P. Semba

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January 1, 2005

Are inflammatory cytokines the common link between cancer-associated cachexia and depression?

Journal of Supportive Oncology, ISSN: 15446794

James Illman; Robert Corringham; Don Robinson Jr.; Hugh M. Davis; Jean-Francois Rossi; Cella; Mohit Trikha

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January 1, 2005

Industry-based medical communications: Benchmarking survey of quality assurance practices

Drug Information Journal, ISSN: 00928615

S. Justin Hileman; Graham; Joyce Serrano Martin; Barry Grobman

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January 1, 2005

The anti-inflammatory effects of omalizumab confirm the central role of IgE in allergic inflammation

Journal of Allergy and Clinical Immunology, ISSN: 00916749

Stephen Holgate; Thomas B. Casale; Sally E. Wenzel; Jean Bousquet; Yamo Deniz; Colin Reisner

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January 1, 2005

Alteplase stability and bioactivity after low-power ultrasonic energy delivery with the OmniSonics resolution system

Journal of Vascular and Interventional Radiology, ISSN: 10510443

John Smikahl; Yeung; Sharon Wang; Charles P. Semba

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January 1, 2005

Alteplase as a catheter locking solution: In vitro evaluation of biochemical stability and antimicrobial properties

Journal of Vascular and Interventional Radiology, ISSN: 10510443

Weck; Samantha Cheung; Hiraoka-Sutow; Thomas W. Patapoff; Charles P. Semba

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January 1, 2005

Proteomic profiling of recombinant Escherichia coli in high-cell-density fermentations for improved production of an antibody fragment biopharmaceutical

Applied and Environmental Microbiology, ISSN: 00992240

Ilana S. Aldor; Denise C. Krawitz; William F. Forrest; Christina Y. Chen; Julie C. Nishihara; John C. Joly; Kathleen M. Champion

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January 1, 2005

Adjuvant and neoadjuvant therapy in non-small cell lung cancer

Seminars in Oncology, ISSN: 00937754

Chandra P. Belani

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January 1, 2005

Epidemiology of cystic fibrosis-related diabetes

Journal of Pediatrics, ISSN: 00223476

Marshall; Butler; Stoddard; Moran; Liou; Morgan; Seema Asthana

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January 1, 2005

Met activation and receptor dimerization in cancer: A role for the Sema domain

Cell Cycle, ISSN: 15514005 15384101

Dineli Wickramasinghe; Monica Kong-Beltran

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January 1, 2005

Depletion of B cells by a humanized anti-CD20 antibody PRO70769 in Macaca Fascicularis

Journal of Immunotherapy, ISSN: 15249557

Yulia Vugmeyster; Joseph Beyer; Howell; Dan Combs; Fielder; Yang; Ferhan Qureshi; Bryan Sandlund; Ly Kawaguchi; Wolfgang Dummer; Henry B. Lowman; Kathleen McKeever

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January 1, 2005

Maximum tolerated dose of a humanized anti-vascular endothelial growth factor antibody fragment for treating neovascular age-related macular degeneration

Ophthalmology, ISSN: 01616420

Philip J. Rosenfeld; Steven D. Schwartz; Mark S. Blumenkranz; Joan W. Miller; Julia A. Haller; Reimann; William L. Greene; Naveed Shams

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