Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10801 - 10850 OF 15583 RESULTS

Uniform overexpression and rapid accessibility of α5β 1 integrin on blood vessels in tumors
American Journal of Pathology, ISSN: 00029440
Patricia Parsons-Wingerter; Ian Kasman; Scott Norberg; Anette Magnussen; Sara Zanivan; Alberto Rissone; Peter Baluk; Cecile J. Favre; Ursula Jeffry; Richard Murray; Donald M. McDonald
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A brief review of the use and utility of growth hormone stimulation testing in the NCGS: Do we need to do provocative GH testing?
Growth Hormone and IGF Research, ISSN: 15322238 10966374
Wilson; James W. Frane
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Single-molecule studies of synaptotagmin and complexin binding to the SNARE complex
Biophysical Journal, ISSN: 00063495
Mark E. Bowen; Keith Weninger; James A. Ernst; Steven Chu; Axel T. Brünger
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Development of a quantifiable symptom assessment tool for patients with chronic bronchitis: The Chronic Bronchitis Symptoms Assessment Scale
COPD: Journal of Chronic Obstructive Pulmonary Disease, ISSN: 15412563 15412555
David H. Au; David Blough; Leonard Kirchdoerfer; Kevin B.. Weiss; Edmunds M. Udris; Sean D. Sullivan
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Arming antibodies for cancer therapy
Current Opinion in Pharmacology, ISSN: 14714892
Paul G. Polakis
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Incidence of infection during efalizumab therapy for psoriasis: Analysis of the clinical trial experience
Clinical Therapeutics, ISSN: 1879114X 01492918
Richard G. B. Langley; Wayne Carey; Elyse S. Rafal; Stephen K. Tyring; Ivor Caro; Xiaolin Wang; Graham Wetherill; Kenneth B. Gordon
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PDA Technical Report No. 42: Process validation of protein manufacturing
PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440
Chris Bussineau; Robert Seely; Genevieve Lovitt; James Fernandez; Gregory S. Blank; Brandreth; Doris Conrad; Rebecca A. Devine; Robert J. Ferris; Koen De Heyder; Robert W. Juffras; Peter Levy; Wolfgang List; Morten Munk; Brian C. Neely; Stephen Notarnicola; O'Leary; Harold Van Deinse
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Good research practices for cost-effectiveness analysis alongside clinical trials: The ISPOR RCT-CEA Task Force report
Value in Health, ISSN: 10983015
Scott D. Ramsey; Richard Willke; Andrew Briggs; Ruth Brown; Martin Buxton; Chawla; John Cook; Henry Glick; Bengt Liljas; Diana Petitti; Shelby Reed
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Hormone receptor status does not affect the clinical benefit of trastuzumab therapy for patients with metastatic breast cancer
Clinical Breast Cancer, ISSN: 15268209
Adam Brufsky; Barry Lembersky; Kathy Schiffman; Lieberman; Virginia Paton
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Total serum IgE levels in a large cohort of patients with severe or difficult-to-treat asthma
Annals of Allergy, Asthma and Immunology, ISSN: 10811206
Larry Borish; Bradley E. Chipps; Yamo Deniz; Gujrathi; Zheng; Chantal M. Dolan
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Reversible self-association increases the viscosity of a concentrated monoclonal antibody in aqueous solution
Journal of Pharmaceutical Sciences, ISSN: 00223549
Jun Liu; Mary D. H. Nguyen; Andya; Steven J. Shire
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Capillary electrophoresis of carbohydrates derivatized with fluorophoric compounds.
Methods in Molecular Biology, ISSN: 10643745
Stacey Ma; Wendy Lau; Rodney Keck; Briggs; Andrew J.S. Jones; Kathy Moorhouse; Wassim Nashabeh
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Oligosaccharide release and MALDI-TOF MS analysis of N-linked carbohydrate structures from glycoproteins.
Methods in Molecular Biology, ISSN: 10643745
Rodney Keck; Briggs; Andrew J.S. Jones
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Regeneration of the adult central nervous system.
Current Biology, ISSN: 09609822
Lauren C Case; Marc Tessier-Lavigne
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Cancer risk in asthmatic populations
Annals of Allergy, Asthma and Immunology, ISSN: 10811206
Patricia Tennis; Beth Sherrill; Carlos Fernandez; Chantal M. Dolan
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Development and validation of the cystic fibrosis questionnaire in the United States: A health-related quality-of-life measure for cystic fibrosis
Chest, ISSN: 00123692
Alexandra L. Quittner; Anne Buu; Melissa A. Messer; Avani C. Modi; Marc Watrous
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Isolated central nervous system metastases in patients with HER2-overexpressing advanced breast cancer treated with first-line trastuzumab-based therapy
Annals of Oncology, ISSN: 15698041 09237534
Burstein; Lieberman; Dennis J. Slamon; Eric P. Winer; Pam Klein
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Vascular endothelial growth factor expression in the retinal pigment epithelium is essential for choriocapillaris development and visual function
American Journal of Pathology, ISSN: 00029440
Alexander G. Marneros; Jie Fan; Yoshihito Yokoyama; Hans-Peter Gerber; Napoleone Ferrara; Rosalie K. Crouch; Bjorn R. Olsen
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A role for Hath1, a bHLH transcription factor, in colon adenocarcinoma
Annals of the New York Academy of Sciences, ISSN: 00778923
Ching Ching Leow; Paul G. Polakis; Gao
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Influence of different hormonal regimens on endometrial microvascular density and VEGF expression in women suffering from breakthrough bleeding
Human Reproduction, ISSN: 14602350 02681161
Peter A.W. Rogers; Martinez; Girling; Lederman; Cann; Farrell; Tresserra; Patel
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Recombinant DNA Technology and Cell Line Development
Cell Culture Technology for Pharmaceutical and Cell-Based Therapies,
Amy Y. Shen; Jana Van de Goor; Lisa Zheng; Arthur Reyes; Lynne Krummen
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Activity-dependent internalization of smoothened mediated by β-Arrestin 2 and GRK2
Science, ISSN: 00368075
Wei Chen; Xiu-Rong Ren; Nelson; Larry S. Barak; James K. Chen; Philip A. Beachy; Frederic J. De Sauvage; Robert J. Lefkowitz
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Structural basis and therapeutic implication of the interaction of CCN proteins with glycoconjugates
Current Pharmaceutical Design, ISSN: 13816128
Luc Desnoyers
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Elimination of hepatic metastases of colon cancer cells via p53-independent cross-talk between irinotecan and Apo2 ligand/TRAIL
Cancer Research, ISSN: 00085472
Rajani Ravi; Ajay J. Jain; Richard D. Schulick; Vui Pham; Traci S. Prouser; Heather Allen; Elizabeth Garrett Mayer; Hua Yu; Drew M. Pardoll; Avi Ashkenazi; Atul Bedi
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Integrin α4β1 function is required for cell survival in developing retina
Developmental Biology, ISSN: 00121606
Sergiu T. Leu; Susan A.L. Jacques; Kevin L. Wingerd; Sherry T. Hikita; Erin C. Tolhurst; Jan L. Pring; Derek Wiswell; Lisa Kinney; Nichol L. Goodman; Jackson; Dennis O. Clegg
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IL-27 signaling compromises control of bacterial growth in mycobacteria-infected mice
Journal of Immunology, ISSN: 00221767
John E. Pearl; Shabaana A. Khader; Alejandra Solache; Leigh Gilmartin; Nico Ghilardi; Frederic J. De Sauvage; Andrea M. Cooper
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Roles of active site tryptophans in substrate binding and catalysis by α-1,3 galactosyltransferase
Glycobiology, ISSN: 09596658
Yingnan Zhang; Ashlesha Deshpande; Zhihong Xie; Ramanathan Natesh; K. Ravi Acharya; Keith Brew
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Randomized phase II trial comparing bevacizumab plus carboplatin and paclitaxel with carboplatin and paclitaxel alone in previously untreated locally advanced or metastatic non-small-cell lung cancer
Journal of Clinical Oncology, ISSN: 0732183X
David H. Johnson; Louis Fehrenbacher; Novotny; Roy S. Herbst; John J. Nemunaitis; David M. Jablons; Corey Langer; Russell F. DeVore III; Jacques Gaudreault; Lisa A. Damico; Holmgren; Fairooz F. Kabbinavar
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Biological activity of bevacizumab, a humanized anti-VEGF antibody in vitro
Angiogenesis, ISSN: 09696970
Yaning Wang; David T.W. Fei; Vanderlaan; An Song
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Competency-based benchmarking: Revolutionizing biopharmaceutical product launches
Benchmarking, ISSN: 14635771
Mark J. Ahn; Daniel Dornbusch
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Endocytosis and sorting of ErbB2 and the site of action of cancer therapeutics trastuzumab and geldanamycin
Molecular Biology of the Cell, ISSN: 10591524
Cary D. Austin; Ann De Mazière; Paul Pisacane; Suzanne Van Dijk; Eigenbrot; Mark X. Sliwkowski; Judith Klumperman; Richard H. Scheller
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The endo-lysosomal sorting machinery interacts with the intermediate filament cytoskeleton
Molecular Biology of the Cell, ISSN: 10591524
Melanie L. Styers; Gloria Salazar; Rachal Love; Andrew A. Peden; Andrew P. Kowalczyk; Victor Faundez
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The burden of illness associated with psoriasis: Cost of treatment with systemic therapy and phototherapy in the US
Current Medical Research and Opinion, ISSN: 03007995
William H. Crown; Bresnahan; Lucinda S. Orsini; Sean Kennedy; Craig Leonardi
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Development of a PCR method for mycoplasma testing of Chinese hamster ovary cell cultures used in the manufacture of recombinant therapeutic proteins
Biologicals, ISSN: 10451056
Joyce A. Eldering; Chantal Felten; Connie A. Veilleux; Barbara J. Potts
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Safety of treatment of metastatic breast cancer with trastuzumab beyond disease progression
Journal of Clinical Oncology, ISSN: 0732183X
Debasish Tripathy; Dennis J. Slamon; Melody A. Cobleigh; Andrew Arnold; Mansoor Saleh; Joanne E. Mortimer; Maureen Murphy; Stanford J. Stewart
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Transcriptional-based screens for pathway-specific, high-throughput target discovery in endothelial cells
Journal of Biomolecular Screening, ISSN: 10870571
Robert Yauch; Edward E. Kadel III; Cory Nicholas; Selwyna Tetangco; Douglas O. Clary
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Effect of anti-TGF-Β antibodies in syngeneic mouse models of metastasis
Journal of Musculoskeletal Neuronal Interactions, ISSN: 11087161
Richard A. D. Carano; Li; Bao; Li; Berry; Ross; Joe Kowalski; French; Dugger; Ralph H. Schwall; Wang; David T.W. Fei; Sarah L. Moseley; Ellen H. Filvaroff
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Visualization tool for a terrain-based genetic algorithm
Proceedings - International Conference on Tools with Artificial Intelligence, ICTAI, ISSN: 10823409
V. Scott Gordon; James Thein
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Elevated Flk1 (vascular endothelial growth factor receptor 2) signaling mediates enhanced angiogenesis in β3-integrin-deficient mice
Cancer Research, ISSN: 00085472
Andrew R. Reynolds; Louise E. Reynolds; Tobi Nagel; Julie C. Lively; Stephen D. Robinson; Daniel J. Hicklin; Bodary; Kairbaan M. Hodivala-Dilke
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Evaluation of a surrogate antibody for preclinical safety testing of an anti-CD11a monoclonal antibody
Regulatory Toxicology and Pharmacology, ISSN: 02732300
Janet Clarke; Will Leach; Susanne Pippig; Amita Joshi; Benjamin Wu; Robert House; Joseph Beyer
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Bv8 and endocrine gland-derived vascular endothelial growth factor stimulate hematopoiesis and hematopoietic cell mobilization
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Jennifer Lecouter; Constance Zlot; Max L. Tejada; Franklin V. Peale Jr.; Napoleone Ferrara
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Impurity effects on the crystallization kinetics of ampicillin
Industrial and Engineering Chemistry Research, ISSN: 08885885
Ottens; Lebreton; Zomerdijk; Rijkers; Bruinsma; Van Der Wielen
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Distinct ADAM metalloproteinases regulate G protein-coupled receptor-induced cell proliferation and survival
Journal of Biological Chemistry, ISSN: 00219258
Beatrix Schäfer; Beatrice Marg; Andreas Gschwind; Axel Ullrich
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The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system
Nature, ISSN: 00280836
Xiaowel Lu; Ferdinand Le Noble; Li Yuan; Quingjan Jiang; Benjamin De Lafarge; Daisuke Sugiyama; Christiane Bréant; Filip Claes; Frederik De Smet; Jean-Léon Thomas; Monica Autiero; Peter Carmeliet; Marc Tessier-Lavigne; Anne Eichmann
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The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity
Journal of Immunology, ISSN: 00221767
David Artis; Alejandro V. Villarino; Michael Silverman; Weimian He; Elizabeth M. Thornton; Sharon Mu; Shamin Summer; Todd M. Covey; Elaine Huang; Hiroki Yoshida; Gary Koretzky; Michael Goldschmidt; Gary D. Wu; Frederic J. De Sauvage; Hugh R. P. Miller; Christiaan J. M. Saris; Phillip Scott; Christopher A. Hunter
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Current immunomodulatory therapies for multiple sclerosis
Formulary, ISSN: 1082801X
Craig H. Smith
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Pharmacokinetics of novel dipeptide ester prodrugs of acyclovir after oral administration: Intestinal absorption and liver metabolism
Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565
Banmeet S. Anand; Suresh Katragadda; Ashim K. Mitra
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Simple quantitative live cell and anti-idiotypic antibody based ELISA for humanized antibody directed to cell surface protein CD20
Journal of Immunological Methods, ISSN: 00221759
Kyu Hong; Presta; Yanmei Lu; Ashley Penn; Adams; Anan Chuntharapai; Yang; Wai Lee T. Wong; Meng
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Efficacy of PUVA phototherapy compared with biologics
Cosmetic Dermatology, ISSN: 10413766
John Y. Koo; Rachel Wenner
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Interferon regulatory factor 1 binding to p300 stimulates DNA-dependent acetylation of p53
Molecular and Cellular Biology, ISSN: 02707306
David Dornan; Mirjam Eckert; Maura Wallace; Harumi Shimizu; Eleanor Ramsay; Ted R. Hupp; Kathryn L. Ball
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