Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10851 - 10900 OF 15583 RESULTS

A new suite of automated bioreactors at Genentech: A case study employing standards, guidelines, and software: From requirements to validation
Pharmaceutical Engineering, ISSN: 02738139
Ronald E. Menéndez
View on Scopus
Novel biologic agents for multiple sclerosis and their impact on managed care
Formulary, ISSN: 1082801X
Schumarry H. Chao; Craig H. Smith
View on Scopus
The effect of drotrecogin alfa (activated) on long-term survival after severe sepsis
Critical Care Medicine, ISSN: 00903493
Derek C. Angus; Pierre-Francois Laterre; Jeffrey D. Helterbrand; E. Wesley Ely; Daniel E. Ball; Rekha Garg; Lisa A. Weissfeld; Gordon R. Bernard
View on Scopus
Detection and in vitro and in vivo characterization of porcine circovirus DNA from a porcine-derived commercial pepsin product
Journal of General Virology, ISSN: 00221317
Fenaux; Opriessnig; Halbur; Yuan Xu; Barbara J. Potts; Meng
View on Scopus
Tissue distribution, stability, and pharmacokinetics of APO2 ligand/tumor necrosis factor-related apoptosis-inducing ligand in human colon carcinoma COLO205 tumor-bearing nude mice
Drug Metabolism and Disposition, ISSN: 00909556
Hong Xiang; Cindy B. Nguyen; Kelley; Noel Dybdal; Escandon
View on Scopus
Vascular endothelial growth factor-induced nitric oxide-and PGI 2-dependent relaxation in human internal mammary arteries: A comparative study with KDR and Flt-1 selective mutants
Journal of Cardiovascular Pharmacology, ISSN: 01602446
Wei Wei; Hongkui Jin; Zhi-Wu Chen; Zioncheck; Anthony P. C. Yim; Guo-Wei He
View on Scopus
Early withdrawal of statin therapy in patients with non-ST-segment elevation myocardial infarction: National registry of myocardial infarction
Archives of Internal Medicine, ISSN: 00039926
Frederick A. Spencer; Gregg C. Fonarow; Paul D. Frederick; R. Scott Wright; Nathan R. Every; Robert J. Goldberg; Joel M. Gore; Wei Dong; Richard C. Becker; William J. French
View on Scopus
Angiogenesis-dependent and independent phases of intimal hyperplasia
Circulation, ISSN: 00097322
Rohit Khurana; Zhenwu Zhuang; Shalini Bhardwaj; Masahiro Murakami; Ebo De Muinck; Seppo Yla-Herttuala; Napoleone Ferrara; John F. Martin; Ian Zachary; Michael Simons
View on Scopus
COP1, the negative regulator of p53, is overexpressed in breast and ovarian adenocarcinomas
Cancer Research, ISSN: 00085472
David Dornan; Sheila Bheddah; Kim Newton; William Inice; Gretchen D. Frantz; Patrick Dowd; Koeppen; Vishva M. Dixit; French
View on Scopus
The crystal structure of A proliferation-inducing ligand, APRIL
Journal of Molecular Biology, ISSN: 00222836
Heidi J. A. Wallweber; Deanne M. Compaan; Melissa A. Starovasnik; Sarah G. Hymowitz
View on Scopus
Bevacizumab in colorectal cancer [2] (multiple letters)
New England Journal of Medicine, ISSN: 00284793
Guru Sonpavde; Waseem Sharieff; Herbert Hurwitz; Novotny; Fairooz F. Kabbinavar
View on Scopus
Differential requirements for semaphorin 3F and slit-1 in axonal targeting, fasciculation, and segregation of olfactory sensory neuron projections
Journal of Neuroscience, ISSN: 02706474
Jean-François Cloutier; Amar Sahay; Ernie C. Chang; Marc Tessier-Lavigne; Catherine Dulac; Alex L. Kolodkin; David D. Ginty
View on Scopus
GEPIS - Quantitative gene expression profiling in normal and cancer tissues
Bioinformatics, ISSN: 13674803
Yan Zhang; Eberhard; Gretchen D. Frantz; Patrick Dowd; Thomas D Wu; Yan Zhou; Colin K. Watanabe; Shiuh-Ming Luoh; Paul G. Polakis; Kenneth J. Hillan; William I. Wood; Zemin Zhang
View on Scopus
Racial and ethnic differences in time to acute reperfusion therapy for patients hospitalized with myocardial infarction
JAMA - Journal of the American Medical Association, ISSN: 00987484
Elizabeth H. Bradley; Jeph Herrin; Yongfei Wang; Robert L. McNamara; Tashonna R. Webster; David J. Magid; Martha Blaney; Eric D. Peterson; John G. Canto; Charles V. Pollack Jr.; Harlan M. Krumholz
View on Scopus
Selective impairment of TLR-mediated innate immunity in human newborns: Neonatal blood plasma reduces monocyte TNF-α induction by bacterial lipopeptides, lipopolysaccharide, and imiquimod, but preserves the response to R-848
Journal of Immunology, ISSN: 00221767
Ofer Levy; Kol A. Zarember; Rene M. Roy; Colette Cywes; Godowski; Michael R. Wessels
View on Scopus
Quantification of cortical bone loss and repair for therapeutic evaluation in collagen-induced arthritis, by micro-computed tomography and automated image analysis
Arthritis and Rheumatism, ISSN: 00043591
Kai H. Barck; Wyne P. Lee; Laurie Diehl; Ross; Gribling; Yifan Zhang; Kathy Nguyen; Nicholas Van Bruggen; Stephen D. Hurst; Richard A. D. Carano
View on Scopus
Effect of long-term progestin treatment on endometrial vasculature in normal cycling mice
Contraception, ISSN: 00107824
Girling; Heryanto; Patel; Peter A.W. Rogers
View on Scopus
Capillary regression in vascular endothelial growth factor-deficient skeletal muscle
Physiological Genomics, ISSN: 15312267
Kechun Tang; Ellen C. Breen; Hans-Peter Gerber; Napoleone Ferrara; Peter D. Wagner
View on Scopus
Protein-protein interactions governing septin heteropentamer assembly and septin filament organization in Saccharomyces cerevisiae
Molecular Biology of the Cell, ISSN: 10591524
Matthias Versele; Björn Gullbrand; Shulewitz; Victor J. Cid; Shirin Bahmanyar; Raymond E. Chen; Patrick Barth; Tom Alber; Jeremy Thorner
View on Scopus
A pH-sensitive function and phenotype: Evidence that EutH facilitates diffusion of uncharged ethanolamine in Salmonella enterica
Journal of Bacteriology, ISSN: 00219193
Joseph T. Penrod; Christopher C. Mace; John R. Roth
View on Scopus
Suppressor of fused regulates Gli activity through a dual binding mechanism
Molecular and Cellular Biology, ISSN: 02707306
Mark Merchant; Vajdos; Ultsch; Henry R. Maun; K. Ulrich Wendt; Jennifer Cannon; William Desmarais; Lazarus; De Vos; Frederic J. De Sauvage
View on Scopus
Phase I trial of irinotecan, infusional 5-fluorouracil, and leucovorin (FOLFIRI) with erlotinib (OSI-774): Early termination due to increased toxicities
Clinical Cancer Research, ISSN: 10780432
Wells A. Messersmith; Daniel A. Laheru; Neil N. Senzer; Ross C. Donehower; Paula Grouleff; Theresa Rogers; Kelley; David A. Ramies; Bert L. Lum; Manuel Hidalgo
View on Scopus
Signal peptide prediction based on analysis of experimentally verified cleavage sites
Protein Science, ISSN: 09618368
Zemin Zhang; William J. Henzel
View on Scopus
Production technologies for monoclonal antibodies and their fragments
Current Opinion in Biotechnology, ISSN: 09581669
Dana C. Andersen; Dorothea Reilly
View on Scopus
Efalizumab (anti-CD11a)-induced increase in peripheral blood leukocytes in psoriasis patients is preferentially mediated by altered trafficking of memory CD8+ T cells into lesional skin
Clinical Immunology, ISSN: 15216616
Yulia Vugmeyster; Toyoko Kikuchi; Michelle A. Lowes; Francesca Chamian; Mark Kagen; Patricia Gilleaudeau; Edmund Lee; Howell; Bodary; Wolfgang Dummer; James G. Krueger
View on Scopus
Real time quantitative PCR as a method to evaluate xenotropic murine leukemia virus removal during pharmaceutical protein purification
Biotechnology and Bioengineering, ISSN: 00063592
Shi; Qi Chen; Lenore A Norling; Allen S.L. Lau; Sherrie Krejci; Yuan Xu
View on Scopus
Structural and functional basis of the serine protease-like hepatocyte growth factor β-chain in met binding and signaling
Journal of Biological Chemistry, ISSN: 00219258
Daniel Kirchhofer; Xiaoyi Yao; Peek; Eigenbrot; Michael T. Lipari; Karen L Billeci; Henry R. Maun; Paul Moran; Santell; Wiesmann; Lazarus
View on Scopus
Bioinformatics and cancer target discovery
Drug Discovery Today, ISSN: 13596446
Brian Desany; Zemin Zhang
View on Scopus
The mouse frizzled 8 receptor is expressed in anterior organizer tissues
Gene Expression Patterns, ISSN: 1567133X
Lu; Elizabeth J. Robertson; Jane Brennan
View on Scopus
Barriers to biologics
Cutis, ISSN: 00114162
Jeffrey M. Weinberg
View on Scopus
The Caenorhabditis elegans nuclear receptor gene nhr-25 regulates epidermal cell development
Molecular and Cellular Biology, ISSN: 02707306
Zhe Chen; Dennis J. Eastburn; Min Han
View on Scopus
Clinical benefits in patients with psoriasis after efalizumab therapy: Clinical trials versus practice
Cutis, ISSN: 00114162
Roberto R. Ricardo; Matthe Rhoa; Elaine K. Orenberg; Nicole F. Li; Amy Chen Rundle; Ivor Caro
View on Scopus
Caspase-8 serves both apoptotic and nonapoptotic roles
Journal of Immunology, ISSN: 00221767
Tae-Bong Kang; Tehila Ben-Moshe; Eugene Varfolomeev; Yael Pewzner-Jung; Nir Yogev; Anna Jurewicz; Ari Waisman; Ori Brenner; Rebecca Haffner; Erika Gustafsson; Parameswaran Ramakrishnan; Tsvee Lapidot; David Wallach
View on Scopus
Hath1, down-regulated in colon adenocarcinomas, inhibits proliferation and tumorigenesis of colon cancer cells
Cancer Research, ISSN: 00085472
Ching Ching Leow; Maria Romero; Ross; Paul G. Polakis; Gao
View on Scopus
Activation of caspases-8 and -10 by FLIPL
Biochemical Journal, ISSN: 02646021
Kelly M. Boatright; Cristina Deis; Jean-Bernard Denault; Daniel P. Sutherlin; Guy S. Salvesen
View on Scopus
Receptor-mediated basic fibroblast growth factor signaling regulates cyclic pressure-induced human endothelial cell proliferation
Endothelium: Journal of Endothelial Cell Research, ISSN: 10623329
Hainsworth Y. Shin; Eric A. Schwartz; Rena Bizios; Mary E. Gerritsen
View on Scopus
In vitro internalization, intracellular transport, and clearance of an anti-CD11a antibody (Raptiva) by human T-cells
Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565
Greg P. Coffey; Stefanich; Susan Palmieri; Eckert; Josette Padilla-Eagar; Fielder; Susanne Pippig
View on Scopus
B-cell subsets in blood and lymphoid organs in Macaca fascicularis
Cytometry Part A, ISSN: 15524922
Yulia Vugmeyster; Howell; Anahid Bakshi; Flores; Hwang; Kathleen McKeever
View on Scopus
Synthetic antibodies from a four-amino-acid code: A dominant role for tyrosine in antigen recognition
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Frederic A. Fellouse; Wiesmann; Sachdev S. Sidhu
View on Scopus
Hybrid photoactive assemblies: Electron injection from host-guest complexes into semiconductor nanoparticles
Journal of the American Chemical Society, ISSN: 00027863
Cynthia Pagba; Giovanni Zordan; Elena Galoppini; Evgueni L. Piatnitski; Sarmimala Hore; Deshayes; Piotrowiak
View on Scopus
Activation and substrate specificity of caspase-14
Biochemistry, ISSN: 00062960
Jowita Mikolajczyk; Fiona L. Scott; Stan Krajewski; Daniel P. Sutherlin; Guy S. Salvesen
View on Scopus
Cuttin edge: Differential roles for phosphoinositide 3-kinases, p110γ and p110δ, lymphocyte chemotaxis and homing
Journal of Immunology, ISSN: 00221767
Karin Reif; Klaus Okkenhaug; Takehiko Sasaki; Josef Penninger; Bart Vanhaesebroeck; Jason G. Cyster
View on Scopus
Caspase-2 can function upstream of bid cleavage in the TRAIL apoptosis pathway
Journal of Biological Chemistry, ISSN: 00219258
Klaus W. Wagner; Ingo H. Engels; Quinn L. Deveraux
View on Scopus
The therapeutic potential of hepatocyte growth factor for myocardial infarction and heart failure
Current Pharmaceutical Design, ISSN: 13816128
Hongkui Jin; Wyss; Renhui Yang; Ralph H. Schwall
View on Scopus
Molecular characterization of Rab11 interactions with members of the family of Rab11-interacting proteins
Journal of Biological Chemistry, ISSN: 00219258
Jagath R. Junutula; Eric Schonteich; Gayle M. Wilson; Andrew A. Peden; Richard H. Scheller; Rytis Prekeris
View on Scopus
De-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-κB signalling
Nature, ISSN: 00280836
Ingrid E. Wartz; Karen M. O'Rourke; Honglin Zhou; Mike Eby; Aravind; Somasekar Seshagiri; Ping Wu; Wiesmann; Rohan Baker; David L. Boone; Averil Ma; Eugene V. Koonin; Vishva M. Dixit
View on Scopus
Purification of antibody and antibody-fragment from E. coli homogenate using 6,9-diamino-2-ethoxyacridine lactate as precipitation agent
Biotechnology and Bioengineering, ISSN: 00063592
Josefine Persson; Philip M. Lester
View on Scopus
Human endocrine gland-derived vascular endothelial growth factor: Expression early in development and in Leydig cell tumors suggests roles in normal and pathological testis angiogenesis
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Michel Samson; Franklin V. Peale Jr.; Gretchen D. Frantz; Nathalie Rioux-Leclercq; Ewa Rajpert-De Meyts; Napoleone Ferrara
View on Scopus
Pharmacodynamics of telavancin (TD-6424), a novel bactericidal agent, against gram-positive bacteria
Antimicrobial Agents and Chemotherapy, ISSN: 00664804
Sharath S. Hegde; Noe Reyes; Tania Wiens; Nicole Vanasse; Robert Skinner; Julia McCullough; Koné Kaniga; John Pace; Roger Thomas; Jeng-Pyng Shaw; Glen Obedencio; J. Kevin Judice
View on Scopus
Human IgE response to the Schistosoma haematobium 22.6 kDa antigen
Parasite Immunology, ISSN: 01419838
Fitzsimmons; Stewart; Karl F. Hoffmann; Jane L. Grogan; Maria Yazdanbakhsh; David W. Dunne
View on Scopus
© 2025 Genentech, Inc. All rights reserved. This site is intended for US residents only.