Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10901 - 10950 OF 15583 RESULTS

Rituximab-mediated depletion of cynomolgus monkey B cells in vitro in different matrices: Possible inhibitory effect of IgG
International Immunopharmacology, ISSN: 15675769
Yulia Vugmeyster; Howell
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The RCP-Rab11 complex regulates endocytic protein sorting
Molecular Biology of the Cell, ISSN: 10591524
Andrew A. Peden; Eric Schonteich; John Chun; Jagath R. Junutula; Richard H. Scheller; Rytis Prekeris
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BMP signaling initiates a neural crest differentiation program in embryonic rat CNS stem cells
Experimental Neurology, ISSN: 00144886
Shyam Gajavelli; Patrick M. Wood; Diane Pennica; Scott R. Whittemore; Tsoulfas
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Comparing total health care costs and treatment patterns of HIV patients in a managed care setting
AIDS Care - Psychological and Socio-Medical Aspects of AIDS/HIV, ISSN: 09540121
Purdum; Johnson; Globe
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Expression of vascular endothelial growth factor receptor-3 by lymphatic endothelial cells is associated with lymph node metastasis in prostate cancer
Clinical Cancer Research, ISSN: 10780432
Yiping Zeng; Kenneth Opeskin; Megan E. Baldwin; Lisa G. Horvath; Marc G. Achen; Steven A. Stacker; Robert L. Sutherland; Elizabeth D. Williams
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Allosteric inhibition of protein tyrosine phosphatase 1B
Nature Structural and Molecular Biology, ISSN: 15459993
Wiesmann; Kenneth J. Barr; Jenny Kung; Jiang Zhu; Daniel A. Erlanson; Wang Shen; Bruce J. Fahr; Min Zhong; Lisa Taylor; Mike Randall; Robert S. McDowell; Stig K. Hansen
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Vascular endothelial growth factor: Basic science and clinical progress
Endocrine Reviews, ISSN: 0163769X
Napoleone Ferrara
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Evolution and divergence of the genes for cytoplasmic, mitochondrial, and flagellar creatine kinases
Journal of Molecular Evolution, ISSN: 00222844
Tomohiko Suzuki; Chisa Mizuta; Kouji Uda; Keiko Ishida; Kanae Mizuta; Sona Sona; Deanne M. Compaan; W. Ross Ellington
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Efficacy and safety of two unfractionated heparin dosing strategies with Tenecteplase in acute myocardial infarction (results from Assessment of the Safety and Efficacy of a New Thrombolytic Regimens 2 and 3)
American Journal of Cardiology, ISSN: 00029149
Jeptha P. Curtis; John H. Alexander; Yao Huang; Lars Wallentin; Verheugt; Paul W. Armstrong; Harlan M. Krumholz; Frans Van De Werf; Danays; Morris Cheeks; Christopher B. Granger
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A Substrate-phage approach for investigating caspase specificity
Protein Journal, ISSN: 15723887
Samantha Lien; Richard Pastor; Daniel P. Sutherlin; Henry B. Lowman
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High-affinity human antibodies from phage-displayed synthetic Fab libraries with a single framework scaffold
Journal of Molecular Biology, ISSN: 00222836
Chingwei V. Lee; Wei-Ching Liang; Dennis; Eigenbrot; Sachdev S. Sidhu; Fuh
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VEGF-null cells require PDGFR α signaling-mediated stromal fibroblast recruitment for tumorigenesis
EMBO Journal, ISSN: 02614189
Jianying Dong; Jeremy Grunstein; Max L. Tejada; Franklin V. Peale Jr.; Gretchen D. Frantz; Wei-Ching Liang; Wei Bai; Lanlan Yu; Joe Kowalski; Xiao Huan Liang; Fuh; Hans-Peter Gerber; Napoleone Ferrara
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A novel in vivo role for osteoprotegerin ligand in activation of monocyte effector function and inflammatory response
Journal of Biological Chemistry, ISSN: 00219258
Dhaya Seshasayee; Hua Wang; Wyne P. Lee; Gribling; Ross; Nicholas Van Bruggen; Richard A. D. Carano; Iqbal S. Grewal
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Apo2 ligand/tumor necrosis factor-related apoptosis-inducing ligand cooperates with chemotherapy to inhibit orthotopic lung tumor growth and improve survival
Cancer Research, ISSN: 00085472
Hongkui Jin; Renhui Yang; Fong; Klara Totpal; David Lawrence; Zhong Zheng; Ross; Koeppen; Ralph H. Schwall; Avi Ashkenazi
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Comprehensive mutational analysis of the M13 major coat protein: Improved scaffolds for C-terminal phage display
Journal of Molecular Biology, ISSN: 00222836
Heike A. Held; Sachdev S. Sidhu
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Cardiotrophin-1 in choroid plexus and the cerebrospinal fluid circulatory system
Neuroscience, ISSN: 03064522
Gard; Gavin; Solodushko; Diane Pennica
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Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf
Nature, ISSN: 00280836
Sanjeev Mariathasan; Kim Hewton; Denise M. Monack; Domagoj Vucic; French; Wyne P. Lee; Merone Roose-Girma; Sharon Erickson; Vishva M. Dixit
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Inhibition of netrin-mediated axon attraction by a receptor protein tyrosine phosphatase
Science, ISSN: 00368075
Chieh Chang; Timothy W. Yu; Cornelia I. Bargmann; Marc Tessier-Lavigne
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Down syndrome critical region protein 1 (DSCR1), a novel VEGF target gene that regulates expression of inflammatory markers on activated endothelial cells
Blood, ISSN: 00064971
Boris A. Hesser; Xiao Huan Liang; Camenisch; Suya Yang; Lewin; Richard Scheller; Napoleone Ferrara; Hans-Peter Gerber
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Circulating D-dimer levels are better predictors of overall survival and disease progression than carcinoembryonic antigen levels in patients with metastatic colorectal carcinoma
Cancer, ISSN: 0008543X
Kimberly Blackwell; Herbert Hurwitz; Lieberman; Novotny; Stacey Snyder; Mark Dewhirst; Charles Greenberg
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PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates
Nature, ISSN: 00280836
Lu; Annete G. M. Borchers; Christine Jolicoeur; Helen Rayburn; Julie C. Baker; Marc Tessier-Lavigne
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Pharmacokinetic and pharmacodynamic characteristics of a long-acting Growth Hormone (GH) preparation (nutropin depot) in GH-deficient children
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Stephen F. Kemp; Fielder; Kenneth M. Attie; Sandra L. Blethen; Edward O. Reiter; Kathleen M. Ford; Marian; Dao; Lee; Saenger
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The Risk Score Profile: A novel approach to characterising the risk of populations enrolled in clinical studies
European Heart Journal, ISSN: 0195668X
David A. Morrow; Elliott M. Antman; Sabina A. Murphy; Susan F. Assmann; Robert P. Giugliano; Christopher P. Cannon; C.Michael Gibson; Carolyn H. McCabe; Hal V. Barron; Frans Van De Werf; Eugene Braunwald
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Decrease in tumor apparent permeability-surface area product to a MRI macromolecular contrast medium following angiogenesis inhibition with correlations to cytotoxic drug accumulation
Microcirculation, ISSN: 10739688
Heike E. Daldrup-Link; Yoshitaka Okuhata; Allan Wolfe; Sudesk Srivastav; Sven Øie; Napoleone Ferrara; Robert L. Cohen; David M. Shames; Robert C. Brasch
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Relation of age and race with hospital death after acute myocardial infarction
American Heart Journal, ISSN: 00028703
Ajay Manhapra; John G. Canto; Viola Vaccarino; Lori Parsons; Calarina I. Kiefe; Hal V. Barron; William J. Rogers; W.Douglas Weaver; Steven Borzak
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Convergent recognition of the IgE binding site on the high-affinity IgE receptor
Structure, ISSN: 09692126
Jennifer Stamos; Eigenbrot; Nakamura; Mark E. Reynolds; Jianping Yin; Henry B. Lowman; Wayne J. Fairbrother; Melissa A. Starovasnik
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Modifications and intracellular trafficking of FADD/MORT1 and caspase-8 after stimulation of T lymphocytes
Cell Death and Differentiation, ISSN: 13509047
O'Reilly; Divisekera; Kim Newton; Scalzo; Kataoka; Puthalakath; Ito; David C.S. Huang; Andreas Strasser
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Clinical targeting of VEGF and EGFR effective in non-small cell lung cancer
Cancer Biology and Therapy, ISSN: 15384047 15558576
Roy S. Herbst; Eric Mininberg; Ted Henderson; Edward S. Kim; George R. Blumenschein; J. Jack J. Lee; Mylene Truong; Waun Hong; David H. Johnson; David Carbone; Ben Garcia; Dong Xie; Kelley
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Targeting interferon-α: A promising approach for systemic lupus erythematosus therapy
Lupus, ISSN: 09612033
Kerstin N. Schmidt; Wenjun Ouyang
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Vascular endothelial growth factor as a target for anticancer therapy
Oncologist, ISSN: 10837159
Napoleone Ferrara
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Circulating humoral factors and endothelial progenitor cells in patients with differing coronary collateral support
Circulation, ISSN: 00097322
Pier D. Lambiase; Richard J. Edwards; Prodromos Anthopoulos; Salman Rahman; Meng; Clifford A. Bucknall; Simon R. Redwood; Jeremy D. Pearson; Marber
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T-cell modulation for the treatment of chronic plaque psoriasis with efalizumab (Raptiva™): Mechanisms of action
Dermatology, ISSN: 10188665
Jullien; Prinz; Richard G. B. Langley; Ivor Caro; Wolfgang Dummer; Amita Joshi; Russell L Dedrick; Natta
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Crystal structure of the HGF β-chain in complex with the Sema domain of the Met receptor
EMBO Journal, ISSN: 02614189
Jennifer Stamos; Lazarus; Xiaoyi Yao; Daniel Kirchhofer; Wiesmann
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Cost-effectiveness of testing for hypercoagulability and effects on treatment strategies in patients with deep vein thrombosis
American Journal of Medicine, ISSN: 00029343
Andrew D. Auerbach; Gillian D. Sanders; Julie Hambleton
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Gene expression profiling for prognosis using Cox regression
Statistics in Medicine, ISSN: 02776715
Yudi Pawitan; Bjöhle; Wedren; Humphreys; Skoog; Huang; Lukas Amler; Shaw; Hall; Bergh
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Flex test: A fluorescent dextran test for UF membrane characterization
Journal of Membrane Science, ISSN: 03767388
Poonam Mulherkar; Robert Van Reis
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An industry survey on current practices in the design and analysis of active control studies
Journal of Biopharmaceutical Statistics, ISSN: 10543406
Christy Chuang-Stein; Corsee Sanders; Steve Snapinn
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AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells
Journal of Biological Chemistry, ISSN: 00219258
Gloria Salazar; Rachal Love; Melanie L. Styers; Erica Werner; Andrew A. Peden; Sandra Rodriguez; Marla Gearing; Bruce H. Wainer; Victor Faundez
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Notch1-expressing cells are indispensable for prostatic branching morphogenesis during development and re-growth following castration and androgen replacement
Journal of Biological Chemistry, ISSN: 00219258
Xi-De Wang; Shou; Peter Wong; French; Gao
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Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
New England Journal of Medicine, ISSN: 00284793
Herbert Hurwitz; Louis Fehrenbacher; Novotny; Thomas Cartwright; John Hainsworth; William Heim; Jordan Berlin; Ari Baron; Susan Griffing; Holmgren; Napoleone Ferrara; Gwendolyn Fyfe; Rogers; Robert Ross; Fairooz F. Kabbinavar
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Creation and characterization of a mouse model of mandibular distraction osteogenesis
Bone, ISSN: 87563282
Tony D. Fang; Randall P. Nacamuli; Hanjoon M. Song; Kenton D. Fong; Stephen M. Warren; Ali Salim; Richard A. D. Carano; Ellen H. Filvaroff; Michael T. Longaker
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Oxidative and osmotic stress signaling in tumor cells is mediated by ADAM proteases and heparin-binding epidermal growth factor
Molecular and Cellular Biology, ISSN: 02707306
Oliver M. Fischer; Stefan Hart; Andreas Gschwind; Norbert Prenzel; Axel Ullrich
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Acute metabolic acidosis: Characterization and diagnosis of the disorder and the plasma potassium response
Journal of the American Society of Nephrology, ISSN: 10466673
Jean-Martin Wiederseiner; Juergen Muser; Thomas Lutz; Henry N. Hulter; Reto Krapf
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A public gene trap resource for mouse functional genomics [1]
Nature Genetics, ISSN: 10614036
William C. Skarnes; Harald Von Melchner; Wolfgang Wurst; Geoff Hicks; Alex S. Nord; Tony Cox; Stephen G. Young; Patricia Ruiz; Phil Soriano; Marc Tessier-Lavigne; Bruce R. Conklin; William L. Stanford; Janet Rossant
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Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes
Endocrinology, ISSN: 00137227
Ling Fu; Linu M. John; Adams; Yu; Elizabeth Tomlinson; Renz; P. Mickey Williams; Robert Soriano; Corpuz; Moffat; Richard L. Vandlen; Laura C. Simmons; Foster; Jean-Philippe Stephan; Siao Ping Tsai; Stewart
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Novel role for netrins in regulating epithelial behavior during lung branching morphogenesis
Current Biology, ISSN: 09609822
Yuru Liu; Elke Stein; Timothy Oliver; Yong Li; William J. Brunken; Manuel Koch; Marc Tessier-Lavigne; Brigid L.M. Hogan
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Pharmacy benefits and the use of drugs by the chronically ill
JAMA - Journal of the American Medical Association, ISSN: 00987484
Dana P. Goldman; Geoffrey F. Joyce; Jose J. Escarce; Jennifer E. Pace; Matthew D. Solomon; Marianne Laouri; Pamela B. Landsman; Steven M. Teutsch
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Identification of Wnt responsive genes using a murine mammary epithelial cell line model system
BMC Developmental Biology, ISSN: 1471213X
Lisa A. Taneyhill; Diane Pennica
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Thyrotropin-Releasing Hormone Is Induced in the Left Ventricle of Rats with Heart Failure and Can Provide Inotropic Support to the Failing Heart
Circulation, ISSN: 00097322
Hongkui Jin; Grazyna Fedorowicz; Renhui Yang; Annie Ogasawara; Franklin V. Peale Jr.; Thinh Q. Pham; Nicholas F. Paoni
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The Dorsolateral Corticospinal Tract in Mice: An Alternative Route for Corticospinal Input to Caudal Segments following Dorsal Column Lesions
Journal of Comparative Neurology, ISSN: 00219967
Oswald Steward; Binhai Zheng; Carole Ho; Kim Anderson; Marc Tessier-Lavigne
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