Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11801 - 11850 OF 15583 RESULTS

June 10, 2000

A phase II study of two HIV type 1 envelope vaccines, comparing their immunogenicity in populations at risk for acquiring HIV type 1 infection

AIDS Research and Human Retroviruses, ISSN: 08892229

M. Juliana McElrath; Lawrence Corey; David Montefiori; Mark Wolff; David Schwartz; Michael C. Keefer; Robert Belshe; Barney S. Graham; Matthews; Peter Wright; Geoffrey Gorse; Raphael Dolin; Berman; Francis; A-M. Duliege; Dani P. Bolognesi; Donald M. Stablein; Nzeera Ketter; Patricia Fast

June 6, 2000

Cockroach diuretic hormones: Characterization of a calcitonin-like peptide in insects

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Kenji Furuya; Richard J. Milchak; Kathleen M. Schegg; Jinrui Zhang; Stephen S. Tobe; Geoffrey M. Coast; David A. Schooley

June 5, 2000

VEGF nuclear accumulation correlates with phenotypical changes in endothelial cells

Journal of Cell Science, ISSN: 00219533

Wenlu Li; Gilbert-Andre Keller

June 1, 2000

Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI

Current Biology, ISSN: 09609822

Scot A. Marsters; Minhong Yan; Pitti; Philip E. Haas; Vishva M. Dixit; Avi Ashkenazi

June 1, 2000

Immunopolymerase chain reaction using real-time polymerase chain reaction for detection

Analytical Biochemistry, ISSN: 00032697

Paul Sims; Vasser; Wai Lee T. Wong; P. Mickey Williams; Meng

June 1, 2000

Variations on ligand-receptor complexes

Nature Structural Biology, ISSN: 10728368

Wiesmann; De Vos

June 1, 2000

ABRF-98SEQ: Evaluation of peptide sequencing at high sensitivity

Journal of Biomolecular Techniques, ISSN: 15240215 19434731

William J. Henzel; Arie Admon; Steve A. Carr; Gary Davis; Karen De Jongh; William Lane; Michael Rohd; Laurey Steinke

June 1, 2000

Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears

Nature Neuroscience, ISSN: 10976256

Zheng; Gao

May 25, 2000

The volume of primary angioplasty procedures and survival after acute myocardial infarction

New England Journal of Medicine, ISSN: 00284793

John G. Canto; Nathan R. Every; David J. Magid; William J. Rogers; Judith A. Malmgren; Paul D. Frederick; William J. French; Alan J. Tiefenbrunn; Vijay K. Misra; Calarina I. Kiefe; Hal V. Barron

May 16, 2000

Evidence for the involvement of histidine A(12) in the aggregation and precipitation of human relaxin induced by metal-catalyzed oxidation

Biochemistry, ISSN: 00062960

Mehrnaz Khossravi; Steven J. Shire; Ronald T. Borchardt

May 15, 2000

Radiation and the Apo2L/TRAIL apoptotic pathway preferentially inhibit the colonization of premalignant human breast cells overexpressing cyclin D1

Cancer Research, ISSN: 00085472

Qun Zhou; Paula Fukushima; William DeGraff; James B. Mitchell; Maryalice Stetler-Stevenson; Avi Ashkenazi; Patricia S. Steeg

May 15, 2000

Stability and interactions of recombinant human nerve growth factor in different biological matrices: In vitro and in vivo studies

Drug Metabolism and Disposition, ISSN: 00909556

Cindy B. Nguyen; Szonyi; Michael D Sadick; Hotaling; José-Luis Mendoza-Ramírez; Escandon

May 15, 2000

Tissue disposition and pharmacokinetics of recombinant human nerve growth factor after acute and chronic subcutaneous administration in monkeys

Drug Metabolism and Disposition, ISSN: 00909556

Cindy B. Nguyen; Louise A. Harris; Szonyi; Sharon A. Baughman; Victoria Hale; Noel Dybdal; Michael D Sadick; Escandon

May 15, 2000

Structural basis of the Axin-adenomatous polyposis coli interaction

EMBO Journal, ISSN: 02614189

Katharine Eklof Spink; Paul G. Polakis; William I. Weis

May 15, 2000

Pharmacokinetics, tissue distribution, metabolism, and excretion of celecoxib in rats

Drug Metabolism and Disposition, ISSN: 00909556

Susan K. Paulson; Ji Y. Zhang; Alan P. Breau; Jeremy D. Hribar; Norman W. K. Liu; Susan M. Jessen; Yvette M. Lawal; J. Nita Cogburn; Christopher J. Gresk; Charles S. Markos; Timothy J. Maziasz; Grant L. Schoenhard; Earl G. Burton

May 11, 2000

Growth factors: Formation of endothelial cell networks

Nature, ISSN: 00280836

Gabriel Helmlinger; Mitsuhiro Endo; Napoleone Ferrara; Lynn Hlatky; Rakesh K. Jain

May 2, 2000

Claims of equivalence in medical research: Are they supported by the evidence?

Annals of Internal Medicine, ISSN: 00034819

William L. Greene; John Concato; Alvan R. Feinstein

May 1, 2000

Heregulin, but not ErbB2 or ErbB3, heterozygous mutant mice exhibit hyperactivity in multiple behavioral tasks

Behavioural Brain Research, ISSN: 01664328

Gerlai; Paul Pisacane; Sharon Erickson

May 1, 2000

AIDSVAX® (MN) in Bangkok injecting drag users: A report on safety and immunogenicity, including macrophage-tropic virus neutralization

AIDS Research and Human Retroviruses, ISSN: 08892229

Sricharoen Migasena; Pravan Suntharasamai; Punnee Pitisuttithum; Dwip Kitayaporn; Chantapong Wasi; Wei Huang; Suphak Vanichseni; Charnchai Koompong; Jaranit Kaewkungwal; Suwanee Raktham; Tina Ippolito; Hanson; Timothy Gregory; William L. Heyward; Berman; Francis

May 1, 2000

Structure of chromosomal duplicons and their role in mediating human genomic disorders

Genome Research, ISSN: 10889051

Yonggang Ji; Evan E. Eichler; Stuart Schwartz; Robert D. Nicholls

April 28, 2000

Expression of the chemokine receptor CXCR2 in normal and neoplastic neuroendocrine cells

Archives of Pathology and Laboratory Medicine, ISSN: 00039985

Tülay Tecimer; Jeffrey Dlott; Anan Chuntharapai; Alvin W. Martin; Stephen C. Peiper

April 25, 2000

Application of cDNA microarrays in determining molecular phenotype in cardiac growth, development, and response to injury

Circulation, ISSN: 00097322

Sehl; Julie Tsu-Ning Tai; Kenneth J. Hillan; Lesley A. Brown; Goddard; Renhui Yang; Hongkui Jin; David G Lowe

April 15, 2000

Mapping of the C1q binding site on rituxan, a chimeric antibody with a human IgG1 Fc

Journal of Immunology, ISSN: 00221767

Esohe E. Idusogie; Presta; Hélène Gazzano-Santoro; Klara Totpal; Pin-Yee Wong; Ultsch; Meng; Michael G. Mulkerrin

April 14, 2000

Characterization of calcium release-activated apoptosis of LNCaP prostate cancer cells

Journal of Biological Chemistry, ISSN: 00219258

Ingrid E. Wertz; Vishva M. Dixit

April 7, 2000

Quantitative expression analysis of genes regulated by both obesity and leptin reveals a regulatory loop between leptin and pituitary-derived ACTH

Journal of Biological Chemistry, ISSN: 00219258

Renz; Elizabeth Tomlinson; Hultgren; Nancy Levin; Qimin Gu; Richard A. Shimkets; Lewin; Stewart

April 7, 2000

Identification of the mechanism responsible for the increased fibrin specificity of TNK-tissue plasminogen activator relative to tissue plasminogen activator

Journal of Biological Chemistry, ISSN: 00219258

Ronald J. Stewart; James C. Fredenburgh; Beverly A. Leslie; Keyt; Janice A. Rischke; Jeffrey I. Weitz

April 4, 2000

Deciphering the role of the electrostatic interactions involving Gly70 in eglin c by total chemical protein synthesis

Biochemistry, ISSN: 00062960

Wei-Yue Lu; Melissa A. Starovasnik; John J. Dwyer; Anthony A. Kossiakoff; Stephen B. H. Kent; Wuyuan Lu

April 1, 2000

Antagonists of protein-protein interactions

Chemistry and Biology, ISSN: 10745521

Andrea G Cochran

April 1, 2000

Conditional inactivation of VEGF-A in areas of collagen2a1 expression results in embryonic lethality in the heterozygous state

Development (Cambridge), ISSN: 09501991

Jody Haigh; Hans-Peter Gerber; Napoleone Ferrara; Wagner

April 1, 2000

Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets

Nature Medicine, ISSN: 10788956

Raphael A. Clynes; Terri L. Towers; Presta; Jeffrey V. Ravetch

March 30, 2000

Peptide exosite inhibitors of factor VIIa as anticoagulants

Nature, ISSN: 00280836

Dennis; Charles Elgenbrot; Nicholas J. Skelton; Ultsch; Santell; Dwyer; Mark P. O'Connell; Lazarus

March 30, 2000

Myoseverin, a microtubule-binding molecule with novel cellular effects

Nature Biotechnology, ISSN: 10870156

Gustavo R. Rosania; Young-Tae Chang; Omar Perez; Daniel P. Sutherlin; Helin Dong; David J. Lockhart; Peter G. Schultz

March 30, 2000

Modulating pharmacokinetics of an anti-interleukin-8 F(ab')2 by amine- specific PEGylation with preserved bioactivity

International Journal of Pharmaceutics, ISSN: 03785173

Iphigenia Koumenis; Shahrokh; Leong; Vanessa Hsei; Laura DeForge; Gerardo Zapata

March 30, 2000

Nasal epithelial permeation of thymotrinan (TP3) versus thymocartin (TP4): Competitive metabolism and self-enhancement

Pharmaceutical Research, ISSN: 07248741

M. Christiane Schmidt; Rubas; Hans P. Merkle

March 30, 2000

Quantitative determination of SC-68328 in dog plasma using flow injection and tandem mass spectrometry

Journal of Mass Spectrometry, ISSN: 10765174

Ji Y. Zhang; Douglas M. Fast; Grant L. Schoenhard; Vinod K. Arora; Frank J. Belas; Ian A. Blair

March 27, 2000

Lipopolysaccharide induces expression of APO2 ligand/TRAIL in human monocytes and macrophages

Scandinavian Journal of Immunology, ISSN: 03009475

Halaas; Vik; Ashkenazu; Espevik

March 18, 2000

Interactions of HIV protease inhibitors with a human organic cation transporter in a mammalian expression system

Drug Metabolism and Disposition, ISSN: 00909556

Lei Zhang; Wenche Gorset; Carla Washington; Terrence F. Blaschke; Deanna L. Kroetz; Kathleen M. Giacomini

March 17, 2000

Highly organized spherical hosts that bind organic guests in aqueous solution with micromolar affinity: Microcalorimetry studies

Chemistry - A European Journal, ISSN: 09476539

Evgueni L. Piatnitski; Robert A. Flowers II; Deshayes

March 17, 2000

TrkA amino acids controlling specificity for nerve growth factor

Journal of Biological Chemistry, ISSN: 00219258

O'Connell; Hongo; Presta; Tsoulfas

March 14, 2000

A phase II trial of nerve growth factor for sensory neuropathy associated with HIV infection

Neurology, ISSN: 00283878

McArthur; Yiannoutsos; Simpson; Bruce T. Adornato; Singer; Hollander; Marra; Rubin; Cohen; Tucker; Navia; Schifitto; Katzenstein; Rask; Zaborski; Smith; Shriver; Millar; Clifford

March 13, 2000

Spinal motor axons and neural crest cells use different molecular guides for segmental migration through the rostral half-somite

Journal of Neurobiology, ISSN: 00223034

Koblar; Krull; Pasquale; McLennan; Peale; Cerretti; Bothwell

March 13, 2000

Treatment and outcome of myocardial infarction in hospitals with and without invasive capability

Journal of the American College of Cardiology, ISSN: 07351097

William J. Rogers; John G. Canto; Hal V. Barron; Joseph A Boscarino; David A. Shoultz; Nathan R. Every

March 10, 2000

Macromolecular inhibitors of HIV-1 protease. Characterization of designed heterodimers

Journal of Biological Chemistry, ISSN: 00219258

James E. Rozzelle; Deborah S. Dauber; Stephen Todd; Robert F. Kelley; Charles S. Craik

March 7, 2000

Recombinant human thrombopoietin attenuates carboplatin-induced severe thrombocytopenia and the need for platelet transfusions in patients with gynecologic cancer

Annals of Internal Medicine, ISSN: 00034819

Saroj Vadhan-Raj; Claire F. Verschraegen; Carlos Bueso-Ramos; Hal E. Broxmeyer; Andrzej P. Kudelka; Ralph S. Freedman; Creighton L. Edwards; David Gershenson; Jones Jr.; Ashby; John J. Kavanagh

March 3, 2000

Wnt signaling in oncogenesis and embryogenesis - A look outside the nucleus

Science, ISSN: 00368075

Mark Peifer; Paul G. Polakis

March 2, 2000

Toll genes and responsiveness to bacterial endotoxins [7] (multiple letters)

New England Journal of Medicine, ISSN: 00284793

James A. Thomas; Robert L. Modlin; Hans D. Brightbill; Godowski

March 1, 2000

Receptor-binding conformation of the 'ELR' motif of IL-8: X-ray structure of the L5C/H33C variant at 2.35 Å resolution

Proteins: Structure, Function and Bioinformatics, ISSN: 08873585

Nancy Gerber; Henry B. Lowman; Dean R. Artis; Eigenbrot

March 1, 2000

Do nerve growth factor-related mechanisms contribute to loss of cutaneous nociception in leprosy?

Pain, ISSN: 03043959

Paul Facer; Dawn Mann; Rajeev Mathur; Shubha Pandya; Uma Ladiwala; Bhim Singhal; Hongo; Sinicropi; Giorgio Terenghi; Anand

March 1, 2000

WISP-1 is a Wnt-1- and β-catenin-responsive oncogene

Genes and Development, ISSN: 08909369

Lifeng Xu; Ryan B. Corcoran; James W. Welsh; Diane Pennica; Arnold J. Levine

March 1, 2000

International union of pharmacology. XXII. Nomenclature for chemokine receptors

Pharmacological Reviews, ISSN: 00316997

Philip M. Murphy; Marco Baggiolini; Israel F. Charo; Hébert; Richard Horuk; Kouji Matsushima; Miller; Joost J. Oppenheim; Christine A. Power

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