Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11951 - 12000 OF 15583 RESULTS

Putting the pieces together: contribution of fluorescence polarization assays to small molecule lead optimization
Proceedings of SPIE - The International Society for Optical Engineering, ISSN: 0277786X
Keating; James C. Marsters Jr.; Beresini; Ladner; Kimberly Zioncheck; Clark; Arellano; Bodary
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The 2.0 Å structure of bovine interferon-γ; assessment of the structural differences between species
Acta Crystallographica Section D: Biological Crystallography, ISSN: 09074449
Michael Randal; Anthony A. Kossiakoff
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The glial cell line-derived neurotrophic factor family receptor components are differentially regulated within sensory neurons after nerve injury
Journal of Neuroscience, ISSN: 02706474
David L. H. Bennett; Timothy J. Boucher; Armanini; Kris Poulsen; Gregory J. Michael; John V. Priestley; Phillips; McMahon; David L. Shelton
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The importance of growth hormone replacement therapy for bone mass in young adults with growth hormone deficiency
Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X
Kenneth M. Attie
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A reversed-phase HPLC assay for plasminogen activators
Journal of Liquid Chromatography and Related Technologies, ISSN: 10826076
Yuan Xu; Cacia
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APO2L/TRAIL expression in human brain tumors
Acta Neuropathologica, ISSN: 00016322
Mitsutoshi Nakamura; Johannes Rieger; Michael Weller; Jin Kim; Paul Kleihues; Hiroko Ohgaki
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Growth hormone safety update from the National Cooperative Growth Study
Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X
Thomas J. Maneatis; Joyce Baptista; Connelly; Sandra L. Blethen
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Role of the distal half of the c-Mpl intracellular domain in control of platelet production by thrombopoietin in vivo
Molecular and Cellular Biology, ISSN: 02707306
Shiuh-Ming Luoh; Stefanich; Gregg Solar; Hope Steinmetz; Michael T. Lipari; Tamara I. Pestina; Carl W. Jackson; Frederic J. De Sauvage
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Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancer
International Journal of Cancer, ISSN: 00207136
Jun Itakura; Toshiyuki Ishiwata; Shen; Marko Kornmann; Murray Korc
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Analysis of PTCH/SMO/SHH pathway genes in medulloblastoma
Genes Chromosomes and Cancer, ISSN: 10452257
Russell H. Zurawel; Cory Allen; Sharon Chiappa; Walter Cato; Jaclyn Biegel; Philip Cogen; Frederic J. De Sauvage; Corey Raffel
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Angiography of fluoresceinated anti-vascular endothelial growth factor antibody and dextrans in experimental choroidal neovascularization
Archives of Ophthalmology, ISSN: 00039950
Michael J. Tolentino; Deeba Husain; Panagiotis Theodosiadis; Evangelos S. Gragoudas; Edward Connolly; Jeanne Kahn; Cleland; Anthony P. Adamis; R. Andrew Cuthbertson; Joan W. Miller
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The seven-transmembrane receptor Smoothened cell-autonomously induces multiple ventral cell types
Nature Neuroscience, ISSN: 10976256
Mary Hynes; Weilan Ye; Kevin Wang; Donna Stone; Maximilien Murone; Frederic J. De Sauvage; Rosenthal
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The nucleoskeleton: Go EAST, young man
Nature Cell Biology, ISSN: 14657392
Lasky
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Clonidine for smoking cessation.
Cochrane database of systematic reviews (Online : Update Software), ISSN: 1469493X
Steven G. Gourlay; Stead; Neal L. Benowitz
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Gene expression profiling in an in vitro model of angiogenesis
American Journal of Pathology, ISSN: 00029440
Jeanne Kahn; Fuad Mehraban; Gladys S. Ingle; Xiaohua Xin; Juliet E. Bryant; Gordon A. Vehar; Schoenfeld; Grimaldi; Franklin V. Peale Jr.; Aparna Draksharapu; Lewin; Mary E. Gerritsen
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Toll-like receptor 2-mediated NF-κB activation requires a Rac I-dependent pathway
Nature Immunology, ISSN: 15292908
Laurence Arbibe; Jean-Paul Mira; Nicole Teusch; Lois Kline; Mausumee Guha; Nigel Mackman; Godowski; Richard J. Ulevitch; Ulla G. Knaus
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Pharmacokinetics and pharmacodynamics of tenecteplase: Results from a phase II study in patients with acute myocardial infarction
Journal of Clinical Pharmacology, ISSN: 00912700
Modi; Fox; Fong-Wong Clow; Tanswell; Christopher P. Cannon; Frans Van De Werf; Eugene Braunwald
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Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system
Neuron, ISSN: 08966273
Asa Abeliovich; Yvonne Schmitz; Isabel Fariñas; Choi-Lundberg; Ho; Pablo E. Castillo; Natasha Shinsky; Jose Manuel Garcia-Verdugo; Armanini; Anne Ryan; Mary Hynes; Phillips; David Sulzer; Rosenthal
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Comparison of the rates of deamidation, diketopiperazine formation, and oxidation in recombinant human vascular endothelial growth factor and model peptides
AAPS PharmSci, ISSN: 15221059
Chimanlall Goolcharran; Andrew J.S. Jones; Ronald T. Borchardt; Cleland; Rodney Keck
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Characterization of huJAM: Evidence for involvement in cell-cell contact and tight junction regulation
American Journal of Physiology - Cell Physiology, ISSN: 03636143
Tony W. Liang; Richard A. Demarco; Mrsny; Austin L. Gurney; Gray; Jeff Hooley; Holly L. Aaron; Arthur Huang; Toni Klassen; Daniel B. Tumas; Fong
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Purification of yeast mitochondrial Hsp60.
Methods in Molecular Biology, ISSN: 10643745
Yves Dubaquié; Renate Looser; Sabine Rospert
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Drug information in industry versus academia: A pharmacy resident's perspective of a sample case
Therapeutic Innovation and Regulatory Science, ISSN: 21684790
Graham; David A. Graves; Barry Grobman; Gary M. Mccart; Candy Tsourounis
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Expression of activated CDC42 induces T cell apoptosis in thymus and peripheral lymph organs via different pathways
Oncogene, ISSN: 09509232
Songqing Na; Baiyong Li; Iqbal S. Grewal; Hervé Enslen; Roger J. Davis; Jeffrey H. Hanke; Richard A. Flavell
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Treatment of allergic asthma with monoclonal anti-IgE antibody
New England Journal of Medicine, ISSN: 00284793
Henry Milgrom; Robert B. Fick Jr.; John Q. Su; Reimann; Robert K. Bush; Marc Watrous; W. James Metzger
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Baculovirus-based genetic screen for antiapoptotic genes identifies a novel IAP
Journal of Biological Chemistry, ISSN: 00219258
Somasekar Seshagiri; Domagoj Vucic; James Lee; Vishva M. Dixit
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Functional interaction between Gα(z) and Rap1GAP suggests a novel form of cellular cross-talk
Journal of Biological Chemistry, ISSN: 00219258
Jingwei Meng; Jennifer L. Glick; Paul G. Polakis; Patrick J. Casey
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Autosomal recessive chronic granulomatous disease caused by novel mutations in NCF-2, the gene encoding the p67-phox component of phagocyte NADPH oxidase
Human Genetics, ISSN: 03406717
Noack; Julie Rae; Andrew R. Cross; José Muñoz; Siham Salmen; José A. Mendoza; Nineth Rossi; John T. Curnutte; Heyworth
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Overexpression of thioredoxin h leads to enhanced activity of starch debranching enzyme (pullulanase) in barley grain
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Myeong-Je Cho; Joshua H. Wong; Corina Marx; Jiang; Peggy G. Lemaux; Bob B. Buchanan
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Development of bivalent (B/E) vaccines able to neutralize CCR5-dependent viruses from the United States and Thailand
Virology, ISSN: 00426822
Berman; Wei Huang; Riddle; Gray; Wrin; Vennari; Johnson; Michael Klaussen; Prashad; Christiane Köhne; Christina De Wit; Timothy Gregory
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Chapter 3.1.10 Targeting genes associated with mammalian behavior: past mistakes and future solutions
Techniques in the Behavioral and Neural Sciences, ISSN: 09210709
Gerlai
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Preface. Behavioral neurogenetics: the new synthesis
Techniques in the Behavioral and Neural Sciences, ISSN: 09210709
Wim E. Crusio; Gerlai
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Characterization of the human Suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli
Journal of Cell Science, ISSN: 00219533
Donna Stone; Maximilien Murone; Shiuh-Ming Luoh; Weilan Ye; Armanini; Austin L. Gurney; Phillips; Brush; Goddard; Frederic J. De Sauvage; Rosenthal
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Clinical applications of angiogenic growth factors and their inhibitors
Nature Medicine, ISSN: 10788956
Napoleone Ferrara; Kari Alitalo
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Chapter 3.2.7 Protein targeting in the functional analysis of EphA receptors: the use of immunoadhesins
Techniques in the Behavioral and Neural Sciences, ISSN: 09210709
Gerlai; Natasha Shinsky; Shih; P. Mickey Williams; Jane Winer; Armanini; Paul Moran; Cairns; Winslow; Gao; Phillips
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Activation of microglia reveals a non-proteolytic cytokine function for tissue plasminogen activator in the central nervous system
Journal of Cell Science, ISSN: 00219533
Andrew D. Rogove; Chia-Jen Siao; Keyt; Sidney Strickland; Stella E. Tsirka
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Recovery of severe sciatica
Spine, ISSN: 03622436
Federico Balagué; Margareta Nordin; Ali Sheikhzadeh; Anne-Catherine Echegoyen; Helena Brisby; Henri Marcel Hoogewoud; Pam Fredman; Mary Louise Skovron
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Chapter 2.2.4 Application of real-time RT-PCR for quantification of gene expression
Techniques in the Behavioral and Neural Sciences, ISSN: 09210709
Jane Winer; Natasha Shinsky; Gerlai; P. Mickey Williams
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Chapter 4.1 Ethological approaches in behavioral neurogenetic research
Techniques in the Behavioral and Neural Sciences, ISSN: 09210709
Gerlai
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Chapter 3.2.6 The use of immunoadhesins in neurobiology
Techniques in the Behavioral and Neural Sciences, ISSN: 09210709
David L. Shelton
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Control of apoptosis signaling by Apo2 ligand
Recent Progress in Hormone Research, ISSN: 00799963
Scot A. Marsters; Pitti; James P. Sheridan; Avi Ashkenazi
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Smaug, a novel and conserved protein, contributes to repression of nanos mRNA translation in vitro
RNA, ISSN: 13558382
Craig A. Smibert; Yung S. Lie; Wendy Shillinglaw; William J. Henzel; Paul M. Macdonald
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Prolonging cell-free protein synthesis with a novel ATP regeneration system
Biotechnology and Bioengineering, ISSN: 00063592
Dong-Myung Kim; James R. Swartz
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Chapter 2.1.8 Mutagenesis in zebra fish: studying the brain dopamine systems
Techniques in the Behavioral and Neural Sciences, ISSN: 09210709
Guo; Wolfgang Driever; Rosenthal
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Role of oestrogen therapy in the management of short stature in Turner syndrome
Acta Paediatrica, International Journal of Paediatrics, Supplement, ISSN: 08035326
Chernausek; Kenneth M. Attie
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Recombinant tissue-type plasminogen activator (Alteplase) for ischemic stroke 3 to 5 hours after symptom onset the ATLANTIS study: A randomized controlled trial
JAMA - Journal of the American Medical Association, ISSN: 00987484
Wayne M. Clark; Stanley Wissman; Gregory W. Albers; Jack H. Jhamandas; Kenneth Madden; Scott Hamilton
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Secretion of glycosylation site mutants can be rescued by the signal/pro sequence of tissue plasminogen activator
Journal of Cellular Biochemistry, ISSN: 07302312
Christiane Köhne; Johnson; Sabrina Tom; Peers; Richard L. Gehant; Hotaling; Dave Brousseau; Thomas Ryll; Judy Fox; Steven M. Chamow; Berman
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Validation of a rat pheochromocytoma (PC12)-based cell survival assay for determining biological potency of recombinant human nerve growth factor
Journal of Pharmaceutical and Biomedical Analysis, ISSN: 07317085
Hélène Gazzano-Santoro; Chen; Barbara Casto; Chu; Ellen Gilkerson; Mukku; Eleanor Canova-Davis; Claire Kotts
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Napsin A, a member of the aspartic protease family, is abundantly expressed in normal lung and kidney tissue and is expressed in lung adenocarcinomas
FEBS Letters, ISSN: 00145793
Yoshiko Chuman; Ann-Charlotte Bergman; Takayuki Ueno; Shin'Ichi Saito; Kazuyasu Sakaguchi; Ayodele A. Alaiya; Bo Franzén; Tomas Bergman; David Arnott; Gert Auer; Ettore Appella; Hans Jörnvall; Stig Linder
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Hedgehog signal transduction: From flies to vertebrates
Experimental Cell Research, ISSN: 00144827
Maximilien Murone; Rosenthal; Frederic J. De Sauvage
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Establishing equivalence by showing that a specified percentage of the effect of the active control over placebo is maintained
Journal of Biopharmaceutical Statistics, ISSN: 10543406
Holmgren
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