Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12401 - 12450 OF 15583 RESULTS

Experimental autoimmune encephalomyelitis induced with a combination of myelin basic protein and myelin oligodendrocyte glycoprotein is ameliorated by administration of a single myelin basic protein peptide
Journal of Immunology, ISSN: 00221767
Elizabeth A. Leadbetter; Cheryl R. Bourque; Devaux; Carl D. Olson; Geoffrey H. Sunshine; Shirish Hirani; Barbara P. Wallner; Dawn E. Smilek; Mary Pat Happ
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Contribution of domain interface residues to the stability of antibody C(H)3 domain homodimers
Biochemistry, ISSN: 00062960
William Dall'Acqua; Alexander L. Simon; Michael G. Mulkerrin; Paul J. Carter
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Effect of spray drying and subsequent processing conditions on residual moisture content and physical/biochemical stability of protein inhalation powders
Pharmaceutical Research, ISSN: 07248741
Maa; Phuong-Anh Nguyen; Andya; Nancy Dasovich; Sweeney; Steven J. Shire; Chung C. Hsu
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Backbone dynamics of the EGF-like domain of heregulin-α
Journal of Molecular Biology, ISSN: 00222836
Wayne J. Fairbrother; Jun Liu; Paul Pisacane; Mark X. Sliwkowski; Arthur G. Palmer III
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Molecular mimics of insulin-like growth factor 1 (IGF-1) for inhibiting IGF-I: IGF-binding protein interactions
Biochemistry, ISSN: 00062960
Henry B. Lowman; Chen; Nicholas J. Skelton; Deborah L. Mortensen; Elizabeth Tomlinson; Michael D Sadick; Icaf Robinson; Ross Clark
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DNAse treatment does not improve the survival of lupus prone (NZB x NZW)F1 mice
Lupus, ISSN: 09612033
Verthelyi; Noel Dybdal; Kathleen A. Elias; Klinman
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ERICE, a novel FLICE-activatable caspase
Journal of Biological Chemistry, ISSN: 00219258
Eric W. Humke; Jian Ni; Vishva M. Dixit
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Modulations in lipid A and phospholipid biosynthesis pathways influence outer membrane protein assembly in Escherichia coli K-12
Molecular Microbiology, ISSN: 0950382X
Andrew Kloser; Mike Laird; Ming Deng; Rajeev Misra
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The treatment of metastatic renal cell carcinoma patients with recombinant human gamma interferon
Cancer Journal from Scientific American, ISSN: 10814442
Small; Geoffrey R. Weiss; Umme K. Malik; Philip J. Walther; David H. Johnson; George Wilding; Timothy Kuzel; Alex Bajamonde; Virginia Paton
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Retrovirus-mediated in vivo gene transfer in the replicating liver using recombinant hepatocyte growth factor without liver injury or partial hepatectomy
Human Gene Therapy, ISSN: 10430342
Ken-Ichiro Kosai; Finegold; Bich-Thuy Thi-Huynh; Margaret Tewson; Ching-Nan; Neil Bowles; Savio L. C. Woo; Ralph H. Schwall; Gretchen J. Darlington
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Gain-of-function Chinese hamster ovary mutants LEC18 and LEC14 each express a novel N-acetylglucosaminyltransferase activity
Journal of Biological Chemistry, ISSN: 00219258
T. Shantha Raju; Pamela Stanley
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Total chemical synthesis of bovine pancreatic trypsin inhibitor by native chemical ligation
FEBS Letters, ISSN: 00145793
Wuyuan Lu; Melissa A. Starovasnik; Stephen B. H. Kent
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EGF-induced redistribution of erbB2 on breast tumor cells: Flow and image cytometric energy transfer measurements
Communications in Clinical Cytometry, ISSN: 01964763
Péter Nagy; László Bene; Margit Balázs; William C. Hyun; Steven J. Lockett; Nancy Y. Chiang; Frederick Waldman; Burt G. Feuerstein; Sándor Damjanovich; János Szöllosi
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Differential dependency of unmyelinated and aδ epidermal and upper dermal innervation on neurotrophins, Trk receptors, and p75(LNGFR)
Developmental Biology, ISSN: 00121606
Rice; Albers; Davis; Silos-Santiago; Wilkinson; LeMaster; Ernfors; Smeyne; Aldskogius; Phillips; Barbacid; DeChiara; Yancopoulos; Dunne; Fundin
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Opposite effects of recombinant human transforming growth factor-β1 on bone regeneration in vivo: Effects of exclusion of periosteal cells by microporous membrane
Bone, ISSN: 87563282
Göran Zellin; Beck; Ross Hardwick; Linde
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FGF and Shh signals control dopaminergic and serotonergic cell fate in the anterior neural plate
Cell, ISSN: 00928674
Weilan Ye; Kenji Shimamura; John L. R. Rubenstein; Mary Hynes; Rosenthal
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Pilot study of the immunologic effects of recombinant human growth hormone and recombinant insulin-like growth factor in HIV-infected patients
AIDS, ISSN: 02699370
Bach-Yen Nguyen; Mario Clerici; David J. Venzon; Sergio Bauza; William J. Murphy; Dan L. Longo; Michael Baseler; Gesundheit; Samuel Broder; Gene Shearer; Robert Yarchoan
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GDNF is abundant in the adult rat gut
Journal of the Autonomic Nervous System, ISSN: 01651838
Robert J. Peters; Mark A. Osinski; Hongo; Bennett; Angela J. Okragly; Haak-Frendscho; Miles L. Epstein
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Signal Transduction
Scientist, ISSN: 08903670
Vishva M. Dixit
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Vascular endothelial growth factor induces expression of the antiapoptotic proteins Bcl-2 and A1 in vascular endothelial cells
Journal of Biological Chemistry, ISSN: 00219258
Hans-Peter Gerber; Vishva M. Dixit; Napoleone Ferrara
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Water sorption behavior of lyophilized protein-sugar systems and implications for solid-state interactions
International Journal of Pharmaceutics, ISSN: 03785173
Henry R. Costantino; Curley; Sylvia Wu; Chung C. Hsu
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Solution structure of the heparin-binding domain of vascular endothelial growth factor
Structure, ISSN: 09692126
Wayne J. Fairbrother; Mark Champe; Hans W. Christinger; Keyt; Melissa A. Starovasnik
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A mutational analysis of binding interactions in an antigen-antibody protein-protein complex
Biochemistry, ISSN: 00062960
William Dall'Acqua; Ellen R. Goldman; Wenhong Lin; Connie Teng; Daisuke Tsuchiya; Hongmin Li; Xavier Ysern; Bradford C. Braden; Yili Li; Sandra J. Smith-Gill; Roy A. Mariuzza
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Hyperactivity of human DNase I variants: Dependence on the number of positively charged residues and concentration, length, and environment of DNA
Journal of Biological Chemistry, ISSN: 00219258
Clark Q. Pan; Lazarus
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Selection of heregulin variants having higher affinity for the ErbB3 receptor by monovalent phage display
Journal of Biological Chemistry, ISSN: 00219258
Ballinger; Jennifer T. Jones; Julie A. Lofgren; Wayne J. Fairbrother; Robert W. Akita; Mark X. Sliwkowski; James A. Wells
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Binding interaction of the heregulinβ egf domain with ErbB3 and ErbB4 receptors assessed by alanine scanning mutagenesis
Journal of Biological Chemistry, ISSN: 00219258
Jennifer T. Jones; Ballinger; Paul Pisacane; Julie A. Lofgren; V. Danial Fitzpatrick; Wayne J. Fairbrother; James A. Wells; Mark X. Sliwkowski
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Peroxisome degradation by microautophagy in Pichia pastoris: Identification of specific steps and morphological intermediates
Journal of Cell Biology, ISSN: 00219525
Yasuyoshi Sakai; Antonius Koller; Linda Rangell; Gilbert-Andre Keller; Suresh Subramani
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A multicenter study of platelet recovery and utilization in patients after myeloablative therapy and hematopoietic stem cell transplantation
Blood, ISSN: 00064971
Bernstein; Auayporn P. Nademanee; Julie Vose; Guido Tricot; Fay; Robert Negrin; John DiPersio; Gabriela Rondon; Richard Champlin; Michael J. Barnett; Kenneth Cornetta; Geoffrey P. Herzig; William Vaughan; George Geils Jr.; Armand Keating; Hans Messner; Wolff; Kenneth B. Miller; Charles Linker; Mitchell S. Cairo; Hellmann; Ashby; Scott Stryker; Richard A. Nash
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Antigenic profiles of endothelial and hemopoietic lineages in murine intraembryonic hemogenic sites
Developmental and Comparative Immunology, ISSN: 0145305X
Juan A. Garcia-Porrero; Alexandra Manaia; Jaime Jimeno; Lasky; Françoise Dieterlen-Lièvre; Isabelle E. Godin
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Disruption of the Jak1 gene demonstrates obligatory and nonredundant roles of the Jaks in cytokine-induced biologic responses
Cell, ISSN: 00928674
Scott J. Rodig; Marco A. Meraz; J. Michael White; Patricia A. Lampe; Riley; Cora D. Arthur; King; Kathleen C. Sheehan; Li Yin; Diane Pennica; Eugene M. Johnson Jr.; Schreiber
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Body composition of HIV/AIDS males: Effects of treatment with insulin- like growth factor (IGF-I) and growth hormone (GH)
Applied Radiation and Isotopes, ISSN: 09698043
Ellis; Lee; Pivarnik; Julie Bukar; Gesundheit
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APO2 ligand: A novel lethal weapon against malignant glioma?
FEBS Letters, ISSN: 00145793
Johannes Rieger; Ulrike Naumann; Tamara Glaser; Avi Ashkenazi; Michael Weller
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Environmental control and monitoring in bulk manufacturing facilities for biological products
Pharmaceutical Technology, ISSN: 01478087
Joe Barta
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The peptidyl-prolyl isomerase domain of the CyP-40 cyclophilin homolog Cpr7 is not required to support growth or glucocorticoid receptor activity in Saccharomyces cerevisiae
Journal of Biological Chemistry, ISSN: 00219258
Andrea A. Duina; James A. Marsh; Richard B. Kurtz; Hui-Chen Jane Chang; Susan Lindquist; Richard F. Gaber
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Adaptive calibration scheme for quantification of nutrients and byproducts in insect cell bioreactors by near-infrared spectroscopy
Biotechnology Progress, ISSN: 87567938
Mark R. Rileys; Mark A. Arnold; David W. Murhammer; Ed L. Walls; Neslihan DelaCruz
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Requirements for binding and signaling of the kinase domain receptor for vascular endothelial growth factor
Journal of Biological Chemistry, ISSN: 00219258
Fuh; Bing Li; Crowley; Cunningham; James A. Wells
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A high-throughput microscale method to release N-linked oligosaccharides from glycoproteins for matrix-assisted laser desorption/ionizatiom time-of-flight mass spectrometric analysis
Glycobiology, ISSN: 09596658
Damon I. Papac; Briggs; Chin; Andrew J.S. Jones
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Interferon gamma-1b compared with placebo in metastatic renal-cell carcinoma
New England Journal of Medicine, ISSN: 00284793
Martin E. Gleave; Mostafa Elhilali; Yves Fradet; Ian Davis; Peter Venner; Fred Saad; Laurence H. Klotz; Moore; Virginia Paton; Alex Bajamonde; David Bell; Scott Ernst; Ernest Ramsey; Joe Chin; Alvaro Morales; Heidi Martins; Corsee Sanders
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Stability of alkoxycarbonylamidine prodrugs
Pharmaceutical Research, ISSN: 07248741
Shahrokh; Eric Lee; Alan G. Olivero; Regina A. Matamores; Kirk D. Robarge; Arthur Lee; Kenneth J. Weise; Brent Blackburn; Powell
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Recognition properties of a sequence-specific DNA binding antibody
Biochemistry, ISSN: 00062960
James F. LeBlanc; Kathryn E. McLane; Paul W. H. I. Parren; Dennis R. Burton; Peter Ghazal
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Identification of a ligand for the death-domain-containing receptor Apo3
Current Biology, ISSN: 09609822
Scot A. Marsters; James P. Sheridan; Pitti; Brush; Goddard; Avi Ashkenazi
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Calpain inhibitors, but not caspase inhibitors, prevent actin proteolysis and DNA fragmentation during apoptosis
Journal of Cell Science, ISSN: 00219533
Pascal G. Villa; William J. Henzel; Monique Sensenbrenner; Christopher E. Henderson; Brigitte Pettmann
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Cranial computed tomography interpretation in acute stroke: Physician accuracy in determining eligibility for thrombolytic therapy
JAMA - Journal of the American Medical Association, ISSN: 00987484
David L. Schriger; Mary Kalafut; Sidney Starkman; Michelle Krueger; Jeffrey L. Saver
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Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity
Journal of Molecular Biology, ISSN: 00222836
Clackson; Ultsch; James A. Wells; De Vos
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Characterization of V3 loop-Pseudomonas exotoxin chimeras: Candidate vaccines for human immunodeficiency virus-1
Journal of Biological Chemistry, ISSN: 00219258
David FitzGerald; Charlotte M. Fryling; Marian McKee; Vennari; Wrin; Cromwell; Daugherty; Mrsny
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A p55 TNF receptor immunoadhesin prevents T cell-mediated intestinal injury by inhibiting matrix metalloproteinase production
Journal of Immunology, ISSN: 00221767
Sylvia L. F. Pender; John M. E. Fell; Steven M. Chamow; Avi Ashkenazi; Thomas T. MacDonald
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Vascular endothelial growth factor is essential for corpus luteum angiogenesis
Nature Medicine, ISSN: 10788956
Napoleone Ferrara; Helen Chen; Terri Davis-Smyth; Hans-Peter Gerber; Thuy-Nhung Nguyen; Peers; Chisholm; Kenneth J. Hillan; Ralph H. Schwall
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A large-scale process to produce microencapsulated proteins
Pharmaceutical Research, ISSN: 07248741
Paul Herbert; Keith Murphy; OluFunmi Johnson; Nan Dong; Warren Jaworowicz; Mark A. Tracy; Cleland; Putney
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An integrated approach to proteome analysis: Identification of proteins associated with cardiac hypertrophy
Analytical Biochemistry, ISSN: 00032697
David Arnott; Kathy L. O'Connell; King; Stults
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Activation of caspases triggered by cytochrome c in vitro
FEBS Letters, ISSN: 00145793
Guoha Pan; Eric W. Humke; Vishva M. Dixit
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