Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12801 - 12850 OF 15578 RESULTS

January 1, 1997

Partial growth-hormone insensitivity: The role of growth-hormone receptor mutations in idiopathic stature

Journal of Pediatrics, ISSN: 00223476

Goddard; Patrick Dowd; Chernausek; Geffner; Gertner; Hintz; Hopwood; Selna L. Kaplan; Plotnick; Alan D. Rogol; Rosenfield; Saenger; Nelly Mauras; Hershkopf; Angulo; Kenneth M. Attie

January 1, 1997

Pioneering recombinant growth hormone manufacturing: Pounds produced per mile of height

Journal of Pediatrics, ISSN: 00223476

Cronin

January 1, 1997

National Cooperative Growth Study substudy VI: The clinical utility of growth-hormone-binding protein, insulin-like growth factor I, and insulin- like growth factor-binding protein 3 measurements

Journal of Pediatrics, ISSN: 00223476

Kenneth M. Attie; Joanne R. Julius; Catherine Stoppani; Amy Chen Rundle

January 1, 1997

A risk-benefit assessment of growth hormone use in children

Drug Safety, ISSN: 01145916

Sandra L. Blethen; Margaret H. Macgillivray

January 1, 1997

Peripheral vascular stenosis in apolipoprotein e-deficient mice: Potential roles of lipid deposition, medial atrophy, and adventitial inflammation

Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642

Hong Seog Seo; Donna M. Lombardi; Patti Polinsky; Powell-Braxton; Bunting; Schwartz; Michael E. Rosenfeld

January 1, 1997

Determining the water sorption monolayer of lyophilized pharmaceutical proteins

Journal of Pharmaceutical Sciences, ISSN: 00223549

Henry R. Costantino; Curley; Chung C. Hsu

January 1, 1997

Developing Pharmaceutical Protein Formulations: Assumptions and Analytical Tools

ACS Symposium Series, ISSN: 00976156

Shahrokh

January 1, 1997

Targeting technologies - The expanding patent literature

Journal of Drug Targeting, ISSN: 1061186X

Mrsny

January 1, 1997

Specification and Survival of Dopaminergic Neurons in the Mammalian Midbrain

Advances in Pharmacology, ISSN: 10543589

Rosenthal

January 1, 1997

NGF binding to p75 enhances the sensitivity of sensory and sympathetic neurons to NGF at different stages of development

Molecular and Cellular Neuroscience, ISSN: 10447431

Antony Horton; Laramee; Sean Wyatt; Shih; Winslow; Alun M. Davies

January 1, 1997

Hematologically important mutations: X-linked chronic granulomatous disease - An update

Blood Cells, Molecules, and Diseases, ISSN: 10799796

Heyworth; John T. Curnutte; Julie Rae; Noack; Andrew R. Cross

January 1, 1997

P-115. Recombinant human (rh) GHBP: Effects on GH action in the rat

Endocrinology and Metabolism, Supplement, ISSN: 1074939X

Deborah L. Mortensen; Carlsson; Winkler; Ross Clark

January 1, 1997

The Pharmaceutical Development of Insulin: Historical Perspectives and Future Directions

ACS Symposium Series, ISSN: 00976156

Henry R. Costantino; Stanley Liauw; Samir Mitragotri; Langer; Klibanov; Victoria Sluzky

January 1, 1997

Growth hormone/IGF-I and/or resistive exercise maintains myonuclear number in hindlimb unweighted muscles

Journal of Applied Physiology, ISSN: 87507587

Allen; Jon K. Linderman; Roy; Richard E. Grindeland; Mukku; Edgerton

January 1, 1997

MyD88: An adapter that recruits IRAK to the IL-1 receptor complex

Immunity, ISSN: 10747613

Holger Wesche; William J. Henzel; Wendy Shillinglaw; Shyun Li; Zhaodan Cao

January 1, 1997

The role of assay validation in specification development.

Developments in biological standardization, ISSN: 03015149

Baffi

January 1, 1997

O-015. rhIGF-I: Differential sensitivity to SQ bolus vs continuous delivery

Endocrinology and Metabolism, Supplement, ISSN: 1074939X

Nelly Mauras; Paul M. Martha Jr.; Quarmby; Haymond

January 1, 1997

Preparation and Characterization of Poly(ethylene glycol)ylated Human Growth Hormone Antagonist

ACS Symposium Series, ISSN: 00976156

Olson; Richard L. Gehant; Mukku; Kathy L. O'Connell; Brandon Tomlinson; Klara Totpal; Winkler

January 1, 1997

Specifications from a biotechnology industry perspective.

Developments in biological standardization, ISSN: 03015149

Robert L. Garnick

January 1, 1997

Csk and BatK Show Opposite Temporal Expression in the Rat CMS: Consistent with its Late Expression in Development, BatK Induces Differentiation of PC12 Cells

European Journal of Neuroscience, ISSN: 0953816X

Sophia S. Kuo

January 1, 1997

Process model and recipe structure, the conceptual design for a flexible batch plant

ISA Transactions, ISSN: 00190578

Hans Koning-Bastiaan

January 1, 1997

Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation

American Journal of Physiology - Cell Physiology, ISSN: 03636143

Turner; Brian K. Rill; Susan L. Carlson; Denice K. Carnes; Rachel Kerner; Mrsny; James L. Madara

January 1, 1997

Normal platelets and megakaryocytes are produced in vivo in the absence of thrombopoietin

Blood, ISSN: 00064971

Bunting; Ramon Widmer; Michael T. Lipari; Linda Rangell; Hope Steinmetz; Karen Carver-Moore; Mark Moore; Gilbert-Andre Keller; Frederic J. De Sauvage

January 1, 1997

Stimulating effect of both human recombinant inhibin A and activin A on immature porcine Leydig cell functions in vitro

Endocrinology, ISSN: 00137227

Hervé Lejeune; Franck Chuzel; Pascale Sanchez; Philippe Durand; Mather; José M. Saez

January 1, 1997

Analysis of rat vestibular hair cell development and regeneration using calretinin as an early marker

Journal of Neuroscience, ISSN: 02706474

Zheng; Gao

January 1, 1997

Mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Its binding motif for α4β7 and role in experimental colitis

Immunologic Research, ISSN: 0257277X

Sherman Fong; Susan Jones; Renz; Chiu; Anne Ryan; Presta; Jackson

January 1, 1997

Antioxidants for prevention of methionine oxidation in recombinant monoclonal antibody HER2

Journal of Pharmaceutical Sciences, ISSN: 00223549

Lam; Yang; Cleland

January 1, 1997

Promiscuous use of CC and CXC chemokine receptors in cell-to-cell fusion mediated by a human immunodeficiency virus type 2 envelope protein

Journal of Virology, ISSN: 0022538X

Romke Bron; Klasse; David Wilkinson; Clapham; Annegret Pelchen-Matthews; Christine A. Power; Timothy N. C. Wells; Jin Kim; Stephen C. Peiper; James A. Hoxie; Mark Marsh

January 1, 1997

Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase

Stroke, ISSN: 00392499

Walder; Green; Darbonne; Joanne Mathias; Julie Rae; Mary C. Dinauer; John T. Curnutte; G. Roger Thomas

January 1, 1997

Receptors for the chemoattractants C5a and IL-8 are clustered on the surface of human neutrophils

Journal of Histochemistry and Cytochemistry, ISSN: 00221554

Gary D. Gray; Sharon R. Hasslen; Julia A. Ember; David F. Carney; Michael J. Herron; Stanley L. Erlandsen; Robert D. Nelson

January 1, 1997

γ-heregulin: A novel heregulin isoform that is an autocrine growth factor for the human breast cancer cell line, MDA-MB-175

Oncogene, ISSN: 09509232

Gabriele Schaefer; V. Danial Fitzpatrick; Mark X. Sliwkowski

January 1, 1997

The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93 Å resolution: Multiple copy flexibility and receptor binding

Structure, ISSN: 09692126

Yves A. Muller; Hans W. Christinger; Keyt; De Vos

January 1, 1997

Murine endothelial cells support fetal liver erythropoiesis and myelopoiesis via distinct interactions

British Journal of Haematology, ISSN: 00071048

Osamu Ohneda; Victoria L. Bautch

January 1, 1997

Disruption of a single allele of the nerve growth factor gene results in atrophy of basal forebrain cholinergic neurons and memory deficits

Journal of Neuroscience, ISSN: 02706474

Grace Chan; Merry Nishimura; Armanini; Crowley; Spencer; Phillips

January 1, 1997

Lindane, an inhibitor of gap junction formation, abolishes oocyte directed follicle organizing activity in vitro

Endocrinology, ISSN: 00137227

Li; Mather

January 1, 1997

Growth hormone secretagogues stimulate the hypothalamic-pituitary- adrenal axis and are diabetogenic in the Zucker diabetic fatty rat

Endocrinology, ISSN: 00137227

Ross Clark; Thomas; Deborah L. Mortensen; Wesley B. Won; Yan Hui Ma; Elizabeth Tomlinson; Fairhall; Icaf Robinson

January 1, 1997

Growth hormone and insulin-like growth factor 1: New endocrine therapies in cardiology?

Trends in Cardiovascular Medicine, ISSN: 10501738

Ross Clark

January 1, 1997

IFN-γ inducibility of class II transactivator is specifically lacking in human tumour lines: Relevance to retinoblastoma protein rescue of IFN-γ inducibility of the HLA class II genes

Immunology and Cell Biology, ISSN: 08189641

Yanmei Lu; Michael E. Tschickardt; Brian J. Schmidt; George Blanck

January 1, 1997

Apoptosis: A mechanism contributing to remodeling of skeletal muscle in response to hindlimb unweighting

American Journal of Physiology - Cell Physiology, ISSN: 03636143

Allen; Jon K. Linderman; Roy; Allison J. Bigbee; Richard E. Grindeland; Mukku; Edgerton

January 1, 1997

1H, 13C, and 15N backbone assignment and secondary structure of the receptor-binding domain of vascular endothelial growth factor

Protein Science, ISSN: 09618368

Wayne J. Fairbrother; Mark Champe; Hans W. Christinger; Keyt; Melissa A. Starovasnik

January 1, 1997

A new method for bronchial-provocation testing in asthmatic subjects using a dry powder of mannitol

American Journal of Respiratory and Critical Care Medicine, ISSN: 1073449X

Anderson; John Brannan; Spring; Spalding; Rodwell; Chan; Gonda; Andrew J. Walsh; Clark

January 1, 1997

Rb interacts with TAF(II)250/TFIID through multiple domains

Oncogene, ISSN: 09509232

Zhaohui Shao; Jennifer L. Siegert; Siegfried Ruppert; Paul D. Robbins

January 1, 1997

A human colonic cell line sharing similarities with enterocytes as a model to examine oral absorption: Advantages and limitations of the Caco-2 model

Critical Reviews in Therapeutic Drug Carrier Systems, ISSN: 07434863

Delie; Rubas

January 1, 1997

Human pregnancy serum contains at least two distinct proteolytic activities with the ability to degrade insulin-like growth factor binding protein-3

Endocrinology, ISSN: 00137227

Peter Bang; Fielder

January 1, 1997

Lerk2 (ephrin-b1) is a collapsing factor for a subset of cortical growth cones and acts by a mechanism different from AL-1 (ephrin-a5)

Molecular and Cellular Neuroscience, ISSN: 10447431

Leonie Meima; Paul Moran; William Matthews; Caras

January 1, 1997

Crystal structures of bovine chymotrypsin and trypsin complexed to the inhibitor domain of Alzheimer's amyloid β-protein precursor (APPI) and basic pancreatic trypsin inhibitor (BPTI): Engineering of inhibitors with altered specificities

Protein Science, ISSN: 09618368

Axel J. Scheidig; Thomas R. Hynes; Laura A. Pelletier; James A. Wells; Anthony A. Kossiakoff

January 1, 1997

Regulation of interleukin 6 expression by cardiotrophin 1

Cytokine, ISSN: 10434666

Olivier Robledo; Sylvie Chevalier; Josy Froger; Annick Barthelaix-Pouplard; Diane Pennica; Hugues Gascan

January 1, 1997

Neurotrophins and time: Different roles for TrkB signaling in hippocampal long-term potentiation

Neuron, ISSN: 08966273

Hyejin Kang; Andy A. Welcher; David L. Shelton; Erin M. Schuman

January 1, 1997

Dissociation of antithrombotic effect and bleeding time prolongation in rabbits by inhibiting tissue factor function

Thrombosis and Haemostasis, ISSN: 03406245

Jacques Himber; Daniel Kirchhofer; Markus A. Riederer; Thomas B. Tschopp; Beat Steiner; Roux

January 1, 1997

Insulin-degrading enzyme does not require peroxisomal localization for insulin degradation

Endocrinology, ISSN: 00137227

Valérie Chesneau; Rachel K. Perlman; Wenlu Li; Gilbert-Andre Keller; Marsha Rich Rosner

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