Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12951 - 13000 OF 15578 RESULTS

Human hepatocyte growth factor in alcoholic liver disease: A comparison with change in α-fetoprotein
Alcoholism: Clinical and Experimental Research, ISSN: 01456008
Charles L. Mendenhall; Roos; Thomas E. Moritz; Gary A. Roselle; Antonio Chedid; Charles J. Grossman; Susan D. Rouster; Bennett; John R. Lake
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Analysis of mixture sequences derived from edman degradation data
Techniques in Protein Chemistry, ISSN: 10808914
William J. Henzel; Stults; Susan C. Wong; Angela K. Namenuk; James Yashio; Colin K. Watanabe
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Functional effects of lymphotoxin on crushed peripheral nerve
Microsurgery, ISSN: 07381085
Javier Algora; Long-En Chen; Anthony V. Seaber; Grace H.W. Wong; James R. Urbaniak
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Modulation of LFA-1 by an anti-cdlla antibody which distributes to lfa-1-expresslng cells in blood, spleen, liver, bone marrow, and kidney
FASEB Journal, ISSN: 08926638
Barbara Reitz; Washington; Hotaling; Wolfgang-feimball; Ryan; Ramon Widmer; Betty Chan; Gilbert-Andre Keller; Kenneth D. Bauer; Paula Jardieu; Judy Fox
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Humanization of an Anti-Lymphocyte Function-Associated Antigen (LFA)-1 Monoclonal Antibody and Reengineering of the Humanized Antibody for Binding to Rhesus LFA-1
Journal of Immunology, ISSN: 00221767
Winifred Werther; Gonzalez; Shane J. O'Connor; McCabe; Betty Chan; Hotaling; Mark Champe; Judy Fox; Paula Jardieu; Berman; Presta
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Cross-desensitisation of neutrophil IL-8 receptors involves differential receptor subtype regulation
Thorax, ISSN: 00406376
Ian Sabroe; Hébert; Timothy J. Williams; Paul D. Collins
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Factors affecting neuronal birth and death in the mammalian olfactory epithelium
CIBA Foundation Symposia, ISSN: 03005208
Anne L. Calof; J. David Holcomb; Jeffrey S. Mumm; Nobuko Hagiwara; Phu Tran; Kirk M. Smith; David L. Shelton
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Development of neurotrophic factor therapy for Alzheimer's disease
CIBA Foundation Symposia, ISSN: 03005208
Franz Hefti; Armanini; Klaus D. Beck; Caras; Grace Chan; Godowski; Goodman; R. Glenn Hammonds; Melanie R Mark; Paul Moran; Merry Nishimura; Phillips; Shih; Janet Valverde; Winslow
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Predominate neuronal localization of a soluble sialidase in Chinese hamster brain
FASEB Journal, ISSN: 08926638
Dybdal; Oline; Li; Li; Warner
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Elevated blood pressure and enhanced myocardial contractility in mice with severe IGF-1 deficiency
Journal of Clinical Investigation, ISSN: 00219738
Giuseppe Lembo; Howard A. Rockman; John J. Hunter; Hope Steinmetz; Walter J. Koch; Lan Ma; Morton P. Prinz; John Ross Jr.; Kenneth R. Chien; Powell-Braxton
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Identification of a GDP-L-fucose:polypeptide fucosyltransferase and enzymatic addition of O-linked fucose to EGF domains
Glycobiology, ISSN: 09596658
Yang Wang; Geoffrey F. Lee; Robert F. Kelley; Spellman
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Are there more members of the CNTF-GPA family?
Perspectives on Developmental Neurobiology, ISSN: 10640517
David L. Shelton
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Induction of autoimmune t cells and costimulatory ligands b7 and icam-1 by interferon-alpha
FASEB Journal, ISSN: 08926638
Debasis Chakrabarti; Hultgren; Timothy
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Induction of apoptosis by APO-2 ligand, a new member of the TNF cytokine family
FASEB Journal, ISSN: 08926638
Avi Ashkenazi; Pitti; Scot A. Marsters; Siegfried Ruppert; Christopher J. Donahue; Alison Moore
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Basement membrane and repair of injury to peripheral nerve: Defining a potential role for macrophages, matrix metalloproteinases, and tissue inhibitor of metalloproteinases-1
Journal of Experimental Medicine, ISSN: 00221007
Monique La Fleur; Johnnie L. Underwood; Daniel A. Rappolee; Zena Werb
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Molecular recognition in protein complexes
FASEB Journal, ISSN: 08926638
James A. Wells; Brian C. Cunnmgham; Betty Li; Melissa A. Starovasnik; Wayne J. Fairbrother; Andrew Braisted
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Structure-function studies of human interferon-a receptor II using mabs
FASEB Journal, ISSN: 08926638
Anan Chumharapai; Lu; Jin
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Modulation of LFA-1 by an anti-cdlla antibody which distributes to lfa-1-expresslng cells in blood, spleen, liver, bone marrow, and kidney
FASEB Journal, ISSN: 08926638
Barbara Reitz; Washington; Hotaling; Wolfgang-feimball; Anne Ryan; Ramon Widmer; Betty Chan; Gilbert-Andre Keller; Kenneth D. Bauer; Paula Jardieu; Judy Fox
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Induction of vascular endothelial growth factor by insulin-like growth factor 1 in colorectal carcinoma
Journal of Biological Chemistry, ISSN: 00219258
Robert S. Warren; Hui Yuan; Mary R. Matli; Napoleone Ferrara; David B. Donner
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Mouse RAD50 has limited epitopic homology to p53 and is expressed in the adult myocardium
Journal of Biological Chemistry, ISSN: 00219258
Kyung Keun Kim; Adil Daud; Susan C. Wong; Laura Pajak; Shih-Chong Tsai; He Wang; William J. Henzel; Loren J. Field
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Glycerophosphorylethanolamine (GPEA) identified as an hepatocyte growth stimulator in liver extracts
Experimental Cell Research, ISSN: 00144827
Nelson; Moffat; Neil E. Jacobsen; William J. Henzel; Stults; King; Amy E. McMurtrey; Richard L. Vandlen; Steven A. Spencer
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Recombinant human inhibin-A administered early in the menstrual cycle alters concurrent pituitary and follicular, plus subsequent luteal, function in rhesus monkeys
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Theodore A. Molskness; Woodruff; David L. Hess; Dahl; Richard L. Stouffer
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A longitudinal assessment of hormonal and physical alterations during normal puberty in boys. III. The neuroendocrine growth hormone axis during late prepuberty
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Paul M. Martha Jr.; Alan D. Rogol; Johannes D. Veldhuis; Robert M. Blizzard
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Spray-coating of rhDNase on lactose: Effect of system design, operational parameters and protein formulation
International Journal of Pharmaceutics, ISSN: 03785173
Maa; Phuong-Anh Nguyen; Chung C. Hsu
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Tumor necrosis factor receptors (Tnfr) in mouse fibroblasts deficient in Tnfr1 or Tnfr2 are signaling competent and activate the mitogen-activated protein kinase pathway with differential kinetics
Journal of Biological Chemistry, ISSN: 00219258
Alexandra Kalb; Horst Bluethmann; Mark Moore; Werner Lesslauer
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A negative regulatory region in the intracellular domain of the human interferon-α receptor
Journal of Biological Chemistry, ISSN: 00219258
Gibbs; Michelle Takahashi; Michel Aguet; Anan Chuntharapai
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Short-term GDNF treatment provides long-term rescue of lesioned nigral dopaminergic neurons in a rat model of Parkinson's disease
Journal of Neuroscience, ISSN: 02706474
Christian Winkler; Hans Sauer; Lee; Anders Bjorklund
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Confirmation by mass spectrometry of a trisulfide variant in methionyl human growth hormone biosynthesized in Escherichia coli
Analytical Chemistry, ISSN: 00032700
Eleanor Canova-Davis; Ida P. Baldonado; Chloupek; Victor Ling; Richard L. Gehant; Olson; Beth Gillece-Castro
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The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog
Nature, ISSN: 00280836
Donna Stone; Mary Hynes; Armanini; Todd A. Swanson; Qimin Gu; Ronald L. Johnson; Matthew P. Scott; Diane Pennica; Goddard; Phillips; Markus Noll; Joan E. Hooper; Frederic J. De Sauvage; Rosenthal
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An evaluation of the accuracy of four ELISA methods for measuring natural and recombinant human interferon-g
Journal of Immunological Methods, ISSN: 00221759
Paasch; Baron R. Reed; Rodney Keck; Bryan Sandlund; Ellen Gilkerson; Shalaby
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Developmental abnormalities and age-related neurodegeneration in a mouse model of Down syndrome
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
David M. Holtzman; Daniela Santucci; Joshua Kilbridge; Jane Chua-Couzens; David J. Fontana; Scott E. Daniels; Johnson; Grace Chan; Yuling Sun; Elaine J. Carlson; Enrico Alleva; Charles J. Epstein; William C. Mobley
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Purification of insulin-like growth factor-I and related proteins using underivatized silica
Journal of Chromatography A, ISSN: 00219673
David H. Reifsnyder; Charles V. Olson; Etcheverry; Prashad; Stuart E. Builder
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Furilisin: A variant of subtilisin BPN' engineered for cleaving tribasic substrates
Biochemistry, ISSN: 00062960
Ballinger; Jeffrey Tom; James A. Wells
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Design of biological equivalence programs for therapeutic biotechnology products in clinical development: A perspective
Pharmaceutical Research, ISSN: 07248741
Joyce Mordenti; Joy A. Cavagnaro; Green
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Stable formulations of recombinant human growth hormone and interferon-γ for microencapsulation in biodegradable microspheres
Pharmaceutical Research, ISSN: 07248741
Cleland; Andrew J.S. Jones
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L-Selectin Binds to P-Selectin Glycoprotein Ligand-1 on Leukocytes: Interactions between the Lectin, Epidermal Growth Factor, and Consensus Repeat Domains of the Selectins Determine Ligand Binding Specificity
Journal of Immunology, ISSN: 00221767
Lili Tu; Anjun Chen; Martha D. Delahunty; Kevin L. Moore; Susan R. Watson; Rodger P. McEver; Thomas F. Tedder
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Tissue distribution and complex formation with IgE of an anti-IgE antibody after intravenous administration in cynomolgus monkeys
Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565
Judy Fox; Hotaling; Craig Struble; Jane Ruppel; Dorothy J. Bates; Schoenhoff
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When perfectly HLA-matched kidneys are refused for transplant: Implications for a national cooperative sharing system
Journal of the American College of Surgeons, ISSN: 10727515
Mary D. Ellison; Timothy J. Breen; Darcy B. Davies; Erick B. Edwards; Richard J. Mahoney; Otis P. Daily; Douglas J. Norman
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Molten globule intermediate of recombinant human growth hormone: Stabilization with surfactants
Biotechnology Progress, ISSN: 87567938
Narendra B. Bam; Cleland; Theodore W. Randolph
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Involvement of interleukin (IL) 8 receptor in negative regulation of myeloid progenitor cells in vivo: Evidence from mice lacking the murine IL-8 receptor homologue
Journal of Experimental Medicine, ISSN: 00221007
Hal E. Broxmeyer; Scott Cooper; Cacalano; Hague; Edward Bailish; Mark Moore
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Interleukin-8 (IL-8), melanoma growth-stimulatory activity, and neutrophil-activating peptide selectively mediate priming of the neutrophil NADPH oxidase through the type A or type B IL-8 receptor
Journal of Biological Chemistry, ISSN: 00219258
Green; Anan Chuntharapai; John T. Curnutte
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On-line simultaneous monitoring of ammonia and glutamine in a hollow-fiber reactor using flow injection analysis
Journal of Biotechnology, ISSN: 01681656
Stoll; Ruffieux; Schneider; Von Stockar; Ian W. Marison
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Defective B Cell Development in Snell Dwarf (dw/dw) Mice Can Be Corrected by Thyroxine Treatment
Journal of Immunology, ISSN: 00221767
Encarnacion Montecino-Rodriguez; Ross Clark; Anne Johnson; Linda Collins; Kenneth Dorshkind
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Regulation of WT1 by phosphorylation: Inhibition of DNA binding, alteration of transcriptional activity and cellular translocation
EMBO Journal, ISSN: 02614189
Ying Ye; Baisakhi Raychaudhuri; Austin L. Gurney; Christine E. Campbell; Bryan R. G. Williams
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The renaturable 69- and 63-kDa protein kinases that undergo rapid activation in chemoattractant-stimulated guinea pig neutrophils are p21- activated kinases
Journal of Biological Chemistry, ISSN: 00219258
Jiabing Ding; Ulla G. Knaus; Jian P. Lian; Bokoch; John A. Badwey
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Therapeutic angiogenesis following arterial gene transfer of vascular endothelial growth factor in a rabbit model of hindlimb ischemia
Biochemical and Biophysical Research Communications, ISSN: 0006291X
Satoshi Takeshita; Lawrence Weir; Dongfen Chen; Lu P. Zheng; Reimer Riessen; Christophe Bauters; James F. Symes; Napoleone Ferrara; Jeffrey M. Isner
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The cellular patterns of BDNF and trkB expression suggest multiple roles of BDNF during Xenopus visual system development
Developmental Biology, ISSN: 00121606
Susana Cohen-Cory; Escandon; Scott E. Fraser
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Changes in body composition of human immunodeficiency virus-infected males receiving insulin-like growth factor I and growth hormone
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Ellis; Lee; Pivarnik; Julie Bukar; Gesundheit
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Ovarian steroid regulation of vascular endothelial growth factor in the human endometrium: Implications for angiogenesis during the menstrual cycle and in the pathogenesis of endometriosis
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Jan L. Shifren; Jennifer F. Tseng; Charles J. Zaloudek; Isabelle P. Ryan; Meng; Napoleone Ferrara; Robert B. Jaffe; Robert N. Taylor
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Structural stability of disulfide mutants of basic pancreatic trypsin inhibitor: A molecular dynamics study
Proteins: Structure, Function and Bioinformatics, ISSN: 08873585
Celia A. Schiffer; Wilfred F. Van Gunsteren
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