Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13101 - 13150 OF 15578 RESULTS

Identification of Gas6 as a growth factor for human Schwann cells
Journal of Neuroscience, ISSN: 02706474
Li; Jian Chen; Glenn Hammonds Jr.; Phillips; Armanini; Patrick M. Wood; Richard P. Bunge; Godowski; Mark X. Sliwkowski; Mather
View on Scopus
Growth regulation of human breast and ovarian tumor cells by heregulin: Evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness
Cancer Research, ISSN: 00085472
Gail D. Lewis; Julie A. Lofgren; Amy E. McMurtrey; Andrew Nuijens; Brian M. Fendly; Kenneth D. Bauer; Mark X. Sliwkowski
View on Scopus
Regulation of thrombopoietin levels by c-mpl - Mediated binding to platelets
Blood, ISSN: 00064971
Fielder; Austin L. Gurney; Stefanich; Marian; Mark Moore; Karen Carver-Moore; Frederic J. De Sauvage
View on Scopus
Protection against lethal Escherichia coli bacteremia in baboons (Papio anubis) by pretreatment with a 55-kDa TNF receptor (CD120a)-Ig fusion protein, Ro 45-2081
Journal of Immunology, ISSN: 00221767
Kimberly J. Van Zee; Lyle L. Moldawer; Hester S. A. Oldenburg; William A. Thompson; Sarah A. Stackpole; Walton J. Montegut; Michael A. Rogy; Carol Meschter; Harald Gallati; Claus-Dieter Schiller; Wolfgang F. Richter; Hansruedi Loetscher; Avi Ashkenazi; Steven M. Chamow; Florian M. Wurm; Steve E. Calvano; Stephen F. Lowry; Werner Lesslauer
View on Scopus
Analysis of heregulin-induced ErbB2 phosphorylation with a high-throughput kinase receptor activation enzyme-linked immunosorbant assay
Analytical Biochemistry, ISSN: 00032697
Michael D Sadick; Mark X. Sliwkowski; Andrew Nuijens; Bald; Nancy Y. Chiang; Julie A. Lofgren; Wai Lee T. Wong
View on Scopus
An integrated method to determine epithelial transport and bioactivity of oral drug candidates in vitro
Pharmaceutical Research, ISSN: 07248741
Rubas; Cromwell; Mrsny; Gladys S. Ingle; Kathleen A. Elias
View on Scopus
Aggregation of rhDNase occurred during the compression of KBr pellets used for FTIR spectroscopy
Pharmaceutical Research, ISSN: 07248741
Chan; Ongpipattanakul; Jacky Au-Yeung
View on Scopus
Identification of vascular endothelial growth factor determinants for binding KDR and FLT-1 receptors: Generation of receptor-selective VEGF variants by site-directed mutagenesis
Journal of Biological Chemistry, ISSN: 00219258
Keyt; Hung V. Nguyen; Lea Berleau; Carlos M. Duarte; Jeanie Park; Helen Chen; Napoleone Ferrara
View on Scopus
Participation of JAK and STAT proteins in growth hormone-induced signaling
Journal of Biological Chemistry, ISSN: 00219258
Yulong Han; Douglas W. Leaman; Diane Watling; Neil C. Rogers; Bernd Groner; Ian M. Kerr; William I. Wood; George R. Stark
View on Scopus
TAFII250 is a bipartite protein kinase that phosphorylates the basal transcription factor RAP74
Cell, ISSN: 00928674
Rivka Dikstein; Siegfried Ruppert; Robert Tjian
View on Scopus
Vascular endothelial growth factor-related protein: A ligand and specific activator of the tyrosine kinase receptor Flt4
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
James Lee; Gray; Jean Q. Yuan; Shiuh-Ming Luoh; Hava Avraham; William I. Wood
View on Scopus
The effect of variance function estimation on nonlinear calibration inference in immunoassay data
Biometrics, ISSN: 0006341X
Bruce A. Belanger; Davidian; Giltinan
View on Scopus
The quaking gene product necessary in embryogenesis and myelination combines features of RNA binding and signal transduction proteins
Nature Genetics, ISSN: 10614036
Tom A. Ebersole; Qi Chen; Monica J. Justice; Karen Artzt
View on Scopus
Transforming growth factor β1 induces angiogenesis in vivo with a threshold pattern
Laboratory Investigation, ISSN: 00236837
Luis F. Fajardo; Stavros D. Prionas; Helen H. Kwan; Joe Kowalski; Anthony C. Allison
View on Scopus
Reproductive toxicity testing of therapeutic biotechnology agents
Teratology, ISSN: 00403709
Judith W. Henck; Kim G. Hilbish; Mercedes A. Serabian; Joy A. Cavagnaro; Andrew G. Hendrickx; Narsingh D. Agnish; Ada H.C. Kung; Joyce Mordenti
View on Scopus
Critical amino acids in the lymphocyte function-associated antigen-1 I domain mediate intercellular adhesion molecule 3 binding and immune function
Journal of Experimental Medicine, ISSN: 00221007
Yvette Van Kooyk; Minke E. Binnerts; Caroline P. Edwards; Mark Champe; Berman; Carl G. Figdor; Bodary
View on Scopus
Expression and regulation of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in distinct avian motoneuron subsets
Journal of Neurobiology, ISSN: 00223034
Nitza Kahane; David L. Shelton; Chaya Kalcheim
View on Scopus
Systematic improvement of a chemically-defined protein-free medium for hybridoma growth and monoclonal antibody production
Journal of Biotechnology, ISSN: 01681656
Stoll; Mühlethaler; Von Stockar; Ian W. Marison
View on Scopus
IRAK: A kinase associated with the interleukin-1 receptor
Science, ISSN: 00368075
Zhaodan Cao; William J. Henzel; Xiong Gao
View on Scopus
Biological and immunological characterization of inhibin forms in human plasma
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Robertson; Burger; Sullivan; Cahir; Nigel P. Groome; Poncelet; Franchimont; Woodruff; Mather
View on Scopus
Decreased food intake does not completely account for adiposity reduction after ob protein infusion
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Nancy Levin; Nelson; Austin L. Gurney; Richard Vandleni; Frederic J. De Sauvage
View on Scopus
Strategies for manipulating apoptosis for cancer therapy with tumor necrosis factor and lymphotoxin
Journal of Cellular Biochemistry, ISSN: 07302312
Grace H.W. Wong; Roger L. Kaspar; Gary Zweiger; Carlson; Fong; Niloofar Ehsani; Gordon A. Vehar
View on Scopus
The Crystal Structure of the Extracellular Domain of Human Tissue Factor Refined to 1.7 Å Resolution
Journal of Molecular Biology, ISSN: 00222836
Yves A. Muller; Ultsch; De Vos
View on Scopus
HGF and HGF receptor expresion in the lacrimal gland
Investigative Ophthalmology and Visual Science, ISSN: 01460404
Mohan; Li; Weng; Bennett; Ralph H. Schwall; Wang; Tabor; Kim; Hargrave; Cuevas; Wilson
View on Scopus
Differential cardiac effects of growth hormone and insulin-like growth factor-1 in the rat: A combined in vivo and in vitro evaluation
Circulation, ISSN: 00097322
Antonio Cittadini; Hinrik Strömer; Sarah E. Katz; Ross Clark; Alan C. Moses; James P. Morgan; Pamela Douglas
View on Scopus
Tear Hepatocyte Growth Factor (HGF) production increases markedly after excimer laser photorefractive keratoplasty (PRK)
Investigative Ophthalmology and Visual Science, ISSN: 01460404
Qianwa Liang; Tervo; Vesaluoma; Bennett; Ralph H. Schwall; Marco Helena; Wilson
View on Scopus
Vascular endothelial growth factor promotes tumor dissemination by a mechanism distinct from its effect on primary tumor growth
Cancer Research, ISSN: 00085472
Ostap Melnyk; Shuman; K.Jin Kim
View on Scopus
Macrophage-mediated apoptosis in the developing mouse eye
Investigative Ophthalmology and Visual Science, ISSN: 01460404
Graciana Diez-Roux; Mark Labow; Horst Bluthman; Mark Moore; Richard Lang
View on Scopus
Isomerization of an aspartic acid residue in the complementarity-determining regions of a recombinant antibody to human IgE: Identification and effect on binding affinity
Biochemistry, ISSN: 00062960
Cacia; Rodney Keck; Presta; John Frenz
View on Scopus
A model for metal affinity protein precipitation
Journal of Colloid and Interface Science, ISSN: 00219797
Harish V. Iyer; Todd M. Przybycien
View on Scopus
Targeted disruption of the Stat1 gene in mice reveals unexpected physiologic specificity in the JAK-STAT signaling pathway
Cell, ISSN: 00928674
Marco A. Meraz; J. Michael White; Kathleen C. Sheehan; Bach; Scott J. Rodig; Anand S. Dighe; Daniel H. Kaplan; Riley; Andrew C. Greenlund; Dayle Campbell; Karen Carver-Moore; Raymond N. DuBois; Ross Clark; Michel Aguet; Schreiber
View on Scopus
High level secretion of a humanized bispecific diabody from Escherichia coli
Bio/Technology, ISSN: 0733222X
Zhu; Gerardo Zapata; Shalaby; Snedecor; Man Chert; Paul J. Carter
View on Scopus
Physiological regulation of early and late stages of megakaryocytopoiesis by thrombopoietin
Journal of Experimental Medicine, ISSN: 00221007
Frederic J. De Sauvage; Karen Carver-Moore; Shiuh-Ming Luoh; Anne Ryan; Mary Dowd; Dan L. Eaton; Mark Moore
View on Scopus
The in vivo bioactivity of vascular endothelial growth factor/vascular permeability factor is independent of N-linked glycosylation
Laboratory Investigation, ISSN: 00236837
Dirk H. Walter; Uli Hink; Takayuki Asahara; Eric Van Belle; Jeffrey Horowitz; Yukio Tsurumi; Richard L. Vandlen; Heinsohn; Keyt; Napoleone Ferrara; James F. Symes; Jeffrey M. Isner
View on Scopus
Electrophoretic separation of recombinant tissue-type plasminogen activator glycoforms: Validation issues for capillary isoelectric focusing methods
Electrophoresis, ISSN: 01730835
Kathy Moorhouse; Carina A. Rickel; Chen
View on Scopus
Cardiotrophin-1 displays early expression in the murine heart tube and promotes cardiac myocyte survival
Development (Cambridge), ISSN: 09501991
Zelin Sheng; Diane Pennica; William I. Wood; Kenneth R. Chien
View on Scopus
Identification of a hepatocyte growth factor autocrine loop in a murine mammary carcinoma
Cell Growth and Differentiation, ISSN: 10449523
Nader Rahimi; Eric Tremblay; Laura McAdam; Marg Park; Ralph H. Schwall; Bruce Elliott
View on Scopus
Multiple immune abnormalities in tumor necrosis factor and lymphotoxin-α double-deficient mice
International Immunology, ISSN: 09538178
Hans-Pietro Eugster; Matthias Müller; Urs Karrer; Bruce D. Car; Bruno Schnyder; Vicki M. Eng; Gaetane Woerly; Michel Le Hir; Franco Di Padova; Michel Aguet; Rolf M. Zinkernagel; Horst Bluethmann; Bernhard Ryffel
View on Scopus
Hypoxia-induced paracrine regulation of vascular endothelial growth factor receptor expression
Journal of Clinical Investigation, ISSN: 00219738
Edi Brogi; Gina Schatteman; Tiangen Wu; Elizabeth A. Kim; Lyuba Varticovski; Keyt; Jeffrey M. Isner
View on Scopus
Hematopoietic defects in mice lacking the sialomucin CD34
Blood, ISSN: 00064971
Jill Cheng; Baumhueter; Cacalano; Karen Carver-Moore; Harold Thibodeaux; Thomas; Hal E. Broxmeyer; Cooper; Hague; Mark Moore; Lasky
View on Scopus
Hematopoietic defects in mice lacking the sialomucin CD34
Blood, ISSN: 00064971
Jill Cheng; Baumhueter; Cacalano; Karen Carver-Moore; Harold Thibodeaux; Thomas; Hal E. Broxmeyer; Scott Cooper; Hague; Mark Moore; Lasky
View on Scopus
Vascular endothelial growth factor augments muscle blood flow and function in a rabbit model of chronic hindlimb ischemia
Journal of Cardiovascular Pharmacology, ISSN: 01602446
Walder; Carol J. Errett; Bunting; Peter Lindquist; John R. Ogez; Heinsohn; Napoleone Ferrara; G. Roger Thomas
View on Scopus
Pharmacokinetics and pharmacodynamics of TP-9201, a gpIIbIIIa antagonist, administered in combination with recombinant tissue-type plasminogen activator, heparin, and aspirin in beagles
Journal of Cardiovascular Pharmacology, ISSN: 01602446
Modi; Theresa Reynolds; Sharon A. Baughman; Deborah A. Thomas; Paasch; Susan Yvonne Smith
View on Scopus
Binding in the growth hormone receptor complex
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
James A. Wells
View on Scopus
Structure of the saponin adjuvant QS-21 and its base-catalyzed isomerization product by 1 H and natural abundance 13 C NMR spectroscopy
Carbohydrate Research, ISSN: 00086215
Neil E. Jacobsen; Wayne J. Fairbrother; Kensil; Lim; Deborah A. Wheeler; Powell
View on Scopus
Liquid-liquid emulsification by rotor/stator homogenization
Journal of Controlled Release, ISSN: 01683659
Maa; Chung C. Hsu
View on Scopus
Multicopy suppressors of prc mutant Escherichia coli include two HtrA (DegP) protease homologs (HhoAB), DksA, and a truncated rlpA
Journal of Bacteriology, ISSN: 00219193
Bass; Qimin Gu; Anthony Christen
View on Scopus
Flux measurements across Caco-2 monolayers may predict transport in human large intestinal tissue
Journal of Pharmaceutical Sciences, ISSN: 00223549
Rubas; Cromwell; Shahrokh; Villagran; Nguyen; Wellton; Tue H. Nguyen; Mrsny
View on Scopus
Penicillamine: An extractable chiral auxiliary providing excellent stereocontrol
Tetrahedron Asymmetry, ISSN: 09574166
Lutz S. Richter; Thomas Gadek
View on Scopus
Protection of MN-rgp120-immunized chimpanzees from heterologous infection with a primary isolate of human immunodeficiency virus type 1
Journal of Infectious Diseases, ISSN: 00221899
Berman; Murthy; Wrin; Vennari; Kathy Cobb; Eastman; Mark Champe; Nakamura; Donna Davison; Powell; Bussiere; Francis; Matthews; Timothy Gregory; John F. Obijeski
View on Scopus
© 2025 Genentech, Inc. All rights reserved. This site is intended for US residents only.