Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13601 - 13650 OF 15578 RESULTS

A single residue determines the distinct pharmacology of rat and human natriuretic peptide receptor-C
Journal of Biological Chemistry, ISSN: 00219258
Alfred M Engel; Schoenfeld; David G Lowe
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TRAP, the trp RNA-binding attenuation protein of Bacillus subtilis, is a multisubunit complex that appears to recognize G/UAG repeats in the trpEDCFBA and trpG transcripts
Journal of Biological Chemistry, ISSN: 00219258
Paul Babitzke; Stults; Steven J. Shire; Yanofsky
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Autoproteolytic activation of the mouse prohormone convertase MPC1
Biochemical and Biophysical Research Communications, ISSN: 0006291X
Goodman; Cornelia M. Gorman
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From Peptide to Non-Peptide. 1. The Elucidation of a Bioactive Conformation of the Arginine-Glycine-Aspartic Acid Recognition Sequence
Journal of the American Chemical Society, ISSN: 15205126 00027863
Robert S. McDowell; Thomas Gadek; Burdick; Peter L. Barker; Kathryn S. Chan; Clifford L. Ouan; Martin Struble; Maureen Tischler; Jeffrey Tom; Burnier; Nicholas J. Skelton; Eugene D. Thorsett; Thomas R. Webb
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From Peptide to Non-Peptide. 2. The de Novo Design of Potent, Non-Peptidal Inhibitors of Platelet Aggregation Based on a Benzodiazepinedione Scaffold
Journal of the American Chemical Society, ISSN: 15205126 00027863
Robert S. McDowell; Brent Blackburn; Thomas Gadek; Thomas E. Rawson; Mark E. Reynolds; Kirk D. Robarge; Todd C. Somers; Maureen Tischler; Lawrence R. McGee; Eugene D. Thorsett; Robert R. Webb II; Michael C. Venuti
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InfoTrac TFD: A microcomputer implementation of the transcription factor database TFD with a graphical user interface
Bioinformatics, ISSN: 13674803
Wolfgang G. Hoeck
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Expression of fucosylated antigens and α1,3 fucosyltransferases in human leukaemia cell lines
Glycobiology, ISSN: 09596658
Nancy E. Robinson; Theodora De Vries; Richard E. Davis; Cheryl L.M. Stults; Susan R. Watson; Dirk H. Van Den Eijnden; Bruce A. Macher
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Structural requirements for adhesion of soluble recombinant murine vascular cell adhesion molecule-1 to α4β1
Journal of Cell Biology, ISSN: 00219525
Renz; Chiu; Susan Jones; Judy Fox; K.Jin Kim; Presta; Sherman Fong
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Reduced concentration of serum growth hormone-binding protein in children with idiopathic short stature
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Carlsson; Kenneth M. Attie; Peter G. Compton; Roderick V. Vitangcol; Thomas J. Merimee
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Cloning and expression of a soluble sialidase from chinese hamster ovary cells: Sequence alignment similarities to bacterial sialidases
Glycobiology, ISSN: 09596658
Ferrari; Reed J. Harris; Warner
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Structural requirements for adhesion of soluble recombinant murine vascular cell adhesion molecule-1 to α4β1
Journal of Cell Biology, ISSN: 00219525
Renz; Chiu; Susan Jones; Judy Fox; K.Jin Kim; Presta; Fong
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Identification and characterization of SPRK, a novel src-homology 3 domain-containing proline-rich kinase with serine/threonine kinase activity
Journal of Biological Chemistry, ISSN: 00219258
Kathleen A. Gallo; Melanie R Mark; David T. Scadden; Zhengyu Wang; Qimin Gu; Godowski
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Subunit dynamics in Escherichia coli preprotein translocase
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
John C. Joly; Marilyn R. Leonard; William T. Wickner
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Signaling steps involving the cytoplasmic domain of the interferon-γ receptor α-subunit are not species-specific
Journal of Biological Chemistry, ISSN: 00219258
Ruth Böhni; Silvio Hemmi; Michel Aguet
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Regulation of the avidity of integrin α4β7 by the β7 cytoplasmic domain
Journal of Biological Chemistry, ISSN: 00219258
Crowe; Chiu; Sherman Fong; Irving L. Weissman
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Regulation of the avidity of integrin α4β7 by the β7 cytoplasmic domain
Journal of Biological Chemistry, ISSN: 00219258
Crowe; Chiu; Fong; Irving L. Weissman
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A novel bioactivity assay for monoclonal antibodies directed against IgE
Journal of Immunological Methods, ISSN: 00221759
David Tai Wai Fei; John Lowe; Paula Jardieu
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The erbB3 gene product is a receptor for heregulin
Journal of Biological Chemistry, ISSN: 00219258
Kermit L. Carraway III; Mark X. Sliwkowski; Robert W. Akita; Jill V. Platko; Pamela M. Guy; Andrew Nuijens; John Diamonti; Richard L. Vandlen; Lewis C. Cantley; Richard A. Cerione
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Cloning and characterization of HTK, a novel transmembrane tyrosine kinase of the EPH subfamily
Journal of Biological Chemistry, ISSN: 00219258
Brian D. Bennett; Zhengyu Wang; Wun-Jing Kuang; Anlai Wang; Jerome E. Groopman; David V. Goeddel; David T. Scadden
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Farnesyl-diphosphate synthase is localized in peroxisomes
Journal of Biological Chemistry, ISSN: 00219258
Skaidrite Krisans; Johan Ericsson; Peter A. Edwards; Gilbert-Andre Keller
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A reinvestigation of a synthetic peptide (TrPepz) designed to mimic trypsin
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
James A. Wells; Wayne J. Fairbrother; Jacek Otlewski; Michael Laskowski Jr.; Burnier
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In Vitro Selection of Zinc Fingers with Altered DNA-Binding Specificity
Biochemistry, ISSN: 15204995 00062960
Andrew C. Jamieson; Sung-Hou Kim; James A. Wells
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A novel isotope labeling protocol for bacterially expressed proteins
Journal of Biomolecular NMR, ISSN: 09252738 15735001
Dorothea Reilly; Wayne J. Fairbrother
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Acute rejection of marrow grafts in mice: Dependence on and independence of functional TCR in the rejection process
Journal of Immunology, ISSN: 00221767
Kazuyoshi Takeda; Mark Moore; Gunther Dennert
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In vivo administration of insulin-like growth factor-I stimulates primary B lymphopoiesis and enhances lymphocyte recovery after bone marrow transplantation
Journal of Immunology, ISSN: 00221767
Paula Jardieu; Ross Clark; Deborah L. Mortensen; Kenneth Dorshkind
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Failure to demonstrate long-lived MHC saturation both in vitro and in vivo: Implications for therapeutic potential of MHC-blocking peptides
Journal of Immunology, ISSN: 00221767
Glenn Y. Ishioka; Luciano Adorini; Jean-Charles Guery; Federico C. A. Gaeta; Renee LaFond; Jeff Alexander; Powell; Alessandro Sette; Howard M. Grey
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The stoichiometry of growth hormone-binding protein complexes in human plasma: Comparison with cell surface receptors
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Gerhard Baumann; Henry B. Lowman; Moises Mercado; James A. Wells
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Production of the RANTES chemokine in delayed-type hypersensitivity reactions: Involvement of macrophages and endothelial cells
Journal of Experimental Medicine, ISSN: 00221007
Odile Devergne; Anne Marfaing-Koka; Thomas J. Schall; Marie-Bénédicte Leger-Ravet; Michael D Sadick; Michel Peuchmaur; Marie-Claude Crevon; Tim Kim; Pierre Galanaud; Dominique Emilie
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Electronic resources in human-computer interaction
Conference on Human Factors in Computing Systems - Proceedings,
Gary Perlman; Jakob Nielsen; John Morris; Brian Shackel
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Peptidomimetic inhibitors of Ras farnesylation
Chemistry and Biology, ISSN: 10745521
James C. Marsters Jr.; Robert S. McDowelll; Mark E. Reynolds; Todd C. Somers; Joseph L. Goldstein; Michael S. Brown; Guy L. James
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Vascular endothelial growth factor: A cytokine modulating endothelial function in rheumatoid arthritis
Journal of Immunology, ISSN: 00221767
Alisa Koch; Lisa A. Harlow; G. Kenneth Haines; Edward P. Amento; Elaine N. Unemori; Wei Lee Wong; Richard M. Pope; Napoleone Ferrara
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Vascular endothelial growth factor: A cytokine modulating endothelial function in rheumatoid arthritis
Journal of Immunology, ISSN: 00221767
Alisa Koch; Lisa A. Harlow; G. Kenneth Haines; Edward P. Amento; Elaine N. Unemori; Wai Lee T. Wong; Richard M. Pope; Napoleone Ferrara
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Neurotrophin 3 stimulates the differentiation of motoneurons from avian neural tube progenitor cells
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Lea Averbuch-Heller; Merav Pruginin; Nitza Kahane; Tsoulfas; Parada; Rosenthal; Chaya Kalcheim
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Neurotrophin 4/5 is a trophic factor for mammalian facial motor neurons
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Vassilis E. Koliatsos; Michelle H. Cayouette; Lucy R. Berkemeier; Richard E. Clatterbuck; Donald L. Price; Rosenthal
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Retention and degradation of proteins containing an uncleaved glycosylphosphatidylinositol signal
Journal of Biological Chemistry, ISSN: 00219258
Mark C. Field; Paul Moran; Wenlu Li; Gilbert-Andre Keller; Caras
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Mono-N-alkylation of anthranilamides via quinazolinones. An efficient synthesis of G5598, a benzodiazepine dione gpIIbIIIa antagonist
Tetrahedron Letters, ISSN: 00404039
Robert R. Webb II; Peter L. Barker; Mark Baier; Mark E. Reynolds; Kirk D. Robarge; Brent Blackburn; Maureen Tischler; Kenneth J Weese
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Ecotin Is a Potent Anticoagulant and Reversible Tight-Binding Inhibitor of Factor Xa
Biochemistry, ISSN: 15204995 00062960
Jana L. Seymour; Robert N. Lindquist; Dennis; Lazarus; Moffat; Yansura; Dorothea Reilly; Wessinger
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Protein Folding Activities of Escherichia coli Protein Disulfide Isomerase
Biochemistry, ISSN: 15204995 00062960
John C. Joly; James R. Swartz
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A faster-acting and more potent form of tissue plasminogen activator
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Keyt; Nicholas F. Paoni; Refino; Lea Berleau; Hung V. Nguyen; Alice M. Chow; Lai; Luis Peña; Cheryl Pater; John R. Ogez; Etcheverry; David Botstein; William F. Bennett
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Signal transduction versus buffering activity in Ca2+-binding proteins
Nature Structural Biology, ISSN: 10728368
Nicholas J. Skelton; Johan Kördel; Mikael Akke; Sture Forsén; Walter J. Chazin
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Regulation of neurotrophin receptors during the maturation of the mammalian visual system
Journal of Neuroscience, ISSN: 02706474
Karen L. Allendoerfer; Robert J. Cabelli; Escandon; David R. Kaplan; Nikolics; Carla J. Shatz
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Mice lacking nerve growth factor display perinatal loss of sensory and sympathetic neurons yet develop basal forebrain cholinergic neurons
Cell, ISSN: 00928674
Crowley; Spencer; Merry Nishimura; Grace Chan; Sharon Pitts-Meek; Mark P. Armaninl; Lanway H. Ling; McMahon; David L. Shelton; Levinson; Phillips
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Expression of the duffy antigen in K562 cells: Evidence that it is the human erythrocyte chemokine receptor
Journal of Biological Chemistry, ISSN: 00219258
Asok Chaudhuri; Valerie Zbrzezna; Julia Polyakova; A. Oscar Pogo; Joseph Hesselgesser; Richard Horuk
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Neutralization of IL-8 inhibits neutrophil influx in a rabbit model of endotoxin-induced pleurisy
Journal of Immunology, ISSN: 00221767
V. Courtney Broaddus; Alice M. Boylan; John M. Hoeffel; K.Jin Kim; Michael D Sadick; Anan Chuntharapai; Hébert
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Two new procedures for the introduction of benzyl-type protecting groups for thiols
Tetrahedron Letters, ISSN: 00404039
Lutz S. Richter; James C. Marsters Jr.; Thomas Gadek
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Vascular endothelial growth factor is induced in response to transforming growth factor-β in fibroblastic and epithelial cells
Journal of Biological Chemistry, ISSN: 00219258
Liisa Pertovaara; Arja Kaipainen; Tuija Mustonen; Arto Orpana; Napoleone Ferrara; Olli Saksela; Kari Alitalo
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Modification of CD4 Immunoadhesin with Monomethoxy poly (ethylene glycol) Aldehyde via Reductive Alkylation
Bioconjugate Chemistry, ISSN: 15204812 10431802
Steven M. Chamow; Peers; Timothy P. Kogan; Michael C. Venuti; Thomas Gadek; Reed J. Harris; Joyce Mordenti; Steven Shak; Avi Ashkenazi
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Characterization of Humanized Anti-TAC, an Antibody Directed Against the Interleukin 2 Receptor, Using Electrospray Ionization Mass Spectrometry by Direct Infusion, LC/MS, and MS/MS
Analytical Chemistry, ISSN: 15206882 00032700
Derf A. Lewis; Andrew W. Guzzetta; William S. Hancock; Maureen Costello
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Functional analysis of the cysteine residues of activin A
Molecular Endocrinology, ISSN: 08888809
Anthony J. Mason
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Genetically engineered proinsulin constitutively processed and secreted as mature, active insulin
Journal of Biological Chemistry, ISSN: 00219258
Debyra J. Groskreutz; Mark X. Sliwkowski; Cornelia M. Gorman
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