Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13651 - 13700 OF 15578 RESULTS

February 15, 1994

Neutralizing monoclonal antibodies to human IL-8 receptor A map to the NH2-terminal region of the receptor

Journal of Immunology, ISSN: 00221767

Anan Chuntharapai; James Lee; Burnier; William I. Wood; Hébert; Jin Kim

February 15, 1994

Fas antigen and p55 TNF receptor signal apoptosis through distinct pathways

Journal of Immunology, ISSN: 00221767

Grace H.W. Wong; David V. Goeddel

February 1, 1994

Cis,cis-Muconate Lactonizing Enzyme from Trichosporon cutaneum: Evidence for a Novel Class of Cycloisomerases in Eucaryotes

Biochemistry, ISSN: 15204995 00062960

Paul Mazur; Wolfgang A. Pieken; Scott R. Budihas; Suzanne E. Williams; Susan Wong; John W. Kozarich

February 1, 1994

Protein Sorting by High Performance Liquid Chromatography. 2. Separation of Isophosphorylates of Recombinant Human DNase I on a Polyethylenimine Column

Analytical Chemistry, ISSN: 15206882 00032700

John Frenz; Quan; Cacia; Democko; Robert L. Bridenbaugh; McNerney

February 1, 1994

Cis,cis-Muconate Lactonizing Enzyme from Trichosporon cutaneum: Evidence for a Novel Class of Cycloisomerases in Eucaryotes

Biochemistry, ISSN: 15204995 00062960

Paul Mazur; Wolfgang A. Pieken; Scott R. Budihas; Suzanne E. Williams; Susan C. Wong; John W. Kozarich

January 28, 1994

Cloning of FRK, a novel human intracellular SRC-like tyrosine kinaseencoding gene

Gene, ISSN: 03781119

James Lee; Zhengyu Wang; Shiuh-Ming Luoh; William I. Wood; David T. Scadden

January 14, 1994

Identification and characterization of a novel tyrosine kinase from megakaryocytes

Journal of Biological Chemistry, ISSN: 00219258

Brian D. Bennett; Sally Cowley; Shuxian Jiang; Roanna London; Bijia Deng; Jadwiga Grabarek; Jerome E. Groopman; David V. Goeddel; Hava Avraham

January 4, 1994

Structure from function: Screening structural models with functional data

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Jin; Fred E. Cohen; James A. Wells

January 1, 1994

The X-ray structure of a growth hormone-prolactin receptor complex

Nature, ISSN: 00280836

Somers; Ultsch; De Vos; Anthony A. Kossiakoff

January 1, 1994

In vitro megakaryocytopoietic and thrombopoietic activity of c-mpl ligand (TPO) on purified murine hematopoietic stem cells

Blood, ISSN: 00064971

Francis C. Zeigler; Frederic J. De Sauvage; Widmer; Gilbert-Andre Keller; Christopher J. Donahue; Schreiber; Malloy; Hass; Dan L. Eaton; William Matthews

January 1, 1994

Rac translocates independently of the neutrophil NADPH oxidase components p47(phox) and p67(phox). Evidence for its interaction with flavocytochrome b558

Journal of Biological Chemistry, ISSN: 00219258

Heyworth; Benjamin P. Bohl; Bokoch; John T. Curnutte

January 1, 1994

Sialomucin ligands for selectins: a new family of cell adhesion molecules.

Princess Takamatsu symposia,

Lasky

January 1, 1994

Evaporation of Aqueous Aerosols Produced by Jet Nebulizers: Effects on Particle Size and Concentration of Solution in the Droplets

Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung, ISSN: 15579026 08942684

Phipps; Gonda

January 1, 1994

Humanized Monoclonal Antibodies

Annual Reports in Medicinal Chemistry, ISSN: 00657743

Presta

January 1, 1994

Chinese hamster ovary cells contain transcriptionally active full-length type C proviruses

Journal of Virology, ISSN: 0022538X

Yolanda S. Lie; Elicia M. Penuel; Mari-Anne L. Low; Nguyen; Jocelyn O. Mangahas; Anderson; Christos J. Petropoulos

January 1, 1994

Approaches to analysis of aggregates and demonstrating mass balance in pharmaceutical protein (basic fibroblast growth factor) formulations

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Shahrokh; Stratton; Eberlein; Y. John Wang

January 1, 1994

Report on the Genetic Stability Symposium. April 10-12, 1991. West Coast Chapter, Parenteral Drug Association.

Developments in biological standardization, ISSN: 03015149

Robert L. Garnick; Helder

January 1, 1994

New techniques in protein chemistry.

Developments in biological standardization, ISSN: 03015149

O'Connor; Rodney Keck; Reed J. Harris; Field

January 1, 1994

Mammalian nonsense codons can be cis effectors of nuclear mRNA half-life

Molecular and Cellular Biology, ISSN: 02707306

Phillip Belgrader; Jiu Cheng; Xianbo Zhou; Lori S. Stephenson; Lynne E. Maquat

January 1, 1994

Interferon-α and induction of type I diabetes

Biomedicine and Pharmacotherapy, ISSN: 07533322

Tracy Stewart

January 1, 1994

Islet expression of interferon-α precedes diabetes in both the BB rat and streptozotocin-treated mice

Immunity, ISSN: 10747613

Huang; Hultgren; Noel Dybdal; Stewart

January 1, 1994

Use of polymerase chain reaction (PCR) in the development of a recombinant organism.

Developments in biological standardization, ISSN: 03015149

Helder; Utter

January 1, 1994

Activation of TNF‐R1 receptor in the presence of copper kills TNF resistant CEM leukemic T cells

Journal of Cellular Physiology, ISSN: 10974652 00219541

H. Garrett Wada; Katherine S. Fok; Brian M. Fendly; Nancy Y. Chiang; Howard H. Sussman

January 1, 1994

Dissecting the energetics of an antibody‐antigen interface by alanine shaving and molecular grafting

Protein Science, ISSN: 1469896X 09618368

Jin; James A. Wells

January 1, 1994

Consistency and stability of recombinant fermentations.

Developments in biological standardization, ISSN: 03015149

Wiebe; Stuart E. Builder

January 1, 1994

Chapter 23 Analysis of Intracellular Proteins

Methods in Cell Biology, ISSN: 0091679X

Kenneth D. Bauer; Jacobberger

January 1, 1994

Neurotrophin‐4/5 Promotes Survival and Differentiation of Rat Striatal Neurons Developing in Culture

European Journal of Neuroscience, ISSN: 14609568 0953816X

Hans R. Widmer; Franz Hefti

January 1, 1994

Large scale, in situ isolation of periplasmic IGF-I from E. coli

Bio/Technology, ISSN: 0733222X

Hart; Philip M. Lester; David H. Reifsnyder; John R. Ogez; Stuart E. Builder

January 1, 1994

Deafferentation removes calretinin immunopositive terminals, but does not induce degeneration of calbindin D‐28k and parvalbumin expressing neurons in the hippocampus of adult rats

Journal of Neuroscience Research, ISSN: 10974547 03604012

Klaus D. Beck; Franz Hefti; Hans R. Widmer

January 1, 1994

Mice devoid of interferon regulatory factor 1 (IRF-1) show normal expression of type I interferon genes

EMBO Journal, ISSN: 02614189

Luiz F. L. Reis; Heinz Ruffner; Gerlinde Stark; Michel Aguet; Charles Weissmann

January 1, 1994

One-day northern blotting for detection of mRNA: NDGA inhibits the induction of MnSOD mRNA by agonists of type 1 TNF receptor

Methods in Enzymology, ISSN: 15577988 00766879

Grace H.W. Wong; David V. Goeddel

January 1, 1994

Neurotrophic factor therapy for nervous system degenerative diseases

Journal of Neurobiology, ISSN: 10974695 00223034

Franz Hefti

January 1, 1994

Identification of the major sites of phosphorylation in IGF binding protein‐3

Journal of Cellular Biochemistry, ISSN: 10974644 07302312

Wolfgang G. Hoeck; Mukku

January 1, 1994

Placenta growth factor. Potentiation of vascular endothelial growth factor bioactivity, in vitro and in vivo, and high affinity binding to Flt-1 but not to Flk-1/KDR

Journal of Biological Chemistry, ISSN: 00219258

John E. Park; Helen Chen; Jane Winer; Houck; Napoleone Ferrara

January 1, 1994

The solution structure of melanoma growth stimulating activity

Journal of Molecular Biology, ISSN: 00222836

Wayne J. Fairbrother; Dorothea Reilly; Timothy J. Colby; Joseph Hesselgesser; Richard Horuk

January 1, 1994

Treatment of myocardial infarction in the United States (1990 to 1993): Observations from the National Registry of Myocardial Infarction

Circulation, ISSN: 00097322

William J. Rogers; Laura J. Bowlby; Nisha C. Chandra; William J. French; Joel M. Gore; Costas Lambrew; R. Michael Rubison; Alan J. Tiefenbrunn; W.Douglas Weaver

January 1, 1994

Effect of environment on insulin‐like growth factor I refolding selectivity

Biotechnology and Applied Biochemistry, ISSN: 14708744 08854513

Hart RA; Giltinan DM; Lester PM; Reifsnyder; Ogez JR; Builder SE

January 1, 1994

Induction of apoptosis in the murine liver with recombinant human activin a

Hepatology, ISSN: 15273350 02709139

James R. Hully; Chang; Ralph H. Schwall; Widmer; Timothy G. Terrell; Nancy Gillett

January 1, 1994

Analysis of two-dimensional gel proteins by mass spectrometry and microsequencing

Methods, ISSN: 10959130 10462023

William J. Henzel; Christopher Grimley; James H. Bourell; Todd M. Billeci; Susan C. Wong; Stults

January 1, 1994

Cryptic nature of envelope V3 region epitopes protects primary monocytotropic human immunodeficiency virus type 1 from antibody neutralization

Journal of Virology, ISSN: 0022538X

Dumith Chequer Bou-Habib; Gregory Roderiquez; Tamás Oravecz; Berman; Paolo Lusso; Michael A. Norcross

January 1, 1994

Recombinant vgr-1/BMP-6-expressing tumors induce fibrosis and endochondral bone formation in vivo

Journal of Cell Biology, ISSN: 00219525

Stephen E. Gitelman; Michael S. Kobrin; Jian-Qin Ye; Alfredo R. Lopez; Angela Lee; Rik Derynck

January 1, 1994

Postcapillary venule endothelial cells in kidney express a multispecific chemokine receptor that is structurally and functionally identical to the erythroid isoform, which is the duffy blood group antigen

Journal of Clinical Investigation, ISSN: 00219738

Hadley; Zhao-Hai Lu; Kazimiera Wasniowska; Alvin W. Martin; Pelper; Joseph Hesselgesser; Richard Horuk

January 1, 1994

Introns are cis effectors of the nonsense-codon-mediated reduction in nuclear mRNA abundance

Molecular and Cellular Biology, ISSN: 02707306

Jiu Cheng; Phillip Belgrader; Xianbo Zhou; Lynne E. Maquat

January 1, 1994

Mutations in the promoter region of the gene for gp91-phox in X-linked chronic granulomatous disease with decreased expression of cytochrome b558

Journal of Clinical Investigation, ISSN: 00219738

Peter E. Newburger; David G. Skalnik; Penelope J. Hopkins; Elizabeth A. Eklund; John T. Curnutte

January 1, 1994

Regional deposition of saline aerosols of different tonicities in normal and asthmatic subjects

European Respiratory Journal, ISSN: 09031936

Phipps; Gonda; Anderson; Bailey; Bautovich

January 1, 1994

Regional deposition of nebulized hypodense nonisotonic solutions in the human respiratory tract

European Respiratory Journal, ISSN: 09031936

Chan; Phipps; Gonda; Cook; Fulton; Young; Bautovich

January 1, 1994

Effects of recombinant human growth hormone on metabolic indices, body composition, and bone turnover in healthy elderly women

Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X

Leah Holloway; Gail E. Butterfield; Hintz; Gesundheit; Robert Marcus

January 1, 1994

The effect of systemically administered recombinant human nerve growth factor in healthy human subjects

Annals of Neurology, ISSN: 15318249 03645134

Brent G. Petty; David R. Cornblath; Bruce T. Adornato; Vinay Chaudhry; Charles Flexner; Matthew Wachsman; Sinicropi; Louis E. Burton; Peroutka

January 1, 1994

Application of a variable direction hysteresis minimization approach in describing the central nervous system pharmacodynamic effects of alfentanil in rabbits

Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549

Modi; Veng-Pedersen

January 1, 1994

Production of an atrial natriuretic peptide variant that is specific for type A receptor

EMBO Journal, ISSN: 02614189

Cunningham; David G Lowe; Bing Li; Brian D. Bennett; James A. Wells

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