Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13751 - 13800 OF 15578 RESULTS

January 1, 1994

Quality of life in patients with limited small-cell carcinoma of the lung receiving chemotherapy with or without radiation therapy, for cancer and leukemia group B

Psychotherapy and Psychosomatics, ISSN: 14230348 00333190

Tim A. Ahles; Peter M. Silberfarb; Amy Chen Rundle; Jimmie C. Holland; Alice B. Kornblith; George P. Canellos; Mark R. Green; Michael C. Perry

January 1, 1994

Diketopiperazine formation and N‐terminal degradation in recombinant human growth hormone

International Journal of Peptide and Protein Research, ISSN: 13993011 03678377

John E. Battersby; William S. Hancock; Eleanor Canova-Davis; Oeswein; O'ONNOR

January 1, 1994

Pharmacokinetics and Tissue Distribution of Recombinant Human Transforming Growth Factor Beta1 After Topical and Intravenous Administration in Male Rats

Pharmaceutical Research, ISSN: 1573904X 07248741

Zioncheck; Chen; Richardson; Marina Mora-Wor; Catherine Lucas; Lewis; Green; Joyce Mordenti

January 1, 1994

Benzodiazepine peptidomimetic inhibitors of farnesyltransferase

Bioorganic and Medicinal Chemistry, ISSN: 09680896

James C. Marsters Jr.; Robert S. McDowell; Mark E. Reynolds; David A. Oare; Todd C. Somers; Mark S. Stanley; Thomas E. Rawson; Martin Struble; Burdick; Kathryn S. Chan; Charles M. Duarte; Kenneth J. Paris; Jeffrey Tom; Dairian T. Wan; Yingchun Xue; John P. Bumier

January 1, 1994

Issues with Biotechnology Products in Toxicologic Pathology

Toxicologic Pathology, ISSN: 15331601 01926233

Timothy G. Terrell; Green

January 1, 1994

Identification of succinimide sites in proteins by N‐terminal sequence analysis after alkaline hydroxylamine cleavage

Protein Science, ISSN: 1469896X 09618368

Kwong; Reed J. Harris

January 1, 1994

Inhibins, activins, their binding proteins and receptors: Interactions underlying paracrine activity in the testis

Molecular and Cellular Endocrinology, ISSN: 03037207

Alison Moore; Lynne Krummen; Mather

January 1, 1994

Infection with pseudomonas cepacia in chronic granulomatous disease: Role of nonoxidative killing by neutrophils in host defense

Journal of Infectious Diseases, ISSN: 15376613 00221899

David P. Speert; Mason Bond; Richard C. Woodman; John T. Curnutte

January 1, 1994

The interleukin-8-receptor family: From chemokines to malaria

Immunology Today, ISSN: 01675699

Richard Horuk

January 1, 1994

The crystal structure of affinity-matured human growth hormone at 2 Å resolution

Journal of Molecular Biology, ISSN: 00222836

Ultsch; Somers; Anthony A. Kossiakoff; De Vos

January 1, 1994

In vitro selection from protein and peptide libraries

Trends in Biotechnology, ISSN: 01677799

Clackson; James A. Wells

January 1, 1994

A survey of furin substrate specificity using substrate phage display

Protein Science, ISSN: 1469896X 09618368

Matthews; Goodman; Cornelia M. Gorman; James A. Wells

January 1, 1994

Multiple mechanisms are responsible for altered expression of gap junction genes during oncogenesis in rat liver

Journal of Cell Science, ISSN: 00219533

Mark J. Neveu; James R. Hully; Karlee L. Babcock; Elliot L. Hertzberg; Bruce J. Nicholson; David L. Paul; Pitot

January 1, 1994

Assays for recombinant proteins: A problem in non‐linear calibration

Statistics in Medicine, ISSN: 10970258 02776715

Giltinan; Davidian

January 1, 1994

Panel discussion on vaccine development to meet U.S. and international needs. Perspectives on national and global HIV vaccine development: Potential ways to reduce impediments for biopharmaceutical product development

AIDS Research and Human Retroviruses, ISSN: 08892229

John F. Obijeski

January 1, 1994

Antibiotic overkill of trauma victims?

American Journal of Surgery, ISSN: 00029610

Dimitri Hadjiminas; William G. Cheadle; David A. Spain; Mark A. Wilson; Alicia Short; Karen M. Starko; Betty J. Harris; David H. Livingston; Jorge L. Rodriguez

January 1, 1994

Functions of brain-derived neurotrophic factor, insulin-like growth factor-I and basic fibroblast growth factor in the development and maintenance of dopaminergic neurons

Progress in Neurobiology, ISSN: 03010082

Klaus D. Beck

January 1, 1994

Adhesion Mediated by Intercellular Adhesion Molecule 1 Attenuates the Potency of Antibodies That Block HIV-1 gp160-Dependent Syncytium Formation

AIDS Research and Human Retroviruses, ISSN: 19318405 08892229

Berman; Nakamura

January 1, 1994

Modelling the deposition of inhaled powdered drug aerosols

Journal of Aerosol Science, ISSN: 00218502

Clark; Mike Egan

January 1, 1994

Probing the conformation of protein (bFGF) precipitates by fluorescence spectroscopy

Journal of Pharmaceutical and Biomedical Analysis, ISSN: 07317085

Shahrokh; Eberlein; Y. John Wang

January 1, 1994

The human photoreceptor membrane guanylyl cyclase, RetGC, is present in outer segments and is regulated by calcium and a soluble activator

Neuron, ISSN: 08966273

Alexander M. Dizhoor; David G Lowe; Elena V. Olshevskaya; Richard Laura; James B. Hurley

January 1, 1994

Administration of an anti-IgE antibody inhibits CD23 expression and IgE production in vivo

Immunology, ISSN: 00192805

Haak-Frendscho; Robbins; Lyon; Robert L. Shields; Jeff Hooley; Schoenhoff; Paula Jardieu

January 1, 1994

Towards an immunotherapy for p185(HER2) overexpressing tumors

Advances in Experimental Medicine and Biology, ISSN: 00652598

Paul J. Carter; Maria L. Rodrigues; Gail D. Lewis; Figari; Shalaby

January 1, 1994

Phenobarbital Removal Characteristics of Three Brands of Activated Charcoals: A System Analysis Approach

Pharmaceutical Research, ISSN: 1573904X 07248741

Modi; Veng-Pedersen; Dale Eric Wurster; Mary J. Berg; Dorothy D. Schottelius

January 1, 1994

Engineering an interfacial zinc site to increase hormone-receptor affinity

Chemistry and Biology, ISSN: 10745521

Matthews; James A. Wells

January 1, 1994

Pharmaco-toxicological expert report on recombinant human deoxyribonuclease I (Pulmozyme(TM) ; rhDNase)

Human and Experimental Toxicology, ISSN: 01445952

Green

January 1, 1994

Distribution of Inhaled Aerosols in the Respiratory Tract

Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung, ISSN: 15579026 08942684

Sweeney; Ultman

January 1, 1994

X‐ray structures of fragments from binding and nonbinding versions of a humanized anti‐CD18 antibody: Structural indications of the key role of VH residues 59 to 65

Proteins: Structure, Function and Bioinformatics, ISSN: 10970134 08873585

Eigenbrot; Gonzalez; Mayeda; Paul J. Carter; Winifred Werther; Hotaling; Judy Fox; Jeremy Kessler

January 1, 1994

Structural elements which govern the resistance of intestinal tissues to compound transport

Materials Research Society Symposium Proceedings, ISSN: 02729172

Rubas; Cronwell; Thomas Gadek; Narindray; Mrsny

January 1, 1994

Kunitz domain inhibitors of tissue factor-Factor VIIa. II. Potent and specific inhibitors by competitive phage selection

Journal of Biological Chemistry, ISSN: 00219258

Dennis; Lazarus

January 1, 1994

Kunitz domain inhibitors of tissue factor-Factor VIIa. I. Potent inhibitors selected from libraries by phage display

Journal of Biological Chemistry, ISSN: 00219258

Dennis; Lazarus

January 1, 1994

The contribution of open extremity fractures to infection in multiply injured patients

Injury, ISSN: 00201383

Naziri; William G. Cheadle; David H. Livingston; Jorge L. Rodriguez; Karen M. Starko; Hiram C. Polk

January 1, 1994

Assessment of aerosol delivery systems for recombinant human deoxyribonuclease

S.T.P. Pharma Sciences, ISSN: 11571489

Cipolla; Clark; Chan; Gonda; Steven J. Shire

January 1, 1994

Development of effective therapy for Alzheimer's disease based on neurotrophic factors

Neurobiology of Aging, ISSN: 01974580

Franz Hefti

January 1, 1994

Identification and characterization of batk, a predominantly brain‐specific non‐receptor protein tyrosine kinase related to Csk

Journal of Neuroscience Research, ISSN: 10974547 03604012

Sophia S. Kuo; Paul Moran; Gripp; Armanini; Phillips; Goddard; Caras

January 1, 1994

Inhibition of TNF by a TNF receptor immunoadhesin: Comparison to an anti- TNF monoclonal antibody

Journal of Immunology, ISSN: 00221767

Haak-Frendscho; Scot A. Marsters; Joyce Mordenti; Brady; Nancy Gillett; Chen; Avi Ashkenazi

January 1, 1994

Protection against rat endotoxic shock by p55 tumor necrosis factor (tnf) receptor immunoadhesin: Comparison with anti-tnf monoclonal antibody

Journal of Infectious Diseases, ISSN: 15376613 00221899

Hongkui Jin; Renhui Yang; Scot A. Marsters; Bunting; Florian M. Wurm; Steven M. Chamow; Avi Ashkenazi

January 1, 1994

Neurotrophic‐4/5 is a survival factor for embryonic midbrain dopaminergic neurons in enriched cultures

Journal of Neuroscience Research, ISSN: 10974547 03604012

Mary Hynes; Kris Poulsen; Armanini; Lucy R. Berkemeier; Phillips; Rosenthal

January 1, 1994

TGFβ2 and TGFβ3 are potent survival factors for midbrain dopaminergic neurons

Neuron, ISSN: 08966273

Kris Poulsen; Armanini; Robert D. Klein; Mary Hynes; Phillips; Rosenthal

January 1, 1994

Validation of a Variable Direction Hysteresis Minimization Pharmacodynamic Approach: Cardiovascular Effects of Alfentanil

Pharmaceutical Research, ISSN: 1573904X 07248741

Modi; Veng-Pedersen

January 1, 1994

Do antiidiotypic antibodies mimic antigen?

Research in Immunology, ISSN: 09232494

Amzel; Garcia; Desiderio

January 1, 1994

Major Degradation Products of Basic Fibroblast Growth Factor: Detection of Succinimide and Iso-aspartate in Place of Aspartate15

Pharmaceutical Research, ISSN: 1573904X 07248741

Shahrokh; Eberlein; Doug Buckley; Paranandi; Aswad; Stratton; Ron Mischak; Y. John Wang

January 1, 1994

ELISA for the neuropeptide degrading endopeptidase 3.4.24.11 in human serum and leukocytes

Peptides, ISSN: 01969781

Minzhong Zhang; Jochen Niehus; Thomas Schnellbacher; Silke Müller; Kristof Graf; Klaus D. Schultz; Claus R. Baumgarten; Catherine Lucas; Gert Kunkel

January 1, 1994

Pharmacokinetics and pharmacodynamics of recombinant proteins and peptides

Journal of Controlled Release, ISSN: 01683659

Modi

January 1, 1994

Feasibility Study on Spray-Drying Protein Pharmaceuticals: Recombinant Human Growth Hormone and Tissue-Type Plasminogen Activator

Pharmaceutical Research, ISSN: 1573904X 07248741

Mumenthaler; Chung C. Hsu; Rodney Pearlman

January 1, 1994

Cytokine regulation of lactate dehydrogenase-elevating virus: inhibition of viral replication by interferon-γ

Antiviral Research, ISSN: 01663542

William A. Cafruny; Sarahann E. Bradley; James J. Broen; Grace H.W. Wong

January 1, 1994

The Met Repressor‐Operator Complex: DNA Recognition by β‐Strands

Annals of the New York Academy of Sciences, ISSN: 17496632 00778923

Somers; Rafferty; PHILLIPS; Strathdee; He; McNALLY; Manfield; Navratil; Old; Saint-Girons; Stockley; Phillips

January 1, 1994

Immunological effects of insulin-like growth factor-I - Enhancement of immunoglobulin synthesis

Clinical and Experimental Immunology, ISSN: 00099104

Robbins; McCabe; Scheiner; Strasser; Ross Clark; Paula Jardieu

January 1, 1994

Effect of Recombinant Human Insulin-like Growth Factor I and Early Total Parenteral Nutrition on Immune Depression Following Severe Head Injury

Archives of Surgery, ISSN: 15383644 00040010

Kenneth A. Kudsk; Christine Mowatt Larssen; Julie Bukar; Timothy Fabian; Sherryl Oellerich; Daniel L. Dent; Rex Brown

January 1, 1994

Agrin-like proteins of the neuromuscular junction

Neurochemistry International, ISSN: 01970186

László Patthy; Nikolics

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