Genentech: Publications

January 1, 1992

Activin-A as an intraovarian modulator: Actions, localization, and regulation of the intact dimer in human ovarian cells

Journal of Clinical Investigation, ISSN: 00219738

Jaron Rabinovici; Susan J. Spencer; Nicola Doldi; Paul C. Goldsmith; Ralph H. Schwall; Robert B. Jaffe

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January 1, 1992

Monoclonal Antibodies to the Extracellular Domain of HIV-1IIIB gp160 that Neutralize Infectivity, Block Binding to CD4, and React with Diverse Isolates

AIDS Research and Human Retroviruses, ISSN: 19318405 08892229

Nakamura; Randal A. Byrn; Rosenthal; James P. Porter; Hobbs; Riddle; Eastman; Dowbenko; Timothy Gregory; Brian M. Fendly; Berman

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January 1, 1992

Three-dimensional structure of an angiotensin II-fab complex at 3 Å: Hormone recognition by an anti-idiotypic antibody

Science, ISSN: 00368075

Garcia; Pierre M. Ronco; Pierre J. Verroust; Axel T. Brünger; Amzel

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January 1, 1992

In vitro ligand binding of125I-recombinant human activin a to the female rat brain

Endocrinology, ISSN: 19457170 00137227

Lyn B. Jakeman; Mather; Woodruff

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January 1, 1992

In vivo import of firefly luciferase into the glycosomes of Trypanosoma brucei and mutational analysis of the C-terminal targeting signal

Molecular Biology of the Cell, ISSN: 10591524

Sommer; Qi-Lin Cheng; Gilbert-Andre Keller; Ching C. Wang

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January 1, 1992

Characterization of the Saccharomyces Golgi complex through the cell cycle by immunoelectron microscopy

Molecular Biology of the Cell, ISSN: 10591524

Preuss; Jon Mulholland; Alex Franzusoff; Nava Segev; David Botstein

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January 1, 1992

Development of humanized bispecitic antibodies reactive with cytotoxic lymphocytes and tumor cells overexpressing the HER2 protooncogene

Journal of Experimental Medicine, ISSN: 15409538 00221007

Shalaby; Shepard; Presta; Maria L. Rodrigues; Peter C. L. Beverley; Marc Feldmann; Paul J. Carter

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January 1, 1992

Antibody engineering

Current Opinion in Biotechnology, ISSN: 09581669

Presta

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January 1, 1992

Antibody engineering

Current Opinion in Structural Biology, ISSN: 0959440X

Presta

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January 1, 1992

Tetrapeptide inhibitors of protein farnesyltransferase: Ammo-terminal substitution in phenylalanine-containing tetrapeptides restores farnesylation

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Michael S. Brown; Joseph L. Goldstein; Kenneth J. Paris; Burnier; James C. Marsters Jr.

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January 1, 1992

Assignment of the Aliphatic 1H and 13C Resonances of the Bacillus Subtilis Glucose Permease IIA Domain Using Double- and Triple-Resonance Heteronuclear Three-Dimensional NMR Spectroscopy

Biochemistry, ISSN: 15204995 00062960

Mark Ranee; Peter E. Wright; Wayne J. Fairbrother; Arthur G. Palmer III; Jonathan Reizer; Milton H. Saier Jr.

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January 1, 1992

Crystal Structure of the Kringle 2 Domain of Tissue Plasminogen Activator at 2.4-Å. Resolution

Biochemistry, ISSN: 15204995 00062960

De Vos; Ultsch; Robert F. Kelley; Anthony A. Kossiakoff; Kaillathe Padmanabhan; Alexander Tulinsky; Mary L. Westbrook

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January 1, 1992

Involvement of zinc in binding of hGH to the prolactin receptor

Biomedicine and Pharmacotherapy, ISSN: 07533322

Wells

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January 1, 1992

Peptide mapping for detecting variants in protein products.

Developments in biological standardization, ISSN: 03015149

Robert L. Garnick

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January 1, 1992

Binding sites for vascular endothelial growth factor are localized on endothelial cells in adult rat tissues

Journal of Clinical Investigation, ISSN: 00219738

Lyn B. Jakeman; Jane Winer; Bennett; Anthony Altar; Napoleone Ferrara

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January 1, 1992

The vascular endothelial growth factor proteins: Identification of biologically relevant regions by neutralizing monoclonal antibodies

Growth Factors, ISSN: 08977194

K.Jin Kim; Bing Li; Houck; Jane Winer; Napoleone Ferrara

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January 1, 1992

Isolation and characterization of two safflower oleoyl-acyl carrier protein thioesterase cDNA clones

Plant Physiology, ISSN: 00320889

Deborah S. Knutzon; Janice L. Bleibaum; Janet Nelsen; Jean C. Kridl; Gregory A. Thompson

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January 1, 1992

Involvement of endogenous tumor necrosis factor α and transforming growth factor β during induction of collagen type II arthritis in mice

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Thorbecke; Shah; Chin-Hung Leu; Kuruvilla; Hardison; Michael A. Palladino

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January 1, 1992

Random PCR mutagenesis screening of secreted proteins by direct expression in mammalian cells

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Glenn C. Rice; David V. Goeddel; Cachianes; John D. Woronicz; Ellson Y. Chen; Steven R. Williams; Leung

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January 1, 1992

Quadruplex structure of d(G3T4G3) stabilized by K+ or Na+ is an asymmetric hairpin dimer

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Scaria; Steven J. Shire; Richard H. Shafer

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January 1, 1992

The amino terminus of nerve growth factor is involved in the interaction with the receptor tyrosine kinase p140(trkA)

Journal of Biological Chemistry, ISSN: 00219258

Philipp Kahle; Louis E. Burton; Charles H. Schmelzer; Cornelia Hertel

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January 1, 1992

A single amino-acid difference confers major pharmacological variation between human and rodent 5-HT1B receptors

Nature, ISSN: 00280836

Donna Oksenberg; Scot A. Marsters; Brian F. O'Dowd; Hui Jin; Sona Havlik; Peroutka; Avi Ashkenazi

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January 1, 1992

Identification of actin and HSP 70 as cyclosporin A binding proteins by photoaffinity labeling and fluorescence displacement assays

Journal of Biological Chemistry, ISSN: 00219258

Marcia L. Moss; Palmer; Petr Kuzmič; Brian E. Dunlap; William J. Henzel; James L. Kofron; William S. Mellon; Catherine A. Royer; Daniel H. Rich

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January 1, 1992

Biochemical Characterization of Recombinant Human Nerve Growth Factor

Journal of Neurochemistry, ISSN: 14714159 00223042

Charles H. Schmelzer; Louis E. Burton; Wai-Pan Chan; Evelyn Martin; Cornelia M. Gorman; Eleanor Canova-Davis; Victor Ling; Mary B. Sliwkowski; Glynis McCray; Jonathan A. Briggs; Tue H. Nguyen; Gian D. Polastri

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January 1, 1992

A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs

Science, ISSN: 00368075

Matthew J. Hart; Yoshiro Maru; Leonard; Owen N. Witte; Tony Evans; Richard A. Cerione

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January 1, 1992

Prohormone convertase-1 will process prorelaxin, a member of the insulin family of hormones

Molecular Endocrinology, ISSN: 19449917 08888809

David Marriott; Beth Gillece-Castro; Cornelia M. Gorman

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January 1, 1992

Treatment of systemic sclerosis with recombinant interferon‐γ. A phase I/II clinical trial

Arthritis and Rheumatism, ISSN: 15290131 00043591

Bruce Freundlich; Sergio A. Jimenez; Virginia D. Steen; Thomas A. Medsger Jr.; Michelle Szkolnicki; Howard S. Jaffe

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January 1, 1992

Comparative Study of Photodissociation and Surface-Induced Dissociation by Laser Desorption Fourier Transform Mass Spectrometry

Analytical Chemistry, ISSN: 15206882 00032700

John A. Castoro; Charles L. Wilkins; Lydia M. Nuwaysir; Carl F. Ijames

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January 1, 1992

Identification of an E-selectin region critical for carbohydrate recognition and cell adhesion

Journal of Cell Biology, ISSN: 00219525

David V. Erbe; Barry A. Wolitzky; Presta; Norton; Robert J. Ramos; Daniel K. Burns; John M. Rumberger; B. N. Narasinga Rao; Carroll Foxall; Brian K. Brandley; Lasky

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January 1, 1992

Modulation of airway inflammation in cystic fibrosis: In vivo suppression of interleukin-8 levels on the respiratory epithelial surface by aerosolization of recombinant secretory leukoprotease inhibitor

Journal of Clinical Investigation, ISSN: 00219738

McElvaney; Nakamura; Birrer; Hébert; Wai Lee T. Wong; Merlyn Alphonso; Baker; Catalano; Crystal

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January 1, 1992

In vitro inhibitory effect of IL-8 and other chemoattractants on neutrophil-endothelial adhesive interactions

Journal of Immunology, ISSN: 00221767

Francis W. Luscinskas; Jeanne-Marie Kiely; Han Ding; Obin; Hébert; Baker; Gimbrone Jr.

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January 1, 1992

Loss of gene function through rapid mitotic cycles in the Drosophila embryo

Nature, ISSN: 00280836

Mike Rothe; Michael Pehl; Heike Taubert; Herbert Jäckle

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January 1, 1992

Activin-a inhibits progesterone production by macaque luteal cells in culture

Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X

John D. Brannian; Woodruff; Mather; Richard L. Stouffer

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January 1, 1992

Signal transduction by the platelet integrin αiibβ3: Induction of calcium oscillations required for protein-tyrosine phosphorylation and ligand-induced spreading of stably transfected cells

Molecular Biology of the Cell, ISSN: 10591524

Pelletier; Bodary; Levinson

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January 1, 1992

The effect of anorexia nervosa and refeeding on growth hormone-binding protein, the insulin-like growth factors (IGFs), and the IGF-binding proteins

Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X

Debra R. Counts; Harry Gwirtsman; Carlsson; Michael Lesem

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January 1, 1992

Characterization of two high affinity human interleukin-8 receptors

Journal of Biological Chemistry, ISSN: 00219258

James Lee; Richard Horuk; Glenn C. Rice; Bennett; Camerato; William I. Wood

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January 1, 1992

Structural consequences of mutation

Current Opinion in Biotechnology, ISSN: 09581669

Eigenbrot; Anthony A. Kossiakoff

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January 1, 1992

Variability of conformations at crystal contacts in BPTI represent true low‐energy structures: Correspondence among lattice packing and molecular dynamics structures

Proteins: Structure, Function and Bioinformatics, ISSN: 10970134 08873585

Anthony A. Kossiakoff; Michael Randal; Guenot; Charles Eignebrot

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January 1, 1992

Altered metabolic and adhesive properties and increased tumorigenesis associated with increased expression of transforming growth factor β1

Journal of Cell Biology, ISSN: 00219525

Arrick; Alfredo R. Lopez; Fred Elfman; Reinhard Ebner; Caroline H. Damsky; Rik Derynck

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January 1, 1992

K‐252b Selectively Potentiates Cellular Actions and trk Tyrosine Phosphorylation Mediated by Neurotrophin‐3

Journal of Neurochemistry, ISSN: 14714159 00223042

Beat Knüsel; David R. Kaplan; Winslow; Rosenthal; Louis E. Burton; Klaus D. Beck; Stuart Rabin; Nikolics; Franz Hefti

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January 1, 1992

Effects of recombinant insulin-like growth factor-I (IGF-I) and growth hormone on serum IGF-binding proteins in calorically restricted adults

Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X

Simon C. J. Young; Louis E. Underwood; Abbie Celniker; David R. Clemmons

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January 1, 1992

Editorial overview

Current Opinion in Structural Biology, ISSN: 0959440X

Raymond Salemme; James A. Wells

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January 1, 1992

Transcription and recombination of the murine RS element

Journal of Immunology, ISSN: 00221767

Loren E. Daitch; Mark Moore; Denise M. Persiani; Jeannine M. Durdik; Erik Selsing

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January 1, 1992

Conformational Effects in the Reversed-Phase Chromatographic Behavior of Recombinant Human Growth Hormone (rhGH) and N-Methionyl Recombinant Human Growth Hormone (Met-hGH)

Analytical Chemistry, ISSN: 15206882 00032700

Peter Oroszlan; Wicar; Shiaw-Lin Wu; Karger; Glen Teshima; Wu; William S. Hancock

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January 1, 1992

An isoform of protein disulfide isomerase isolated from chronic myelogenous leukemia cells alters complex formation between nuclear proteins and regulatory regions of interferon-inducible genes

Journal of Biological Chemistry, ISSN: 00219258

Johnson; William J. Henzel; Albert Deisseroth

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January 1, 1992

Polyethylene glycol enhanced refolding of bovine carbonic anhydrase B. Reaction stoichiometry and refolding model

Journal of Biological Chemistry, ISSN: 00219258

Cleland; Hedgepeth; Daniel I. C. Wang

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January 1, 1992

Effects of recombinant human insulin-like growth factor-I (rhIGF-I) on total and free IGF-I concentrations, IGF-binding proteins, and glycemic response in humans

Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X

Steven A. Lieberman; Julie Bukar; Chen; Abbie Celniker; Peter G. Compton; Cook; Albu; Andrew J. Perlman; Andrew R. Hoffman

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January 1, 1992

Neutralization of multiple laboratory and clinical isolates of human immunodeficiency virus type 1 (HIV-1) by antisera raised against gp120 from the MN isolate of HIV-1

Journal of Virology, ISSN: 0022538X

Berman; Matthews; Riddle; Mark Champe; Hobbs; Nakamura; Jennifer Mercer; Eastman; Catherine Lucas; Alphonse J. Langlois; Florian M. Wurm; Timothy Gregory

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January 1, 1992

α-Isoenzyme of alcohol dehydrogenase from monkey liver. Cloning, expression, mechanism, coenzyme, and substrate specificity

Journal of Biological Chemistry, ISSN: 00219258

Light; Dennis; Ian J. Forsythe; Liu; Green; Darla Ann Kratzer; Bryce V. Plapp

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January 1, 1992

Rational design of potent antagonists to the human growth hormone receptor

Science, ISSN: 00368075

Fuh; Cunningham; Rikiro Fukunaga; Shigekazu Nagata; David V. Goeddel; James A. Wells

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