Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 14251 - 14300 OF 15578 RESULTS

January 1, 1992

Photolabelling of Salmonella typhimurium LT2 sialidase: Identification of a peptide with a predicted structural similarity to the active sites of influenza-virus sialidases

Biochemical Journal, ISSN: 02646021

Warner; Reed J. Harris; Robert S. McDowell; Vimr

January 1, 1992

Engineering a humanized bispecific F(ab')2 fragment for improved binding to T cells

International Journal of Cancer, ISSN: 00207136

Maria L. Rodrigues; Shalaby; Winifred Werther; Presta; Paul J. Carter

January 1, 1992

Characterization of the recombinant human receptor for Escherichia coli heat-stable enterotoxin

Journal of Biological Chemistry, ISSN: 00219258

Frederic J. De Sauvage; Richard Horuk; Bennett; Quan; Burnier; David V. Goeddel

January 1, 1992

Antiviral activity of tumor necrosis factor (TNF) is signaled through the 55-kDa receptor, type I TNF

Journal of Immunology, ISSN: 00221767

Grace H.W. Wong; Louis A. Tartaglia; Lee; David V. Goeddel

January 1, 1992

Radioiodination of the active site of tissue plasminogen activator: A method for radiolabeling serine proteases with tyrosylprolylarginyl chloromethyl ketone

Analytical Biochemistry, ISSN: 10960309 00032697

Keyt; Lea Berleau; Hung V. Nguyen; William F. Bennett

January 1, 1992

Human recombinant transforming growth factor-β1 modulation of biochemical and cellular events in healing of ulcer wounds

Journal of Investigative Dermatology, ISSN: 15231747 0022202X

Theresa L. Chen; Rebecca L. Bates; Yvette Xu; Arthur J. Ammann; Steven Beck

January 1, 1992

Permeability Characteristics of Various Intestinal Regions of Rabbit, Dog, and Monkey

Pharmaceutical Research, ISSN: 1573904X 07248741

Nancy Jezyk; Rubas; George M. Grass

January 1, 1992

Regulation of growth of normal ovarian epithelial cells and ovarian cancer cell lines by transforming growth factor-β

American Journal of Obstetrics and Gynecology, ISSN: 00029378

Andrew Berchuck; Gus Rodriguez; George Olt; Regina Whitaker; Matthew P. Boente; Arrick; Daniel L. Clarke-Pearson; Robert C. Bast Jr.

January 1, 1992

Rapid evolution of peptide and protein binding properties in vitro

Current Opinion in Structural Biology, ISSN: 0959440X

James A. Wells; Henry B. Lowman

January 1, 1992

Growth hormone and renal glutamine and glutamate handling

Journal of the American Society of Nephrology, ISSN: 10466673

Welbourne; Horton; Cronin

January 1, 1992

Selecting: Interpreters of cell-specific carbohydrate information during inflammation

Science, ISSN: 00368075

Lasky

January 1, 1992

Molecular cloning of a retina-specific membrane guanylyl cyclase

Neuron, ISSN: 08966273

Andrew W. Shyjan; Frederic J. De Sauvage; Nancy Gillett; David V. Goeddel; David G Lowe

January 1, 1992

Rapid evolution of peptide and protein binding properties in vitro

Current Opinion in Biotechnology, ISSN: 09581669

James A. Wells; Henry B. Lowman

January 1, 1992

A zymogenic tissue plasminogen activator variant: The Phe305→ His mutation suppresses fibrin(ogen) stimulated plasminogen activation by one chain t-PA

Fibrinolysis and Proteolysis, ISSN: 02689499

Deborah L. Higgins; Young; Powers; Anderson

January 1, 1992

Comparison of second messenger formation in human keratinocytes following stimulation with epidermal growth factor and bradykinin

Second Messengers and Phosphoproteins, ISSN: 08957479

Johnson; King; Vera B. Morhenn

January 1, 1992

Pharmaceutics of protein drugs

Journal of Pharmacy and Pharmacology, ISSN: 00223573

Rodney Pearlman; Tue H. Nguyen

January 1, 1992

Conservation of the kinaselike regulatory domain is essential for activation of the natriuretic peptide receptor guanylyl cyclases

Molecular and Cellular Biology, ISSN: 02707306

Koller; Frederic J. De Sauvage; David G Lowe; David V. Goeddel

January 1, 1992

Human growth hormone and extracellular domain of its receptor: Crystal structure of the complex

Science, ISSN: 00368075

De Vos; Ultsch; Anthony A. Kossiakoff

January 1, 1992

A simple method for the preparation of single-stranded polydeoxynucleotides of desired length

BioTechniques, ISSN: 07366205

White; Drossman; Drayna

January 1, 1992

Cloning, expression during development, and evidence for release of a trophic factor for ciliary ganglion neurons

Neuron, ISSN: 08966273

Leung; Annette S. Parent; Cachianes; Esch; James N. Coulombe; Nikolics; Felix P. Eckenstein; Rae Nishi

January 1, 1992

Synthesis and biological activity of a 5,6-substituted teleocidin

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

Robert R. Webb II; Michael C. Venuti

January 1, 1992

The synthesis of a phorbol 12,13-bis-lactone

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

Thomas E. Rawson; Timothy P. Kogan

January 1, 1992

Human recombinant soluble decay accelerating factor inhibits complement activation in vitro and in vivo

Journal of Immunology, ISSN: 00221767

Paul Moran; Beasley; Gorrell; Martin; Gribling; Henry J. Fuchs; Nancy Gillett; Louis E. Burton; Caras

January 1, 1992

Integration and stability of CHO amplicons containing plasmid sequences

Developments in biological standardization, ISSN: 03015149

Florian M. Wurm; Maria G. Pallavicini; Arathoon

January 1, 1992

Strontium-90 induced bone tumours in beagle dogs: Effects of route of exposure and dose rate

International Journal of Radiation Biology, ISSN: 09553002

Nancy Gillett; Pool; Taylor; Muggenburg; Boecker

January 1, 1992

Nucleotide sequence selection for increased expression of heterologous genes in Escherichia coli

Methods, ISSN: 10959130 10462023

Yansura; Laura C. Simmons

January 1, 1992

Structure-function analysis of hepatocyte growth factor: Identification of variants that lack mitogenic activity yet retain high affinity receptor binding

EMBO Journal, ISSN: 02614189

Lokker; Melanie R Mark; Luis; Bennett; Robbins; Baker; Godowski

January 1, 1992

Molecular structural basis of ligand selectivity for 5-HT2 versus 5-HT1C cortical receptors

Naunyn-Schmiedeberg's Archives of Pharmacology, ISSN: 14321912 00281298

Pierce; Joanne Y. Kim; Peroutka

January 1, 1992

Paracrine Regulation of Reproductive Function by Inhibin and Activin

Proceedings of the Society for Experimental Biology and Medicine, ISSN: 15353699 00379727

Mather; Woodruff; Lynne Krummen

January 1, 1992

The cytoplasmic domain of tissue factor is phosphorylated by a protein kinase C-dependent mechanism

Journal of Biological Chemistry, ISSN: 00219258

Zioncheck; Roy; Gordon A. Vehar

January 1, 1992

The gene encoding human plasma carboxypeptidase B (CPB2) resides on chromosome 13

Genomics, ISSN: 10898646 08887543

Siao Ping Tsai; Drayna

January 1, 1992

O-linked fucose is present in the first epidermal growth factor domain of factor XII but not protein C

Journal of Biological Chemistry, ISSN: 00219258

Reed J. Harris; Victor Ling; Spellman

January 1, 1992

Truncated and native insulinlike growth factor I enhance mucosal adaptation after jejunoileal resection

Gastroenterology, ISSN: 00165085

Jon A. Vanderhoof; Robert H. McCusker; Ross Clark; Hamid Mohammadpour; Darcy J. Blackwood; Richard F. Harty; Jung H.Y. Park

January 1, 1992

Phase I study of continuous-infusion soluble CD4 as a single agent and in combination with oral dideoxyinosine therapy in children with symptomatic human immunodeficiency virus infection

Journal of Pediatrics, ISSN: 00223476

Robert N. Husson; Yoomie Chung; Joyce Mordenti; Karina M. Butler; Chen; A-M. Duliege; Pim Brouwers; Paul Jarosinski; Brigitta U. Mueller; Arthur J. Ammann; Philip A. Pizzo

January 1, 1992

Immunodominant structures of human growth hormone identified by homolog-scanning mutagenesis

Molecular Immunology, ISSN: 01615890

Joseph R. Weber; Nelson; Cunningham; James A. Wells; Sherman Fong

January 1, 1992

Use of rapid serial sampling of creatine kinase MB for very early detection of myocardial infarction in patients with acute chest pain

American Heart Journal, ISSN: 10976744 00028703

Michael M. Marin; Sam L. Teichman

January 1, 1992

Pituitary follicular cells secrete an inhibitor of aortic endothelial cell growth: Identification as leukemia inhibitory factor

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Napoleone Ferrara; Jane Winer; William J. Henzel

January 1, 1992

Human natriuretic peptide receptor-A guanylyl cyclase. Hormone cross- linking and antibody reactivity distinguish receptor glycoforms

Journal of Biological Chemistry, ISSN: 00219258

David G Lowe; Brian M. Fendly

January 1, 1992

The apolipoprotein(a) moiety of lipoprotein(a) interacts with the complement activation fragment iC3b but does not functionally affect C3 activation or degradation

Atherosclerosis, ISSN: 00219150

Paul S. Seifert; Iris Roth; Zioncheck

January 1, 1992

Utilization of homologous proteins to evaluate the safety of recombinant human proteins - case study: recombinant human interferon-gamma (rhIFN-γ)

Toxicology Letters, ISSN: 03784274

Green; Timothy G. Terrell

January 1, 1992

Virions of primary human immunodeficiency virus type 1 isolates resistant to soluble CD4 (sCD4) neutralization differ in sCD4 binding and glycoprotein gp120 retention from sCD4-sensitive isolates

Journal of Virology, ISSN: 0022538X

John P. Moore; Jane A. Mckeating; Yaoxing Huang; Avi Ashkenazi; David D. Ho

January 1, 1992

Relaxin binding in the rat heart atrium

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Phyllis L. Osheroff; Cronin; Julie A. Lofgren

January 1, 1992

Chemical heterogeneity as a result of hydroxylamine cleavage of a fusion protein of human insulin-like growth factor I

Biochemical Journal, ISSN: 02646021

Eleanor Canova-Davis; Eng; Mukku; David H. Reifsnyder; Charles V. Olson; Victor Ling

January 1, 1992

Biochemical properties of the 75-kDa tumor necrosis factor receptor. Characterization of ligand binding, internalization, and receptor phosphorylation

Journal of Biological Chemistry, ISSN: 00219258

Diane Pennica; Lam; Mize; Weber; Lewis; Brian M. Fendly; Michael T. Lipari; David V. Goeddel

January 1, 1992

Growth hormone augments superoxide anion secretion of human neutrophils by binding to the prolactin receptor

Journal of Clinical Investigation, ISSN: 00219738

Yung-Kang Fu; Sean Arkins; Germaine Fun; Cunningham; James A. Wells; Fong; Cronin; Robert Dantzer; Keith W. Kelley

January 1, 1992

A GDP dissociation inhibitor that serves as a GTPase inhibitor for the Ras-like protein CDC42Hs

Science, ISSN: 00368075

Matthew J. Hart; Yoshiro Maru; David Leonard; Owen N. Witte; Tony Evans; Richard A. Cerione

January 1, 1992

Identification of proteins binding to interferon-inducible transcriptional enhancers in hematopoietic cells

Journal of Biological Chemistry, ISSN: 00219258

Wedrychowski; William J. Henzel; Laurel Huston; Paslidis; Debra Ellerson; Michele McRae; David Seong; O. M. Zack Howard; Albert Deisseroth

January 1, 1992

Vascular endothelial growth factor induces interstitial collagenase expression in human endothelial cells

Journal of Cellular Physiology, ISSN: 10974652 00219541

Elaine N. Unemori; Napoleone Ferrara; Eugene A. Bauer; Edward P. Amento

January 1, 1992

Posttranslational modifications in the amino-terminal region of the large subunit of ribulose-1,5-bisphosphate carboxylase/oxygenase from several plant species

Plant Physiology, ISSN: 00320889

Robert L. Houtz; Loelle Poneleit; Samantha B. Jones; Malcolm Royer; Stults

January 1, 1992

The fms-like tyrosine kinase, a receptor for vascular endothelial growth factor

Science, ISSN: 00368075

Carlie De Vries; Escobedo; Hikaru Ueno; Houck; Napoleone Ferrara; Williams

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