Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 15251 - 15300 OF 15583 RESULTS

January 1, 1986

Immunopharmacology of tumor necrosis factors α and β

Trends in Pharmacological Sciences, ISSN: 01656147

Michael A. Palladino; Bryan S Finkle

January 1, 1986

Regulation of the chelatin promoter during the expression of human serum albumin or yeast phosphoglycerate kinase in yeast

Bio/Technology, ISSN: 0733222X

Etcheverry; Forrester; Ronald A. Hitzeman

January 1, 1986

Regulation of pro-opiomelanocortin gene transcription in individual cell nuclei

Science, ISSN: 00368075

Robert T. Fremeau Jr.; James R. Lundblad; Dolan B. Pritchett; Josiah N. Wilcox; James L. Roberts

January 1, 1986

A Sensitive Radioimmunoprecipitation Assay for the Detection of Antibody to Recombinant Human Gamma-Interferon: Comparison to a Bioassay Neutralization Test

Journal of Interferon Research, ISSN: 15577465 01978357

Chen; Vincent R. Anicetti; Toni Klassen; Berthold; Gaby Zahn; Wert Jr.; Geier; Andrew J.S. Jones

January 1, 1986

What is protein engineering?

Protein Engineering, Design and Selection, ISSN: 17410134 17410126

Wetzel

January 1, 1986

Specificity of trna charging in tyr-trna synthetase

Protein Engineering, Design and Selection, ISSN: 17410134 17410126

Wetzel

January 1, 1986

Intracellular assembly and packaging of hepatitis B surface antigen particles occur in the endoplasmic reticulum

Journal of Virology, ISSN: 0022538X

Patzer; Nakamura; Simonsen; Levinson; Brands

January 1, 1986

Saccharomyces cerevisiae secretes and correctly processes human interferon hybrid proteins containing yeast invertase signal peptides

Molecular and Cellular Biology, ISSN: 02707306

Chung N. Chang; Matteucci; Perry; Wulf; Christina Y. Chen; Ronald A. Hitzeman

January 1, 1986

Deoxynucleoside H-Phosphonate diester intermediates in the synthesis of internucleotide phosphate analogues

Tetrahedron Letters, ISSN: 00404039

Froehler

January 1, 1986

Nerve growth factor mRNA in peripheral and central rat tissues and in the human central nervous system: Lesion effects in the rat brain and levels in Alzheimer's disease

Molecular Brain Research, ISSN: 0169328X

Goedert; Fine; Hunt; Axel Ullrich

January 1, 1986

The cloning of factor VIII and the genetics of hemophilia A

Hospital Practice, ISSN: 87502836

Gordon A. Vehar; Lawn

January 1, 1986

A fortran implementation of univariate fourier series density estimation

Communications in Statistics: Simulation and Computation, ISSN: 15324141 03610918

Michael E. Tarter; William Freeman; Alan Hopkins

January 1, 1986

Novel form of transcription attenuation regulates expression of the Bacillus subtilis tryptophan operon

Journal of Bacteriology, ISSN: 00219193

Hidenori Shimotsu; Mitzi I. Kuroda; Yanofsky; Henner

January 1, 1986

Construction of a single-copy integration vector and its use in analysis of regulation of the trp operon of Bacillus subtilis

Gene, ISSN: 03781119

Shimotsu Hidenori; Henner

January 1, 1986

The organization and nucleotide sequence of the Bacillus subtilis hisH, tyrA and aroE genes

Gene, ISSN: 03781119

Henner; Louise Band; Gail W. Flaggs; Ellson Y. Chen

January 1, 1986

Identification of a missense mutation in the factor VIII gene of a mild hemophiliac

Science, ISSN: 00368075

Jane Gitschier; William I. Wood; Shuman; Lawn

January 1, 1986

Isolation of the gene and hypothalamic cDNA for the common precursor of gonadotropin-releasing hormone and prolactin release-inhibiting factor in human and rat

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Adelman; Anthony J. Mason; Hayflick; Peter H. Seeburg

January 1, 1986

Peripheral artery and bypass graft thrombolysis with recombinant human tissue-type plasminogen activator

Journal of Vascular Surgery, ISSN: 07415214

Robert A. Graor; Barbara Risius; Jess R. Young; Kevin Denny; Edwin G. Beven; Michael A. Geisinger; Norman R. Hertzer; Leonard P. Krajewski; Fred V. Lucas; Patrick J. O'Hara; William F. Ruschhaupt; Sheila Winton; Margaret G. Zelch; Grossbard

January 1, 1986

The oncogenic activation of human p21ras by a novel mechanism

Science, ISSN: 00368075

Walter; Clark; Levinson

January 1, 1986

[20]Protein dynamics investigated by neutron diffraction

Methods in Enzymology, ISSN: 15577988 00766879

Anthony A. Kossiakoff

January 1, 1986

Complementary DNA sequences of ovarian follicular fluid inhibin show precursor structure and homology with transforming growth factor-β

Obstetrical and Gynecological Survey, ISSN: 15339866 00297828

Anthony J. Mason; Hayflick; Nicholas Ling; Esch; Naoto Ueno; Shao-Yao Ying; Roger Guillemin; Hugh D. Niall; Peter H. Seeburg

January 1, 1986

Determination of 2-keto-l-gulonic and other ketoaldonic and aldonic acids produced by ketogenic bacterial fermentation

Analytical Biochemistry, ISSN: 10960309 00032697

Lazarus; Jana L. Seymour

January 1, 1986

Nucleoside h-phosphonates: Valuable intermediates in the synthesis of deoxyoligonucleotides

Tetrahedron Letters, ISSN: 00404039

Froehler; Matteucci

January 1, 1986

Modulation of Bacillus subtilis levansucrase gene expression by sucrose and regulation of the steady-state mRNA level by sacU and sacQ genes

Journal of Bacteriology, ISSN: 00219193

Hidenori Shimotsu; Henner

January 1, 1986

Methionyl human growth hormone and oxandrolone in Turner syndrome: Preliminary results of a prospective randomized trial

Journal of Pediatrics, ISSN: 00223476

Rosenfeld; Hintz; Ann J. Johanson; Jo Anne Brasel; Stephen Burstein; Chernausek; Teresa Clabots; James W. Frane; Ronald W. Gotlin; Joyce Kuntze; Barbara M. Lippe; Patrick C. Mahoney; Wayne V. Moore; Maria I. New; Saenger; Elizabeth Stoner; Virginia Sybert

January 1, 1986

H-Y intermediate phenotype in male pseudohermaphroditism

Journal of Pediatrics, ISSN: 00223476

Thomas A. Wilson; Stephen S. Wachtel; Stuart Howards; John Lininger; Ann J. Johanson

January 1, 1986

Normal and activated ras oncogenes and their encoded products

Trends in Genetics, ISSN: 01689525

Levinson

January 1, 1986

Human Luteinizing hormone-releasing hormone gene (LHRH) is located on short arm of chromosome 8 (region 8p11.2 → p21)

Somatic Cell and Molecular Genetics, ISSN: 07407750 15729931

Yang-Feng; Peter H. Seeburg; Uta Francke

January 1, 1986

Biochemical characterization of polypeptides encoded by mutated human Ha-ras1 genes

Molecular and Cellular Biology, ISSN: 02707306

Colby; Hayflick; Clark; Levinson

January 1, 1986

[35] In Situ cDNA;mRNA Hybridization: Development of Technique to Measure mRNA Levels in Individual Cells

Methods in Enzymology, ISSN: 15577988 00766879

Josiah N. Wilcox; Gee; James L. Roberts

January 1, 1986

Nucleotide sequence of the alkaline phosphatase gene of Escherichia coli

Gene, ISSN: 03781119

Chung Nan Chang; Kuang Wun-Jing; Ellson Y. Chen

January 1, 1986

Identification of the pleiotropic sacQ gene of Bacillus subtilis

Journal of Bacteriology, ISSN: 00219193

Yang; Ferrari; Ellson Y. Chen; Henner

January 1, 1986

Regulation of adenylate cyclase by β-melanotropin in the M2R melanoma cell line

Molecular and Cellular Endocrinology, ISSN: 03037207

Jeffrey E. Gerst; Josepha Sole; Mather; Yoram Salomon

January 1, 1986

The incorporation of a fluorescent probe into the active sites of one- and two-chain tissue-type plasminogen activator

Archives of Biochemistry and Biophysics, ISSN: 10960384 00039861

Deborah L. Higgins; M.Christine Lamb

January 1, 1986

[11] Large-scale production and recovery of human immune interferon

Methods in Enzymology, ISSN: 15577988 00766879

Robert Van Reis; Stuart E. Builder; Lubiniecki

January 1, 1986

Absorption enhancement of growth hormone from the gastrointestinal tract of rats

International Journal of Pharmaceutics, ISSN: 03785173

Moore; S.Anne Pletcher; Ross

January 1, 1986

In Vitro Biological Activities of Escherichia Coli-Derived Bovine Interferons-α, -β, and -γ

Journal of Interferon Research, ISSN: 15577465 01978357

Christine W. Czarniecki; Hamilton; Christopher Fennie; Ronald L. Wolf

January 1, 1986

Large-scale cell culture in biotechnology

Science, ISSN: 00368075

W. Robert Arathoon; Birch

January 1, 1986

Probing steric and hydrophobic effects on enzyme-substrate interactions by protein engineering

Science, ISSN: 00368075

David A. Estell; Graycar; Jeffrey V. Miller; Powers; Burnier; Ng; James A. Wells

January 1, 1986

Cell culture derived recombinant hbsag is highly immunogenic and protects chimpanzees from infection with hepatitis B virus

Bio/Technology, ISSN: 0733222X

Patzer; Nakamura; Robert D. Hershberg; Timothy Gregory; Crowley; Levinson; Eichberg

January 1, 1986

Serodiagnosis of antibodies to the human aids retrovirus with a bacterially synthesized ehv polypeptide

Bio/Technology, ISSN: 0733222X

Cirilo D. Cabradilla Jr.; Jerome E. Groopman; Joan Lanigan; Renz; Lasky; Capon

January 1, 1986

1. Primary Structure of Insulin and Insulin-like Growth Factor I Receptors

Journal of the Japan Diabetes Society, ISSN: 0021437X

Axel Ullrich; Gray; Collins; Ellson Y. Chen; TSUBOKAWA; Steven Jacobs; Yoko Fujita-Yamaguchi

December 17, 1985

Urea treatment allows dithiothreitol to release the binding subunit of the insulin receptor from the cell membrane: Implications for the structural organization of the insulin receptor

Biochemical and Biophysical Research Communications, ISSN: 10902104 0006291X

Grunfeld; Judy Kwan Shigenaga; Ramachandran

December 1, 1985

Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus

Nature, ISSN: 00280836

Mark A. Muesing; Smith; Cirilo D. Cabradilla Jr.; Charles V. Benton; Lasky; Capon

December 1, 1985

A phase I trial of recombinant gamma interferon in patients with cancer

Cancer Immunology, Immunotherapy, ISSN: 03407004 14320851

Kenneth A. Foon; Stephen A. Sherwin; Paul G. Abrams; Henry C. Stevenson; Pamela Holmes; Annette E. Maluish; Robert K. Oldham; Ronald B. Herberman

December 1, 1985

Activation of human polymorphonuclear neutrophil functions by interferon-γ and tumor necrosis factors

Journal of Immunology, ISSN: 00221767

Shalaby; Aggarwal; Rinderknecht; Svedersky; Bryan S Finkle; Michael A. Palladino

December 1, 1985

Topology of signal recognition particle receptor in endoplasmic reticulum membrane

Nature, ISSN: 00280836

Leander Lauffer; Pablo D. Garcia; Harkins; Lisa Coussens; Axel Ullrich; Peter Walter

December 1, 1985

Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells

Nature, ISSN: 00280836

Rik Derynck; Jarrett; Ellson Y. Chen; Eaton; Bell; Richard K. Assoian; Anita B. Roberts; Michael B. Sporn; David V. Goeddel

December 1, 1985

Cloning and expression in Escherichia coli of the cDNA for murine tumor necrosis factor

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Diane Pennica; Hayflick; Timothy S. Bringman; Michael A. Palladino; David V. Goeddel

December 1, 1985

Amplification, enhanced expression and possible rearrangement of EGF receptor gene in primary human brain tumours of glial origin

Nature, ISSN: 00280836

Towia A. Libermann; Harris R. Nusbaum; Nissim Razon; Richard Kris; Lax; Hermona Soreq; Nigel Whittle; Waterfield; Axel Ullrich; Schlessinger

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