Scientists / Publications

Publications

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DISPLAYING 5401 - 5450 OF 15390 RESULTS

Blinding properties of methods for supplying drug kits to investigational sites
Contemporary Clinical Trials Communications, ISSN: 24518654
Ron Yu; Daniel A. Coleman
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A novel design for randomized immuno-oncology clinical trials with potentially delayed treatment effects
Contemporary Clinical Trials Communications, ISSN: 24518654
Pei He; Zheng Su
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Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
Nature, ISSN: 14764687 00280836
Nobuhiko Kayagaki; Irma B. Stowe; Bettina L. Lee; Karen M. O'Rourke; Keith R. Anderson; Søren Warming; Trinna L. Cuellar; Benjamin Haley; Merone Roose-Girma; Qui Phung; Peter S. Liu; Jennie R. Lill; Hong Li; Jiansheng Wu; Sarah K. Kummerfeld; Juan Zhang; Wyne P. Lee; Scott J. Snipas; Guy S. Salvesen; Lucy X. Morris; Linda Fitzgerald; Yafei Zhang; Edward M. Bertram; Christopher C. Goodnow; Vishva M. Dixit
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Survival and Racial Differences of Non-Small Cell Lung Cancer in the United States Military
Journal of General Internal Medicine, ISSN: 15251497 08848734
Christina Brzezniak; Sacha Satram-Hoang; Hans-Peter Goertz; Carolina Reyes; Ashok Gunuganti; Christopher Gallagher; Corey A. Carter
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Inhibition of DYRK1A and GSK3B induces human β-cell proliferation
Nature Communications, ISSN: 20411723
Weijun Shen; Brandon Taylor; Qihui Jin; Van Nguyen-Tran; Shelly Meeusen; You-Qing Zhang; Anwesh Kamireddy; Austin Swafford; Andrew F. Powers; John Walker; John Lamb; Badry Bursalaya; Michael Didonato; George Harb; Minhua Qiu; Christophe Filippi; Lisa Deaton; Carolina N. Turk; Wilma L. Suarez-Pinzon; Yahu Liu; Xueshi Hao; Tingting Mo; Shanshan Yan; Jing Li; Ann E. Herman; Bernhard J. Hering; Tom Wu; Martin Seidel; Peter McNamara; Richard Glynne; Bryan A. Laffitte
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Interactions between Peptide and Preservatives: Effects on Peptide Self-Interactions and Antimicrobial Efficiency in Aqueous Multi-Dose Formulations
Pharmaceutical Research, ISSN: 1573904X 07248741
Heljo; Ross; Isidro E. Zarraga; Pappenberger; Hanns-Christian Mahler
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Prepregnancy Risk Factors for Preterm Birth and the Role of Maternal Nativity in a Low-Income, Hispanic Population
Maternal and Child Health Journal, ISSN: 15736628 10927875
Stephanie A. Leonard; Catherine M. Crespi; Denise Gee; Yuda Zhu; Shannon E. Whaley
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The Ro60 autoantigen binds endogenous retroelements and regulates inflammatory gene expression
Science, ISSN: 10959203 00368075
Hung; Pratt; Sundararaman; Towsend; Christina Chaivorapol; Tushar Bhangale; Robert R. Graham; Ward Ortmann; Criswell; Yeo; Timothy W. Behrens
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Kinome screen identifies PFKFB3 and glucose metabolism as important regulators of the insulin/insulin-like growth factor (IGF)-1 signaling pathway
Journal of Biological Chemistry, ISSN: 1083351X 00219258
Sophie Trefely; Poh-Sim Khoo; James R. Krycer; Rima Chaudhuri; Daniel J. Fazakerley; Benjamin L. Parker; Ghazal Sultani; James Lee; Jean-Philippe Stephan; Eric Torres; Kenneth Jung; Coenraad Kuijl; David E. James; Jagath R. Junutula; Jacqueline Stöckli
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Lack of Widespread BBB Disruption in Alzheimer's Disease Models: Focus on Therapeutic Antibodies
Neuron, ISSN: 10974199 08966273
Nga Bien-Ly; C. Andrew Boswell; Surinc Er Jeet; Thomas G. Beach; Kwame Hoyte; Wilman Luk; Vera Shihadeh; Sheila Ulufatu; Oded Foreman; Yanmei Lu; Jason Devoss; Marcel P Van Der Brug; Ryan J. Watts
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Absolute Quantitation of Intact Recombinant Antibody Product Variants Using Mass Spectrometry
Analytical Chemistry, ISSN: 15206882 00032700
Frank D. Macchi; Feng Yang; Charlene Li; Chenchen Wang; Anh Nguyen Dang; Joseph C. Marhoul; Hui-Min Zhang; Timothy Tully; Hongbin Liu; X. Christopher Yu; David A. Michels
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Randomized phase II trial comparing obinutuzumab (GA101) with rituximab in patients with relapsed CD20+ indolent B-Cell non-hodgkin lymphoma: Final analysis of the GAUSS study
Journal of Clinical Oncology, ISSN: 15277755 0732183X
Laurie H. Sehn; Andre Goy; Fritz C. Offner; Giovanni Martinelli; Dolores Caballero; Ole Gadeberg; Tara Baetz; Zelenetz; Gianluca Gaidano; Luis E. Fayad; Rena Buckstein; Jonathan W. Friedberg; Michael Crump; Branimir Jaksic; Pier Luigi Zinzani; Swaminathan Padmanabhan Iyer; Deniz Sahin; Akiko Chai; Guenter Fingerle-Rowson; Oliver W. Press
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PTEN loss in circulating tumour cells correlates with PTEN loss in fresh tumour tissue from castration-resistant prostate cancer patients
British Journal of Cancer, ISSN: 15321827 00070920
Elizabeth A. Punnoose; Roberta Ferraldeschi; Edith Szafer-Glusman; Eric K Tucker; Sankar Mohan; Penelope Flohr; Ruth Riisnaes; Susana Miranda; Ines Figueiredo; Daniel Nava Rodrigues; Aurelius Omlin; Carmel Pezaro; Jin Zhu; Lukas Amler; Premal Patel; Yibing Yan; Natalee Bales; Shannon L. Werner; Jessica Louw; Ajay Pandita; Dena Marrinucci; Gerhardt Attard; De Bono
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Splenic Dendritic Cells Survey Red Blood Cells for Missing Self-CD47 to Trigger Adaptive Immune Responses
Immunity, ISSN: 10974180 10747613
Tangsheng Yi; Jianhua Li; Hsin Chen; Jiaxi Wu; Jinping An; Ying Xu; Yongmei Hu; Clifford Lowell; Jason G. Cyster
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Palladium-Catalyzed Ring Expansion of Spirocyclopropanes to Form Caprolactams and Azepanes
Journal of Organic Chemistry, ISSN: 15206904 00223263
Olivier René; Iain A. Stepek; Alberto Gobbi; Benjamin P. Fauber; Simon Gaines
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Role of Cosolute-Protein Interactions in the Dissociation of Monoclonal Antibody Clusters
Journal of Physical Chemistry B, ISSN: 15205207 15206106
Thomas M. Scherer
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Lipids assist the membrane insertion of a BAM-independent outer membrane protein
Scientific Reports, ISSN: 20452322
Gerard H. M. Huysmans; Ingrid Guilvout; Mohamed Chami; Nicholas N. Nickerson; Anthony P. Pugsley
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Notch signal strength controls cell fate in the haemogenic endothelium
Nature Communications, ISSN: 20411723
Leonor Gama-Norton; Eva Ferrando; Cristina Ruiz-Herguido; Zenhy Liu; Jordi Guiu; Abul B.M.M.K. Islam; Sung-Uk Lee; Minhong Yan; Cynthia J. Guidos; Nuria López-Bigas; Takahiro Maeda; Lluis Espinosa; Raphael Kopan; Anna Bigas
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Mondo-Mlx Mediates Organismal Sugar Sensing through the Gli-Similar Transcription Factor Sugarbabe
Cell Reports, ISSN: 22111247
Jaakko Mattila; Essi Havula; Erja Suominen; Mari Teesalu; Ida Surakka; Riikka Hynynen; Helena Kilpinen; Juho Väänänen; Iiris Hovatta; Reijo Käkelä; Samuli Ripatti; Thomas Sandmann; Ville Hietakangas
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Safety of onartuzumab in patients with solid tumors: Experience to date from the onartuzumab clinical trial program
PLoS ONE, ISSN: 19326203
Roland Morley; Alison Cardenas; Peter Hawkins; Yasuyo Suzuki; Virginia Paton; See Phan; Mark Merchant; Jessie Hsu; Wei Yu; Qi Xia; Daniel Koralek; Patricia Luhn; Wassim Aldairy
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A subset of human bromodomains recognizes butyryllysine and crotonyllysine histone peptide modifications
Structure, ISSN: 18784186 09692126
E. Megan Flynn; Oscar W Huang; Florence Poy; Mariano Oppikofer; Steve Bellon; Yong Tang; Andrea G Cochran
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A phase 2 study of the BH3 mimetic BCL2 inhibitor navitoclax (ABT-263) with or without rituximab, in previously untreated B-cell chronic lymphocytic leukemia
Leukemia and Lymphoma, ISSN: 10292403 10428194
Thomas J. Kipps; Herbert Eradat; Sebastian Grosicki; John Catalano; Walter Cosolo; Iryna S. Dyagil; Sreeni Yalamanchili; Akiko Chai; Srikumar Sahasranaman; Elizabeth A. Punnoose; Deborah Hurst; Halyna Pylypenko
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Negishi Approach to 1,5-Disubstituted 3-Amino-1H-1,2,4-triazoles
Organic Letters, ISSN: 15237052 15237060
Jeff Shen; Brian Wong; Christine Gu; Haiming Zhang
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Gene expression of INPP5F as an independent prognostic marker in fludarabine-based therapy of chronic lymphocytic leukemia
Blood Cancer Journal, ISSN: 20445385
Palermo; Maisel; Martin Barrett; Helen Smith; Guillemette Duchateau-Nguyen; Tri Quang Nguyen; Ru-Fang Yeh; Annika Dufour; Tadeusz Robak; David Dornan; Martin Weisser
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Scaffold-Hopping and Structure-Based Discovery of Potent, Selective, And Brain Penetrant N-(1H-Pyrazol-3-yl)pyridin-2-amine Inhibitors of Dual Leucine Zipper Kinase (DLK, MAP3K12)
Journal of Medicinal Chemistry, ISSN: 15204804 00222623
Snahel Patel; Seth F. Harris; Paul Gibbons; Gauri Deshmukh; Amy Gustafson; Terry Kellar; Han Lin; Xingrong Liu; Yanzhou Liu; Yichin Liu; Changyou Ma; Kimberly Scearce-Levie; Arundhati Sengupta Ghosh; Young G. Shin; Hilda Solanoy; Jian Wang; Bei Wang; Jianping Yin; Michael Siu; Joe Lewcock
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Unliganded fibroblast growth factor receptor 1 forms density-independent dimers
Journal of Biological Chemistry, ISSN: 1083351X 00219258
Laetitia Comps-Agrar; Diana Ronai Dunshee; Dan L. Eaton; Junichiro Sonoda
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Intravitreal administration of known phototoxicants in the rabbit fails to produce phototoxicity: Implications for phototoxicity testing of intravitreally administered small molecule therapeutics
Cutaneous and Ocular Toxicology, ISSN: 15569535 15569527
Evan A Thackaberry; Cindy A. Farman; Vlad Bantseev; Chris Schuetz; Julia F. Baker; Michael H. Brown; Douglas B. Learn
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The Regulation of Immunological Processes by Peripheral Neurons in Homeostasis and Disease
Trends in Immunology, ISSN: 14714981 14714906
Jose Ordovas-Montanes; Seth Rakoff-Nahoum; Siyi Huang; Lorena Riol-Blanco; Olga Barreiro; Ulrich H. von Andrian
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IgSimulator: A versatile immunosequencing simulator
Bioinformatics, ISSN: 14602059 13674803
Yana Safonova; Alla Lapidus; Jennie R. Lill
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Scientific and Regulatory Policy Committee Points-to-consider Paper∗: Drug-induced Vascular Injury Associated with Nonsmall Molecule Therapeutics in Preclinical Development: Part I. Biotherapeutics
Toxicologic Pathology, ISSN: 15331601 01926233
Kendall S. Frazier; Jeffery A. Engelhardt; Pierluigi Fant; Silvia Guionaud; Scott P. Henry; Michael W. Leach; Calvert Louden; Marshall S. Scicchitano; James L. Weaver; Tanja S. Zabka
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Scientific and Regulatory Policy Committee Points-to-consider Paper∗: Drug-induced Vascular Injury Associated with Nonsmall Molecule Therapeutics in Preclinical Development: Part 2. Antisense Oligonucleotides
Toxicologic Pathology, ISSN: 15331601 01926233
Jeffery A. Engelhardt; Pierluigi Fant; Silvia Guionaud; Scott P. Henry; Michael W. Leach; Calvert Louden; Marshall S. Scicchitano; James L. Weaver; Tanja S. Zabka; Kendall S. Frazier
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Therapeutic antibodies: Discovery, design and deployment
Molecular Immunology, ISSN: 18729142 01615890
Paul A. Ramsland; Andrew T. Hutchinson; Paul J. Carter
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Patients with slowly proliferative early breast cancer have low five-year recurrence rates in a phase III adjuvant trial of capecitabine
Clinical Cancer Research, ISSN: 15573265 10780432
O'Shaughnessy; Koeppen; Yuanyuan Xiao; Lackner; Devchand Paul; Christopher Stokoe; John Pippen; Lea Krekow; Frankie Ann Holmes; Svetislava Vukelja; Deborah Lindquist; Scot Sedlacek; Ragene Rivera; Robert Brooks; Kristi McIntyre; Carrie Brownstein; Silke Hoersch; Blum; Stephen Jones
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Identification of N-sulfonyl-tetrahydroquinolines as RORc inverse agonists
Bioorganic and Medicinal Chemistry Letters, ISSN: 14643405 0960894X
Benjamin P. Fauber; Alberto Gobbi; Pascal P. A. Savy; Brenda Burton; Yuzhong Deng; Christine Everett; Hank La; Adam R. Johnson; Peter Lockey; Maxine Norman; Harvey Wong
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Redesigning a monospecific anti-FGFR3 antibody to add selectivity for FGFR2 and expand antitumor activity
Molecular Cancer Therapeutics, ISSN: 15388514 15357163
Yiyuan Yin; Stevan N. Djakovic; Scot A. Marsters; Janet Y. Tien; Jing Peng; Jarrod Tremayne; Genee Y. Lee; Richard M. Neve; Yan Wu; Mark Merchant; Avi Ashkenazi; Paul J. Carter
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NatHER: Protocol for systematic evaluation of trends in survival among patients with HER2-positive advanced breast cancer
Systematic Reviews, ISSN: 20464053
Korner; Anne Morris; I. Elaine Allen; Sara A. Hurvitz; Beattie; Bindu Kalesan
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Alternative molecular formats and therapeutic applications for bispecific antibodies
Molecular Immunology, ISSN: 18729142 01615890
Christoph Spiess; Qianting Zhai; Paul J. Carter
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Investigation of Fragment Antibody Stability and Its Release Mechanism from Poly(Lactide-co-Glycolide)-Triacetin Depots for Sustained-Release Applications
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Debby P. Chang; Vivek Kumar Garripelli; Jennifer C. Rea; Robert F. Kelley; Karthikan Rajagopal
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Final overall survival and safety analysis of OCEANS, a phase 3 trial of chemotherapy with or without bevacizumab in patients with platinum-sensitive recurrent ovarian cancer
Gynecologic Oncology, ISSN: 10956859 00908258
Carol Aghajanian; Barbara Goff; Lawrence R. Nycum; Yan Wang; Amreen Husain; Stephanie V. Blank
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Evaluation of fluorophotometry to assess the vitreal pharmacokinetics of protein therapeutics
Investigative Ophthalmology and Visual Science, ISSN: 15525783 01460404
Leslie Dickmann; Victor Yip; Cuiwen Li; Juan Abundes; Mauricio Maia; Cynthia Young; Shannon Stainton; Hass; Sean B. Joseph; Saileta Prabhu; C. Andrew Boswell
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Comparison of physiologic and pharmacologic parameters in Asian and mauritius cynomolgus macaques
Regulatory Toxicology and Pharmacology, ISSN: 10960295 02732300
John C. Kozlosky; Jagannatha Mysore; Shawn P. Clark; Holly N. Burr; Jinze Li; Nelly Aranibar; Ragini Vuppugalla; Ronald C. West; Raja S. Mangipudy; Michael J. Graziano
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Membrane display and functional analysis of juxtacrine ligand-receptor signaling
BioTechniques, ISSN: 19409818 07366205
Pradeep Nair; Hai Ngu; Eric Torres; Scot A. Marsters; David Lawrence; Jean-Philippe Stephan; László Kömüves; Avi Ashkenazi
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Drug-induced Skin Lesions in Cynomolgus Macaques Treated with Metabotropic Glutamate Receptor 5 (mGluR5) Negative Allosteric Modulators
Toxicologic Pathology, ISSN: 15331601 01926233
Gopinath S. Palanisamy; John M. Marcek; Gregg D. Cappon; Jessica Whritenour; Christopher L. Shaffer; Joseph T. Brady; Christopher Houle
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MTORC2 balances AKT activation and eIF2α serine 51 phosphorylation to promote survival under stress
Molecular Cancer Research, ISSN: 15573125 15417786
Clara Tenkerian; Jothilatha Krishnamoorthy; Zineb Mounir; Urszula Kazimierczak; Arkady Khoutorsky; Kirk A. Staschke; Arnold S. Kristof; Shuo Wang; Maria Hatzoglou; Antonis E. Koromilas
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Population Pharmacokinetics and Pharmacodynamics of Lampalizumab Administered Intravitreally to Patients with Geographic Atrophy
CPT: Pharmacometrics and Systems Pharmacology, ISSN: 21638306
Kha Le; Leonid Gibiansky; Menno Van Lookeren Campagne; Jeremy Good; Teresa Davancaze; Kelly M. Loyet; Alyssa M. Morimoto; Erich C. Strauss; Jin Y. Jin
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Asthma exacerbations and lung function in patients with severe or difficult-to-treat asthma
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
William J. Calhoun; Tmirah Haselkorn; Dave P. Miller; Theodore A. Omachi
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Phase II Randomized Study of Ixabepilone Versus Observation in Patients with Significant Residual Disease after Neoadjuvant Systemic Therapy for HER2-Negative Breast Cancer
Clinical Breast Cancer, ISSN: 19380666 15268209
Ana M. Gonzalez-Angulo; Xiudong Lei; Richardo H. Alvarez; Marjorie Green; James L. Murray; Vicente Valero; Kimberly B. Koenig; Nuhad K. Ibrahim; Jennifer K. Litton; Lakshmy Nair; Savitri Krishnamurthy; Hortobagyi; Funda Meric-Bernstam
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Pathology consultation on gene mutations in acute myeloid leukemia
American Journal of Clinical Pathology, ISSN: 19437722 00029173
James Ziai; Alexa J. Siddon
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Metabolic response of prostate cancer to nicotinamide phophoribosyltransferase inhibition in a hyperpolarized MR/PET compatible bioreactor
Prostate, ISSN: 10970045 02704137
Kayvan R. Keshari; David M. Wilson; Mark Van Criekinge; Renuka Sriram; Bertram L. Koelsch; Zhen J. Wang; Henry F. Vanbrocklin; Donna M. Peehl; Thomas O'Brien; Deepak Sampath; Richard A. D. Carano; John Kurhanewicz
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The airway microbiome in patients with severe asthma: Associations with disease features and severity
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Yvonne J. Huang; Snehal Nariya; Harris; Susan V. Lynch; David F. Choy; Joseph R. Arron; Homer Boushey
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