Scientists / Publications

Publications

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DISPLAYING 7801 - 7850 OF 15487 RESULTS

Engineering and structural characterization of a linear polyubiquitin-specific antibody
Journal of Molecular Biology, ISSN: 10898638 00222836
Marissa L. Matsumoto; Ken Dong; Christine Yu; Lilian Phu; Xinxin Gao; Rami N. Hannoush; Sarah G. Hymowitz; Donald S. Kirkpatrick; Vishva M. Dixit; Robert F. Kelley
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Evolutionarily conserved paired immunoglobulin-like receptor α (PILRα) domain mediates its interaction with diverse sialylated ligands
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Yonglian Sun; Kate Senger; Tomasz K. Baginski; Anita Mazloom; Yvonne Chinn; Homer Pantua; Kajal Hamidzadeh; Sree R. Ramani; Luis; Irene Tom; Andrew Sebrell; Gabriel Quinones; Ma; Kiran Mukhyala; Tao Sai; Jiabing Ding; Benjamin Haley; Hooman Shadnia; Sharookh B. Kapadia; Lino C. Gonzalez Jr.; Hass; Ali A. Zarrin
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Active PI3K pathway causes an invasive phenotype which can be reversed or promoted by blocking the pathway at divergent nodes
PLoS ONE, ISSN: 19326203
Jeffery J. Wallin; Zhengyu Guan; Kyle A. Edgar; Wei Zhou; Ross Francis; Anthony C. Torres; Matthias Peter; Jeffrey Eastham-Anderson; Sabrina Arena; Alberto Bardelli; Sue Griffin; John E. Goodall; Kyla M. Grimshaw; Klaus P. Hoeflich; Christopher Torrance; Marcia Belvin; Lori S. Friedman
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N-Cadherin prodomain processing regulates synaptogenesis
Journal of Neuroscience, ISSN: 02706474 15292401
Analía Reinés; Louis-Philippe Bernier; Robyn McAdam; Wiam Belkaid; Shan; Alexander W. Koch; Philippe Séguéla; David R. Colman; Ajit S. Dhaunchak
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Quantitative evaluation of fucose reducing effects in a humanized antibody on Fcγ receptor binding and antibody-dependent cell-mediated cytotoxicity activities
mAbs, ISSN: 19420862 19420870
Shan Chung; Quarmby; Xiaoying Gao; Yong Ying; Yuwen L. Lin; Chae Reed; Chris Fong; Wendy Lau; Zhihua Julia Qiu; Amy Shen; Vanderlaan; An Song
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Clinical pharmacology of trastuzumab emtansine (T-DM1): An antibody-drug conjugate in development for the treatment of HER2-positive cancer
Cancer Chemotherapy and Pharmacology, ISSN: 03445704 14320843
Sandhya Girish; Manish Gupta; Wang; Dan Lu; Ian E. Krop; Charles L. Vogel; Howard A. Burris; Patricia M. LoRusso; Joo-Hee Yi; Ola M. Saad; Barbara Tong; Yu-Waye Chu; Scott N. Holden; Amita Joshi
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Structure of human ADAM-8 catalytic domain complexed with batimastat
Acta Crystallographica Section F: Structural Biology and Crystallization Communications, ISSN: 17443091
Troii Hall; Huey-Sheng Shieh; Jacqueline E. Day; Nicole Caspers; Jill E. Chrencik; Jennifer M. Williams; Lyle E. Pegg; Adele M. Pauley; Andrea F. Moon; Joseph M. Krahn; David H. Fischer; James R. Kiefer; Alfredo G. Tomasselli; Marc D. Zack
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Inhibition of natural antisense transcripts in vivo results in gene-specific transcriptional upregulation
Nature Biotechnology, ISSN: 10870156 15461696
Farzaneh Modarresi; Mohammad Ali Faghihi; Miguel A Lopez-Toledano; Roya Pedram Fatemi; Marco Magistri; Shaun P Brothers; Marcel P Van Der Brug; Claes Wahlestedt
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Use of the cassette-dosing approach to assess brain penetration in drug discovery
Drug Metabolism and Disposition, ISSN: 00909556 1521009X
Xingrong Liu; Xiao Ding; Gauri Deshmukh; Bianca M. Liederer; Cornelis E. Hop
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Decision Making for a Companion Diagnostic in an Oncology Clinical Development Program
Drug Information Journal, ISSN: 00928615
Lee D. Kaiser; Claus Becker; Sharad Kukreti; Bernard M. Fine
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Tumor angiogenesis mediated by myeloid cells is negatively regulated by CEACAM1
Cancer Research, ISSN: 00085472 15387445
Rongze Lu; Maciej Kujawski; Hao Pan; Shively
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Morphological defects in a novel Rdh10 mutant that has reduced retinoic acid biosynthesis and signaling
Genesis, ISSN: 1526954X 1526968X
Amir M. Ashique; Scott R. May; Maureen A. Kane; Alexandra E. Folias; Khanhky Phamluong; Youngshik Choe; Joseph L. Napoli; Andrew S. Peterson
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ISCOMATRIX vaccines mediate CD8 T-cell cross-priming by a MyD88-dependent signaling pathway
Immunology and Cell Biology, ISSN: 08189641 14401711
Nicholas S. Wilson; Becky Yang; Adriana Baz Morelli; Sandra Koernig; Annie Yang; Stefanie Loeser; Denise Airey; Larissa Provan; Hass; Hal Braley; Suzana Couto; Debbie Drane; Jeff Boyle; Gabrielle T Belz; Avi Ashkenazi; Eugene Maraskovsky
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Wnt signaling in cancer
Cold Spring Harbor Perspectives in Biology, ISSN: 19430264
Paul G. Polakis
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Ubiquilins in the crosstalk among proteolytic pathways
Biological Chemistry, ISSN: 14316730 14374315
Dong Yun Lee; Eric J. Brown
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Feeding lactate for CHO cell culture processes: Impact on culture metabolism and performance
Biotechnology and Bioengineering, ISSN: 00063592 10970290
Jincai Li; Chun Loong Wong; Natarajan Vijayasankaran; Terry Hudson; Ashraf Amanullah
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Clinical implications of pathophysiological and demographic covariates on the population pharmacokinetics of trastuzumab emtansine, a HER2-targeted antibody-drug conjugate, in patients with HER2-positive metastatic breast cancer
Journal of Clinical Pharmacology, ISSN: 00912700 15524604
Manish Gupta; Patricia M. LoRusso; Wang; Joo-Hee Yi; Howard A. Burris; Muralidhar Beeram; Shanu Modi; Yu-Waye Chu; Samuel Agresta; Barbara Klencke; Amita Joshi; Sandhya Girish
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Mini-scale bioprocessing systems for highly parallel animal cell cultures
Biotechnology Progress, ISSN: 87567938 15206033
Beum Jun Kim; Jinpian Diao; Michael L. Shuler
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The pharmacokinetics of lersivirine (UK-453,061) and HIV-1 protease inhibitor coadministration in healthy subjects
Journal of Acquired Immune Deficiency Syndromes, ISSN: 15254135 10779450
Manoli Vourvahis; Grant Langdon; Gary Layton; Robert R. LaBadie; Heng Wee Choo; Marie-Noella Ndongo; John Davis
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Trends in the incidence of noncardiogenic acute respiratory failure: The role of race
Critical Care Medicine, ISSN: 00903493 15300293
Colin R. Cooke; Sara E. Erickson; Mark D. Eisner; Greg S. Martin
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Preclinical stereoselective disposition and toxicokinetics of two novel MET inhibitors
Xenobiotica, ISSN: 00498254 13665928
Bianca M. Liederer; Xingrong Liu; Leonid M. Berezhkovskiy; Cain; Xiao Ding; John J. Gaudino; Robert Kaus; Emile G. Plise; Daniel P. Sutherlin; Eric Harstad
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Maximizing tumour exposure to anti-neuropilin-1 antibody requires saturation of non-tumour tissue antigenic sinks in mice
British Journal of Pharmacology, ISSN: 00071188 14765381
Daniela Bumbaca; Hong Xiang; C. Andrew Boswell; Ruediger E. Port; Shannon Stainton; Eduardo E. Mundo; Sheila Ulufatu; Anil Bagri; Frank-Peter Theil; Fielder; Leslie A. Khawli; Shen
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Introduction for the special issue on glycosylation and immunity
Seminars in Immunopathology, ISSN: 18632297 18632300
John Lowe
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Gastrointestinal perforation associated with bevacizumab use in metastatic colorectal cancer: Results from a large treatment observational cohort study
European Journal of Cancer, ISSN: 09598049 18790852
Fairooz F. Kabbinavar; Patrick J. Flynn; Kozloff; Ashby; Amy Sing; Charles E. Barr; Grothey
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Preclinical disposition of GDC-0973 and prospective and retrospective analysis of human dose and efficacy predictions
Drug Metabolism and Disposition, ISSN: 00909556 1521009X
Edna F. Choo; Marcia Belvin; Jason Boggs; Yuzhong Deng; Klaus P. Hoeflich; Justin Ly; Mark Merchant; Christine Orr; Emile G. Plise; Kirk D. Robarge; Jean-Francois Martini; Robert Kassees; Ron Aoyama; Atulkumar Ramaiya; Stuart H. Johnston
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Transcriptional analysis of pluripotency reveals the hippo pathway as a barrier to reprogramming
Human Molecular Genetics, ISSN: 09646906 14602083
Han Qin; Kathryn Blaschke; Grace Wei; Yuki Ohi; Laure Blouin; Zhongxia Qi; Jingwei Yu; Ru-Fang Yeh; Matthias Hebrok; Miguel Ramalho-santos
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High-throughput methods for miniaturization and automation of monoclonal antibody purification processes
Biotechnology Progress, ISSN: 87567938 15206033
Katrin Treier; Sigrid Hansen; Carolin Richter; Patrick Diederich; Jürgen Hubbuch; Philip M. Lester
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Proteus: A web-based, context-specific modelling tool for molecular networks
Bioinformatics, ISSN: 13674803 14602059
Florian Gnad; Javier Estrada; Jeremy Gunawardena
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Online FDA Resources Versus Data on File: Minimizing Data on File in Standard Medical Response Letters
Drug Information Journal, ISSN: 00928615
Nancy Hwang; Graham; Marbel Catolico
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Standardization of single use components' extractable studies for industry
Pharmaceutical Engineering, ISSN: 02738139
Ekta Mahajan; Trishna Ray-Chaudhuri; James Dean Vogel
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From the editor
BioProcess International, ISSN: 15426319
Siddharth Advant; Hazel Aranha; Milton J. Axley; R. Lee Buckler; Michel Chartrain; Nancy Chew; Laurel Donahue-Hjelle; John Dougherty; Don R. Durham; Jim Faulkner; Pete Gagnon; Hélène Gazzano-Santoro; Rick Hancock; Timothy K. Hayes; Kenneth Hughes; Susan Dana Jones; Alex D. Kanarek; Dennis M. Kraichely; Vadim Klyushnichenko; Fred Mann; Adriana E. Manzi; Otto-Wilhelm Merten; Thomas J. Pritchett; T. Shantha Raju; Nadine Ritter; Sally Seaver; Robert P. Shaw; Abhinav Shukla; Michiel Ultee; Scott M. Wheelwright; William G. Whitford; Shuichi Yamamoto; Jianguo Yang; Xiaoming Yang
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Best practice in the conduct of key nonclinical cardiovascular assessments in drug development: Current recommendations from the Safety Pharmacology Society
Journal of Pharmacological and Toxicological Methods, ISSN: 10568719 1873488X
Leishman; Beck; Noel Dybdal; Gallacher; Guth; Holbrook; Brian Roche; Wallis
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Translation levels control multi-spanning membrane protein expression
PLoS ONE, ISSN: 19326203
Hok Seon Kim; James A. Ernst; Cecilia Brown; Jenny Bostrom; Fuh; Chingwei V. Lee; Arthur Huang; Richard L. Vandlen; Yansura
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Cilia - the prodigal organelle
Cilia, ISSN: 20462530
Phil Beales; Peter K Jackson
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Structural and functional characterization of monomeric EphrinA1 binding site to EphA2 receptor
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Carla M. Lema Tome; Enzo Palma; Sara Ferluga; W. Todd Lowther; Roy Hantgan; Jill Wykosky; Waldemar Debinski
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FGF19 and cancer
Advances in Experimental Medicine and Biology, ISSN: 00652598
Benjamin C. Lin; Luc Desnoyers
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Formal synthesis of (+)-crocacin C
Tetrahedron Letters, ISSN: 00404039 18733581
Adele E. Pasqua; Frank D. Ferrari; James J. Crawford; Rodolfo Marquez
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Genetic and Epigenetic Determinants of Neurogenesis and Myogenesis
Developmental Cell, ISSN: 15345807 18781551
Abraham P. Fong; Zizhen Yao; Jun Wen Zhong; Yi Cao; Walter L. Ruzzo; Robert Gentleman; Stephen J. Tapscott
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DNA methylation profiling defines clinically relevant biological subsets of non-small cell lung cancer
Clinical Cancer Research, ISSN: 10780432 15573265
Kimberly Walter; Thomas Holcomb; Thomas Januario; Pan Du; Marie Evangelista; Nithya Kartha; Leonardo Iniguez; Robert Soriano; Huw; Howard M. Stern; Zora Modrusan; Somasekar Seshagiri; Garret M. Hampton; Lukas Amler; Richard Bourgon; Robert Yauch; David S. Shames
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Oncogenic KRAS-induced interleukin-8 overexpression promotes cell growth and migration and contributes to aggressive phenotypes of non-small cell lung cancer
International Journal of Cancer, ISSN: 00207136 10970215
Sunaga; Imai; Shimizu; David S. Shames; Seiichi Kakegawa; Girard; Sato; Kaira; Ishizuka; Adi Gazdar; Minna; Mori
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CDK8 maintains tumor dedifferentiation and embryonic stem cell pluripotency
Cancer Research, ISSN: 00085472 15387445
Adam S. Adler; Mark L. McCleland; Tom Truong; Shari Lau; Zora Modrusan; Tim M. Soukup; Merone Roose-Girma; Elizabeth M. Blackwood; Ron Firestein
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Evaluation of circulating tumor cells and circulating tumor DNA in non-small cell lung cancer: Association with clinical endpoints in a phase II clinical trial of pertuzumab and erlotinib
Clinical Cancer Research, ISSN: 10780432 15573265
Elizabeth A. Punnoose; Siminder Atwal; Weiqun Liu; Rajiv Raja; Bernard M. Fine; Brett Hughes; Rodney Hicks; Garret M. Hampton; Lukas Amler; Andrea Pirzkall; Lackner
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Rapamycin with antiretroviral therapy in AIDS-associated kaposi sarcoma: An AIDS malignancy consortium study
Journal of Acquired Immune Deficiency Syndromes, ISSN: 15254135 10779450
Susan E. Krown; Debasmita Roy; Jeannette Y. Lee; Bruce J. Dezube; Erin G. Reid; Raman Venkataramanan; Kelong Han; Ethel Cesarman; Dirk P. Dittmer
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Application of genetic algorithms and response surface analysis for the optimization of batch chromatographic systems
Biochemical Engineering Journal, ISSN: 1369703X 1873295X
Katrin Treier; Philip M. Lester; Jürgen Hubbuch
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Inhibiting alternative pathway complement activation by targeting the factor D exosite
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Kenneth J. Katschke Jr.; Ping Wu; Rajkumar Ganesan; Robert F. Kelley; Mary Mathieu; Hass; Jeremy Murray; Daniel Kirchhofer; Wiesmann; Menno Van Lookeren Campagne
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Transcriptional induction of salt-inducible kinase 1 by transforming growth factor β leads to negative regulation of type I receptor signaling in cooperation with the Smurf2 ubiquitin ligase
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Peter Lönn; Michael Vanlandewijck; Erna Raja; Marcin Kowanetz; Yukihide Watanabe; Katarzyna Kowanetz; Eleftheria Vasilaki; Carl-Henrik Heldin; Aristidis Moustakas
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The authors reply
New England Journal of Medicine, ISSN: 00284793 15334406
Baselga; Benyunes; Sandra M. Swain
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Structural basis for the dual recognition of helical cytokines IL-34 and CSF-1 by CSF-1R
Structure, ISSN: 09692126 18784186
Xiaolei Ma; Wei Yu Lin; Yongmei Chen; Scott Stawicki; Kiran Mukhyala; Yan Wu; Flavius Martin; J.Fernando Bazan; Melissa A. Starovasnik
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1,4-Induction in aldol reactions of (tertiary α′-alkoxy)methyl ketones: Synthesis of the C 8-C 11 stereotriad of ent-fostriecin
Tetrahedron Letters, ISSN: 00404039 18733581
Nicholas Cowper; Soula Azzi; Kristina Dupont-Gaudet; Jason D. Burch
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Structure of TIGIT immunoreceptor bound to poliovirus receptor reveals a cell-cell adhesion and signaling mechanism that requires cis-trans receptor clustering
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Katharina F. Stengel; Kristin Harden; Xin Yu; Lionel Rouge; Jianping Yin; Laetitia Comps-Agrar; Wiesmann; J.Fernando Bazan; Dan L. Eaton; Jane L. Grogan
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