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Publications

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DISPLAYING 7951 - 8000 OF 15394 RESULTS

Viscosity behavior of high-concentration monoclonal antibody solutions: Correlation with interaction parameter and electroviscous effects
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Sandeep Yadav; Steven J. Shire; Devendra S. Kalonia
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Transforming the untransformable: Application of direct transformation to manipulate genetically Staphylococcus aureus and Staphylococcus epidermidis
mBio, ISSN: 21507511
Ian R. Monk; Ishita M. Shah; Min Xu; Man-Wah Tan; Timothy J. Foster
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Viscosity behavior of high-concentration protein mixtures
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
William J. Galush; Lan N. Le; Jamie M. R. Moore
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Influenza a virus infection of human primary dendritic cells impairs their ability to cross-present antigen to CD8 T cells
PLoS Pathogens, ISSN: 15537374 15537366
Anna Smed-Sörensen; Cecile Chalouni; Bithi Chatterjee; Lillian Cohn; Peter Blattmann; Norihiro Nakamura; Lélia Delamarre; Ira Mellman
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Pooled analysis of cardiac safety in patients with cancer treated with pertuzumab
Annals of Oncology, ISSN: 15698041 09237534
Lenihan; Suter; Melissa Brammer; Neate; Graham Ross; Baselga
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Escherichia coli Serotype O55:H7 Diversity Supports Parallel Acquisition of Bacteriophage at Shiga Toxin Phage Insertion Sites during evolution of the O157:H7 lineage
Journal of Bacteriology, ISSN: 10985530 00219193
Jennifer L. Kyle; Craig A. Cummings; Craig T. Parker; Beatriz Quiñones; Paolo Vatta; Elizabeth Newton; Steven Huynh; Michelle Swimley; Lovorka Degoricija; Melissa Barker; Samar Fontanoz; Kimberly Nguyen; Ronak Patel; Rixun Fang; Robert Tebbs; Olga Petrauskene; Manohar Furtado; Robert E. Mandrell
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Effect of IL28B genotype on early viral kinetics during interferon-free treatment of patients with chronic hepatitis C
Gastroenterology, ISSN: 15280012 00165085
Tom W. Chu; Rohit Kulkarni; Edward J. Gane; Stuart K. Roberts; Catherine Stedman; Peter Angus; Brett Ritchie; Xiao-Yu Lu; David Ipe; Uri Lopatin; Søren Germer; Victor A. Iglesias; Robert Elston; Patrick F. Smith; Nancy Shulman
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Phase transformation in thiamine hydrochloride tablets: Influence on tablet microstructure, physical properties, and performance
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Paroma Chakravarty; Raj Suryanarayanan; Ramprakash Govindarajan
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Glucocorticoid receptor β and histone deacetylase 1 and 2 expression in the airways of severe asthma
Thorax, ISSN: 14683296 00406376
Claire A. Butler; Stephen McQuaid; Cliff C. Taggart; Sinead Weldon; Richard Carter; Grzegorz Skibinski; Timothy J. Warke; David F. Choy; Lorcan P. McGarvey; Peter Bradding; Joseph R. Arron; Liam G. Heaney
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Synapses and Alzheimer's disease
Cold Spring Harbor Perspectives in Biology, ISSN: 19430264
Morgan Sheng; Bernardo L Sabatini; Thomas C. Südhof
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Preclinical molecular imaging of the translocator protein (TSPO) in a metastases model based on breast cancer xenografts propagated in the murine brain
Current Molecular Medicine, ISSN: 18755666 15665240
Shelby K. Wyatt; H. Charles Manning; Mingfeng Bai; Moneeb Ehtesham; Khubaib Y. Mapara; Reid C. Thompson; Darryl J. Bornhop
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Applying Nonexperimental Study Approach to Analyze Historical Batch Data
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Yong Cui; Xiling Song; King Chuang; Minli Xie
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Contribution of a single host genetic locus to mouse adenovirus type 1 infection and encephalitis
mBio, ISSN: 21507511
Tien-Huei Hsu; Irene W. Althaus; Oded Foreman; Katherine R. Spindlera
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Phase II study of eribulin mesylate (E7389) in patients with metastatic castration-resistant prostate cancer stratified by prior taxane therapy
Annals of Oncology, ISSN: 15698041 09237534
De Bono; Molife; Guru Sonpavde; Pablo Maroto; Calvo; Cartwright; Loesch; Feit; Asha Das; Zang; Wanders; Agoulnik; Petrylak
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On the accuracy of determination of unbound drug fraction in tissue using diluted tissue homogenate
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy
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Symptom burden & quality of life among patients receiving second-line treatment of metastatic colorectal cancer
BMC Research Notes, ISSN: 17560500
Mark S. Walker; Elaine B. Yu; Jiandong Kerr; Yeun Mi Yim; Edward J. Stepanski; Lee S. Schwartzberg
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FDG-PET is a good biomarker of both early response and acquired resistance in BRAFV600 mutant melanomas treated with vemurafenib and the MEK inhibitor GDC-0973
EJNMMI Research, ISSN: 2191219X
Andreas R. Baudy; Taner Dogan; Judith E. Flores; Klaus P. Hoeflich; Fei Su; Nicholas Van Bruggen; Simon P. Williams
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Quantitation of glucose uptake in tumors by dynamic FDG-PET has less glucose bias and lower variability when adjusted for partial saturation of glucose transport
EJNMMI Research, ISSN: 2191219X
Simon P. Williams; Judith E. Flores; Ruediger E. Port; Thomas Bengtsson
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The power of FDG PET to detect treatment effects is increased by glucose correction using a Michaelis constant
EJNMMI Research, ISSN: 2191219X
Simon P. Williams; Judith E. Flores; Andreas R. Baudy; Ruediger E. Port; Thomas Bengtsson
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Anti-VEGF antibody therapy does not promote metastasis in genetically engineered mouse tumour models
Journal of Pathology, ISSN: 10969896 00223417
Mallika Singh; Suzana Couto; William F. Forrest; Anthony Lima; Jason H. Cheng; Rafael Molina; Jason E. Long; Patricia Hamilton; Angela McNutt; Ian Kasman; Michelle Nannini; Hani Bou-Reslan; Tim C. Cao; Calvin Ho; Kai H. Barck; Richard A. D. Carano; Oded Foreman; Jeffrey Eastham-Anderson; Adrian M. Jubb; Napoleone Ferrara; Leisa Johnson
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Mechanisms of acquired resistance to targeted cancer therapies
Future Oncology, ISSN: 17448301 14796694
Lackner; Wilson; Jeffrey Settleman
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Key findings and clinical implications from the Epidemiology and Natural History of Asthma: Outcomes and Treatment Regimens (TENOR) study
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Bradley E. Chipps; Robert S. Zeiger; Larry Borish; Sally E. Wenzel; Ashley Yegin; Mary Lou Hayden; Dave P. Miller; Eugene R. Bleecker; F. Estelle R. Simons; Stanley J. Szefler; Weiss; Tmirah Haselkorn
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The potential clinical relevance of visible particles in parenteral drugs
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Lucette Doessegger; Hanns-Christian Mahler; Piotr Szczesny; Helmut Rockstroh; Georg Kallmeyer; Anja Langenkamp; Joerg Herrmann; Joseph Famulare
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An 'all-inclusive' 96-well cytochrome P450 induction method: Measuring enzyme: Activity, mrna levels, protein levels, and cytotoxicity from one well using: Cryopreserved human hepatocytes
Journal of Pharmacological and Toxicological Methods, ISSN: 1873488X 10568719
Jason S Halladay; Susan C. Wong; S. Cyrus Khojasteh; Susan Grepper
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Rheumatoid arthritis and the incidence of influenza and influenza-related complications: A retrospective cohort study
BMC Musculoskeletal Disorders, ISSN: 14712474
William A. Blumentals; Anna Arreglado; Pavel Napalkov; Stephen Toovey
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Periostin is a systemic biomarker of eosinophilic airway inflammation in asthmatic patients
Journal of Allergy and Clinical Immunology, ISSN: 10976825 00916749
Guiquan Jia; Erickson; David F. Choy; Mosesova; Lawren C. Wu; Owen D. Solberg; Aarti Shikotra; Richard Carter; Séverine Audusseau; Qutayba Hamid; Peter Bradding; John V. Fahy; Prescott G. Woodruff; Harris; Joseph R. Arron
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Targeting FGFR4 inhibits hepatocellular carcinoma in preclinical mouse models.
PLoS ONE, ISSN: 19326203
French; Benjamin C. Lin; Manping Wang; Adams; Theresa Shek; Kathy Hötzel; Brad Bolon; Ron Ferrando; Craig Blackmore; Kurt A. Schroeder; Luis A Rodriguez; Maria Hristopoulos; Rayna Venook; Avi Ashkenazi; Luc Desnoyers
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Effects of commercial air travel on patients with pulmonary hypertension
Chest, ISSN: 19313543 00123692
Nareg Roubinian; C. Gregory Elliott; Christopher F. Barnett; Paul D. Blanc; Joan Chen; Teresa De Marco; Hubert Chen
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Determination of hepatic clearance with the account of drug-protein binding kinetics
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy
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A phase i study of erlotinib and hydroxychloroquine in advanced non-small-cell lung cancer
Journal of Thoracic Oncology, ISSN: 15561380 15560864
Sarah B. Goldberg; Jeffrey G. Supko; Joel W. Neal; Alona Muzikansky; Subba Digumarthy; Panos Fidias; Jennifer S. Temel; Rebecca S. Heist; Alice T. Shaw; Patricia O. McCarthy; Thomas J. Lynch; Sreenath Sharma; Jeffrey Settleman; Lecia V. Sequist
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Compatibility, physical stability, and characterization of an IgG4 monoclonal antibody after dilution into different intravenous administration bags
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Ozan S. Kumru; Jun Liu; Junyan A. Ji; Wilson Cheng; Y. John Wang; Tingting Wang; Sangeeta B. Joshi; C. Russell Middaugh; David B. Volkin
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Comparative assessment of In Vitro-In Vivo extrapolation methods used for predicting hepatic metabolic clearance of drugs
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Patrick Poulin; Cornelis E. Hop; Quynh Ho; Jason S Halladay; Sami Haddad; Jane R. Kenny
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Bevacizumab maintenance in patients with advanced non-small-cell lung cancer, clinical patterns, and outcomes in the eastern cooperative oncology group 4599 study: Results of an exploratory analysis
Journal of Thoracic Oncology, ISSN: 15561380 15560864
Ariel Lopez-Chavez; Todd Young; Sophie Fages; Larry Leon; Joan H. Schiller; Afshin Dowlati; Julie Brahmer; David H. Johnson; Alan Sandler
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Erratum:Ungersma et al., vessel imaging with viable tumor analysis for quantification of tumor angiogenesis.(Magnetic Resonance in Medicine 2010 63 (1637-1647))
Magnetic Resonance in Medicine, ISSN: 15222594 07403194
Sharon E. Ungersma; Glenn Pacheco; Calvin Ho; Sharon Fong Yee; Ross; Nicholas Van Bruggen; Franklin V. Peale Jr.; Ross; Richard A. D. Carano
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Conceptual underestimation of the total body clearance by the sum of clearances of individual organs in physiologically based pharmacokinetics
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Leonid M. Berezhkovskiy
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Variable selection in multivariate modeling of drug product formula and manufacturing process
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Yong Cui; Xiling Song; King Chuang; Venkatramani; Sueanne Lee; Gregory Gallegos; Thirunellai Venkateshwaran; Minli Xie
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Investigating high-concentration monoclonal antibody powder suspension in nonaqueous suspension vehicles for subcutaneous injection
Journal of Pharmaceutical Sciences, ISSN: 15206017 00223549
Mayumi Bowen; Nick Armstrong; Maa
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Phase i clinical, pharmacokinetic, and pharmacodynamic study of KOS-862 (Epothilone D) in patients with advanced solid tumors and lymphoma
Investigational New Drugs, ISSN: 15730646 01676997
Jason Konner; Rachel N. Grisham; Jae Park; Owen A. O'Connor; Gillian Cropp; Robert Johnson; Alison L. Hannah; Martee L. Hensley; Paul Sabbatini; Svetlana Miranov; Samuel Danishefsky; David Hyman; David R. Spriggs; Jakob Dupont; Carol Aghajanian
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Evaluation of time-dependent cytochrome P450 inhibition in a high-throughput, automated assay: Introducing a novel area under the curve shift approach
Drug Metabolism Letters, ISSN: 18723128
Sophie Mukadam; Suzanne Tay; Daniel Tran; Leslie Wang; Erlie Marie Delarosa; S. Cyrus Khojasteh; Jason S Halladay; Jane R. Kenny
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A very short history of structure-based design: How did we get here and where do we need to go?
Journal of Computer-Aided Molecular Design, ISSN: 15734951 0920654X
Jeff Blaney
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SpeCond: A method to detect condition-specific gene expression
Genome Biology, ISSN: 14747596 1474760X
Florence M.G. Cavalli; Richard Bourgon; Juan M. Vaquerizas; Nicholas M. Luscombe
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The A-MYSM Power of Deubiquitinases
Immunity, ISSN: 10747613 10974180
Ignacio A. Demarco; Harinder Singh
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The authors reply
New England Journal of Medicine, ISSN: 00284793 15334406
Joseph R. Arron; Jonathan Corren; Matthews
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Cancer immunotherapy comes of age
Nature, ISSN: 14764687 00280836
Ira Mellman; George Coukos; Glenn Dranoff
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Identification of surprisingly diverse type IV Pili, across a broad range of gram-positive bacteria
PLoS ONE, ISSN: 19326203
Saheed Imam; Zhongqiang Chen; David S. Roos; Mechthild Pohlschröder
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TRAF2 and cellular IAPs: A critical link in TNFR family signaling
Advances in Experimental Medicine and Biology, ISSN: 00652598
Domagoj Vucic
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Workshop summary: Novel aspects of the functions of the TRAFs and cIAPs
Advances in Experimental Medicine and Biology, ISSN: 00652598
John Silke; Domagoj Vucic
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Metabolic disease: Amelioration of type 2 diabetes by antibody-mediated activation of fibroblast growth factor receptor 1
Science Translational Medicine, ISSN: 19466242 19466234
Ai-Luen Wu; Ganesh Kolumam; Scott Stawicki; Yongmei Chen; Jun Li; Jose Zavala-Solorio; Khanhky Phamluong; Bo Feng; Li Li; Scot A. Marsters; Lance Kates; Nicholas Van Bruggen; Maya Leabman; Anne Wong; David West; Howard M. Stern; Luis; Hok Seon Kim; Yansura; Andrew S. Peterson; Ellen H. Filvaroff; Yan Wu; Junichiro Sonoda
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Influence of 17β-estradiol on gene expression of paracoccidioides during mycelia-to-yeast transition
PLoS ONE, ISSN: 19326203
Jata Shankar; Thomas D Wu; Karl V. Clemons; Jomar P. Monteiro; Laurence F. Mirels; David A. Stevens
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Amelioration of type 2 diabetes by antibody-mediated activation of fibroblast growth factor receptor 1.
Science Translational Medicine, ISSN: 19466242
Ai-Luen Wu; Ganesh Kolumam; Scott Stawicki; Yongmei Chen; Jun Li; Jose Zavala-Solorio; Khanhky Phamluong; Feng; Li; Scot A. Marsters; Lance Kates; Nicholas Van Bruggen; Maya Leabman; Anne Wong; David A. West; Howard M. Stern; Luis; Hok Seon Kim; Yansura; Andrew S. Peterson; Ellen H. Filvaroff; Yan Wu; Junichiro Sonoda
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