Scientists / Publications

Publications

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DISPLAYING 8401 - 8450 OF 15658 RESULTS

Access to saturated fused pyrimidine derivatives via a flexible N -vinyl tertiary enamide synthesis
Synlett, ISSN: 09365214 14372096
Anthony A. Estrada; Joseph P. Lyssikatos; Frederic St-Jean; Philippe Bergeron
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Phage display of tissue inhibitor of metalloproteinases-2 (TIMP-2): Identification of selective inhibitors of collagenase-1 (metalloproteinase 1 (MMP-1))
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Harinath Bahudhanapati; Yingnan Zhang; Sachdev S. Sidhu; Keith Brew
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Purification Process Design and the Influence of Product and Technology Platforms
Comprehensive Biotechnology, Second Edition,
Chris Dowd; Kelley
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Disposable Bioreactors
Comprehensive Biotechnology, Second Edition,
Oosterhuis; Terry Hudson; D'Avino; Zijlstra; Ashraf Amanullah
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Process Validation
Comprehensive Biotechnology, Second Edition,
David H. Reifsnyder; Nathan McKnight; Kelley
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DLK induces developmental neuronal degeneration via selective regulation of proapoptotic JNK activity
Journal of Cell Biology, ISSN: 00219525 15408140
Arundhati Sengupta Ghosh; Bei Wang; Christine D. Pozniak; Mark Chen; Ryan J. Watts; Joe Lewcock
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The interleukin-17 cytokine family: Critical players in host defence and inflammatory diseases
Immunology, ISSN: 00192805 13652567
Rajita Pappu; Vladimir Ramirez-Carrozzi; Arivazhagan Sambandam
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Conference report: The AAPS national biotechnology conference
Therapeutic Delivery, ISSN: 20415990 20416008
Margaret Kenrick
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Bounds for an estimate of the optimal backward error for linear least squares problems
International Journal of Computer Mathematics, ISSN: 00207160 10290265
Zheng Su
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2011 White paper on recent issues in bioanalysis and regulatory findings from audits and inspections
Bioanalysis, ISSN: 17576180 17576199
Fabio Garofolo; Mario Rocci; Isabelle Dumont; Suzanne Martinez; Steve Lowes; Eric Woolf; Peter Van Amsterdam; Surendra Bansal; Ariadna Cristina Gomes Barra; Ronald Bauer; Brian Booth; Montserrat Carrasco-Triguero; Binodh DeSilva; John Dunn; Keith Gallicano; Dominique Gouty; Stacy Ho; Richard Hucker; Mohammed Jemal; Noriko Katori; Olivier Le Blaye; Jean W. Lee; Wenkui Li; Steve Michael; Corey Nehls; Robert Nicholson; Eric Ormsby; Daniel Tang; Viswanathan; Russell Weiner; Graeme Young
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PPM1H Is a p27 phosphatase implicated in trastuzumab resistance
Cancer Discovery, ISSN: 21598274 21598290
Si Tuen Lee-Hoeflich; Thinh Q. Pham; Dowbenko; Xander Munroe; James Lee; Li Li; Wei Zhou; Matthias Peter; Kanan Pujara; Stinson; Sara M. Chan; Jeffrey Eastham-Anderson; Ajay Pandita; Somasekar Seshagiri; Klaus P. Hoeflich; Gulisa Turashvili; Karen A. Gelmon; Samuel A. Aparicio; David P. Davis; Mark X. Sliwkowski; Howard M. Stern
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The science of project management: Project controls systems integration
Pharmaceutical Engineering, ISSN: 02738139
Frederick Cramer; Susanne Keller; Christopher Law; Thomas Shih; Britton L. Wolf
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A hybrid approach to predicting events in clinical trials with time-to-event outcomes
Contemporary Clinical Trials, ISSN: 15517144 15592030
Liang Fang; Zheng Su
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Randomized, placebo-controlled clinical trial of an aerosolized β2-agonist for treatment of acute lung injury
American Journal of Respiratory and Critical Care Medicine, ISSN: 1073449X 15354970
Michael A. Matthay; Roy G. Brower; Shannon Carson; Ivor S. Douglas; Mark D. Eisner; Duncan Hite; Steven Holets; Richard H. Kallet; Kathleen D. Liu; Neil MacIntyre; Marc Moss; David Schoenfeld; Jay S. Steingrub; B. Taylor Thompson
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Dextran sieving test for characterization of virus filtration membranes
Journal of Membrane Science, ISSN: 03767388 18733123
Meisam Bakhshayeshi; Dharmesh M. Kanani; Amit Mehta; Robert Van Reis; Ralf Kuriyel; Nigel B. Jackson; Andrew Zydney
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Cross talk between ubiquitination and demethylation
Molecular and Cellular Biology, ISSN: 02707306 10985549
Xiaodong Huang; Vishva M. Dixit
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Magnetic resonance imaging in rheumatoid arthritis clinical trials: Emerging patterns based on recent experience
Journal of Rheumatology, ISSN: 0315162X 14992752
Charles G. Peterfy; Peter Countryman; Annarita Gabriele; Tim Shaw; Andrew Anisfeld; Wayne Tsuji; Ewa Olech; Norman B. Gaylis; Philip G. Conaghan; Vibeke Strand; Julie DiCarlo
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Evaluation of homogenization techniques for the preparation of mouse tissue samples to support drug discovery
Bioanalysis, ISSN: 17576180 17576199
Xiaorong Liang; Savita Ubhayakar; Bianca M. Liederer; Brian J. Dean; Ann R. Qin; Sheerin Shahidi-Latham; Yuzhong Deng
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A note on importance resampling for multi-dimensional statistics
Communications in Statistics: Simulation and Computation, ISSN: 03610918 15324141
Zheng Su
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Proteolytic activation of pro-macrophage-stimulating protein by hepsin
Molecular Cancer Research, ISSN: 15417786 15573125
Rajkumar Ganesan; Ganesh Kolumam; S. Jack Lin; Xie; Santell; Thomas D Wu; Lazarus; Amitabha Chaudhuri; Daniel Kirchhofer
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Integrated safety in tocilizumab clinical trials
Arthritis Research and Therapy, ISSN: 14786354 14786362
Michael H. Schiff; Joel M. Kremer; Angelika Jahreis; Emma Vernon; John D. Isaacs; Ronald Van Vollenhoven
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An Audit Strategy for Progression-Free Survival
Biometrics, ISSN: 15410420 0006341X
Lori E. Dodd; Edward L. Korn; Boris Freidlin; Robert Gray; Suman Bhattacharya
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Decision Making for a Companion Diagnostic in an Oncology Clinical Development Program
Drug Information Journal, ISSN: 00928615
Lee D. Kaiser; Claus Becker; Sharad Kukreti; Bernard M. Fine
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Uniting small molecule and biologic drug perspectives: Analytical characterization and regulatory considerations for antibody-drug conjugates
BioProcess International, ISSN: 15426319
Jon Harris; Fred Jacobson; Claudia Jochheim; Godfrey Amphlett; Kathleen Francissen; Lorna McLeod
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Use of confocal scanning laser microscopy to study virus retention during virus filtration
Journal of Membrane Science, ISSN: 03767388 18733123
Meisam Bakhshayeshi; Nigel B. Jackson; Ralf Kuriyel; Amit Mehta; Robert Van Reis; Andrew Zydney
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Pharmacokinetic dose-scheduling study of hedgehog pathway inhibitor vismodegib (GDC-0449) in patients with locally advanced or metastatic solid tumors
Clinical Cancer Research, ISSN: 10780432 15573265
Patricia M. LoRusso; Antonio Jimeno; Grace Dy; Alex Adjei; Jordan Berlin; Lawrence Leichman; Low; Dawn Colburn; Ilsung Chang; Sravanthi Cheeti; Jin Y. Jin; Richard A. Graham
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Stems to gems: Impact of stem cell technology on engineered animal models
Veterinary Pathology, ISSN: 03009858 15442217
Wendy Halpern; Mark McArthur; Elizabeth Galbreath; Elizabeth Uhl; Wayne Buck; Elizabeth Whitley
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A20 edits ubiquitin and autoimmune paradigms
Nature Genetics, ISSN: 10614036 15461718
Flavius Martin; Vishva M. Dixit
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AAPS workshop report: Strategies to address therapeutic protein-drug interactions during clinical development
AAPS Journal, ISSN: 15507416
Sandhya Girish; Steven W Martin; Mark C Peterson; Lei K. Zhang; Hong Zhao; Joseph P. Balthasar; Raymond Evers; Honghui Zhou; Min Zhu; Lewis Klunk; Chao Han; Eva Gil Berglund; Huang; Amita Joshi
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Efficient production of antibodies against a mammalian integral membrane protein by phage display
Protein Engineering, Design and Selection, ISSN: 17410126 17410134
Isidro Hötzel; Vicki Chiang; Jingyu Diao; Homer Pantua; Henry R. Maun; Sharookh B. Kapadia
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Lyp breakdown and autoimmunity
Nature Genetics, ISSN: 10614036 15461718
Timothy W. Behrens
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Asthma in the elderly: Current understanding and future research needs - A report of a National Institute on Aging (NIA) workshop
Journal of Allergy and Clinical Immunology, ISSN: 00916749 10976825
Nicola A. Hanania; Monroe J. King; Sidney S. Braman; Carol Saltoun; Robert A. Wise; Paul Enright; Ann R. Falsey; Sameer K. Mathur; Joe W. Ramsdell; Linda Rogers; David A. Stempel; John Lima; James E. Fish; Sandra R. Wilson; Cynthia Boyd; Kushang V. Patel; Charles G. Irvin; Barbara P. Yawn; Ethan A. Halm; Stephen I. Wasserman; Mark F. Sands; William B. Ershler; Dennis Ledford
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AAPS workshop report: Strategies to address therapeutic protein-drug interactions during clinical development
AAPS Journal, ISSN: 15507416
Sandhya Girish; Steven W Martin; Mark C Peterson; Zhang; Hong Zhao; Joseph P. Balthasar; Raymond Evers; Honghui Zhou; Min Zhu; Lewis Klunk; Chao Han; Eva Gil Berglund; Huang; Amita Joshi
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Switchable Proteins and Channels
Molecular Switches, Second Edition,
Matthew Volgraf; Matthew Banghart; Dirk Trauner
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Differential regulation of mast cell degranulation versus cytokine secretion by the actin regulatory proteins Coronin1a and Coronin1b
Journal of Experimental Medicine, ISSN: 00221007 15409538
Niko Föger; André Jenckel; Zane Orinska; Kyeong-Hee Lee; Andrew A. Chan; Silvia Bulfone-Paus
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CCBE1 Is essential for mammalian lymphatic vascular development and enhances the lymphangiogenic effect of vascular endothelial growth factor-c in vivo
Circulation Research, ISSN: 00097330 15244571
Frank L. Bos; Maresa Caunt; Josi Peterson-Maduro; Lara Planas-Paz; Joe Kowalski; Terhi Karpanen; Andreas Van Impel; Raymond K. Tong; James A. Ernst; Jeroen Korving; Johan H. Van Es; Eckhard Lammert; Henricus J. Duckers; Stefan Schulte-Merker
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The notch1-Dll4 signaling pathway regulates mouse postnatal lymphatic development
Blood, ISSN: 15280020 00064971
Kyle Niessen; Gu Zhang; John B.B. Ridgway; Hao Chen; Ganesh Kolumam; Christian W. Siebel; Minhong Yan
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Recognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complex
EMBO Journal, ISSN: 02614189 14602075
Matthew L Bentley; Jacob E. Corn; Ken Dong; Qui Phung; Tommy K. Cheung; Andrea G Cochran
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miR-221/222 targeting of trichorh inophalangeal 1 (TRPS1) promotes epithelial-to-mesenchymal transition in breast cancer
Science Signaling, ISSN: 19450877 19379145
Susanna Y. Stinson; Lackner; Alex T. Adai; Nancy Yu; Hyo-Jin Kim; Carol O'Brien; Jill M. Spoerke; Suchit Jhunjhunwala; Zachary Boyd; Thomas Januario; Robert J. Newman; Peng Yue; Richard Bourgon; Zora Modrusan; Howard M. Stern; Søren Warming; Frederic J. De Sauvage; Lukas Amler; Ru-Fang Yeh; David Dornan
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Dlx6 regulates molecular properties of the striatum and central nucleus of the amygdala
Journal of Comparative Neurology, ISSN: 00219967 10969861
Bei Wang; Thomas Lufkin; John L. R. Rubenstein
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Antiviral activity of danoprevir (ITMN-191/RG7227) in combination with pegylated interferon α-2a and ribavirin in patients with hepatitis C
Journal of Infectious Diseases, ISSN: 00221899
Nicole Forestier; Dominique Larrey; Marcellin; Dominique Guyader; Alain Patat; Régine Rouzier; Patrick F. Smith; Xiaoli Qin; Sharlene R. Lim; Williamson Bradford; Steven Porter; Scott D. Seiwert; Stefan Zeuzem
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Live-cell microscopy reveals small molecule inhibitor effects on MAPK pathway dynamics
PLoS ONE, ISSN: 19326203
Daniel J Anderson; Jenni K. Durieux; Kyung Song; Ryan Alvarado; Peter K Jackson; Georgia Hatzivassiliou; Mary J. C. Ludlam
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Preparation of distinct ubiquitin chain reagents of high purity and yield
Structure, ISSN: 09692126 18784186
Ken Dong; Elizabeth Helgason; Christine Yu; Lilian Phu; David Arnott; Ivan Bosanac; Deanne M. Compaan; Oscar W Huang; Anna V. Fedorova; Donald S. Kirkpatrick; Sarah G. Hymowitz; Erin C. Dueber
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Isolation and characterization of therapeutic antibody charge variants using cation exchange displacement chromatography
Journal of Chromatography A, ISSN: 00219673 18733778
Taylor Zhang; Justin Bourret; Tony Cano
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Membrane targeting of palmitoylated Wnt and Hedgehog revealed by chemical probes
FEBS Letters, ISSN: 00145793 18733468
Xinxin Gao; Natalia Arenas-Ramirez; Suzie J. Scales; Rami N. Hannoush
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A delicate dance: Host response to mycobacteria
Current Opinion in Immunology, ISSN: 09527915 18790372
Kassidy K. Huynh; Shilpa A. Joshi; Eric J. Brown
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Sustained benefits from ranibizumab for macular edema following branch retinal vein occlusion: 12-month outcomes of a phase III study
Ophthalmology, ISSN: 01616420 15494713
David M. Brown; Peter A. Campochiaro; Robert B. Bhisitkul; Allen C. Ho; Sarah Gray; Namrata Saroj; Anthony P. Adamis; Roman G. Rubio; Wendy Yee Murahashi
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Notch3 signalling promotes tumour growth in colorectal cancer
Journal of Pathology, ISSN: 00223417 10969896
Valentina Serafin; Luca Persano; Lidia Moserle; Giovanni Esposito; Margherita Ghisi; Matteo Curtarello; Laura Bonanno; Massimo Masiero; Domenico Ribatti; Michael Stürzl; Elisabeth Naschberger; Roland S Croner; Adrian M. Jubb; Adrian L. Harris; Koeppen; Alberto Amadori; Stefano Indraccolo
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Research outcomes and recommendations for the assessment of progression in cancer clinical trials from a PhRMA working group
European Journal of Cancer, ISSN: 09598049 18790852
Stone; Bushnell; Denne; Daniel J. Sargent; Amit; Chen; Bailey-Iacona; Jeffrey D. Helterbrand; Williams
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Blinded independent central review of progression in cancer clinical trials: Results from a meta-analysis
European Journal of Cancer, ISSN: 09598049 18790852
Amit; Mannino; Stone; Bushnell; Denne; Jeffrey D. Helterbrand; Hans Ulrich Burger
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