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Publications

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DISPLAYING 8801 - 8850 OF 15394 RESULTS

Template proteogenomics: Sequencing whole proteins using an imperfect database
Molecular and Cellular Proteomics, ISSN: 15359476
Natalie E. Castellana; Victoria Pham; David Arnott; Jennie R. Lill; Vineet Bafna
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Modeling the efficacy of trastuzumab-DM1, an antibody drug conjugate, in mice
Journal of Pharmacokinetics and Pharmacodynamics, ISSN: 1567567X
Nelson L'ntshotsholé Jumbe; Yan Xin; Douglas Leipold; Lisa Crocker; Dugger; Elaine Mai; Mark X. Sliwkowski; Fielder; Jay Tibbitts
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Principal component analysis of general patterns of HIV-1 replicative fitness in different drug environments
Epidemics, ISSN: 17554365
João Martins; Colombe Chappey; Mojgan Haddad; Jeannette M. Whitcomb; Eric Stawiski; Christos J. Petropoulos; Sebastian Bonhoeffer
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Assessing therapeutic responses in Kras mutant cancers using genetically engineered mouse models
Nature Biotechnology, ISSN: 10870156 15461696
Mallika Singh; Anthony Lima; Rafael Molina; Patricia Hamilton; Anne C. Clermont; Vidusha Devasthali; Jennifer D. Thompson; Jason H. Cheng; Hani Bou-Reslan; Calvin Ho; Tim C. Cao; Chingwei V. Lee; Michelle Nannini; Fuh; Richard A. D. Carano; Koeppen; Ron Yu; William F. Forrest; Greg D. Plowman; Leisa Johnson
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Superior in vivo efficacy of afucosylated trastuzumab in the treatment of HER2-amplified breast cancer
Cancer Research, ISSN: 00085472 15387445
Teemu T. Junttila; Kathryn Parsons; Christine Olsson; Yanmei Lu; Yan Xin; Julie Theriault; Lisa Crocker; Oliver Pabonan; Tomasz K. Baginski; Meng; Klara Totpal; Robert F. Kelley; Mark X. Sliwkowski
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Antibodies specific for a segment of human membrane IgE deplete IgE-producing B cells in humanized mice
Journal of Clinical Investigation, ISSN: 00219738 15588238
Hans D. Brightbill; Surinc Er Jeet; Zhonghua Lin; Donghong Yan; Meijuan Zhou; Martha Tan; Allen Nguyen; Sherry Yeh; Donnie Delarosa; Leong; Wong; Chen; Ultsch; Luis; Sree R. Ramani; Janet Jackman; Lino C. Gonzalez Jr.; Dennis; Anan Chuntharapai; Laura DeForge; Meng; Min Xu; Eigenbrot; Wyne P. Lee; Refino; Mercedesz Balazs; Lawren C. Wu
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Mining manufacturing data for discovery of high productivity process characteristics
Journal of Biotechnology, ISSN: 01681656 18734863
Salim Charaniya; Huong Le; Huzefa Rangwala; Mills; Kevin Johnson; George Karypis; Hu
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First-year response to rhGH therapy in children with CKD: A National Cooperative Growth Study Report
Pediatric Nephrology, ISSN: 0931041X
John D. Mahan; Bradley A. Warady; James W. Frane; Rosenfeld; Rita D. Swinford; Barbara M. Lippe; Daniel Aaron Davis
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Blood test can replace invasive heart biopsy
Managed Care, ISSN: 10623388
Thomas Morrow
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Epithelial mesenchymal transition traits in human breast cancer cell lines parallel the CD44HI/CD24lO/-stem cell phenotype in human breast cancer
Journal of Mammary Gland Biology and Neoplasia, ISSN: 10833021
Tony Blick; Honor Hugo; Edwin Widodo; Mark Waltham; Cletus Pinto; Sendurai A. Mani; Robert A. Weinberg; Richard M. Neve; Marc E. Lenburg; Erik W. Thompson
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LRP2 in ependymal cells regulates BMP signaling in the adult neurogenic niche
Journal of Cell Science, ISSN: 00219533
Chandresh R. Gajera; Helena Emich; Oleg Lioubinski; Annabel Christ; Ruth Beckervordersandforth-Bonk; Kazuaki Yoshikawa; Sebastian Bachmann; Erik Ilsø Christensen; Magdalena Götz; Gerd Kempermann; Andrew S. Peterson; Thomas E. Willnow; Annette Hammes
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Development of rational drug combinations with investigational targeted agents
Oncologist, ISSN: 10837159 1549490X
Adam Clark; Matthew Ellis; Charles Erlichman; Stuart G. Lutzker; James Zwiebel
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The mutation spectrum revealed by paired genome sequences from a lung cancer patient
Nature, ISSN: 00280836 14764687
William Lee; Zhaoshi Jiang; Jinfeng Liu; Matthias Peter; Yinghui Guan; Stinson; Peng Yue; Yan Zhang; Krishna P. Pant; Deepali Bhatt; Connie Ha; Stephanie Johnson; Michael I. Kennemer; Sankar Mohan; Igor Nazarenko; Colin K. Watanabe; Andrew B. Sparks; David S. Shames; Robert Gentleman; Frederic J. De Sauvage; Howard M. Stern; Ajay Pandita; Dennis G. Ballinger; Radoje Drmanac; Zora Modrusan; Somasekar Seshagiri; Zemin Zhang
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Trafficking guidance receptors
Cold Spring Harbor Perspectives in Biology, ISSN: 19430264
Bettina Winckler; Ira Mellman
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Concerted action of wild-type and mutant TNF receptors enhances inflammation in TNF receptor 1-associated periodic fever syndrome
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Anna Simon; Heiyoung Park; Ravikanth Maddipati; Adrian A. Lobito; Ariel C. Bulua; Adrianna J. Jackson; Jae Jin Chae; Rachel Ettinger; Heleen D. De Koning; Anthony C. Cruz; Daniel L. Kastner; Hirsh Komarow; Richard M. Siegel
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Absent in melanoma 2 is required for innate immune recognition of Francisella tularensis
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Jonathan W. Jones; Nobuhiko Kayagaki; Petr Broz; Thomas Henry; Kim Newton; Karen M. O'Rourke; Salina Chan; Jennifer Dong; Yan Qu; Merone Roose-Girma; Vishva M. Dixit; Denise M. Monack
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Independent filtering increases detection power for high-throughput experiments
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Richard Bourgon; Robert Gentleman; Wolfgang Huber
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Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
Cancer Cell, ISSN: 15356108
Houtan Noushmehr; Daniel J. Weisenberger; Kristin Diefes; Phillips; Kanan Pujara; Benjamin P. Berman; Fei Pan; Christopher E. Pelloski; Erik P. Sulman; Krishna P.L. Bhat; Roel G.W. Verhaak; Katherine A. Hoadley; D. Neil Hayes; Charles M. Perou; Heather K. Schmidt; Li Ding; Richard K. Wilson; David Van Den Berg; Hui Shen; Henrik Bengtsson; Pierre Neuvial; Leslie Cope; Jonathan Buckley; James G. Herman; Stephen B. Baylin; Peter W. Laird; Kenneth D. Aldape
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Formation of a quinoneimine intermediate of 4-Fluoro- N -methylaniline by FMO1: Carbon oxidation plus defluorination
Chemical Research in Toxicology, ISSN: 0893228X 15205010
James Driscoll; Ignacio Aliagas; Jennifer J. Harris; Jason S Halladay; Sheerin Shahidi-Latham; Alan Deese; Nathaniel Segraves; S. Cyrus Khojasteh
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An adaptive design for phase II non-oncology dose selection clinical trials
Clinical Drug Investigation, ISSN: 11732563 11791918
Zheng Su
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Phosphatidylserine receptor Tim-4 is essential for the maintenance of the homeostatic state of resident peritoneal macrophages
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424 10916490
Kit Wong; Patricia A. Valdez; Christine Tan; Sherry Yeh; Hongo; Wenjun Ouyang
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Blood cytokines as biomarkers of in vivo toxicity in preclinical safety assessment: Considerations for their use
Toxicological Sciences, ISSN: 10966080 10960929
Jacqueline M. Tarrant
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The flexibility, quality and cost of single use recovery systems in bio-pharmaceutical drug production
American Pharmaceutical Review, ISSN: 10998012
Lindsay Leveen
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Targeting the insulin-like growth factor receptor-1R pathway for cancer therapy
Clinical Cancer Research, ISSN: 10780432
Jiping Zha; Lackner
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Novel micro-bioreactor high throughput technology for cell culture process development: Reproducibility and scalability assessment of fed-batch CHO cultures
Biotechnology and Bioengineering, ISSN: 00063592 10970290
Ashraf Amanullah; Jose Manuel Otero; Mark Mikola; Amy Hsu; Jinyou Zhang; John Aunins; H. Brett Schreyer; James A. Hope; A. Peter Russo
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Hepatocyte growth factor activator (HGFA): Molecular structure and interactions with HGFA inhibitor-1 (HAI-1)
FEBS Journal, ISSN: 1742464X 17424658
Eigenbrot; Rajkumar Ganesan; Daniel Kirchhofer
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Protein tyrosine phosphatase SHP-1 positively regulates TLR-induced IL-12p40 production in macrophages through inhibition of phosphatidylinositol 3-kinase
Journal of Leukocyte Biology, ISSN: 07415400
Delu Zhou; Cathleen A. Collins; Ping Wu; Eric J. Brown
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Assembly and biological and immunological properties of Newcastle disease virus-like particles
Journal of Virology, ISSN: 0022538X
Lori W. McGinnes; Homer Pantua; Jason P. Laliberte; Kathryn A. Gravel; Surbhi Jain; Trudy G. Morrison
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Recent advances in the genetics of systemic lupus erythematosus
Expert Review of Clinical Immunology, ISSN: 1744666X
Donna Thibault Flesher; Xin Sun; Timothy W. Behrens; Robert R. Graham; Lindsey A. Criswell
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Role of myeloid cells in vascular endothelial growth factor-independent tumor angiogenesis
Current Opinion in Hematology, ISSN: 10656251 15317048
Napoleone Ferrara
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Strategies for developing design spaces for viral clearance by anion exchange chromatography during monoclonal antibody production
Biotechnology Progress, ISSN: 87567938 15206033
Daniel M. Strauss; Tony Cano; Nick Cai; Heather Delucchi; Magdalena Plancarte; Daniel A. Coleman; Gregory S. Blank; Qi Chen; Bin Yang
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Physical activity and change in mammographic density
American Journal of Epidemiology, ISSN: 00029262 14766256
Shannon M. Conroy; Lesley Butler; Danielle Harvey; Ellen B. Gold; Barbara Sternfeld; Nina Oestreicher; Gail A. Greendale; Laurel A. Habel
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Efficacy and safety of retreatment in patients with rheumatoid arthritis with previous inadequate response to tumor necrosis factor inhibitors: Results from the SUNRISE trial
Journal of Rheumatology, ISSN: 0315162X
Philip J. Mease; Stanley B. Cohen; Norman B. Gaylis; Andrew Chubick; Alan T. Kaell; Maria Greenwald; Sunil Agarwal; Ming Yin; Ariella Kelman
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Signalling lessons from death receptors: The importance of cleavage
Nature Cell Biology, ISSN: 14657392
Vishva M. Dixit
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Detecting low level sequence variants in recombinant monoclonal antibodies
mAbs, ISSN: 19420862
Yi Yang; Alex Strahan; Charlene Li; Amy Shen; Hongbin Liu; Jun Ouyang; Viswanatham Katta; Kathleen Francissen; Boyan Zhang
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Host-detrimental role of Esx-1-mediated inflammasome activation in Mycobacterial infection
PLoS Pathogens, ISSN: 15537366 15537374
Fredric Carlsson; Janice Kim; Calin Dumitru; Kai H. Barck; Richard A. D. Carano; Mei Sun; Laurie Diehl; Eric J. Brown
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A20: From ubiquitin editing to tumour suppression
Nature Reviews Cancer, ISSN: 1474175X 14741768
Sarah G. Hymowitz; Ingrid E. Wertz
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Detection of protein-RNA complexes in Xenopus oocytes
Methods, ISSN: 10462023 10959130
Paul W. Huber; Wei-meng Zhao
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The RasGAP proteins Ira2 and neurofibromin are negatively regulated by Gpb1 in yeast and ETEA in humans
Molecular and Cellular Biology, ISSN: 02707306
Vernon T. Phan; Vivianne W. Ding; Fenglei Li; Robert J. Chalkley; Alma Burlingame; Frank McCormick
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Vaccinia H5 is a multifunctional protein involved in viral DNA replication, postreplicative gene transcription, and virion morphogenesis
Virology, ISSN: 00426822 10960341
Susan M. D'Costa; Travis W. Bainbridge; Sayuri E. Kato; Cindy Prins; Karen Kelley; Richard C. Condit
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Validation of cell density and viability assays using Cedex automated cell counter
Biologicals, ISSN: 10451056 10958320
Li-Chun Huang; Wendy Lin; Machiko Yagami; Daphne Tseng; Emily Miyashita-Lin; Nitasha Singh; Andy Lin; Shian-Jiun Shih
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Therapeutic antibodies for autoimmunity and inflammation
Nature Reviews Immunology, ISSN: 14741733
Andrew A. Chan; Paul J. Carter
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Prolonged endoplasmic reticulum stress promotes mislocalization of immunoglobulins to the cytoplasm
Molecular Immunology, ISSN: 01615890
Adi Drori; Shahram Misaghi; Joseph Haimovich; Martin Messerle; Boaz Tirosh
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Genome, epigenome and RNA sequences of monozygotic twins discordant for multiple sclerosis
Nature, ISSN: 00280836 14764687
Sergio E. Baranzini; Joann Mudge; Jennifer C. Van Velkinburgh; Pouya Khankhanian; Irina Khrebtukova; Neil A. Miller; Lu Zhang; Andrew D. Farmer; Callum J. Bell; Ryan W. Kim; Gregory D. May; Jimmy E. Woodward; Stacy J. Caillier; Joseph P. McElroy; Refujia Gomez; Marcelo J. Pando; Leonda E. Clendenen; Elena E. Ganusova; Faye D. Schilkey; Thiruvarangan Ramaraj; Omar A. Khan; Jim J. Huntley; Shujun Luo; Pui-Yan Kwok; Thomas D Wu; Gary P. Schroth; Jorge R. Oksenberg; Stephen L. Hauser; Stephen F. Kingsmore
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Reply to W. Wick et al
Journal of Clinical Oncology, ISSN: 0732183X 15277755
Henry S. Friedman; Michael D. Prados; Patrick Y. Wen; Tom Mikkelsen; David Schiff; Lauren E. Abrey; Alfred Yung; Nina Paleologos; Martin K. Nicholas; Randy Jensen; James Vredenburgh; Jane E. Huang; Maoxia Zheng; Timothy Cloughesy
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Ladder polyether synthesis via epoxide-opening cascades directed by a disappearing trimethylsilyl group
Journal of Organic Chemistry, ISSN: 00223263 15206904
Timothy P. Heffron; Graham L. Simpson; Estibaliz Merino; Timothy F. Jamison
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IL-17RC is required for IL-17A- and IL-17F-dependent signaling and the pathogenesis of experimental autoimmune encephalomyelitis
Journal of Immunology, ISSN: 00221767 15506606
Yan Hu; Naruhisa Ota; Ivan Peng; Refino; Dimitry Danilenko; Patrick Caplazi; Wenjun Ouyang
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Identification of GNE-477, a potent and efficacious dual PI3K/mTOR inhibitor
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Timothy P. Heffron; Megan Berry; Georgette M. Castanedo; Christine Chang; Irina Chuckowree; Jennafer Dotson; Adrian J. Folkes; Janet Gunzner; John Lesnick; Lewis; Simon Mathieu; Jim Nonomiya; Alan G. Olivero; Jodie Pang; David Peterson; Laurent Salphati; Deepak Sampath; Steve Sideris; Daniel P. Sutherlin; Vickie Tsui; Nan Chi Wan; Shumei Wang; Susan C. Wong; Bing-Yan Zhu
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A therapeutic anti-VEGF antibody with increased potency independent of pharmacokinetic half-life
Cancer Research, ISSN: 00085472 15387445
Yik Andy Yeung; Xiumin Wu; Arthur Reyes; Jean-Michel Vernes; Samantha Lien; John Lowe; Mauricio Maia; William F. Forrest; Meng; Lisa A. Damico; Napoleone Ferrara; Henry B. Lowman
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Therapeutic antibody targeting of individual Notch receptors
Nature, ISSN: 00280836 14764687
Yan Wu; Carol Cain-Hom; Lisa Choy; Thijs Hagenbeek; Gladys P. De Leon; Yongmei Chen; David Finkle; Rayna Venook; Xiumin Wu; John B.B. Ridgway; Dorreyah Schahin-Reed; Graham J. Dow; Amy Shelton; Scott Stawicki; Ryan J. Watts; Jeff Zhang; Robert Choy; Peter Howard; Lisa Kadyk; Minhong Yan; Jiping Zha; Christopher Callahan; Sarah G. Hymowitz; Christian W. Siebel
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