Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 9151 - 9200 OF 15394 RESULTS

Exon array profiling detects EML4-ALK fusion in breast, colorectal, and non-small cell lung cancers
Molecular Cancer Research, ISSN: 15417786
Eva Lin; Li Li; Yinghui Guan; Robert Soriano; Rivers; Sankar Mohan; Ajay Pandita; Zhijun Tang; Zora Modrusan
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Converting cancer mutations into therapeutic opportunities
EMBO Molecular Medicine, ISSN: 17574676 17574684
Thomas O'Brien; David Stokoe
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Design, synthesis and discovery of 1-(2-(6-chloro-3-methylsulfonyl)- naphthyl)-1H-pyrazole-5-carboxylamides as highly potent factor Xa inhibitors
Chemical and Pharmaceutical Bulletin, ISSN: 00092363 13475223
Zhaozhong J. Jia; Robert M. Scarborough; Penglie Zhang; Sherin Halfon; Ann Elizabeth Arfsten; Uma Sinha; Bing-Yan Zhu
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Clinical outcomes associated with bevacizumab-containing treatment of metastatic colorectal cancer: The BRiTE observational cohort study
Oncologist, ISSN: 10837159 1549490X
Kozloff; Marianne Ulcickas Yood; Jordan Berlin; Patrick J. Flynn; Fairooz F. Kabbinavar; David M. Purdie; Ashby; Wei Dong; Mary M. Sugrue; Grothey
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SKAP associates with kinetochores and promotes the metaphase-to-anaphase transition
Cell Cycle, ISSN: 15514005 15384101
Lin Fang; Akiko Seki; Guowei Fang
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T-helper type 2-driven inflammation defines major subphenotypes of asthma
American Journal of Respiratory and Critical Care Medicine, ISSN: 1073449X 15354970
Prescott G. Woodruff; Barmak Modrek; David F. Choy; Guiquan Jia; Abbas Alexander; Almut Ellwanger; Joseph R. Arron; Laura L. Koth; John V. Fahy
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Stimulant medication use and response to growth hormone therapy: An NCGS database analysis
Hormone Research, ISSN: 03010163
J. Paul Frindik; Alba Morales; John Fowlkes; Stephen F. Kemp; Kathryn Thrailkill; Barbara M. Lippe; Ken Dana
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Disruption of nNOS-PSD95 protein-protein interaction inhibits acute thermal hyperalgesia and chronic mechanical allodynia in rodents
British Journal of Pharmacology, ISSN: 00071188 14765381
Florio; Loh; Huang; Iwamaye; Kitto; Fowler; Treiberg; Hayflick; Walker; Fairbanks; Lai
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Development of a high throughput protein a well-plate purification method for monoclonal antibodies
Biotechnology Progress, ISSN: 87567938
Jennifer Hopp; Ross Pritchett; Maria R. Darlucio; Junfen Ma; Judy H. Chou
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Response to Charlton et al.
Birth Defects Research Part A - Clinical and Molecular Teratology, ISSN: 15420752 15420760
Angela E. Scheuerle; Vani X. Vannappagari; Mary K. Miller
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Laplace's approximation for relative risk frailty models
Lifetime Data Analysis, ISSN: 13807870
Shibao Feng; Lei Nie; Robert A. Wolfe
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The prioritization of cancer antigens: A National Cancer Institute pilot project for the acceleration of translational research
Clinical Cancer Research, ISSN: 10780432
Martin A. Cheever; James P. Allison; Andrea Stern Ferris; Olivera J. Finn; Benjamin M. Hastings; Toby T. Hecht; Ira Mellman; Sheila A. Prindiville; Jaye L. Viner; Louis M. Weiner; Lynn M. Matrisian
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A Phase IIIb Study to Evaluate the Safety of Ranibizumab in Subjects with Neovascular Age-related Macular Degeneration
Ophthalmology, ISSN: 01616420
David S. Boyer; Jeffrey S. Heier; David M. Brown; Steve Francom; Tsontcho Ianchulev; Roman G. Rubio
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Disruption of nNOS-PSD95 protein-protein interaction inhibits acute thermal hyperalgesia and chronic mechanical allodynia in rodents
British Journal of Pharmacology, ISSN: 00071188 14765381
Florio; Christine Loh; Huang; Iwamaye; Kitto; Fowler; Treiberg; Hayflick; Walker; Fairbanks; Lai
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Techniques for time-efficient isolation of human skin dendritic cell subsets and assessment of their antigen uptake capacity
Journal of Immunological Methods, ISSN: 00221759
Emily Bond; William C. Adams; Anna Smed-Sörensen; Kerrie J. Sandgren; Leif Perbeck; Anette Hofmann; Jan Andersson; Karin Loré
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Effects of S1 cleavage on the structure, surface export, and signaling activity of human Notch1 and Notch2
PLoS ONE, ISSN: 19326203
Wendy R. Gordon; Didem Vardar-Ulu; Sarah L'Heureux; Todd Ashworth; Michael J. Malecki; Cheryll Sanchez-Irizarry; Debbie G. McArthur; Gavin Histen; Jennifer L. Mitchell; Jon C. Aster; Stephen C. Blacklow
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A highly annotated whole-genome sequence of a Korean individual
Nature, ISSN: 00280836 14764687
Jong-Il Kim; Young Seok Ju; Hansoo Park; Sheehyun Kim; Seonwook Lee; Jae-Hyuk Yi; Joann Mudge; Neil A. Miller; Dongwan Hong; Callum J. Bell; Hye-Sun Kim; In-Soon Chung; Woo-Chung Lee; Ji-Sun Lee; Seung-Hyun Seo; Ji-Young Yun; Hyun Nyun Woo; Heewook Lee; Dongwhan Suh; Seungbok Lee; Hyun-Jin Kim; Maryam Yavartanoo; Minhye Kwak; Ying Zheng; Mi Kyeong Lee; Hyunjun Park; Jeong Yeon Kim; Omer Gokcumen; Ryan E. Mills; Alexander Wait Zaranek; Joseph Thakuria; Xiaodi Wu; Ryan W. Kim; Jim J. Huntley; Shujun Luo; Gary P. Schroth; Thomas D Wu; Hyeran Kim; Kap-Seok Yang; Woong-Yang Park; Hyungtae Kim; George M. Church; Charles Lee; Stephen F. Kingsmore; Jeong-Sun Seo
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Validation of tangential flow filtration in biopharmaceutical applications task force
PDA Journal of Pharmaceutical Science and Technology, ISSN: 10797440
Chris Antoniou; Neil Bingham; Glen Bolton; Chris Bussineau; Michael Dosmar; Chithkala Harinarayan; Robert W. Juffras; James Klein; Peter Levy; Richard V. Levy; Mike Mulcare; Jon Petrone; Jon Romero; Ganesh Vedantham; Robert Velcheck
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Investigation of sample preparation artifacts formed during the enzymatic release of N-linked glycans prior to analysis by capillary electrophoresis
Analytical Chemistry, ISSN: 00032700
Yong Liu; Oscar Salas-Solano; Lynn Gennaro
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Identification of cell culture conditions to control N-glycosylation site-occupancy of recombinant glycoproteins expressed in CHO cells
Biotechnology and Bioengineering, ISSN: 00063592 10970290
Martin Gawlitzek; Michael Estacio; Tobias Fürch; Robert Kiss
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BCL6 cooperates with CD40 stimulation and loss of p53 function to rapidly transform primary B cells
International Journal of Cancer, ISSN: 00207136 10970215
Saritha Kusam; Veerendra Munugalavadla; Deepali Sawant; Alexander Dent
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A multi-tiered analytical approach for the analysis and quantitation of high-molecular-weight aggregates in a recombinant therapeutic glycoprotein
AAPS Journal, ISSN: 15507416
Heather Hughes; Charles Morgan; Elizabeth Brunyak; Kristen Barranco; Emily Cohen; Tim Edmunds; Karen Lee
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The Mammalian Cos2 Homolog Kif7 Plays an Essential Role in Modulating Hh Signal Transduction during Development
Current Biology, ISSN: 09609822
Setsu Endoh-Yamagami; Marie Evangelista; Deanna G. Wilson; Xiaohui Wen; Jan-Willem Theunissen; Khanhky Phamluong; Matti Davis; Suzie J. Scales; Mark J. Solloway; Frederic J. De Sauvage; Andrew S. Peterson
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Microarray analysis of RNA extracted from formalin-fixed, paraffin-embedded and matched fresh-frozen ovarian adenocarcinomas
BMC Medical Genomics, ISSN: 17558794
Grazyna Fedorowicz; Steve Guerrero; Thomas D Wu; Zora Modrusan
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High-resolution analysis of copy number alterations and associated expression changes in ovarian tumors
BMC Medical Genomics, ISSN: 17558794
Matthias Peter; Lawrence S. Hon; Joshua S. Kaminker; John Chant; Zemin Zhang
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Molecular predictors of response to a humanized anti-insulin-like growth factor-I receptor monoclonal antibody in breast and colorectal cancer
Molecular Cancer Therapeutics, ISSN: 15357163
Jiping Zha; Carol O'Brien; Heidi Savage; Huw; Fiona Zhong; Berry; Gail L. Phillips; Luis; Guy Cavet; Xiaolan Hu; Lukas Amler; Lackner
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Health benefit costs and absenteeism due to insomnia from the employer's perspective: A retrospective, case-control, database study
Journal of Clinical Psychiatry, ISSN: 01606689
Nathan L. Kleinman; Richard A. Brook; Justin Doan; Arthur K. Melkonian; Robert W. Baran
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Antibody binding to a tethered vesicle assembly using QCM-D
Analytical Chemistry, ISSN: 00032700
Ankit Patel; Kay K. Kanazawa; Curtis W. Frank
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Churg-Strauss syndrome in patients treated with omalizumab
Chest, ISSN: 19313543 00123692
Michael E. Wechsler; Dennis A. Wong; Mary K. Miller; Lisa Lawrence-Miyasaki
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Paracrine hedgehog signaling in cancer
Cancer Research, ISSN: 00085472 15387445
Jan-Willem Theunissen; Frederic J. De Sauvage
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Subcellular compartmentalization of FADD as a new level of regulation in death receptor signaling
FEBS Journal, ISSN: 1742464X 17424658
Niko Föger; Silvia Bulfone-Paus; Andrew A. Chan; Kyeong-Hee Lee
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European population substructure is associated with mucocutaneous manifestations and autoantibody production in systemic lupus erythematosus
Arthritis and Rheumatism, ISSN: 00043591 15290131
Sharon A. Chung; Tian; Kimberly E. Taylor; Annette T. Lee; Ward Ortmann; Geoffrey Hom; Robert R. Graham; Joanne Nititham; Jennifer A. Kelly; Jean Morrisey; Hui Wu; Hong Yin; Marta E. Alarcón-Riquelme; Betty P. Tsao; John B. Harley; Patrick M. Gaffney; Kathy L. Moser; Manzi; Michelle Petri; Peter K. Gregersen; Carl D. Langefeld; Timothy W. Behrens; Michael F. Seldin; Lindsey A. Criswell
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A phase IB trial of intravenous INO-1001 plus oral temozolomide in subjects with unresectable stage-III or IV melanoma
Cancer Investigation, ISSN: 07357907 15324192
Agop Y. Bedikian; Nicholas E. Papadopoulos; Kevin B. Kim; Wen-Jen Hwu; Jade Homsi; Michelle R. Glass; Suzanne Cain; Patrick J. Rudewicz; Laurent Vernillet; Patrick Hwu
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Oncogenic activating mutations are associated with local copy gain
Molecular Cancer Research, ISSN: 15417786
Barmak Modrek; Lin Ge; Ajay Pandita; Eva Lin; Sankar Mohan; Peng Yue; Steve Guerrero; William M. Lin; Thinh Q. Pham; Zora Modrusan; Somasekar Seshagiri; Howard M. Stern; Waring; Levi A. Garraway; John Chant; David Stokoe; Guy Cavet
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Molecular predictors of response to a humanized anti-insulin-like growth factor-I receptor monoclonal antibody in breast and colorectal cancer
Molecular Cancer Therapeutics, ISSN: 15357163
Jiping Zha; Carol O'Brien; Heidi Savage; Huw; Fiona Zhong; Berry; Gail L. Phillips; Luis; Guy Cavet; Hu; Lukas Amler; Lackner
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FAM29A, a target of Plk1 regulation, controls the partitioning of NEDD1 between the mitotic spindle and the centrosomes
Journal of Cell Science, ISSN: 00219533
Hui Zhu; Kayleen Fang; Guowei Fang
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Prostate-specific Klf6 inactivation impairs anterior prostate branching morphogenesis through increased activation of the Shh pathway
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Ching Ching Leow; Bu-Er Wang; Ross; Sara M. Chan; Jiping Zha; Richard A. D. Carano; Gretchen D. Frantz; Michael M. Shen; Frederic J. De Sauvage; Gao
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Development of a microarray platform for FFPET profiling: Application to the classification of human tumors
Journal of Translational Medicine, ISSN: 14795876
Sven Duenwald; Mingjie Zhou; Yanqun Wang; Serguei Lejnine; Amit Kulkarni; Jaime Graves; Ryan Smith; John C. Castle; George Tokiwa; Bernard M. Fine; Hongyue Dai; Thomas Fare; Matthew Marton
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Phosphorylation of a borealin dimerization domain is required for proper chromosome segregation
Biochemistry, ISSN: 00062960
Eric Bourhis; Andreas Lingel; Qui Phung; Wayne J. Fairbrother; Andrea G Cochran
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Comparative assessment of substrates and activity based probes as tools for non-invasive optical imaging of cysteine protease activity
PLoS ONE, ISSN: 19326203
Galia Blum; Robby M. Weimer; Laura E. Edgington; Walter Adams; Matthew Bogyo
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Membrane proteins follow multiple pathways to the basolateral cell surface in polarized epithelial cells
Journal of Cell Biology, ISSN: 00219525 00219525
Glen A. Farr; Mike Hull; Ira Mellman; Michael J. Caplan
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Two-dimensional liquid chromatographic methods to examine phenylboronate interactions with recombinant antibodies
Journal of Chromatography A, ISSN: 00219673
Boyan Zhang; Sean Mathewson; Huifen Chen
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Navigating the Deubiquitinating Proteome with a CompPASS
Cell, ISSN: 00928674
Peter K Jackson
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Type I interferon receptor controls B-cell expression of nucleic acid-sensing Toll-like receptors and autoantibody production in a murine model of lupus
Arthritis Research and Therapy, ISSN: 14786354 14786362
Donna L. Thibault; Kareem L. Graham; Lowen Y. Lee; Imelda Balboni; Paul J. Hertzog; Paul J. Utz
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IL-33 Raises Alarm
Immunity, ISSN: 10747613
Lamkanfi; Vishva M. Dixit
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Imaging the lipidome: ω-alkynyl fatty acids for detection and cellular visualization of lipid-modified proteins
ACS Chemical Biology, ISSN: 15548929
Rami N. Hannoush; Natalia Arenas-Ramirez
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Antagonism of c-IAP and XIAP proteins is required for efficient induction of cell death by small-molecule IAP antagonists
ACS Chemical Biology, ISSN: 15548929
Chudi O. Ndubaku; Eugene Varfolomeev; Lan Wang; Zobel; Kevin Lau; Linda O. Elliott; Brigitte Maurer; Anna V. Fedorova; Jasmin N. Dynek; Michael F. T. Koehler; Sarah G. Hymowitz; Vickie Tsui; Deshayes; Wayne J. Fairbrother; Flygare; Domagoj Vucic
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Assigning large proteins in the solid state: A MAS NMR resonance assignment strategy using selectively and extensively 13C-labelled proteins
Journal of Biomolecular NMR, ISSN: 09252738 15735001
Victoria A. Higman; Jeremy Flinders; Matthias Hiller; Stefan Jehle; Stefan Markovic; Sebastian Fiedler; Barth-Jan van Rossum; Hartmut Oschkinat
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Clinical and immunogenetic prognostic factors for radiographic severity in ankylosing spondylitis
Arthritis Care and Research, ISSN: 21514658
Michael M. Ward; Matthew R. Hendrey; James D. Malley; Thomas J. Learch; John C. Davis; John D. Reveille; Michael Weisman
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Fear of commitment: Hes1 protects quiescent fibroblasts from irreversible cellular fates
Cell Cycle, ISSN: 15514005 15384101
Liyun Sang; Hilary A. Coller
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