Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10001 - 10050 OF 15396 RESULTS

Nerve growth factor mediates steroid-resistant inflammation in respiratory syncytial virus infection
Pediatric Pulmonology, ISSN: 87556863 10990496
Lida Mohtasham; Alexander Auais; Giovanni Piedimonte
View on Scopus
A pilot study of tumor necrosis factor inhibition in erosive/inflammatory osteoarthritis of the hands
Journal of Rheumatology, ISSN: 0315162X
Molly D. Magnano; Eliza F. Chakravarty; Corrie Broudy; Lorinda Chung; Ariella Kelman; Jennifer Hillygus; Mark C. Genovese
View on Scopus
Do deaf and hard of hearing youth need antitobacco education?
American Annals of the Deaf, ISSN: 0002726X
Barbara A. Herman; Leanne Streja; Coen A. Bernaards; Elizabeth A. Eckhardt; Heidi B. Kleiger; Lauren Maucere; Glenn Wong; Shari Barkin; Roshan Bastani
View on Scopus
Presence of methicillin resistant Staphylococcus aureus in respiratory cultures from cystic fibrosis patients is associated with lower lung function
Pediatric Pulmonology, ISSN: 87556863 10990496
Clement L. Ren; Morgan; Michael W. Konstan; Michael S. Schechter; Wagener; Kathryn A. Fisher; Warren E. Regelmann
View on Scopus
Exploring and designing protein function with restricted diversity
Current Opinion in Chemical Biology, ISSN: 13675931
Sachdev S. Sidhu; Anthony A. Kossiakoff
View on Scopus
Dendritic cell vaccine hits FDA roadblock.
Managed Care, ISSN: 10623388
Thomas Morrow
View on Scopus
Real-world Evaluation of Asthma Control and Treatment (REACT): Findings from a national Web-based survey
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Stephen P. Peters; Craig A. Jones; Tmirah Haselkorn; David R. Mink; David J. Valacer; Weiss
View on Scopus
The soluble Wnt receptor Frizzled8CRD-hFc inhibits the growth of teratocarcinomas in vivo
Cancer Research, ISSN: 00085472
Venita I. DeAlmeida; Li Miao; James A. Ernst; Koeppen; Paul G. Polakis; Bonnee Rubinfeld
View on Scopus
Characterization of protein-protein interactions critical for poliovirus replication: Analysis of 3AB and VPg binding to the RNA-dependent RNA polymerase
Journal of Virology, ISSN: 0022538X
Daniel M. Strauss; Deborah S. Wuttke
View on Scopus
Transitioning patients from efalizumab to alternative psoriasis therapies: Findings from an open-label, multicenter, Phase IIIb study
International Journal of Dermatology, ISSN: 00119059 13654632
Alan Menter; Tiffani K. Hamilton; Darryl P. Toth; Hoi M. Leung; Graham Wetherill; Brian Hennessey; Marvin Garovoy; Paul Kwon; David M. Pariser
View on Scopus
Structure of the catalytic domain of human polo-like kinase 1
Biochemistry, ISSN: 00062960
Michael Kothe; Darcy Kohls; Simon Low; Rocco Coli; Alan C. Cheng; Suzanne L. Jacques; Theresa L. Johnson; Lewis; Christine Loh; Jim Nonomiya; Alissa L. Sheils; Kimberly A. Verdries; Thomas A. Wynn; Cyrille Kuhn; Yuan-Hua Ding
View on Scopus
Armed antibodies targeting the mucin repeats of the ovarian cancer antigen, MUC16, are highly efficacious in animal tumor models
Cancer Research, ISSN: 00085472
Youjun Chen; Suzanna Clark; Wong; Yongmei Chen; Chen; Dennis; Luis; Fiona Zhong; Sheila Bheddah; Koeppen; Alvin Gogineni; Paul G. Polakis; William Mallet
View on Scopus
Targeting VEGF-A to treat cancer and age-related macular degeneration
Annual Review of Medicine, ISSN: 00664219
Napoleone Ferrara; Robert Mass; Claudio Campa; Robert Kim
View on Scopus
Krüppel-like transcription factor 13 regulates T lymphocyte survival in vivo
Journal of Immunology, ISSN: 00221767
Meixia Zhou; Lisa McPherson; Dongdong Feng; An Song; Chen Dong; Shu-Chen Lye; Lu Zhou; Xiaoyan Shi; Yong-Tae Ahn; Demin Wang; Carol Clayberger; Alan M. Krensky
View on Scopus
Loop anchor modification causes the population of an alternative native state in an SH3-like domain
Protein Science, ISSN: 09618368 1469896X
Jane A. Knappenberger; Juliette T.J. Lecomte
View on Scopus
Targeted and untargeted CD137L fusion proteins for the immunotherapy of experimental solid tumors
Clinical Cancer Research, ISSN: 10780432
Nan Zhang; Rebecca E. Sadun; Robyn S. Arias; Meg L. Flanagan; Suzanne M. Sachsman; Yu-Chih Nien; Leslie A. Khawli; Peisheng Hu; Alan L. Epstein
View on Scopus
Quantitative translational pharmacology for monoclonal antibody dose and dose-schedule determination
American Pharmaceutical Review, ISSN: 10998012
Nelson L'ntshotsholé Jumbe
View on Scopus
Monoclonal antibody now available to prevent red blood cell breakdown.
Managed Care, ISSN: 10623388
Thomas Morrow
View on Scopus
Selective clearance of glycoforms of a complex glycoprotein pharmaceutical caused by terminal N-acetylglucosamine is similar in humans and cynomolgus monkeys
Glycobiology, ISSN: 09596658 14602423
Andrew J.S. Jones; Damon I. Papac; Chin; Rodney Keck; Sharon A. Baughman; Yvonne S. Lin; Johannes Kneer; John E. Battersby
View on Scopus
Demographic and clinical characteristics of children and adolescents with severe or difficult-to-treat asthma
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Bradley E. Chipps; Stanley J. Szefler; F. Estelle R. Simons; Tmirah Haselkorn; David R. Mink; Yamo Deniz; June H. Lee
View on Scopus
Full-length antibodies on display
Nature Biotechnology, ISSN: 10870156 15461696
Sachdev S. Sidhu
View on Scopus
Quantifying the treatment effect explained by markers in the presence of measurement error
Statistics in Medicine, ISSN: 02776715 10970258
Somnath Sarkar; Yongming Qu
View on Scopus
Role for Msh5 in the regulation of Ig class switch recombination
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Hideharu Sekine; Ricardo C. Ferreira; Qiang Pan-Hammarström; Robert R. Graham; Beth Ziemba; Sandra S. De Vries; Jiabin Liu; Keli Hippen; Thearith Koeuth; Ward Ortmann; Akiko Iwahori; Margaret K. Elliott; Steven Offer; Cara Skon; Likun Du; Jill Novitzke; Annette T. Lee; Nianxi Zhao; Joshua D. Tompkins; David Altshuler; Peter K. Gregersen; Charlotte Cunningham-Rundles; Reuben S. Harris; Chengtao Her; David L. Nelson; Lennart Hammarström; Gary S. Gilkeson; Timothy W. Behrens
View on Scopus
Spectroscopic evaluation of the stabilization of humanized monoclonal antibodies in amino acid formulations
International Journal of Pharmaceutics, ISSN: 03785173
Fei Tian; C. Russell Middaugh; Tom Offerdahl; Eric Munson; Samir Sane; J. Howard Rytting
View on Scopus
The BH3-Only Protein Bid Is Dispensable for DNA Damage- and Replicative Stress-Induced Apoptosis or Cell-Cycle Arrest
Cell, ISSN: 00928674
Kaufmann; Lin Tai; Paul G. Ekert; David C.S. Huang; Fiona Norris; Ralph K. Lindemann; Ricky W. Johnstone; Vishva M. Dixit; Andreas Strasser
View on Scopus
ElaD, a deubiquitinating protease expressed by E. coli
PLoS ONE, ISSN: 19326203
André Catic; Shahram Misaghi; Gregory A. Korbel; Hidde L. Ploegh
View on Scopus
Netrin-1/DCC signaling in commissural axon guidance requires cell-autonomous expression of heparan sulfate
Journal of Neuroscience, ISSN: 02706474 02706474
Yoshihiro Matsumoto; Fumitoshi Irie; Masaru Inatani; Marc Tessier-Lavigne; Yu Yamaguchi
View on Scopus
Ala657 and conserved active site residues promote fibroblast activation protein endopeptidase activity via distinct mechanisms of transition state stabilization
Biochemistry, ISSN: 00062960
Sarah A. Meadows; Conrad Yap Edosada; Mark Mayeda; Thuy Tran; Quan; Helga Raab; Wiesmann; Beni B. Wolf
View on Scopus
Three functional variants of IFN regulatory factor 5 (IRF5) define risk and protective haplotypes for human lupus
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Robert R. Graham; Chieko Kyogoku; Snaevar Sigurdsson; Irina A. Vlasova; Leela R. L. Davies; Emily C. Baechler; Robert M. Plenge; Thearith Koeuth; Ward Ortmann; Geoffrey Hom; Jason W. Bauer; Clarence Gillett; Noel Burtt; Deborah S. Cunninghame Graham; Robert Onofrio; Michelle Petri; Iva Gunnarsson; Elisabet Svenungsson; Lars Rönnblom; Gunnel Nordmark; Peter K. Gregersen; Kathy L. Moser; Patrick M. Gaffney; Lindsey A. Criswell; Timothy J. Vyse; Ann-Christine Syvänen; Paul R. Bohjanen; Mark J. Daly; Timothy W. Behrens; David Altshuler
View on Scopus
Assays for the Release of Viral Vector Gene Therapy Products for Human Clinical Trials
Concepts in Genetic Medicine,
Flavia Borellini
View on Scopus
The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: Regulation of Rho GTPase recruitment to the leading edge
Oncogene, ISSN: 09509232 14765594
Dow; Kauffman; Caddy; Andrew S. Peterson; Jane; Russell; Humbert
View on Scopus
Glycosylphosphatidylinositol-Anchored High-Density Lipoprotein-Binding Protein 1 Plays a Critical Role in the Lipolytic Processing of Chylomicrons
Cell Metabolism, ISSN: 15504131
Anne P. Beigneux; Brandon S.J. Davies; Peter Gin; Michael M. Weinstein; Emily Farber; Xin Qiao; Franklin V. Peale Jr.; Bunting; Rosemary L. Walzem; Jinny S. Wong; William S. Blaner; Zhi-Ming Ding; Kristan Melford; Nuttaporn Wongsiriroj; Xiao Shu; Frederic J. De Sauvage; Robert O. Ryan; Loren G. Fong; André Bensadoun; Stephen G. Young
View on Scopus
Plexin-B2 controls the development of cerebellar granule cells
Journal of Neuroscience, ISSN: 02706474 02706474
Roland H. Friedel; Géraldine Kerjan; Helen Rayburn; Ulrich Schüller; Constantino Sotelo; Marc Tessier-Lavigne; Alain Chedotal
View on Scopus
Swapping the gene-specific and regional silencing specificities of the Hst1 and Sir2 histone deacetylases
Molecular and Cellular Biology, ISSN: 02707306
Janet Mead; Ron McCord; Laura Youngster; Mandakini Sharma; Marc R. Gartenberg; Andrew K. Vershon
View on Scopus
Vasorelaxation induced by vascular endothelial growth factor in the human internal mammary artery and radial artery
Vascular Pharmacology, ISSN: 15371891
Wei Wei; Zhi-Wu Chen; Qin Yang; Hongkui Jin; Anthony Furnary; Xiao-Qiang Yao; Anthony P. C. Yim; Guo-Wei He
View on Scopus
Vascular targeting via caveolae
Nature Biotechnology, ISSN: 10870156 15461696
Kristy Red-Horse; Napoleone Ferrara
View on Scopus
Basic helix-loop-helix transcription factor heterocomplex of Yas1p and Yas2p regulates cytochrome P450 expression in response to alkanes in the yeast Yarrowia lipolytica
Eukaryotic Cell, ISSN: 15359778
Setsu Endoh-Yamagami; Kiyoshi Hirakawa; Daisuke Morioka; Ryouichi Fukuda; Akinori Ohta
View on Scopus
High-throughput automated system for crystallizing membrane proteins in lipidic mesophases
IEEE Transactions on Automation Science and Engineering, ISSN: 15455955
Avinash Peddi; Lalitha Muthusubramaniam; Yuan F. Zheng; Vadim Cherezov; Yohann Misquitta; Martin Caffrey
View on Scopus
Dimethylfumarate induces immunosuppression via glutathione depletion and subsequent induction of heme oxygenase 1
Journal of Investigative Dermatology, ISSN: 0022202X 15231747
Joachim C.U. Lehmann; Joanna J. Listopad; Christine U. Rentzsch; Frederik H. Igney; Arne Von Bonin; Hartwig H. Hennekes; Khusru Asadullah; Wolf-Dietrich F. Docke
View on Scopus
The 620W allele is the PTPN22 genetic variant conferring susceptibility to RA in a Dutch population
Rheumatology, ISSN: 14620324 14620332
Wesoly; Hu; Thabet; Chang; Uh; Allaart; Toes; Houwing-Duistermaat; Begovich; Tom W. J. Huizinga
View on Scopus
Regulation of myeloid progenitor cell proliferation/survival by IL-31 receptor and IL-31
Experimental Hematology, ISSN: 0301472X
Hal E. Broxmeyer; Ji Li; Giao Hangoc; Scott Cooper; Wen Tao; Charlie Mantel; Barbara Graham-Evans; Nico Ghilardi; Frederic J. De Sauvage
View on Scopus
ASC, Ipaf and Cryopyrin/Nalp3: bona fide intracellular adapters of the caspase-1 inflammasome
Microbes and Infection, ISSN: 12864579 1769714X
Sanjeev Mariathasan
View on Scopus
Design space for biotech products
BioPharm International, ISSN: 1542166X
Anurag S. Rathore; Ron Branning; Doug Cecchini
View on Scopus
Phosphorylation of a Wiscott-Aldrich syndrome protein-associated signal complex is critical in osteoclast bone resorption
Journal of Biological Chemistry, ISSN: 00219258 1083351X
Meenakshi A. Chellaiah; Dhandapani Kuppuswamy; Larry Lasky; Stefan Linder
View on Scopus
Species-dependent serum interference in a sandwich ELISA for Apo2L/TRAIL
Journal of Immunological Methods, ISSN: 00221759
Laura DeForge; Danny Shih; Derek Kennedy; Klara Totpal; Anan Chuntharapai; Bennett; Jason H. Drummond; Patricia Siguenza; Wai Lee T. Wong
View on Scopus
Robo1 and Robo2 cooperate to control the guidance of major axonal tracts in the mammalian forebrain
Journal of Neuroscience, ISSN: 02706474 02706474
Guillermina López-Bendito; Nuria Flames; Le Ma; Coralie Fouquet; Thomas Di Meglio; Alain Chedotal; Marc Tessier-Lavigne; Oscar Marín
View on Scopus
Utilizing the activation mechanism of serine proteases to engineer hepatocyte growth factor into a Met antagonist
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Daniel Kirchhofer; Michael T. Lipari; Santell; Karen L Billeci; Henry R. Maun; Wendy N. Sandoval; Paul Moran; John B.B. Ridgway; Eigenbrot; Lazarus
View on Scopus
Substrate tolerance of module 6 of the epothilone synthetase
Biochemistry, ISSN: 00062960
Martha Lovato Tse; R. Edward Watts; Chaitan Khosla
View on Scopus
IL-31-IL-31R interactions negatively regulate type 2 inflammation in the lung
Journal of Experimental Medicine, ISSN: 00221007 00221007
Jacqueline G. Perrigoue; Ji Li; Colby Zaph; Michael Goldschmidt; Phillip Scott; Frederic J. De Sauvage; Edward J. Pearce; Nico Ghilardi; David Artis
View on Scopus
Facilitating matched pairing and expression of TCR chains introduced into human T cells
Blood, ISSN: 00064971 00064971
Jürgen Kuball; Michelle L. Dossett; Matthias Wolfl; William Y. Ho; Ralf-Holger Voss; Carla Fowler; Philip D. Greenberg
View on Scopus
© 2024 Genentech, Inc. All rights reserved. This site is intended for US residents only.