Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10751 - 10800 OF 15396 RESULTS

AP-3-dependent mechanisms control the targeting of a chloride channel (ClC-3) in neuronal and non-neuronal cells
Journal of Biological Chemistry, ISSN: 00219258
Gloria Salazar; Rachal Love; Melanie L. Styers; Erica Werner; Andrew A. Peden; Sandra Rodriguez; Marla Gearing; Bruce H. Wainer; Victor Faundez
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Notch1-expressing cells are indispensable for prostatic branching morphogenesis during development and re-growth following castration and androgen replacement
Journal of Biological Chemistry, ISSN: 00219258
Xi-De Wang; Shou; Peter Wong; French; Gao
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Bevacizumab plus irinotecan, fluorouracil, and leucovorin for metastatic colorectal cancer
New England Journal of Medicine, ISSN: 00284793
Herbert Hurwitz; Louis Fehrenbacher; Novotny; Thomas Cartwright; John Hainsworth; William Heim; Jordan Berlin; Ari Baron; Susan Griffing; Holmgren; Napoleone Ferrara; Gwendolyn Fyfe; Rogers; Robert Ross; Fairooz F. Kabbinavar
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Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes
Endocrinology, ISSN: 00137227
Ling Fu; Linu M. John; Adams; Yu; Elizabeth Tomlinson; Renz; P. Mickey Williams; Robert Soriano; Corpuz; Moffat; Richard L. Vandlen; Laura C. Simmons; Foster; Jean-Philippe Stephan; Siao Ping Tsai; Stewart
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A public gene trap resource for mouse functional genomics [1]
Nature Genetics, ISSN: 10614036
William C. Skarnes; Harald Von Melchner; Wolfgang Wurst; Geoff Hicks; Alex S. Nord; Tony Cox; Stephen G. Young; Patricia Ruiz; Phil Soriano; Marc Tessier-Lavigne; Bruce R. Conklin; William L. Stanford; Janet Rossant
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Acute metabolic acidosis: Characterization and diagnosis of the disorder and the plasma potassium response
Journal of the American Society of Nephrology, ISSN: 10466673
Jean-Martin Wiederseiner; Juergen Muser; Thomas Lutz; Henry N. Hulter; Reto Krapf
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Oxidative and osmotic stress signaling in tumor cells is mediated by ADAM proteases and heparin-binding epidermal growth factor
Molecular and Cellular Biology, ISSN: 02707306
Oliver M. Fischer; Stefan Hart; Andreas Gschwind; Norbert Prenzel; Axel Ullrich
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Creation and characterization of a mouse model of mandibular distraction osteogenesis
Bone, ISSN: 87563282
Tony D. Fang; Randall P. Nacamuli; Hanjoon M. Song; Kenton D. Fong; Stephen M. Warren; Ali Salim; Richard A. D. Carano; Ellen H. Filvaroff; Michael T. Longaker
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Novel role for netrins in regulating epithelial behavior during lung branching morphogenesis
Current Biology, ISSN: 09609822
Yuru Liu; Elke Stein; Timothy Oliver; Yong Li; William J. Brunken; Manuel Koch; Marc Tessier-Lavigne; Brigid L.M. Hogan
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Pharmacy benefits and the use of drugs by the chronically ill
JAMA - Journal of the American Medical Association, ISSN: 00987484
Dana P. Goldman; Geoffrey F. Joyce; Jose J. Escarce; Jennifer E. Pace; Matthew D. Solomon; Marianne Laouri; Pamela B. Landsman; Steven M. Teutsch
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Identification of Wnt responsive genes using a murine mammary epithelial cell line model system
BMC Developmental Biology, ISSN: 1471213X
Lisa A. Taneyhill; Diane Pennica
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Thyrotropin-Releasing Hormone Is Induced in the Left Ventricle of Rats with Heart Failure and Can Provide Inotropic Support to the Failing Heart
Circulation, ISSN: 00097322
Hongkui Jin; Grazyna Fedorowicz; Renhui Yang; Annie Ogasawara; Franklin V. Peale Jr.; Thinh Q. Pham; Nicholas F. Paoni
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The Dorsolateral Corticospinal Tract in Mice: An Alternative Route for Corticospinal Input to Caudal Segments following Dorsal Column Lesions
Journal of Comparative Neurology, ISSN: 00219967
Oswald Steward; Binhai Zheng; Carole Ho; Kim Anderson; Marc Tessier-Lavigne
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The ubiquitin ligase COP1 is a critical negative regulator of p53
Nature, ISSN: 00280836
David Dornan; Ingrid E. Wertz; Harumi Shimizu; David Arnott; Gretchen D. Frantz; Patrick Dowd; Karen M. O'Rourke; Koeppen; Vishva M. Dixit
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Crystal structure of Clostridium botulinum neurotoxin protease in a product-bound state: Evidence for noncanonical zinc protease activity
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Brent Segelke; Mark Knapp; Saloumeh Kadkhodayan; Rod Balhorn; Bernhard Rupp
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N-Benzoyl amino acids as ICAM/LFA-1 inhibitors. Part 2: Structure-activity relationship of the benzoyl moiety
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Burdick; James C. Marsters Jr.; Ignacio Aliagas; Mark S. Stanley; Beresini; Clark; Robert S. McDowell; Thomas Gadek
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Expression of Toll-Like Receptor 2 on CD16+ Blood Monocytes and Synovial Tissue Macrophages in Rheumatoid Arthritis
Arthritis and Rheumatism, ISSN: 00043591
Mitsuhiro Iwahashi; Masahiro Yamamura; Tetsushi Aita; Akira Okamoto; Akiko Ueno; Norio Ogawa; Sachiko Akashi; Kensuke Miyake; Godowski; Hirofumi Makino
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Phage-display as a tool for quantifying protein stability determinants
European Journal of Biochemistry, ISSN: 00142956
Joanne D. Kotz; Christopher J. Bond; Andrea G Cochran
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Growth Hormone (GH) Replacement Therapy in Adult-Onset GH Deficiency: Effects on Body Composition in Men and Women in a Double-Blind, Randomized, Placebo-Controlled Trial
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Andrew R. Hoffman; Joyce Kuntze; Joyce Baptista; Howard B. A. Baum; Gerhard Baumann; Beverly M. K. Biller; Richard V. Clark; David Cook; Silvio E. Inzucchi; David Kleinberg; Anne Klibanski; Lawrence S. Phillips; E. Chester Ridgway; Richard J. Robbins; Janet Schlechte; Meeta Sharma; Michael O. Thorner; Mary Lee Vance
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Rab14 Is Involved in Membrane Trafficking between the Golgi Complex and Endosomes
Molecular Biology of the Cell, ISSN: 10591524
Jagath R. Junutula; Ann De Mazière; Andrew A. Peden; Karen E. Ervin; Raj J. Advani; Suzanne Van Dijk; Judith Klumperman; Richard H. Scheller
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Pharmacokinetics of the antimalarial drug, AQ-13, in rats and cynomolgus macaques
International Journal of Toxicology, ISSN: 10915818 1092874X
Sandhya Ramanathan-Girish; Paul Catz; Moire R. Creek; Benjamin Wu; David Thomas; Donald J. Krogstad; Dibyendu De; Jon C. Mirsalis; Carol E. Green
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Expression of vascular endothelial growth factor, hypoxia inducible factor 1α, and carbonic anhydrase IX in human tumours
Journal of Clinical Pathology, ISSN: 00219746
Adrian M. Jubb; Thinh Q. Pham; Hanby; Gretchen D. Frantz; Franklin V. Peale Jr.; Thomas D Wu; Koeppen; Kenneth J. Hillan
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SLIT2-Mediated ROBO2 signaling restricts kidney induction to a single site
Developmental Cell, ISSN: 15345807
Uta Grieshammer; Le Ma; Andrew Plump; Fan Wang; Marc Tessier-Lavigne; Gail R. Martin
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Latent Membrane Protein 2A, a Viral B Cell Receptor Homologue, Induces CD5+ B-1 Cell Development
Journal of Immunology, ISSN: 00221767
Akiko Ikeda; Mark Merchant; Lori Lev; Richard Longnecker; Masato Ikeda
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Structure of the neural (N-) cadherin prodomain reveals a cadherin extracellular domain-like fold without adhesive characteristics
Structure, ISSN: 09692126
Alexander W. Koch; Amjad Farooq; Shan; Lei Zeng; David R. Colman; Ming-Ming Zhou
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Pathogenic roles of B cells in human autoimmunity: Insights from the clinic
Immunity, ISSN: 10747613
Flavius Martin; Andrew A. Chan
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Pulmonary Exacerbations in Cystic Fibrosis
Pediatric Pulmonology, ISSN: 87556863
Harvey R. Rabin; Butler; Mary Ellen Wohl; David E. Geller; Andrew A. Colin; Daniel V. Schidlow; Charles A. Johnson; Michael W. Konstan; Warren E. Regelmann
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Effects of simultaneous over-expression of Cu/ZnSOD and MnSOD on Drosophila melanogaster life span
Mechanisms of Ageing and Development, ISSN: 00476374
Jingtao Sun; John Molitor; John Tower
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Absenteeism among employees with irritable bowel syndrome
Managed Care Interface, ISSN: 10965645
Christopher Zacker; Chawla; Shaohung Wang; Leigh Ann Albers
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In the age of the biologics, is phototherapy obsolete?
Cosmetic Dermatology, ISSN: 10413766
John Y. Koo
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IL-22, a Th1 cytokine that targets the pancreas and select other peripheral tissues
International Immunopharmacology, ISSN: 15675769
Austin L. Gurney
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VEGFA is necessary for chondrocyte survival during bone development
Development (Cambridge), ISSN: 09501991
Elazar Zelzer; Roni Mamluk; Napoleone Ferrara; Randall S. Johnson; Ernestina Schipani; Bjorn R. Olsen
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NTB-A, a New Activating Receptor in T Cells That Regulates Autoimmune Disease
Journal of Biological Chemistry, ISSN: 00219258
Patricia A. Valdez; Hua Wang; Dhaya Seshasayee; Menno Van Lookeren Campagne; Austin L. Gurney; Wyne P. Lee; Iqbal S. Grewal
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Rescue of NGF-deficient mice II: Basal forebrain cholinergic projections require NGF for target innervation but not guidance
Molecular Brain Research, ISSN: 0169328X
Phillips; Merry Nishimura; Armanini; Grace Chan; Albers; Davis
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Phage-displayed antibody libraries of synthetic heavy chain complementarity determining regions
Journal of Molecular Biology, ISSN: 00222836
Sachdev S. Sidhu; Bing Li; Chen; Frederic A. Fellouse; Eigenbrot; Fuh
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Engineering an APRIL-specific B Cell Maturation Antigen
Journal of Biological Chemistry, ISSN: 00219258
Darshana Patel; Heidi J. A. Wallweber; Jianping Yin; Stephanie K. Shriver; Scot A. Marsters; Nathaniel C. Gordon; Melissa A. Starovasnik; Robert F. Kelley
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MALT1/Paracaspase Is a Signaling Component Downstream of CARMA1 and Mediates T Cell Receptor-induced NF-κB Activation
Journal of Biological Chemistry, ISSN: 00219258
Tuanjie Che; Yun You; Donghai Wang; Matthew J. Tanner; Vishva M. Dixit; Xin Lin
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The endothelial-cell-derived secreted factor Egfl7 regulates vascular tube formation
Nature, ISSN: 00280836
Leon Parker; Maike Schmidt; Suk-Won Jin; Gray; Dimitris Beis; Thinh Q. Pham; Gretchen D. Frantz; Susan Palmieri; Kenneth J. Hillan; Didier Y. R. Stainier; Frederic J. De Sauvage; Weilan Ye
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Neoplastic Complications of HIV Infection
AIDS and Other Manifestations of HIV Infection,
Paula O'Connor; David T. Scadden
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Trastuzumab in combination with cisplatin and gemcitabine in patients with Her2-overexpressing, untreated, advanced non-small cell lung cancer: Report of a phase II trial and findings regarding optimal identification of patients with Her2-overexpressing disease
Lung Cancer, ISSN: 01695002
Ralph G. Zinner; Bonnie S. Glisson; Frank V. Fossella; Katherine M.W. Pisters; Merril S. Kies; Pamela M. Lee; Erminia Massarelli; Bradley Sabloff; Herbert A. Fritsche Jr.; Jae Y. Ro; Nelson G. Ordonez; Hai T. Tran; Ying Yang; Terry L. Smith; Robert Mass; Roy S. Herbst
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HER2-Targeted Therapy Reduces Incidence and Progression of Midlife Mammary Tumors in Female Murine Mammary Tumor Virus huHER2-Transgenic Mice
Clinical Cancer Research, ISSN: 10780432
David Finkle; Zhi Ricky Quan; Vida Asghari; Jessica Kloss; Nazli Ghaboosi; Elaine Mai; Wai Lee T. Wong; Hollingshead; Ralph H. Schwall; Koeppen; Sharon Erickson
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Blockade of Epidermal Growth Factor- or Heregulin-Dependent ErbB2 Activation with the Anti-ErbB2 Monoclonal Antibody 2C4 Has Divergent Downstream Signaling and Growth Effects
Cancer Research, ISSN: 00085472
James G. Jackson; Patricia St. Clair; Mark X. Sliwkowski; Michael G. Brattain
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Syntaxin-6 SNARE Involvement in Secretory and Endocytic Pathways of Cultured Pancreatic β-Cells
Molecular Biology of the Cell, ISSN: 10591524
Regina Kuliawat; Elena Kalinina; Jason Bock; Lloyd Fricker; Timothy E. McGraw; Se Ryoung Kim; Jiayu Zhong; Richard H. Scheller; Peter Arvan
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Rescue of NGF-deficient mice I: Transgenic expression of NGF in skin rescues mice lacking endogenous NGF
Molecular Brain Research, ISSN: 0169328X
Susan M.W. Harrison; Davis; Merry Nishimura; Albers; Marc E. Jones; Phillips
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Localization of the AP-3 adaptor complex defines a novel endosomal exit site for lysosomal membrane proteins
Journal of Cell Biology, ISSN: 00219525
Andrew A. Peden; Viola Oorschot; Boris A. Hesser; Cary D. Austin; Richard H. Scheller; Judith Klumperman
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Expansion of Protein Interaction Maps by Phage Peptide Display Using MDM2 as a Prototypical Conformationally Flexible Target Protein
Journal of Molecular Biology, ISSN: 00222836
Lindsay Burch; Harumi Shimizu; Amanda Smith; Cam Patterson; Ted R. Hupp
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The Crystal Structure of Placental Growth Factor in Complex with Domain 2 of Vascular Endothelial Growth Factor Receptor-1
Journal of Biological Chemistry, ISSN: 00219258
Hans W. Christinger; Fuh; De Vos; Wiesmann
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High-Level Accumulation of a Recombinant Antibody Fragment in the Periplasm of Escherichia coli Requires a Triple-Mutant (degP prc spr) Host Strain
Biotechnology and Bioengineering, ISSN: 00063592
Christina Y. Chen; Snedecor; Julie C. Nishihara; John C. Joly; Nancy McFarland; Dana C. Andersen; John E. Battersby; Kathleen M. Champion
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Albumin Stimulates the Accumulation of Extracellular Matrix in Renal Tubular Epithelial Cells
American Journal of Nephrology, ISSN: 02508095
Jean-Philippe Stephan; Mao; Ellen H. Filvaroff; Liping Cai; Ralph Rabkin; Pan
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EG-VEGF and Bv8: A novel family of tissue-restricted angiogenic factors
Biochimica et Biophysica Acta - Reviews on Cancer, ISSN: 0304419X
Napoleone Ferrara; Jennifer Lecouter; Rui Lin; Franklin V. Peale Jr.
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