Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 10951 - 11000 OF 15396 RESULTS

Photodetachment of hydrated oxalate dianions in the gas phase, C 2O42-(H2O)n (n-3-40): From solvated clusters to nanodroplet
Journal of Chemical Physics, ISSN: 00219606
Xue-Bin Wang; Xin Yang; John B. Nicholas; Lai-Sheng Wang
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Complex with a phage display-derived peptide provides insight into the function of insulin-like growth factor I
Biochemistry, ISSN: 00062960
Schaffer; Deshayes; Nakamura; Sachdev S. Sidhu; Nicholas J. Skelton
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Dynamics of cell surface molecules during T cell recognition
Annual Review of Biochemistry, ISSN: 00664154
Mark M. Davis; Michelle Krogsgaard; Johannes B. Huppa; Cenk Sumen; Marco A. Purbhoo; Darrell J. Irvine; Lawren C. Wu; Lauren Ehrlich
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Structural insight into how an anti-idiotypic antibody against D3H44 (anti-tissue factor antibody) restores normal coagulation
Journal of Molecular Biology, ISSN: 00222836
Eigenbrot; Meng; Rajeswari Krishnamurthy; Michael T. Lipari; Presta; Devaux; Wong; Paul Moran; Sherron L. Bullens; Daniel Kirchhofer
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The forkhead transcription factor FOXO4 induces the down-regulation of hypoxia-inducible factor 1α by a von Hippel-Lindau protein-independent mechanism
Journal of Biological Chemistry, ISSN: 00219258
Tracy Tzu-Ling Tang; Lasky
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The effects of an anti-CD11a mAb, efalizumab, on allergen-induced airway responses and airway inflammation in subjects with atopic asthma
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Gauvreau; Allan B. Becker; Boulet; Jamila Chakir; Robert B. Fick Jr.; William L. Greene; Killian; O'Byrne; John K. Reid; Cockcroft
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Electron and excitation transfer in hetero-supramolecular assemblies and at molecule-nanoparticle interfaces
Pure and Applied Chemistry, ISSN: 00334545
Piotrowiak; Deshayes; Romanova; Cynthia Pagba; Sarmimala Hore; Giovanni Zordan; Ileana Place; Agnes Farrán
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Quantitative analysis of colorectal tissue microarrays by immunofluorescence and in situ hybridization
Journal of Pathology, ISSN: 00223417
Adrian M. Jubb; Landon; Jennifer Burwick; Thinh Q. Pham; Gretchen D. Frantz; Cairns; Philip Quirke; Franklin V. Peale Jr.; Kenneth J. Hillan
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Comparison of neural network, Bayesian, and multiple stepwise regression-based limited sampling models to estimate area under the curve
Pharmacotherapy, ISSN: 02770008
Chee Ng
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The hypoxic response of tumors is dependent on their microenvironment
Cancer Cell, ISSN: 15356108
Barbara Blouw; Hanqiu Song; Tarik Tihan; Jenel Bosze; Napoleone Ferrara; Hans-Peter Gerber; Randall S. Johnson; Gabriele Bergers
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Structure and function analysis of peptide antagonists of melanoma inhibitor of apoptosis (ML-IAP)
Biochemistry, ISSN: 00062960
Matthew C Franklin; Saloumeh Kadkhodayan; Heidi J. A. Wallweber; Daniela Alexandru; Mark D. Distefano; Linda O. Elliott; Flygare; Grace Mausisa; David C Okawa; Danny Ong; Domagoj Vucic; Deshayes; Wayne J. Fairbrother
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Mice lacking the CARD of CARMA1 exhibit defective B lymphocyte development and impaired proliferation of their B and T lymphocytes
Current Biology, ISSN: 09609822
Kim Newton; Vishva M. Dixit
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Trail/Apo2L
The Cytokine Handbook,
David H. Lynch; Avi Ashkenazi
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Early use of glycoprotein IIb/IIIa inhibitors in non-ST-elevation acute myocardial infarction: Observations from the national registry of myocardial infarction 4
Journal of the American College of Cardiology, ISSN: 07351097
Eric D. Peterson; Charles V. Pollack Jr.; Matthew T. Roe; Lori Parsons; Katherine A. Littrell; John G. Canto; Hal V. Barron
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Structural basis of the interaction between RalA and Sec5, a subunit of the sec6/8 complex
EMBO Journal, ISSN: 02614189
Shuya Fukai; Hugo T. Matern; Jagath R. Junutula; Richard H. Scheller; Axel T. Brünger
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Comparison of the Escherichia coli proteomes for recombinant human growth hormone producing and nonproducing fermentations
Proteomics, ISSN: 16159853
Kathleen M. Champion; Julie C. Nishihara; Ilana S. Aldor; G. Tony Moreno; Dana C. Andersen; Kathy L. Stults; Vanderlaan
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Nrf1 is critical for redox balance and survival of liver cells during development
Molecular and Cellular Biology, ISSN: 02707306
Linyun Chen; Mandy Kwong; Ronghua Lu; David G. Ginzinger; Candy Lee; Laura Leung; Jefferson Y. Chan
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Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation
Molecular and Cellular Biology, ISSN: 02707306
Vernon T. Phan; David B. Shultz; Bao-Tran Truong; Timothy J. Blake; Anna L. Brown; Thomas J. Gonda; Michelle M. Le Beau; Scott C. Kogan
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Production of the signalling molecule, autoinducer-2, by Neisseria meningitidis: Lack of evidence for a concerted transcriptional response
Microbiology, ISSN: 13500872
Joanne E. Dove; Kazutoyo Yasukawa; Colin R. Tinsley; Xavier Nassif
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Automated sample preparation using vapor-phase hydrolysis for amino acid analysis
Analytical Biochemistry, ISSN: 00032697
Alan Higbee; Susan C. Wong; William J. Henzel
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Cooperation of cytokine signaling with chimeric transcription factors in leukemogenesis: PML-retinoic acid receptor alpha blocks growth factor-mediated differentiation
Molecular and Cellular Biology, ISSN: 02707306
Vernon T. Phan; David B. Shultz; Bao-Tran Truong; Timothy J. Blake; Anna L. Brown; Thomas J. Gonda; Michelle M. Le Beau; Scott Kogan
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Neutropenia in patients treated with rituximab [6] (multiple letters)
New England Journal of Medicine, ISSN: 00284793
Eric Voog; Morschhauser; Philippe Solal-Celigny; Benyunes; Pratik S. Multani; Andrew Saunders
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Interstitial pneumonitis related to rituximab therapy [5] (multiple letters)
New England Journal of Medicine, ISSN: 00284793
Catherine Burton; Richard Kaczmarski; Riaz Jan-Mohamed; Benyunes; Pratik S. Multani; Andrew Saunders
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Bolus inhalation of rhDNAse with the AERx system in subjects with cystic fibrosis
Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung, ISSN: 08942684
David E. Geller; John Thipphawong; Babatunde Otulana; Daniel Caplan; Dawn Ericson; Laura Milgram; Jerry Okikawa; Joanne M. Quan; C. Michael Bowman
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Redesigning an antibody fragment for faster association with its antigen
Biochemistry, ISSN: 00062960
Jonathan S. Marvin; Henry B. Lowman
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Role of VEGF-A in vascularization of pancreatic islets
Current Biology, ISSN: 09609822
Eckhard Lammert; Guoqiang Gu; Margaret McLaughlin; Dennis Brown; Rolf Brekken; Lewis Charles Murtaugh; Hans-Peter Gerber; Napoleone Ferrara; Douglas A. Melton
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Discovery of small molecule leads in a biotechnology datastream
Drug Discovery Today, ISSN: 13596446
Thomas Gadek; Robert S. McDowell
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Engineering exosite peptides for complete inhibition of factor VIIa using a protease switch with substrate phage
Journal of Biological Chemistry, ISSN: 00219258
Henry R. Maun; Eigenbrot; Lazarus
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A highly selective, non-hydantoin, non-carboxylic acid inhibitor of aldose reductase with potent oral activity in diabetic rat models: 6-(5-chloro-3-methylbenzofuran-2-sulfonyl)-2-H-pyridazin-3-one
Journal of Medicinal Chemistry, ISSN: 00222623
Mylari; Sandra J. Armento; Beebe; Edward L. Conn; Coutcher; Dina; Melissa T. O'Gorman; Michael C. Linhares; William H. Martin; Oates; David A. Tess; Gregory J. Withbroe; Zembrowski
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The magnitude of hedgehog signaling activity defines skin tumor phenotype
EMBO Journal, ISSN: 02614189
Vladimir Grachtchouk; Marina Grachtchouk; Lori Lowe; Tim Johnson; Lebing Wei; Aiqin Wang; Frederic J. De Sauvage; Andrzej A. Dlugosz
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Diabetic patients and retinal proliferation: An evaluation of the role of vascular endothelial growth factor (VEGF)
Experimental and Clinical Endocrinology and Diabetes, ISSN: 09477349
Nicoletti; Nicoletti; Napoleone Ferrara; Meli; Reibaldi; Alfredo Reibaldi
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Robust generation of new hair cells in the mature mammalian inner ear by adenoviral expression of Hath1
Molecular and Cellular Neuroscience, ISSN: 10447431
Shou; Zheng; Gao
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Recombinant human thrombopoietin augments mobilization of peripheral blood progenitor cells for autologous transplantation
Biology of Blood and Marrow Transplantation, ISSN: 10838791
Charles Linker; Paolo Anderlini; Herzig; Neal Christiansen; Somlo; William Bensinger; Fay; Joseph P. Lynch; Lawrence T. Goodnough; Ashby; Benyunes; Jones Jr.; Timothy A. Yang; Langdon L. Miller; Charles Weaver
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Mouse endocrine gland-derived vascular endothelial growth factor: A distinct expression pattern from its human ortholog suggests different roles as a regulator of organ-specific angiogenesis
Endocrinology, ISSN: 00137227
Jennifer Lecouter; Rui Lin; Gretchen D. Frantz; Zemin Zhang; Kenneth J. Hillan; Napoleone Ferrara
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Strategies and methods in the identification of antagonists of protein-protein interactions
BioTechniques, ISSN: 07366205
Thomas Gadek
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The biology of VEGF and its receptors
Nature Medicine, ISSN: 10788956
Napoleone Ferrara; Hans-Peter Gerber; Jennifer Lecouter
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Differential expression of the angiogenic factor genes vascular endothelial growth factor (VEGF) and endocrine gland-derived VEGF in normal and polycystic human ovaries
American Journal of Pathology, ISSN: 00029440
Napoleone Ferrara; Gretchen D. Frantz; Jennifer Lecouter; Lisa Dillard-Telm; Thinh Q. Pham; Aparna Draksharapu; Thomas Giordano; Franklin V. Peale Jr.
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Pathogenesis of mucous cell metaplasia in a murine asthma model
American Journal of Pathology, ISSN: 00029440
J. Rachel Reader; Tepper; Edward S. Schelegle; Melinda C. Aldrich; Lei F. Putney; Juergen W. Pfeiffer; Dallas M. Hyde
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BAFF/BLyS receptor 3 comprises a minimal TNF receptor-like module that encodes a highly focused ligand-binding site
Biochemistry, ISSN: 00062960
Nathaniel C. Gordon; Borlan Pan; Sarah G. Hymowitz; Jianping Yin; Robert F. Kelley; Andrea G Cochran; Minhong Yan; Vishva M. Dixit; Wayne J. Fairbrother; Melissa A. Starovasnik
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Inhibition of epithelial ductal branching in the prostate by sonic hedgehog is indirectly mediated by stromal cells
Journal of Biological Chemistry, ISSN: 00219258
Bu-Er Wang; Shou; Ross; Koeppen; Frederic J. De Sauvage; Gao
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TACE cleavage of proamphiregulin regulates GPCR-induced proliferation and motility of cancer cells
EMBO Journal, ISSN: 02614189
Andreas Gschwind; Stefan Hart; Oliver M. Fischer; Axel Ullrich
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Phosphate ester serum albumin affinity tags greatly improve peptide half-life in vivo
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Zobel; Michael F. T. Koehler; Beresini; Lisa D. Caris; Dan Combs
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Bracketed generic inactivation of rodent retroviruses by low pH treatment for monoclonal antibodies and recombinant proteins
Biotechnology and Bioengineering, ISSN: 00063592
Kurt Brorson; Sherrie Krejci; Kitty Lee; Elizabeth Hamilton; Kathryn Stein; Yuan Xu
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Activation and regulation of Toll-like receptors 2 and 1 in human leprosy
Nature Medicine, ISSN: 10788956
Stephan R. Krutzik; Maria Teresa Ochoa; Peter A. Sieling; Satoshi Uematsu; Yolanda W. Ng; Annaliza Legaspi; Philip T. Liu; Stewart T. Cole; Godowski; Yumi Maeda; Euzenir N. Sarno; Michael V. Norgard; Patrick J. Brennan; Shizuo Akira; Thomas H. Rea; Robert L. Modlin
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Inhibition of tissue factor limits the growth of venous thrombus in the rabbit
Journal of Thrombosis and Haemostasis, ISSN: 15387933 15387836
Jacques Himber; Wohlgensinger; Roux; Lisa A. Damico; John T. Fallon; Daniel Kirchhofer; Nemerson; Markus A. Riederer
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Pharmacokinetic study of patients with follicular or mantle cell lymphoma treated with rituximab as 'in vivo purge' and consolidative immunotherapy following autologous stem cell transplantation
Annals of Oncology, ISSN: 09237534
Joy Mangel; Rena Buckstein; Imrie; Spaner; Franssen; Pavlin; Boudreau; Pennell; Dan Combs; Neil Berinstein
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Vascular endothelial growth factor (VEGF) receptor-2 signaling mediates VEGF-CΔNΔC- and VEGF-A-induced angiogenesis in vitro
Experimental Cell Research, ISSN: 00144827
Jean-Christophe Tille; Xueyan Wang; Kenneth E. Lipson; Gerald McMahon; Napoleone Ferrara; Zhu; Daniel J. Hicklin; Jonathan P. Sleeman; Ulf Eriksson; Kari Alitalo; Pepper
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Design, construction, and in vitro analyses of multivalent antibodies
Journal of Immunology, ISSN: 00221767
Kathy Miller; Meng; Jun Liu; Amy Hurst; Vanessa Hsei; Wai Lee T. Wong; Rene Ekert; David Lawrence; Steve Sherwood; Laura DeForge; Jacques Gaudreault; Gilbert-Andre Keller; Mark X. Sliwkowski; Avi Ashkenazi; Presta
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Subcutaneously administered efalizumab (anti-CD11a) improves signs and symptoms of moderate to severe plaque psoriasis
Journal of Cutaneous Medicine and Surgery, ISSN: 12034754
Alice Gottlieb; Bruce Miller; Nicholas Lowe; William Shapiro; Charles Hudson; Ross Bright; Mark Ling; Anna Magee; Calvin O. McCall; Toivo Rist; Wolfgang Dummer; Patricia Walicke; Bauer; Mark White; Marvin Garovoy
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Sharing publication-related data and materials: Responsibilities of authorship in the life sciences
Plant Physiology, ISSN: 00320889
Thomas R. Cech; Sean R. Eddy; David Eisenberg; Karen Hersey; Steven H. Holtzman; George H. Poste; Natasha V. Raikhel; Richard H. Scheller; David B. Singer; Mary C. Waltham
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