Genentech: Publications

December 2, 2002

Hippocampal LTP and memory in mouse strains: Is there evidence for a causal relationship?

Hippocampus, ISSN: 10509631

Gerlai

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December 2, 2002

BLNK: Molecular scaffolding through 'cis'-mediated organization of signaling proteins

EMBO Journal, ISSN: 02614189

Christopher Chiu; Mark Dalton; Masamichi Ishiai; Tomohiro Kurosaki; Andrew A. Chan

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December 1, 2002

Endocrine gland vacular endothelial growth factor (EG-VEGF) and the hypothesis of tissue-specific regulation of angiogenesis

Endocrine Research, ISSN: 07435800

Napoleone Ferrara; Jennifer LeCounter

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December 1, 2002

Model-based analysis of the pharmacokinetic interactions between ritonavir, nelfinavir, and saquinavir after simultaneous and staggered oral administration

Drug Metabolism and Disposition, ISSN: 00909556

Jian-Feng Lu; Terrence F. Blaschke; Charles Flexner; Susan L. Rosenkranz; Lewis B. Sheiner

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December 1, 2002

Development and validation of a semi-automated 96-well protein precipitation method for quantification of plasma samples by LC/MS/MS

Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,

Bilin Chou; Robin Robertson; Kamal Boora; John Hanson; Yang Wang; Cyrus Khojasteh-Bakht

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December 1, 2002

Proteomics via multidimensional separations: Which dimensions to use?

Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,

David Arnott; Kishiyama; Iman Mohtashemi; Wendy Shillinglaw; William J. Henzel; Stults

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December 1, 2002

Dornase alfa in young patients with cystic fibrosis [1] (multiple letters)

Journal of Pediatrics, ISSN: 00223476

Edward R. Carter; Joanne M. Quan

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December 1, 2002

pKa, MM, and QM studies of mechanisms of β-lactamases and penicillin-binding proteins: Acylation step

Journal of Computational Chemistry, ISSN: 01928651

Irina Massova; Peter A. Kollman

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December 1, 2002

Characterization and monitoring of monoclonal antibody variants in process control

Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,

Bao-Jen Shyong; Eng; Galahad Deperalta; Victor Ling

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December 1, 2002

Investigation of the solvent and counter-ion stabilization of multiply charged anions in the gas phase

Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,

Xue-Bin Wang; Xin Yang; Lai-Sheng Wang; John B. Nicholas

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December 1, 2002

Characterization of the disulfide bond pattern in β-1,4- galactosyltransferase 7 by LC/ESI-MS/MS

Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,

Corpuz; Richard L. Vandlen; Ten-Yang Yen; Bruce A. Macher

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December 1, 2002

Treatment of occluded central venous catheters with alteplase: Results in 1,064 patients

Journal of Vascular and Interventional Radiology, ISSN: 10510443

Charles P. Semba; Steven R. Deitcher; Xin Li; Laura Resnansky; Tri Tu; Edward R. McCluskey

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December 1, 2002

Pharmacokinetics and pharmacodynamics of tenecteplase in fibrinolytic therapy of acute myocardial infarction

Clinical Pharmacokinetics, ISSN: 03125963

Tanswell; Modi; Dan Combs; Danays

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December 1, 2002

A generic mass spectrometric method for the quantitation of monoclonal antibody drugs in serum

Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,

Victor Ling; Bao-Jen Shyong; Bryan Sandlund; Quarmby; Gary Tanuguchi; Jonathan McNally; Van Chen

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December 1, 2002

Rapid methods for confirmation of suspected post-translational modifications

Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,

Kathy L. O'Connell; Jianping Yin; Melissa A. Starovasnik; Ying Li; Lynne Giere; Crowley; Anita Izrael-Tomasevic; Stults

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December 1, 2002

A comparison of shotgun sequencing and 2-D electrophoresis for the identification of proteins in complex mixtures: Escherichia coli whole cell lysate

Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,

Stults; David Arnott; Kathy L. O'Connell; G. Tony Moreno; Kathleen M. Champion; Shiaw-Lin Wu; Paul Shieh; William S. Hancock

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December 1, 2002

Natural heterogeneity in the constant regions of human immunoglobulins

Proceedings 50th ASMS Conference on Mass Spectrometry and Allied Topics,

Chin; Bao-Jen Shyong; Viswanatham Katta

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November 29, 2002

Structure of the epidermal growth factor receptor kinase domain alone and in complex with a 4-anilinoquinazoline inhibitor

Journal of Biological Chemistry, ISSN: 00219258

Jennifer Stamos; Mark X. Sliwkowski; Eigenbrot

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November 27, 2002

NF-κB signaling: Many roads lead to Madrid

Cell, ISSN: 00928674

Vishva M. Dixit; Tak W. Mak

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November 12, 2002

Short constrained peptides that inhibit HIV-1 entry

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Samuel K. Sia; Peter A. Carr; Andrea G Cochran; Vladimir N. Malashkevich; Peter S. Kim

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November 5, 2002

Impact of cell culture process changes on endogenous retrovirus expression

Biotechnology and Bioengineering, ISSN: 00063592

Kurt Brorson; Christina De Wit; Elizabeth Hamilton; Mehnaz Mustafa; Patrick Swann; Robert Kiss; Ron Taticek; Gian D. Polastri; Kathryn Stein; Yuan Xu

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November 1, 2002

Premenstrual dysphoric disorder is there an economic burden of Illness?

Medical Care, ISSN: 00257079

Chawla; Ralph Swindle; Stacey Long; Sean Kennedy; Barbara Sternfeld

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November 1, 2002

Phosphorylation and regulation of β-catenin by casein kinase Iε

Journal of Biochemistry, ISSN: 0021924X

Sakanaka

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November 1, 2002

A phase II study of thalidomide in advanced metastatic renal cell carcinoma

Investigational New Drugs, ISSN: 01676997

David R. Minor; Dana Monroe; Lisa A. Damico; Meng; Uma Suryadevara; Laurence Elias

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November 1, 2002

Complexation of VEGF with bevacizumab decreases VEGF clearance in rats

Pharmaceutical Research, ISSN: 07248741

Vanessa Hsei; Geralyn G. Deguzman; Nixon; Jacques Gaudreault

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October 21, 2002

Solid–phase synthesis of dual α4β1#x03B1;4β7 integrin antagonists: Two scaffolds with overlapping pharmacophores

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

Georgette M. Castanedo; Fredrick C. Sailes; Dubree; John B. Nicholas; Lisa D. Caris; Clark; Keating; Beresini; Chiu; Sherman Fong; James C. Marsters Jr.; Jackson; Daniel P. Sutherlin

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October 21, 2002

Albumin affinity tags increase peptide half-life in vivo

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

Michael F. T. Koehler; Zobel; Beresini; Lisa D. Caris; Dan Combs; Paasch; Lazarus

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October 21, 2002

Solid–phase synthesis of dual α4β1#x03B1;4β7 integrin antagonists: Two scaffolds with overlapping pharmacophores

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

Georgette M. Castanedo; Fredrick C. Sailes; Dubree; John B. Nicholas; Lisa D. Caris; Clark; Keating; Beresini; Chiu; Fong; James C. Marsters Jr.; Jackson; Daniel P. Sutherlin

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October 15, 2002

Evaluation of HER-2/neu expression in prostatic adenocarcinoma: A request for a standardized, organ specific methodology

Cancer, ISSN: 0008543X

Katya M. Sanchez; Christopher J. Sweeney; Robert Mass; Michael O. Koch; George J. Eckert; William A. Geary; Lee Ann Baldridge; Shaobo Zhang; John N. Eble; Liang Cheng

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October 5, 2002

Distinct antigenic features of linear epitopes at the N-terminus and C-terminus of 65 kDa glutamic acid decarboxylase (GAD65): Implications for autoantigen modification during pathogenesis

Clinical and Experimental Immunology, ISSN: 00099104

Al-Bukhari; Radford; Bouras; Davenport; Trigwell; Bottazzo; Lai; Schwartz; Tighe; Todd

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October 1, 2002

Initial clinical results of tenecteplase (TNK) in catheter-directed thrombolytic therapy

Journal of Endovascular Therapy, ISSN: 15266028

Mahmood K Razavi; Humberto Wong; Stephen T. Kee; Daniel Y. Sze; Charles P. Semba; Michael D. Dake

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October 1, 2002

The pharmacokinetic and pharmacodynamic characteristics of a long-acting growth hormone (GH) preparation (Nutropin Depot) in GH-deficient adults

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X

David Cook; Beverly M. K. Biller; Mary Lee Vance; Andrew R. Hoffman; Lawrence S. Phillips; Kathleen M. Ford; Benziger; Illeperuma; Sandra L. Blethen; Kenneth M. Attie; Dao; Reimann; Fielder

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October 1, 2002

BAFF/BLyS receptor 3 binds the B cell survival factor BAFF ligand through a discrete surface loop and promotes processing of NF-κB2

Immunity, ISSN: 10747613

Nobuhiko Kayagaki; Minhong Yan; Dhaya Seshasayee; Hua Wang; Wyne P. Lee; French; Iqbal S. Grewal; Andrea G Cochran; Nathaniel C. Gordon; Jianping Yin; Melissa A. Starovasnik; Vishva M. Dixit

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October 1, 2002

Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Martin O. Bergo; Bryant Gavino; Ross; Walter K. Schmidt; Christine Hong; Lonnie V. Kendall; Andreas Mohr; Margarita Meta; Harry Genant; Yebin Jiang; Erik R. Wisner; Nicholas Van Bruggen; Richard A. D. Carano; Susan Michaelis; Stephen M. Griffey; Stephen G. Young

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October 1, 2002

VEGF and the quest for tumour angiogenesis factors

Nature Reviews Cancer, ISSN: 1474175X

Napoleone Ferrara

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October 1, 2002

Suppression of antibody production by TNF-related apoptosis-inducing ligand (TRAIL)

Cellular Immunology, ISSN: 00088749

Nobuhiko Kayagaki; Noriko Yamaguchi; Masaaki Abe; Sachiko Hirose; Toshikazu Shirai; Ko Okumura; Hideo Yagita

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October 1, 2002

Inhibition of ligand-mediated HER2 activation in androgen-independent prostate cancer

Cancer Research, ISSN: 00085472

Nerissa Mendoza; Gail L. Phillips; Johnny Silva; Ralph H. Schwall; Dineli Wickramasinghe

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September 20, 2002

Albumin binding as a general strategy for improving the pharmacokinetics of proteins

Journal of Biological Chemistry, ISSN: 00219258

Dennis; Min Zhang; Meng; Miryam Kadkhodayan; Daniel Kirchhofer; Dan Combs; Lisa A. Damico

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September 15, 2002

Dissecting the oncogenic potential of Gli2: Deletion of an NH2-terminal fragment alters skin tumor phenotype

Cancer Research, ISSN: 00085472

Hong Sheng; Sara Goich; Aiqin Wang; Marina Grachtchouk; Lori Lowe; Rong Mo; Kui Lin; Frederic J. De Sauvage; Hiroshi Sasaki; Chi-chung Hui; Andrzej A. Dlugosz

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September 11, 2002

Theoretical and experimental investigation of the effect of proton transfer on the 27AI MAS NMR line shapes of zeolite-adsorbate complexes: An independent measure of solid acid strength

Journal of the American Chemical Society, ISSN: 00027863

Justin O. Ehresmann; Wei Wang; Bruno Herreros; Donat-Pierre Luigi; Venkatraman; Weiguo Song; John B. Nicholas; James F. Haw

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September 1, 2002

Endocrine gland-derived VEGF and the emerging hypothesis of organ-specific regulation of angiogenesis

Nature Medicine, ISSN: 10788956

Jennifer Lecouter; Rui Lin; Napoleone Ferrara

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September 1, 2002

Effect of glycine on pH changes and protein stability during freeze-thawing in phosphate buffer systems

Journal of Pharmaceutical Sciences, ISSN: 00223549

Katherine A. Pikal-Cleland; Cleland; Thomas J. Anchordoquy; John F. Carpenter

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September 1, 2002

Stanniocalcin 1 alters muscle and bone structure and function in transgenic mice

Endocrinology, ISSN: 00137227

Ellen H. Filvaroff; Guillet; Constance Zlot; Bao; Gladys S. Ingle; Hope Steinmetz; Hoeffel; Bunting; Ross; Richard A. D. Carano; Powell-Braxton; Graham F. Wagner; Eckert; Mary E. Gerritsen; French

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September 1, 2002

Challenging artificial genetic systems: Thymidine analogs with 5-position sulfur functionality

Nucleic Acids Research, ISSN: 03051048

Heike A. Held; Steven A. Benner

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September 1, 2002

Proteomics in mixtures: Study results of ABRF-PRG02

Journal of Biomolecular Techniques, ISSN: 15240215 19434731

David Arnott; Mary Ann Gawinowicz; Raymond A. Grant; William Lane; Len C. Packman; Kaye D. Speicher; Kathryn Stone

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September 1, 2002

Molecular forms of NGF in human and rat neuropathic tissues: Decreased NGF precursor-like immunoreactivity in human diabetic skin

Journal of the Peripheral Nervous System, ISSN: 10859489

Yiangos Yiangou; Paul Facer; Sinicropi; Timothy J. Boucher; David L. H. Bennett; McMahon; Anand

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August 29, 2002

The relationship of intracoronary stent placement following thrombolytic therapy to tissue level perfusion

Journal of Thrombosis and Thrombolysis, ISSN: 09295305

C.Michael Gibson; Frisch; Sabina A. Murphy; Steven G. Gourlay; Raymond J. Gibbons; Kenneth W. Baran; Michel Nguyen; Sebastian T. Palmeri; Hal V. Barron

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August 27, 2002

Efficient gene transduction to cultured hepatocytes by HIV-1 derived lentiviral vector

Transplantation Proceedings, ISSN: 00411345

Ohashi; Park; Ralph H. Schwall; Kay

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August 26, 2002

Sustained delivery of human growth hormone from a novel gel system: SABER™

Biomaterials, ISSN: 01429612

Okumu; Dao; Fielder; Noel Dybdal; Brooks; Samir Sane; Cleland

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August 19, 2002