Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11201 - 11250 OF 15396 RESULTS

March 29, 2002

AKT/PKB phosphorylation of p21Cip/WAF1 enhances protein stability of p21Cip/WAF1 and promotes cell survival

Journal of Biological Chemistry, ISSN: 00219258

Ying Li; Dowbenko; Lasky

March 25, 2002

A human antibody that inhibits factor IX/IXa function potently inhibits arterial thrombosis without increasing bleeding

Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642

Refino; Surinc Er Jeet; Leo Deguzman; Bunting; Daniel Kirchhofer

March 25, 2002

Inhibitors of protein-protein interactions

Expert Opinion on Therapeutic Patents, ISSN: 13543776

Denise A. Ockey; Thomas Gadek

March 15, 2002

Identification of a novel homotypic interaction motif required for the phosphorylation of receptor-interacting protein (RIP) by RIP3

Journal of Biological Chemistry, ISSN: 00219258

Xiaoqing Sun; Jianping Yin; Melissa A. Starovasnik; Wayne J. Fairbrother; Vishva M. Dixit

March 8, 2002

Characterization of endocrine gland-derived vascular endothelial growth factor signaling in adrenal cortex capillary endothelial cells

Journal of Biological Chemistry, ISSN: 00219258

Rui Lin; Jennifer Lecouter; Joe Kowalski; Napoleone Ferrara

March 7, 2002

1H, 13C, and 15N resonance assignment of the vascular endothelial growth factor receptor-binding domain in complex with a receptor-blocking peptide [5]

Journal of Biomolecular NMR, ISSN: 09252738

Borlan Pan; Wayne J. Fairbrother

March 7, 2002

Methylbenzene chemistry on zeolite HBeta: Multiple insights into methanol-to-olefin catalysis

Journal of Physical Chemistry B, ISSN: 10895647

Alain Sassi; Mark A. Wildman; Hee Jung Ahn; Paritosh Prasad; John B. Nicholas; James F. Haw

March 5, 2002

Chemometric evaluation of on-line high-pressure liquid chromatography in mammalian cell cultures: Analysis of amino acids and glucose

Biotechnology and Bioengineering, ISSN: 00063592

Tina M. Larson; Martin Gawlitzek; Heather Evans; Urs Albers; Cacia

March 5, 2002

Expression profiling of a human cell line model of prostatic cancer reveals a direct involvement of interferon signaling in prostate tumor progression

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Shou; Robert Soriano; Simon W. Hayward; Gerald R. Cunha; P. Mickey Williams; Gao

March 1, 2002

Cardiac dysfunction in the trastuzumab clinical trials experience

Journal of Clinical Oncology, ISSN: 0732183X

Andrew Seidman; Clifford Hudis; Mary Kathryn Pierri; Steven Shak; Virginia Paton; Ashby; Maureen Murphy; Stanford J. Stewart; Deborah Keefe

March 1, 2002

Microcirculation down under

Trends in Pharmacological Sciences, ISSN: 01656147

Tailoi Chan-Ling; Mary E. Gerritsen; Caryl E Hill; Paul Kubes; Michael Perry

February 22, 2002

Activation of the Wnt pathway interferes with serum response element-driven transcription of immediate early genes

Journal of Biological Chemistry, ISSN: 00219258

David A. Tice; Soloviev; Paul G. Polakis

February 15, 2002

The core membrane fusion complex governs the probability of synaptic vesicle fusion but not transmitter release kinetics

Journal of Neuroscience, ISSN: 02706474

Finley; Sejal M. Patel; Daniel V. Madison; Richard H. Scheller

February 15, 2002

Vascular endothelial-junctional adhesion molecule (VE-JAM)/JAM 2 interacts with T, NK, and dendritic cells through JAM 3

Journal of Immunology, ISSN: 00221767

Tony W. Liang; Chiu; Austin L. Gurney; Aiko Sidle; Daniel B. Tumas; Peter Schow; Foster; Toni Klassen; Kathryn Dennis; Richard A. Demarco; Thinh Q. Pham; Gretchen D. Frantz; Sherman Fong

February 15, 2002

Bacterial toxins as tools for mucosal vaccination

Drug Discovery Today, ISSN: 13596446

Mrsny; Daugherty; Marian McKee; David FitzGerald

February 15, 2002

Vascular endothelial-junctional adhesion molecule (VE-JAM)/JAM 2 interacts with T, NK, and dendritic cells through JAM 3

Journal of Immunology, ISSN: 00221767

Tony W. Liang; Chiu; Austin L. Gurney; Aiko Sidle; Daniel B. Tumas; Peter Schow; Foster; Toni Klassen; Kathryn Dennis; Richard A. Demarco; Thinh Q. Pham; Gretchen D. Frantz; Fong

February 11, 2002

Cold elicits the simultaneous induction of fatty acid synthesis and β-oxidation in murine brown adipose tissue: Prediction from differential gene expression and confirmation in vivo

FASEB Journal, ISSN: 08926638

Xing Xian; Lewin; William F. Forrest; Adams

February 8, 2002

Generation of an LFA-1 antagonist by the transfer of the ICAM-1 immunoregulatory epitope to a small molecule

Science, ISSN: 00368075

Thomas Gadek; Burdick; Robert S. McDowell; Mark S. Stanley; James C. Marsters Jr.; Kenneth J. Paris; David A. Oare; Mark E. Reynolds; Ladner; Kimberly Zioncheck; Wyne P. Lee; Gribling; Dennis; Nicholas J. Skelton; Daniel B. Tumas; Clark; Keating; Beresini; Tilley; Presta; Bodary

February 5, 2002

Stable "zeta" peptides that act as potent antagonists of the high-affinity IgE receptor

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Nakamura; Mark E. Reynolds; Chen; Melissa A. Starovasnik; Henry B. Lowman

February 5, 2002

Surface-tension-confined microfluidics

Langmuir, ISSN: 07437463

Philippe Lam; Kenneth J. Wynne; Gary E. Wnek

February 5, 2002

Nitrogen assimilation and growth of wheat under elevated carbon dioxide

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Arnold J. Bloom; David R. Smart; Duy T. Nguyen; Peter S. Searles

February 2, 2002

Host defense functions of proteolytically processed and parent (unprocessed) cathelicidins of rabbit granulocytes

Infection and Immunity, ISSN: 00199567

Kol A. Zarember; Seth S. Katz; Brian F. Tack; Laurence Doukhan; Weiss; Elsbach

January 25, 2002

PSTPIP is a substrate of PTP-PEST and serves as a scaffold guiding PTP-PEST toward a specific dephosphorylation of WASP

Journal of Biological Chemistry, ISSN: 00219258

Jean-François Côté; Ping Lin Chung; Jean-François Théberge; Maxime Hallé; Spencer; Lasky; Michel L. Tremblay

January 24, 2002

IL-17: Prototype member of an emerging cytokine family

Journal of Leukocyte Biology, ISSN: 07415400

Aggarwal; Austin L. Gurney

January 19, 2002

New insight into how tissue factor allosterically regulates Factor VIIa

Trends in Cardiovascular Medicine, ISSN: 10501738

Eigenbrot; Daniel Kirchhofer

January 15, 2002

Tissue expression of human Toll-like receptors and differential regulation of Toll-like receptor mRNAs in leukocytes in response to microbes, their products, and cytokines

Journal of Immunology, ISSN: 00221767

Kol A. Zarember; Godowski

January 8, 2002

Photodetachment and theoretical study of free and water-solvated nitrate anions, NO3-(H2O)n (n=0-6)

Journal of Chemical Physics, ISSN: 00219606

Xue-Bin Wang; Xin Yang; Lai-Sheng Wang; John B. Nicholas

January 1, 2002

The role of EG-VEGF in the regulation of angiogenesis in endocrine glands

Cold Spring Harbor Symposia on Quantitative Biology, ISSN: 00917451

Jennifer Lecouter; Rui Lin; Napoleone Ferrara

January 1, 2002

The use of an animal immunogenicity model in the development of Protropin somatrem (methionyl human growth hormone).

Developments in Biologicals, ISSN: 14246074

Andrew J.S. Jones

January 1, 2002

Analysis of Smoothened as a candidate gene for human holoprosencephaly

Gene Function and Disease, ISSN: 14387506

Jeffrey E. Ming; Bennie Jeng; Frederic J. De Sauvage; Maximilian Muenke

January 1, 2002

Quantifying β-sheet stability by phage display

Journal of Molecular Biology, ISSN: 00222836

Mark D. Distefano; Zhong; Andrea G Cochran

January 1, 2002

Role of vascular endothelial growth factor in physiologic and pathologic angiogenesis: therapeutic implications.

Seminars in Oncology, ISSN: 00937754

Napoleone Ferrara

January 1, 2002

The product development continuum: the evolution and application of the concept of comparability.

Developments in Biologicals, ISSN: 14246074

Robert L. Garnick

January 1, 2002

Detection of minute virus of mice using real time quantitative PCR in assessment of virus clearance during the purification of mammalian cell substrate derived biotherapeutics

Biologicals, ISSN: 10451056

Dejin Zhan; Margaret Roy; Christine Valera; Jesse Cardenas; Vennari; Janice W. Chen; Shengjiang Liu

January 1, 2002

Challenges with current technology for the detection, measurement and characterization of antibodies against biological therapeutics.

Developments in Biologicals, ISSN: 14246074

Mire-Sluis

January 1, 2002

Regulation of Apo2L/tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in thyroid carcinoma cells

American Journal of Pathology, ISSN: 00029440

Vassiliki Poulaki; Constantine S. Mitsiades; Vassiliki Kotoula; Sophia Tseleni-Balafouta; Avi Ashkenazi; Demetrios A. Koutras; Nicholas Mitsiades

January 1, 2002

From characterization of antibodies to prediction of immunogenicity.

Developments in Biologicals, ISSN: 14246074

Koren

January 1, 2002

In vivo regulation of plasminogen function by plasma carboxypeptidase B

Journal of Clinical Investigation, ISSN: 00219738

Carmen M. Swaisgood; Schmitt; Dan L. Eaton; Edward F. Plow

January 1, 2002

A minimized M13 coat protein defines the requirements for assembly into the bacteriophage particle

Journal of Molecular Biology, ISSN: 00222836

Tomer A. Roth; Gregory A. Weiss; Eigenbrot; Sachdev S. Sidhu

January 1, 2002

Sequence plasticity in the antigen-binding site of a therapeutic anti-Her2 antibody

Journal of Molecular Biology, ISSN: 00222836

Gerstner; Paul J. Carter; Henry B. Lowman

January 1, 2002

MAGI-1: A widely expressed, alternatively spliced tight junction protein

Experimental Cell Research, ISSN: 00144827

Richard Laura; Ross; Koeppen; Lasky

January 1, 2002

Cardiotrophin-1 and urocortin cause protection by the same pathway and hypertrophy via distinct pathways in cardiac myocytes

Cytokine, ISSN: 10434666

Julia Railson; Zhihong Liao; Bhawanjit K. Brar; Joanna C. Buddle; Diane Pennica; Anastatis Stephanou; David S. Latchman

January 1, 2002

Development of a frozen cell array as a high-throughput approach for cell-based analysis

American Journal of Pathology, ISSN: 00029440

Jean-Philippe Stephan; Silvia Schanz; Anne Wong; Peter Schow; Wai Lee T. Wong

January 1, 2002

Inhospital outcome of acute myocardial infarction in patients with prior coronary artery bypass surgery

American Heart Journal, ISSN: 00028703

Verghese Mathew; Bernard Gersh; Hal V. Barron; Nathan R. Every; Alan J. Tiefenbrunn; Paul D. Frederick; Judith A. Malmgren

January 1, 2002

A slow release formulation of insulin as a treatment for osteoarthritis

Osteoarthritis and Cartilage, ISSN: 10634584

Liping Cai; Okumu; Cleland; Beresini; Deborah A. Hogue; Lin; Ellen H. Filvaroff

January 1, 2002

Measuring patients' trust in their primary care providers

Medical Care Research and Review, ISSN: 10775587

Mark A. Hall; Zheng; Elizabeth Dugan; Fabian Camacho; Kristin E. Kidd; Aneil Mishra; Rajesh Balkrishnan

January 1, 2002

Can a small-molecular gadolinium contrast agent be applied successfully with dynamic MRI to quantitatively define brain tumor microvascular responses to angiogenesis inhibition?

Academic Radiology, ISSN: 10766332

Robert C. Brasch; Axel Gossmann; Thomas H. Helbich; Nagato Kuriyama; Timothy P.L. Roberts; David M. Shames; Nicholas Van Bruggen; Michael F. Wendland; Mark A. Israel

January 1, 2002

Effects of early treatment with growth hormone on infarct size, survival, and cardiac gene expression after acute myocardial infarction

Growth Hormone and IGF Research, ISSN: 10966374

Hongkui Jin; Renhui Yang; Hsienwie Lu; Annie Ogasawara; Wei Li; Anne Ryan; Franklin V. Peale Jr.; Nicholas F. Paoni

January 1, 2002

Epigenetic changes in tumor Fas levels determine immune escape and response to therapy

Cancer Cell, ISSN: 15356108

Heather Maecker; Zhong Yun; Holden T. Maecker; Amato J. Giaccia

January 1, 2002

Expression of transgene encoded TGF-β in islets prevents autoimmune diabetes in NOD mice by a local mechanism

Journal of Autoimmunity, ISSN: 08968411

Iqbal S. Grewal; Kate D. Grewal; F. Susan Wong; Hua Wang; Dominic E. Picarella; Charles A. Janeway Jr.; Richard A. Flavell

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