Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11401 - 11450 OF 15396 RESULTS

Surface properties, fibrinogen adsorption, and cellular interactions of a novel phosphorylcholine-containing self-assembled monolayer on gold
Langmuir, ISSN: 07437463
Vassiliki A. Tegoulia; Weisun Rao; Anand T. Kalambur; John F. Rabolt; Stuart L. Cooper
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Solvent migration in a paraffin deposit
Fuel, ISSN: 00162361
Cordoba; Schall
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Application of a heat transfer method to determine wax deposition in a hydrocarbon binary mixture
Fuel, ISSN: 00162361
Cordoba; Schall
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Regulation of the Caenorhabditis elegans longevity protein DAF-16 by insulin/IGF-1 and germline signaling
Nature Genetics, ISSN: 10614036
Kui Lin; Honor Hsin; Natasha Libina; Cynthia Kenyon
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Partial molar volume, surface area, and hydration changes for equilibrium unfolding and formation of aggregation transition state: High-pressure and cosolute studies on recombinant human IFN-γ
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Jonathan N. Webb; Serena D. Webb; Cleland; John F. Carpenter; Theodore W. Randolph
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Recognition of 16S rRNA by ribosomal protein S4 from Bacillus stearothermophilus
Biochemistry, ISSN: 00062960
Gerstner; Pak; Draper
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PTEN 2, a Golgi-associated Testis-specific Homologue of the PTEN Tumor Suppressor Lipid Phosphatase
Journal of Biological Chemistry, ISSN: 00219258
Yan Wu; Dowbenko; Pisabarro; Lisa Dillard-Telm; Koeppen; Lasky
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Effects of cardiotrophin-1 (CT-1) in a mouse motor neuron disease
Muscle and Nerve, ISSN: 0148639X
Hiroshi Mitsumoto; Bogdan Klinkosz; Erik P. Pioro; Kazufumi Tsuzaka; Takeo Ishiyama; O'Leary; Diane Pennica
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Early initiation of growth hormone treatment allows age-appropriate estrogen use in Turner's syndrome
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Edward O. Reiter; Sandra L. Blethen; Joyce Baptista; Lisa Price
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More than one way to skin a catenin
Cell, ISSN: 00928674
Paul G. Polakis
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A naturally occurring secreted human ErbB3 receptor isoform inhibits heregulin-stimulated activation of ErbB2, ErbB3, and ErbB4
Cancer Research, ISSN: 00085472
Hakjoo Lee; Robert W. Akita; Mark X. Sliwkowski; Nita J. Maihle
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Stimulus properties of 7-OH-DPAT versus auto- and postsynaptic receptor-specific doses of quinpirole
Pharmacology Biochemistry and Behavior, ISSN: 00913057
Christina L. Zuch; Deborah A. Cory-Slechta
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A persistent carbenium ion on the methanol-to-olefin catalyst HSAPO-34: Acetone shows the way
Journal of Physical Chemistry B, ISSN: 10895647
Weiguo Song; John B. Nicholas; James F. Haw
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Lysophosphatidic acid induction of vascular endothelial growth factor expression in human ovarian cancer cells
Journal of the National Cancer Institute, ISSN: 00278874
Yu-Long Hu; Meng-Kian Tee; Edward J. Goetzl; Nelly Auersperg; Gordon B. Mills; Napoleone Ferrara; Robert B. Jaffe
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Overexpression of the retinoic acid-responsive gene Stra6 in human cancers and its synergistic induction by Wnt-1 and retinoic acid
Cancer Research, ISSN: 00085472
Szeto; Wen Jiang; David A. Tice; Bonnee Rubinfeld; Hollingshead; Fong; Dugger; Thinh Q. Pham; Yansura; Wong; J. Christopher Grimaldi; Corpuz; Singh; Gretchen D. Frantz; Devaux; Crowley; Ralph H. Schwall; Eberhard; Rastelli; Paul G. Polakis; Diane Pennica
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Development of poly-(D,L-lactide-coglycolide) microsphere formulations containing recombinant human vascular endothelial growth factor to promote local angiogenesis
Journal of Controlled Release, ISSN: 01683659
Cleland; Duenas; Ann Park; Daugherty; Jeanne Kahn; Joe Kowalski; R. Andrew Cuthbertson
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Tryptophan zippers: Stable, monomeric β-hairpins
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Andrea G Cochran; Nicholas J. Skelton; Melissa A. Starovasnik
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A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Frank J. Giordano; Hans-Peter Gerber; Simon P. Williams; Nicholas Vanbruggen; Bunting; Pilar Ruiz-Lozano; Yusu Gu; Anjali K. Nath; Yan Huang; Reed Hickey; Nancy Dalton; Kirk L. Peterson; John Ross Jr.; Kenneth R. Chien; Napoleone Ferrara
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Therapy for 6.5-7.5 years with recombinant insulin-like growth factor I in children with growth hormone insensitivity syndrome: A clinical research center study
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Philippe F. Backeljauw; Louis E. Underwood; Miras; Arriazu; Heinrich; Ghizzoni; Sandra L. Blethen; Donaldson; Cleveland; Duncan
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fucosyltransferase1 and H-type complex carbohydrates modulate epithelial cell proliferation during prostatic branching morphogenesis
Developmental Biology, ISSN: 00121606
Paul C. Marker; Jean-Philippe Stephan; James Lee; Bald; Mather; Gerald R. Cunha
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CrkL is an adapter for Wiskott-Aldrich syndrome protein and Syk
Blood, ISSN: 00064971
Atsushi Oda; Hans D. Ochs; Lasky; Spencer; Katsutoshi Ozaki; Mitsuhiro Fujihara; Makoto Handa; Kenji Ikebuchi; Hisami Ikeda
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Chinese hamster ovary (CHO) cells may express six β 4-galactosyltransferases (β4GalTs). Consequences of the loss of functional β4Galt-1, β4GalT-6, or both in CHO glycosylation mutants
Journal of Biological Chemistry, ISSN: 00219258
JaeHoon Lee; Subha Sundaram; Nancy L. Shaper; T. Shantha Raju; Pamela Stanley
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Standard errors for the cox proportional hazards cure model
Mathematical and Computer Modelling, ISSN: 08957177
Sy; Jeremy M.G. Taylor
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Differential hepatocyte toxicity of recombinant Apo2L/TRAIL versions [2]
Nature Medicine, ISSN: 10788956
David Lawrence; Shahrokh; Scot A. Marsters; Kirsten Achilles Poon; Danny Shih; Barbara Mounho; Kenneth J. Hillan; Klara Totpal; Laura DeForge; Peter Schow; Jeff Hooley; Steve Sherwood; Roger Pai; Susan Leung; Lolo Khan; Brian Gliniak; Bussiere; Craig A. Smith; Stephen S. Strom; Kelley; Judy Fox; Deborah Thomas; Avi Ashkenazi
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Isotype-dependent inhibition of tumor growth in vivo by monoclonal antibodies to death receptor 4
Journal of Immunology, ISSN: 00221767
Anan Chuntharapai; Dodge; Grimmer; Kurt A. Schroeder; Scot A. Marsters; Koeppen; Avi Ashkenazi; K.Jin Kim
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Rapid method for monitoring galactosylation levels during recombinant antibody production by electrospray mass spectrometry with selective-ion monitoring
Journal of Chromatography A, ISSN: 00219673
Hong Z. Wan; Stacey Kaneshiro; John Frenz; Cacia
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Capillary electrophoresis in the development of recombinant protein biopharmaceuticals
Chromatographia, ISSN: 00095893
Chen; Eleanor Canova-Davis; Anthony B. Chen; Wassim Nashabeh; Timothy Wehr
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Effects of the solution environment on the resolution of recombinant human deoxyribonuclease variants in capillary zone electrophoresis
Chromatographia, ISSN: 00095893
Quan; Eleanor Canova-Davis; Chen; Anthony B. Chen; Wassim Nashabeh; Timothy Wehr
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Capillary electrophoresis in the development of recombinant protein biopharmaceuticals
Chromatographia, ISSN: 00095893
Eleanor Canova-Davis; Chen; Wassim Nashabeh; Timothy Wehr
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Effects of the solution environment on the resolution of recombinant human deoxyribonuclease variants in capillary zone electrophoresis
Chromatographia, ISSN: 00095893
Quan; Eleanor Canova-Davis; Chen; Wassim Nashabeh; Timothy Wehr
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cMet activation allows persistent engraftment of ectopically transplanted xenogenic human hepatocytes in mice
Transplantation Proceedings, ISSN: 00411345
Ohashi; Meuse; Ralph H. Schwall; Kay
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Emerging protein delivery methods
Current Opinion in Biotechnology, ISSN: 09581669
Cleland; Daugherty; Mrsny
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Membrane separations in biotechnology
Current Opinion in Biotechnology, ISSN: 09581669
Robert Van Reis; Andrew Zydney
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Crystallographic and solution studies of an activation loop mutant of the insulin receptor tyrosine kinase: Insights into kinase mechanism
Journal of Biological Chemistry, ISSN: 00219258
Jeffrey H. Till; Ararat J. Ablooglu; Mark Frankel; Steven M. Bishop; Ronald A. Kohanski; Stevan R. Hubbard
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The structure and activity of a monomeric interferon-γ:α-chain receptor signaling complex
Structure, ISSN: 09692126
Michael Randal; Anthony A. Kossiakoff
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Transplantation of a fetus with paternal Thy-1+ CD34+ cells for chronic granulomatous disease
Bone Marrow Transplantation, ISSN: 02683369
Muench; Julie Rae; Bárcena; Leemhuis; Farrell; Humeau; Maxwell-Wiggins; Capper; Mychaliska; Albanese; Martin; Tsukamoto; John T. Curnutte; Harrison
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Overexpression of HER2/neu in solid tumours: An immunohistochemical survey
Histopathology, ISSN: 03090167
Koeppen; Wright; Burt; Philip Quirke; McNicol; Noel Dybdal; Mark X. Sliwkowski; Kenneth J. Hillan
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Use of chemotherapy plus a monoclonal antibody against her2 for metastatic breast cancer that overexpresses HER2
New England Journal of Medicine, ISSN: 00284793
Dennis J. Slamon; Brian R. Leyland-Jones; Steven Shak; Henry J. Fuchs; Virginia Paton; Alex Bajamonde; Thomas R. Fleming; Wolfgang Eiermann; Janet Wolter; Pegram; Baselga; Norton
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Recombinant human thrombopoietin (rhTPO) after autologous bone marrow transplantation: A phase I pharmacokinetic and pharmacodynamic study
Bone Marrow Transplantation, ISSN: 02683369
Wolff; Herzig; Joseph P. Lynch; Ericson; Greer; Stein; Goodman; Benyunes; Ashby; Jones Jr.; Fay
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Identification of multiple sources of charge heterogeneity in a recombinant antibody
Journal of Chromatography B: Biomedical Sciences and Applications, ISSN: 13872273
Reed J. Harris; Bruce Kabakoff; Frank D. Macchi; Felicity J. Shen; Kwong; Andya; Steven J. Shire; Nancy Bjork; Klara Totpal; Chen
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High Resolution Mapping of the Binding Site on Human IgG1 for FcγRI, FcγRII, FcγRIII, and FcRn and Design of IgG1 Variants with Improved Binding to the FcγR
Journal of Biological Chemistry, ISSN: 00219258
Robert L. Shields; Angela K. Namenuk; Kyu Hong; Meng; Julie Rae; Briggs; Dong Xie; Lai; Andrew Stadlen; Betty Li; Judy Fox; Presta
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Death or nonfatal stroke in patients with acute myocardial infarction treated with tissue plasminogen activator
American Journal of Cardiology, ISSN: 00029149
Brad G. Angeja; Amy Chen Rundle; Jerry H. Gurwitz; Joel M. Gore; Hal V. Barron
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One product, one process, one set of specifications: A proven quality paradigm for the safety and efficacy of biologic drugs
Pharmaceutical Technology North America, ISSN: 15342131
Copmann; Gregory Davis; Robert L. Garnick; John Landis; Lubiniecki; Tobias Massa; Gene Murano; Kenneth Seamon; Diane Zezza
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Effect of selective or combined inhibition of integrins αIIbβ3 and αvβ3 thrombosis and neointima after oversized porcine coronary angioplasty
Circulation, ISSN: 00097322
Chico; Janet Chamberlain; Gunn; Arnold; Sherron L. Bullens; Thomas Gadek; Sheila E. Francis; Bunting; Horton; Lynda Shepherd; Michael T. Lipari; Quan; Knolle; Stilz; Peyman; Crossman
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Efficacy of intracoronary or intravenous VEGF165 in a pig model of chronic myocardial ischemia
Journal of the American College of Cardiology, ISSN: 07351097
Kaori Sato; Tiangen Wu; Roger J Laham; Robert B Johnson; Pamela Douglas; Jianyi Li; Frank W Sellke; Bunting; Michael Simons; Mark J Post
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Vascular Endothelial Growth Factor KDR Receptor Signaling Potentiates Tumor Necrosis Factor-induced Tissue Factor Expression in Endothelial Cells
Journal of Biological Chemistry, ISSN: 00219258
Shen; David Y. Lee; Karen M. Cortopassi; Lisa A. Damico; Zioncheck
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Cardiotrophin-1, a muscle-derived cytokine, is required for the survival of subpopulations of developing motoneurons
Journal of Neuroscience, ISSN: 02706474
Ronald W. Oppenheim; Stefan Wiese; David Prevette; Armanini; Siwei Wang; Lucien J. Houenou; Bettina Holtmann; Rudolf Götz; Diane Pennica; Michael Sendtner
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Vascular endothelial growth factor-mediated endothelium- dependent relaxation is blunted in spontaneously hypertensive rats
Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565
Ming-Hui Liu; Hongkui Jin; H. Storm Floten; Qin Yang; Anthony P. C. Yim; Anthony Furnary; Zioncheck; Bunting; Guo-Wei He
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Elimination pathways of [14C]losoxantrone in four cancer patients
Drug Metabolism and Disposition, ISSN: 00909556
Amita Joshi; Pieniaszek H.J.; Vokes; Nicholas J. Vogelzang; Davidson; Richards; Chai; Finizio; Ratain
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Effects of early angiotensin-converting enzyme inhibition on cardiac gene expression after acute myocardial infarction
Circulation, ISSN: 00097322
Hongkui Jin; Renhui Yang; Tarif A. Awad; Fay Wang; Wei Li; Simon P. Williams; Annie Ogasawara; Brian Shimada; P. Mickey Williams; Gianfranco De Feo; Nicholas F. Paoni
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