Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11451 - 11500 OF 15396 RESULTS

Analysis of biological effects and signaling properties of Flt-1 (VEGFR-1) and KDR (VEGFR-2): A reassessment using novel receptor-specific vascular endothelial growth factor mutants
Journal of Biological Chemistry, ISSN: 00219258
Hendrik Gille; Joe Kowalski; Bing Li; Jennifer Lecouter; Moffat; Zioncheck; Nicolas Pelletier; Napoleone Ferrara
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Bispecific human IgG by design
Journal of Immunological Methods, ISSN: 00221759
Paul J. Carter
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Untangling the ErbB signalling network
Nature Reviews Molecular Cell Biology, ISSN: 14710072
Yarden; Mark X. Sliwkowski
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A minimal peptide scaffold for β-turn display: Optimizing a strand position in disulfide-cyclized β-hairpins
Journal of the American Chemical Society, ISSN: 00027863
Andrea G Cochran; Tong; Melissa A. Starovasnik; Park; Robert S. McDowell; Theaker; Nicholas J. Skelton
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The tissue factor region that interacts with factor Xa in the activation of factor VII
Biochemistry, ISSN: 00062960
Daniel Kirchhofer; Eigenbrot; Michael T. Lipari; Paul Moran; Peek; Robert F. Kelley
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Engraftment of autologous retrovirally transduced hepatocytes after intraportal transplantation into nonhuman primates: Implication for ex vivo gene therapy
Human Gene Therapy, ISSN: 10430342
Andreoletti; Nathalie Loux; Corinne Vons; Tuan Huy Nguyen; Lorand; Mahieu; Simon; Di Rico; Vingert; Chapman; Pascale Briand; Ralph H. Schwall; Hamza; Capron; Bargy; Dominique Franco; Anne Weber
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Overexpression of the human 2-oxoglutarate carrier lowers mitochondrial membrane potential in HEK-293 cells: Contrast with the unique cold-induced mitochondrial carrier CGI-69
Biochemical Journal, ISSN: 02646021
Yu; Lewin; Zhong; Brush; Peter Schow; Steve Sherwood; Pan; Adams
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Membrane ion-exchange chromatography for process-scale antibody purification
Journal of Chromatography A, ISSN: 00219673
Knudsen; Fahrner; Yuan Xu; Lenore A Norling; Gregory S. Blank
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The RelA(p65) subunit of NF-κB is essential for inhibiting double-stranded RNA-incluced cytotoxicity
Journal of Biological Chemistry, ISSN: 00219258
Ming Li; Wendy Shillinglaw; William J. Henzel; Amer A. Beg
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IL-17E, a novel proinflammatory ligand for the IL-17 receptor homolog IL-17Rh1
Journal of Biological Chemistry, ISSN: 00219258
James Lee; Ho; Maruoka; Corpuz; Daryl T. Baldwin; Foster; Goddard; Yansura; Richard L. Vandlen; William I. Wood; Austin L. Gurney
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IL-1H, an interleukin 1-related protein that binds IL-18 receptor/IL-1Rrp
Cytokine, ISSN: 10434666
Pan; Risser; Mao; Daryl T. Baldwin; Zhong; Ellen H. Filvaroff; Yansura; Lhney Lewis; Eigenbrot; William J. Henzel; Richard L. Vandlen
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Adherence of multiple myeloma cells to bone marrow stromal cells upregulates vascular endothelial growth factor secretion: Therapeutic applications
Leukemia, ISSN: 08876924
Gupta; Treon; Shima; Hideshima; Podar; Tai; Lin; Lentzsch; Davies; Chauhan; Schlossman; Paul Richardson; Peter Ralph; Wu; Payvandi; Muller; Stirling; Anderson
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Structural requirements for ErbB2 transactivation
Seminars in Oncology, ISSN: 00937754
Elicia M. Penuel; Gabriele Schaefer; Robert W. Akita; Mark X. Sliwkowski
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Novel non-isotopic method for the localization of receptors in tissue sections
Journal of Histochemistry and Cytochemistry, ISSN: 00221554
Luc Desnoyers; Rebecca A. Simonette; Richard L. Vandlen; Brian M. Fendly
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Pathways by which interleukin 17 induces articular cartilage breakdown in vitro and in vivo
Cytokine, ISSN: 10434666
Liping Cai; Jianping Yin; Melissa A. Starovasnik; Deborah A. Hogue; Kenneth J. Hillan; John S. Mort; Ellen H. Filvaroff
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Vascular endothelial cell growth factor-driven endothelial tube formation is mediated by vascular endothelial cell growth factor receptor-2, a kinase insert domain-containing receptor
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642
Suya Yang; Xiaohua Xin; Constance Zlot; Gladys S. Ingle; Fuh; Bing Li; Moffat; De Vos; Mary E. Gerritsen
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A two-year randomized, placebo-controlled trial of dornase alfa in young patients with cystic fibrosis with mild lung function abnormalities
Journal of Pediatrics, ISSN: 00223476
Joanne M. Quan; Harm A.W.M. Tiddens; Judy P. Sy; Sheila G. McKenzie; Mark D. Montgomery; Philip J. Robinson; Mary Ellen Wohl; Michael W. Konstan
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The treatment of moderate to severe psoriasis with a new anti-CD11a monoclonal antibody
Journal of the American Academy of Dermatology, ISSN: 01909622
Kim Papp; Robert Bissonnette; James G. Krueger; Wayne Carey; David Gratton; Wayne P. Gulliver; Harvey Lui; Charles W. Lynde; Anna Magee; Daniel Minier; Jean P. Ouellet; Piyush Patel; Jerry Shapiro; Neil H. Shear; Susan Kramer; Patricia Walicke; Bauer; Russell L Dedrick; Sun Sook Kim; Mark White; Marvin Garovoy
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A multicenter study of the efficacy and safety of sustained release GH in the treatment of naive pediatric patients with GH deficiency
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Edward O. Reiter; Kenneth M. Attie; Thomas Moshang Jr.; Bernard L. Silverman; Stephen F. Kemp; Rachel B. Neuwirth; Kathleen M. Ford; Saenger
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Intracoronary administration of recombinant human vascular endothelial growth factor to patients with coronary artery disease
American Heart Journal, ISSN: 00028703
Timothy D. Henry; Krishna Rocha-Singh; Jeffrey M. Isner; Dean J. Kereiakes; Frank J. Giordano; Michael Simons; Douglas W. Losordo; Robert C. Hendel; Robert O. Bonow; Stephen M. Eppler; Zioncheck; Holmgren; Edward R. McCluskey
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Advanced coronary artery disease: Appropriate end points for trials of novel therapies
American Heart Journal, ISSN: 00028703
David E. Kandzari; La Choi Lam; Eric L. Eisenstein; Nancy Clapp-Channing; Jennifer T. Fine; Robert M. Califf; Daniel B. Mark; James G. Jollis
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Anti-CD11a ameliorates disease in the human psoriatic skin-SCID mouse transplant model: Comparison of antibody to CD11a with cyclosporin a and clobetasol propionate
Laboratory Investigation, ISSN: 00236837
Mary Zeigler; Yiqing Chi; Daniel B. Tumas; Bodary; Haicheng Tang; James Varani
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Underutilization of reperfusion therapy in eligible African Americans with acute myocardial infarction: Role of presentation and evaluation characteristics
American Heart Journal, ISSN: 00028703
Ajay Manhapra; John G. Canto; Hal V. Barron; Judith A. Malmgren; Herman Taylor; William J. Rogers; W.Douglas Weaver; Nathan R. Every; Steven Borzak
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Gene profiling techniques and their application in angiogenesis and vascular development
Journal of Pathology, ISSN: 00223417
Franklin V. Peale Jr.; Mary E. Gerritsen
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Encapsulation and stabilization of nerve growth factor into poly(lactic-co-glycolic) acid microspheres
Journal of Pharmaceutical Sciences, ISSN: 00223549
Lam; Duenas; Cleland
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Effect of moisture on the stability of a lyophilized humanized monoclonal antibody formulation
Pharmaceutical Research, ISSN: 07248741
Breen; Curley; David E. Overcashier; Chung C. Hsu; Steven J. Shire
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Combinatorial chemistry in steroid receptor drug discovery.
Methods in Molecular Biology, ISSN: 10643745
Flygare; Daniel P. Sutherlin; Brown
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Use of reperfusion therapies in elderly patients with acute myocardial infarction
Drugs and Aging, ISSN: 1170229X
Brad G. Angeja; C.Michael Gibson; Richard Chin; John G. Canto; Hal V. Barron
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Industrial purification of pharmaceutical antibodies: Development, operation, and validation of chromatography processes
Biotechnology and Genetic Engineering Reviews, ISSN: 02648725
Fahrner; Knudsen; Basey; Walter Galan; Feuerhelm; Vanderlaan; Gregory S. Blank
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Engineering M13 for phage display
Biomolecular Engineering, ISSN: 13890344
Sachdev S. Sidhu
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Recombinant tissue plasminogen activator (alteplase) for restoration of flow in occluded central venous access devices: A double-blind placebo-controlled trial - The cardiovascular thrombolytic to open occluded lines (COOL) efficacy trial
Journal of Vascular and Interventional Radiology, ISSN: 10510443
Ponec; David Irwin; Haire; Hill; Xin Li; Edward R. McCluskey
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Angiogenesis and chronic disease
Trends in Molecular Medicine, ISSN: 14714914
Mary E. Gerritsen
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Alteplase and tenecteplase: Applications in the peripheral circulation
Techniques in Vascular and Interventional Radiology, ISSN: 10892516
Charles P. Semba; Koji Sugimoto; Mahmood K Razavi
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Genetic variation in physiological sensitivity to estrogen in mice
APMIS, ISSN: 09034641
Jimmy L. Spearow; Peter O'Henley; Paul Doemeny; Robyn Sera; Rachael Leffler; Taki Sofos; Marylynn Barkley
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Role of vascular endothelial growth factor in regulation of physiological angiogenesis
American Journal of Physiology - Cell Physiology, ISSN: 03636143
Napoleone Ferrara
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Nerve growth factor: Structure and function
Cellular and Molecular Life Sciences, ISSN: 1420682X
Wiesmann; De Vos
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Anti-IgE efficacy in murine asthma models is dependent on the method of allergen sensitization
Journal of Allergy and Clinical Immunology, ISSN: 00916749
Daniel B. Tumas; Betty Chan; Winifred R. Werther; Wrin; Vennari; Noelyn Desjardin; Robert L. Shields; Paula Jardieu
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Activation of expression of hedgehog target genes in basal cell carcinomas
Journal of Investigative Dermatology, ISSN: 0022202X
Jeannette M. Bonifas; Sally Pennypacker; Pao-Tien Chuang; Andrew P. McMahon; Mickey P. Williams; Rosenthal; Frederic J. De Sauvage; Ervin H. Epstein Jr.
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The use of intra-aortic balloon counterpulsation in patients with cardiogenic shock complicating acute myocardial infarction: Data from the national registry of myocardial infarction 2
American Heart Journal, ISSN: 00028703
Hal V. Barron; Nathan R. Every; Lori Parsons; Brad G. Angeja; Robert J. Goldberg; Joel M. Gore; Tony M. Chou
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Cardiology Clinics: Preface
Cardiology Clinics, ISSN: 07338651
Jagat Narula; Vishva M. Dixit; Leslie W. Miller
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Effects of in vivo heregulin β1 treatment in wild-type and ErbB gene-targeted mice depend on receptor levels and pregnancy
American Journal of Pathology, ISSN: 00029440
Sue O'Shea; Kent J. Johnson; Ross Clark; Mark X. Sliwkowski; Sharon Erickson
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Growth of children in two economically diverse Peruvian high-altitude communities
American Journal of Human Biology, ISSN: 10420533
Pawson; Huicho; Muro; Pacheco
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Acute coronary syndromes
Annals of Emergency Medicine, ISSN: 01960644
Thomas Aufderheide; Leo L. Bossaert; John Field; Johan Herlitz; Alain Leizorovicz; Katherine A. Littrell; Joseph P. Ornato; Mary Ann Peberdy; Flavio Ribichini
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Matrix-assisted laser desorption/ionization time-of-flight mass analysis of peptides.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.], ISSN: 19343663
William J. Henzel; Stults
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Concordance for Type 1 Diabetes in Identical Twins Is Affected by Insulin Genotype
Diabetes Care, ISSN: 01495992
Karl A. Metcalfe; Graham A. Hitman; Rachel E. Rowe; Mohammed Hawa; Huang; Stewart; R. David G. Leslie
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Induction of gp91-phox, a component of the phagocyte NADPH oxidase, in microglial cells during central nervous system inflammation
Journal of Cerebral Blood Flow and Metabolism, ISSN: 0271678X
Green; Cairns; Julie Rae; Errett-Baroncini; Hongo; Erickson; John T. Curnutte
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CD62L is required on effector cells for local interactions in the CNS to cause myelin damage in experimental allergic encephalomyelitis
Immunity, ISSN: 10747613
Iqbal S. Grewal; Harald G. Foellmer; Kate D. Grewal; Hua Wang; Wyne P. Lee; Daniel B. Tumas; Charles A. Janeway Jr.; Richard A. Flavell
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Vitamin a intake affects the contribution of chylomicrons vs. Retinol-binding protein to milk vitamin A in lactating rats
Journal of Nutrition, ISSN: 00223166
Michael H. Green; Joanne Balmer Green; Sylvie A. Akohoue; Sean K. Kelley
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Terms of reference for Data and Safety Monitoring Committees
American Heart Journal, ISSN: 00028703
Milton Packer; Janet Wittes; David Stump
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Generation of a humanized, high affinity anti-tissue factor antibody for use as a novel antithrombotic therapeutic
Thrombosis and Haemostasis, ISSN: 03406245
Presta; Paul Sims; Meng; Paul Moran; Sherron L. Bullens; Bunting; Schoenfeld; David G Lowe; Lai; Rancatore; Iverson; Lim; Chisholm; Robert F. Kelley; Markus A. Riederer; Daniel Kirchhofer
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