Genentech: Publications

December 1, 2000

Drinks like a fish: Zebra fish (Danio rerio) as a behavior genetic model to study alcohol effects

Pharmacology Biochemistry and Behavior, ISSN: 00913057

Gerlai; Lahav; Guo; Rosenthal

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December 1, 2000

Angiogenesis and bone growth

Trends in Cardiovascular Medicine, ISSN: 10501738

Hans-Peter Gerber; Napoleone Ferrara

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December 1, 2000

Optimizing the use of rituximab for treatment of B-cell non-Hodgkin's lymphoma: A benefit-risk update

Seminars in Oncology, ISSN: 00937754

Lori Kunkel; Anne Wong; Thomas J. Maneatis; Nickas; Brown; Grillo-Lopez; Benyunes; Barry Grobman; Dillman

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December 1, 2000

Consensus guidelines for the diagnosis and treatment of growth hormone (GH) deficiency in childhood and adolescence: Summary statement of the GH research society

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X

Kenneth M. Attie; Bengt-Ake Bengtsson; Sandra L. Blethen; Werner Blum; Fergus Cameron; Jean Claude Carel; Carlsson; John J. Chipman; Jens Sandahl Christiansen; Peter E. Clayton; David R. Clemmons; Pinchas Cohen; Stenvert Drop; Kenji Fujieda; Ezio Ghigo; Hintz; Ken Ho; Mapoko M. Ilondo; Hector Jasper; Bernd Jesussek; Anne-Marie Kappelgaard; Laron; Barbara M. Lippe; Saul Malozowski; Primus E. Mullis; Sabine De Muinck-Keizer-Schrama; Yoshikazu Nishi; John S. Parks; Charlotte Phelps; Michael Ranke; Icaf Robinson; Rosenfeld; Susan Rose; Saenger; Guissepe Saggese; Martin Savage; Stephen Shalet; Pierre C. Sizonenko; Christian Strasburger; Katsuhiko Tachibana; Toshiaki Tanaka; Michael O. Thorner; Kerstin Albertsson-Wikland; Zvi Zadik

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December 1, 2000

A potential role for activated HER-2 in prostate cancer

Seminars in Oncology, ISSN: 00937754

David B. Agus; Robert W. Akita; Fox; Julie A. Lofgren; Higgins; Maiese; Scher; Mark X. Sliwkowski

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November 16, 2000

A regulator of transcriptional elongation controls vertebrate neuronal development

Nature, ISSN: 00280836

Guo; Yuki Yamaguchi; Sarah Schilbach; Tadashi Wada; James Lee; Goddard; French; Hiroshi Handa; Rosenthal

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November 13, 2000

Two-amino acid molecular switch in an epithelial morphogen that regulates binding to two distinct receptors

Science, ISSN: 00368075

Minhong Yan; Li-Chong Wang; Sarah G. Hymowitz; Sarah Schilbach; James Lee; Goddard; De Vos; Gao; Vishva M. Dixit

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November 10, 2000

Activation and active site occupation alter conformation in the region of the first epidermal growth factor-like domain of human factor VII

Journal of Biological Chemistry, ISSN: 00219258

Blair J. N. Leonard; Bryan J. Clarke; Sampath Sridhara; Robert F. Kelley; Fred A. Ofosu; Morris A. Blajchman

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November 10, 2000

c-Cbl is a suppressor of the Neu oncogene

Journal of Biological Chemistry, ISSN: 00219258

Gil Levkowitz; Shlomo Oved; Leah N. Klapper; Daniel Harari; Sara Lavi; Michael Sela; Yarden

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November 7, 2000

Structural preordering in the N-terminal region of ribosomal protein S4 revealed by heteronuclear NMR spectroscopy

Biochemistry, ISSN: 00062960

Sayers; Gerstner; Draper; Torchia

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November 6, 2000

Structure-based design of six novel classes of nonpeptide antagonists of the bradykinin B2 receptor

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

Dean R. Artis; Christine Brotherton-Pleiss; Joseph H. Pease; Clara J. Lin; Steve W. Ferla; Sherry R. Newman; Sunil Bhakta; Helene Ostrelich; Kurt Jarnagin

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November 2, 2000

ML-IAP, a novel inhibitor of apoptosis that is preferentially expressed in human melanomas

Current Biology, ISSN: 09609822

Domagoj Vucic; Henning R. Stennicke; Pisabarro; Guy S. Salvesen; Vishva M. Dixit

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November 1, 2000

Cleavage and identification of proteins: A modified aspartyl-prolyl cleavage

Analytical Chemistry, ISSN: 00032700

Kishiyama; Zemin Zhang; William J. Henzel

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November 1, 2000

Effects of VEGF on hemodynamics and cardiac function: Characterization and mechanisms

IDrugs, ISSN: 13697056

Renhui Yang; Bunting; Hongkui Jin

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November 1, 2000

Effect of IFN-γ on the killing of S. aureus in human whole blood: Assessment of bacterial viability by CFU determination and by a new method using alamarBlue

Journal of Immunological Methods, ISSN: 00221759

Laura DeForge; Karen L Billeci; Susan M. Kramer

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October 30, 2000

Gli regulation by the opposing activities of fused and suppressor of fused

Nature Cell Biology, ISSN: 14657392

Maximilien Murone; Shiuh-Ming Luoh; Donna Stone; Wenlu Li; Austin L. Gurney; Armanini; Christa Grey; Rosenthal; Frederic J. De Sauvage

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October 19, 2000

Development of Th1-type immune responses requires the type I cytokine receptor TCCR

Nature, ISSN: 00280836

Qi Chen; Nico Ghilardi; Hua Wang; Thad Baker; Xie; Austin L. Gurney; Iqbal S. Grewal; Frederic J. De Sauvage

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October 15, 2000

Inhibition of HER2/neu (erbB-2) and mitogen-activated protein kinases enhances tamoxifen action against HER2-overexpressing, tamoxifen-resistant breast cancer cells

Cancer Research, ISSN: 00085472

Hirokazu Kurokawa; Anne E. G. Lenferink; Jean F. Simpson; Paul Pisacane; Mark X. Sliwkowski; James T. Forbes; Carlos L. Arteaga

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October 6, 2000

Interleukin (IL)-22, a novel human cytokine that signals through the interferon receptor-related proteins CRF2-4 and IL-22R

Journal of Biological Chemistry, ISSN: 00219258

Xie; Aggarwal; Ho; Foster; Zhang; Stinson; William I. Wood; Goddard; Austin L. Gurney

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October 5, 2000

Multiple cell culture factors can affect the glycosylation of Asn-184 in CHO-produced tissue-type plasminogen activator

Biotechnology and Bioengineering, ISSN: 00063592

Dana C. Andersen; Tiffany Bridges; Martin Gawlitzek; Cynthia Hoy

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October 1, 2000

Achieving neuronal patterning by repression

Nature Neuroscience, ISSN: 10976256

Donna Stone; Rosenthal

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September 29, 2000

ICEBERG: A novel inhibitor of interleukin-1β generation

Cell, ISSN: 00928674

Eric W. Humke; Stephanie K. Shriver; Melissa A. Starovasnik; Wayne J. Fairbrother; Vishva M. Dixit

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September 28, 2000

Tethering of CpxP to the inner membrane prevents spheroplast induction of the Cpx envelope stress response

Molecular Microbiology, ISSN: 0950382X

Tracy L. Raivio; Mike Laird; John C. Joly; Thomas J. Silhavy

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September 27, 2000

The G-protein inhibitor, pertussis toxin, inhibits the secretion of brain-derived neurotrophic factor

Neuroscience, ISSN: 03064522

Gunther; Von Bartheld; Goodman; Johnson; Bothwell

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September 22, 2000

The coiled-coil domain of occludin can act to organize structural and functional elements of the epithelial tight junction

Journal of Biological Chemistry, ISSN: 00219258

Asma Nusrat; Jason A. Chen; Chris S. Foley; Tony W. Liang; Jeffrey Tom; Cromwell; Quan; Mrsny

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September 22, 2000

Receptor-selective variants of human vascular endothelial growth factor. Generation and characterization

Journal of Biological Chemistry, ISSN: 00219258

Bing Li; Fuh; Meng; Xiaohua Xin; Mary E. Gerritsen; Cunningham; De Vos

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September 15, 2000

Deficiency of T2K leads to apoptotic liver degeneration and impaired NF-κB-dependent gene transcription

EMBO Journal, ISSN: 02614189

Madeleine Bonnard; Christine Mirtsos; Shinobu Suzuki; Kevin Graham; Jianing Huang; Michelle Ng; Annick Itié; Andrew Wakeham; Arda Shahinian; William J. Henzel; Andrew J. Elia; Wendy Shillinglaw; Tak W. Mak; Zhaodan Cao; Wen-Chen Yeh

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September 15, 2000

MDM2 interacts with the C-terminus of the catalytic subunit of DNA polymerase ε

Nucleic Acids Research, ISSN: 03051048

Nikolina Vlatkovic; Stephanie Guerrera; Ying Li; Stuart Linn; Dale S. Haines; Mark T. Boyd

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September 4, 2000

Statistical analysis of the long-term effects of recombinant human deoxyribonuclease on pulmonary function in cystic fibrosis patients

Journal of Biopharmaceutical Statistics, ISSN: 10543406

John J. Chen; Scott A. Hamilton

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September 4, 2000

Statistical analysis of the long-term effects of recombinant human deoxyribonuclease on pulmonary function in cystic fibrosis patients

Journal of Biopharmaceutical Statistics, ISSN: 10543406

John J. Chen; Scott Hamilton

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September 2, 2000

Wnt signaling and cancer

Genes and Development, ISSN: 08909369

Paul G. Polakis

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September 1, 2000

A comparison of different methods to determine the end of exponential growth in CHO cell cultures for optimization of scale-up

Biotechnology Progress, ISSN: 87567938

Schoenherr; Stapp; Thomas Ryll

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September 1, 2000

The interaction of neuropilin-1 in vascular endothelial growth factor and its receptor Flt-1

Journal of Biological Chemistry, ISSN: 00219258

Fuh; Garcia; De Vos

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September 1, 2000

Efficient phage display of polypeptides fused to the carboxy-terminus of the M13 gene-3 minor coat protein

FEBS Letters, ISSN: 00145793

Fuh; Sachdev S. Sidhu

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September 1, 2000

Ternary complex between placental lactogen and the extracellular domain of the prolactin receptor

Nature Structural Biology, ISSN: 10728368

Patricia A. Elkins; Hans W. Christinger; Yael Sandowski; Edna Sakal; Arieh Gertler; De Vos; Anthony A. Kossiakoff

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August 26, 2000

Antibody binding regions on human nerve growth factor identified by homolog- and alanine-scanning mutagenesis

Hybridoma, ISSN: 0272457X

Hongo; Laramee; Urfer; David L. Shelton; Restivo; Michael D Sadick; Galloway; Chu; Winslow

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August 25, 2000

Smoothened activates Gα(i)-mediated signaling in frog melanophores

Journal of Biological Chemistry, ISSN: 00219258

Dianne L. DeCamp; Teresa M. Thompson; Frederic J. De Sauvage; Michael R. Lerner

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August 20, 2000

Performance of small-scale CHO perfusion cultures using an acoustic cell filtration device for cell retention: Characterization of separation efficiency and impact of perfusion on product quality

Biotechnology and Bioengineering, ISSN: 00063592

Thomas Ryll; George Dutina; Arthur Reyes; Jane Gunson; Lynne Krummen; Etcheverry

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August 18, 2000

Vitronectin receptor antagonists: Purine-based peptidomimetics

Angewandte Chemie - International Edition, ISSN: 14337851

Peyman; Gourvest; Thomas Gadek; Knolle

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August 18, 2000

Enzyme mechanisms for polycyclic triterpene formation

Angewandte Chemie - International Edition, ISSN: 14337851

K. Ulrich Wendt; Georg E. Schulz; Elias J. Corey; David R. Liu

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August 15, 2000

VEGF regulates cell behavior during vasculogenesis

Developmental Biology, ISSN: 00121606

Christopher J. Drake; Amanda LaRue; Napoleone Ferrara; Charles D. Little

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August 11, 2000

The 3' UTR of human MnSOD mRNA hybridizes to a small cytoplasmic RNA and inhibits gene expression

Biochemical and Biophysical Research Communications, ISSN: 0006291X

Joseph J. Stuart; Levente A. Egry; Grace H.W. Wong; Roger L. Kaspar

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August 2, 2000

Genetic studies in idiopathic short stature

Current Opinion in Pediatrics, ISSN: 10408703

Kenneth M. Attie

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August 1, 2000

Rapid mapping of protein functional epitopes by combinatorial alanine scanning

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Gregory A. Weiss; Colin K. Watanabe; Zhong; Goddard; Sachdev S. Sidhu

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August 1, 2000

Electrophoretic methods for the analysis of N-linked oligosaccharides

Analytical Biochemistry, ISSN: 00032697

T. Shantha Raju

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August 1, 2000

FIZZ1, a novel cysteine-rich secreted protein associated with pulmonary inflammation, defines a new gene family

EMBO Journal, ISSN: 02614189

Ilona N. Holcomb; Rhona C. Kabakoff; Betty Chan; Thad Baker; Austin L. Gurney; William J. Henzel; Nelson; Henry B. Lowman; Wright; Nicholas J. Skelton; Gretchen D. Frantz; Daniel B. Tumas; Franklin V. Peale Jr.; David L. Shelton; Hébert

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August 1, 2000

A repressor sequence in the juxtamembrane domain of Flt-1 (VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3'-kinase activation and endothelial cell migration

EMBO Journal, ISSN: 02614189

Hendrik Gille; Joe Kowalski; Lanlan Yu; Helen Chen; Pisabarro; Terri Davis-Smyth; Napoleone Ferrara

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August 1, 2000

Analysis of glycoconjugates: II. Electrophoresis

Analytical Biochemistry, ISSN: 00032697

T. Shantha Raju

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July 28, 2000

Identification and cloning of two histone fold motif-containing subunits of HeLa DNA polymerase ε

Journal of Biological Chemistry, ISSN: 00219258

Ying Li; Zachary F. Pursell; Stuart Linn

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July 27, 2000

Fringe is a glycosyltransferase that modifies Notch

Nature, ISSN: 00280836

Daniel J. Moloney; Vladislav M. Panin; Stuart H. Johnston; Jihua Chen; Li Shao; Richa Wilson; Yang Wang; Pamela Stanley; Kenneth D. Irvine; Robert S. Haltiwanger; Thomas F. Vogt

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