Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11601 - 11650 OF 15396 RESULTS

Increased binding activity at an antioxidant-responsive element in the metallothionein-1 promoter and rapid induction of metallothionein-1 and -2 in response to cerebral ischemia and reperfusion
Journal of Neuroscience, ISSN: 02706474
Menno Van Lookeren Campagne; Harold Thibodeaux; Nicholas Van Bruggen; Cairns; David G Lowe
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Analysis of PDZ domain-ligand interactions using carboxyl-terminal phage display
Journal of Biological Chemistry, ISSN: 00219258
Fuh; Pisabarro; Ying Li; Quan; Lasky; Sachdev S. Sidhu
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Interaction of the tumor suppressor PTEN/MMAC with a PDZ domain of MAGI3, a novel membrane-associated guanylate kinase
Journal of Biological Chemistry, ISSN: 00219258
Yan Wu; Dowbenko; Spencer; Richard Laura; James Lee; Qimin Gu; Lasky
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Purification of plasmid DNA by tangential flow filtration
Biotechnology and Bioengineering, ISSN: 00063592
David W. Kahn; Michelle D. Butler; Darien L. Cohen; Margaret Gordon; Jeanne Kahn; Winkler
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Sustained release of recombinant human insulin-like growth factor-I for treatment of diabetes
Journal of Controlled Release, ISSN: 01683659
Lam; Duenas; Daugherty; Nancy Levin; Cleland
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The apoptotic signaling pathway activated by Toll-like receptor-2
EMBO Journal, ISSN: 02614189
Antonios O. Aliprantis; Ruey-Bing Yang; David S. Weiss; Godowski; Arturo Zychlinsky
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Broad specificity of GDNF family receptors GFRα1 and GFRα2 for GDNF and NTN in neurons and transfected cells
Journal of Neuroscience Research, ISSN: 03604012
Li-Chong Wang; Shih; Hongo; Devaux; Mary Hynes
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Design evolution of artificial M13 coat proteins
Journal of Molecular Biology, ISSN: 00222836
Gregory A. Weiss; Sachdev S. Sidhu
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Modulation of tight junction function by G protein-coupled events
Advanced Drug Delivery Reviews, ISSN: 0169409X
Ann M. Hopkins; Dinxi Li; Mrsny; Shaun V. Walsh; Asma Nusrat
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Development and qualification of a novel virus removal filter for cell culture applications
Biotechnology Progress, ISSN: 87567938
Shengjiang Liu; Mark Carroll; Raquel Iverson; Christine Valera; Vennari; Kimberly Turco; Robert Piper; Robert Kiss; Herbert Lutz
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Prevalence, clinical characteristics, and mortality among patients with myocardial infarction presenting without chest pain
JAMA - Journal of the American Medical Association, ISSN: 00987484
John G. Canto; Michael G. Shlipak; William J. Rogers; Judith A. Malmgren; Paul D. Frederick; Costas Lambrew; Joseph P. Ornato; Hal V. Barron; Calarina I. Kiefe
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The tissue factor region that interacts with substrates factor IX and factor X
Biochemistry, ISSN: 00062960
Daniel Kirchhofer; Michael T. Lipari; Paul Moran; Eigenbrot; Robert F. Kelley
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Ammonium alters N-glycan structures of recombinant TNFR-IgG: Degradative versus biosynthetic mechanisms
Biotechnology and Bioengineering, ISSN: 00063592
Martin Gawlitzek; Thomas Ryll; James A. Lofgren; Mary B. Sliwkowski
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A phase II study of two HIV type 1 envelope vaccines, comparing their immunogenicity in populations at risk for acquiring HIV type 1 infection
AIDS Research and Human Retroviruses, ISSN: 08892229
M. Juliana McElrath; Lawrence Corey; David Montefiori; Mark Wolff; David Schwartz; Michael C. Keefer; Robert Belshe; Barney S. Graham; Matthews; Peter Wright; Geoffrey Gorse; Raphael Dolin; Berman; Francis; A-M. Duliege; Dani P. Bolognesi; Donald M. Stablein; Nzeera Ketter; Patricia Fast
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Cockroach diuretic hormones: Characterization of a calcitonin-like peptide in insects
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Kenji Furuya; Richard J. Milchak; Kathleen M. Schegg; Jinrui Zhang; Stephen S. Tobe; Geoffrey M. Coast; David A. Schooley
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VEGF nuclear accumulation correlates with phenotypical changes in endothelial cells
Journal of Cell Science, ISSN: 00219533
Wenlu Li; Gilbert-Andre Keller
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Interaction of the TNF homologues BLyS and APRIL with the TNF receptor homologues BCMA and TACI
Current Biology, ISSN: 09609822
Scot A. Marsters; Minhong Yan; Pitti; Philip E. Haas; Vishva M. Dixit; Avi Ashkenazi
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Immunopolymerase chain reaction using real-time polymerase chain reaction for detection
Analytical Biochemistry, ISSN: 00032697
Paul Sims; Vasser; Wai Lee T. Wong; P. Mickey Williams; Meng
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Variations on ligand-receptor complexes
Nature Structural Biology, ISSN: 10728368
Wiesmann; De Vos
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ABRF-98SEQ: Evaluation of peptide sequencing at high sensitivity
Journal of Biomolecular Techniques, ISSN: 15240215 19434731
William J. Henzel; Arie Admon; Steve A. Carr; Gary Davis; Karen De Jongh; William Lane; Michael Rohd; Laurey Steinke
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Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears
Nature Neuroscience, ISSN: 10976256
Zheng; Gao
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The volume of primary angioplasty procedures and survival after acute myocardial infarction
New England Journal of Medicine, ISSN: 00284793
John G. Canto; Nathan R. Every; David J. Magid; William J. Rogers; Judith A. Malmgren; Paul D. Frederick; William J. French; Alan J. Tiefenbrunn; Vijay K. Misra; Calarina I. Kiefe; Hal V. Barron
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Evidence for the involvement of histidine A(12) in the aggregation and precipitation of human relaxin induced by metal-catalyzed oxidation
Biochemistry, ISSN: 00062960
Mehrnaz Khossravi; Steven J. Shire; Ronald T. Borchardt
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Radiation and the Apo2L/TRAIL apoptotic pathway preferentially inhibit the colonization of premalignant human breast cells overexpressing cyclin D1
Cancer Research, ISSN: 00085472
Qun Zhou; Paula Fukushima; William DeGraff; James B. Mitchell; Maryalice Stetler-Stevenson; Avi Ashkenazi; Patricia S. Steeg
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Stability and interactions of recombinant human nerve growth factor in different biological matrices: In vitro and in vivo studies
Drug Metabolism and Disposition, ISSN: 00909556
Cindy B. Nguyen; Szonyi; Michael D Sadick; Hotaling; José-Luis Mendoza-Ramírez; Escandon
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Tissue disposition and pharmacokinetics of recombinant human nerve growth factor after acute and chronic subcutaneous administration in monkeys
Drug Metabolism and Disposition, ISSN: 00909556
Cindy B. Nguyen; Louise A. Harris; Szonyi; Sharon A. Baughman; Victoria Hale; Noel Dybdal; Michael D Sadick; Escandon
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Structural basis of the Axin-adenomatous polyposis coli interaction
EMBO Journal, ISSN: 02614189
Katharine Eklof Spink; Paul G. Polakis; William I. Weis
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Pharmacokinetics, tissue distribution, metabolism, and excretion of celecoxib in rats
Drug Metabolism and Disposition, ISSN: 00909556
Susan K. Paulson; Ji Y. Zhang; Alan P. Breau; Jeremy D. Hribar; Norman W. K. Liu; Susan M. Jessen; Yvette M. Lawal; J. Nita Cogburn; Christopher J. Gresk; Charles S. Markos; Timothy J. Maziasz; Grant L. Schoenhard; Earl G. Burton
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Growth factors: Formation of endothelial cell networks
Nature, ISSN: 00280836
Gabriel Helmlinger; Mitsuhiro Endo; Napoleone Ferrara; Lynn Hlatky; Rakesh K. Jain
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Claims of equivalence in medical research: Are they supported by the evidence?
Annals of Internal Medicine, ISSN: 00034819
William L. Greene; John Concato; Alvan R. Feinstein
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Heregulin, but not ErbB2 or ErbB3, heterozygous mutant mice exhibit hyperactivity in multiple behavioral tasks
Behavioural Brain Research, ISSN: 01664328
Gerlai; Paul Pisacane; Sharon Erickson
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AIDSVAX® (MN) in Bangkok injecting drag users: A report on safety and immunogenicity, including macrophage-tropic virus neutralization
AIDS Research and Human Retroviruses, ISSN: 08892229
Sricharoen Migasena; Pravan Suntharasamai; Punnee Pitisuttithum; Dwip Kitayaporn; Chantapong Wasi; Wei Huang; Suphak Vanichseni; Charnchai Koompong; Jaranit Kaewkungwal; Suwanee Raktham; Tina Ippolito; Hanson; Timothy Gregory; William L. Heyward; Berman; Francis
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Structure of chromosomal duplicons and their role in mediating human genomic disorders
Genome Research, ISSN: 10889051
Yonggang Ji; Evan E. Eichler; Stuart Schwartz; Robert D. Nicholls
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Expression of the chemokine receptor CXCR2 in normal and neoplastic neuroendocrine cells
Archives of Pathology and Laboratory Medicine, ISSN: 00039985
Tülay Tecimer; Jeffrey Dlott; Anan Chuntharapai; Alvin W. Martin; Stephen C. Peiper
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Application of cDNA microarrays in determining molecular phenotype in cardiac growth, development, and response to injury
Circulation, ISSN: 00097322
Sehl; Julie Tsu-Ning Tai; Kenneth J. Hillan; Lesley A. Brown; Goddard; Renhui Yang; Hongkui Jin; David G Lowe
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Mapping of the C1q binding site on rituxan, a chimeric antibody with a human IgG1 Fc
Journal of Immunology, ISSN: 00221767
Esohe E. Idusogie; Presta; Hélène Gazzano-Santoro; Klara Totpal; Pin-Yee Wong; Ultsch; Meng; Michael G. Mulkerrin
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Characterization of calcium release-activated apoptosis of LNCaP prostate cancer cells
Journal of Biological Chemistry, ISSN: 00219258
Ingrid E. Wertz; Vishva M. Dixit
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Quantitative expression analysis of genes regulated by both obesity and leptin reveals a regulatory loop between leptin and pituitary-derived ACTH
Journal of Biological Chemistry, ISSN: 00219258
Renz; Elizabeth Tomlinson; Hultgren; Nancy Levin; Qimin Gu; Richard A. Shimkets; Lewin; Stewart
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Identification of the mechanism responsible for the increased fibrin specificity of TNK-tissue plasminogen activator relative to tissue plasminogen activator
Journal of Biological Chemistry, ISSN: 00219258
Ronald J. Stewart; James C. Fredenburgh; Beverly A. Leslie; Keyt; Janice A. Rischke; Jeffrey I. Weitz
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Deciphering the role of the electrostatic interactions involving Gly70 in eglin c by total chemical protein synthesis
Biochemistry, ISSN: 00062960
Wei-Yue Lu; Melissa A. Starovasnik; John J. Dwyer; Anthony A. Kossiakoff; Stephen B. H. Kent; Wuyuan Lu
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Antagonists of protein-protein interactions
Chemistry and Biology, ISSN: 10745521
Andrea G Cochran
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Conditional inactivation of VEGF-A in areas of collagen2a1 expression results in embryonic lethality in the heterozygous state
Development (Cambridge), ISSN: 09501991
Jody Haigh; Hans-Peter Gerber; Napoleone Ferrara; Wagner
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Inhibitory Fc receptors modulate in vivo cytoxicity against tumor targets
Nature Medicine, ISSN: 10788956
Raphael A. Clynes; Terri L. Towers; Presta; Jeffrey V. Ravetch
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Peptide exosite inhibitors of factor VIIa as anticoagulants
Nature, ISSN: 00280836
Dennis; Charles Elgenbrot; Nicholas J. Skelton; Ultsch; Santell; Dwyer; Mark P. O'Connell; Lazarus
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Myoseverin, a microtubule-binding molecule with novel cellular effects
Nature Biotechnology, ISSN: 10870156
Gustavo R. Rosania; Young-Tae Chang; Omar Perez; Daniel P. Sutherlin; Helin Dong; David J. Lockhart; Peter G. Schultz
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Modulating pharmacokinetics of an anti-interleukin-8 F(ab')2 by amine- specific PEGylation with preserved bioactivity
International Journal of Pharmaceutics, ISSN: 03785173
Iphigenia Koumenis; Shahrokh; Leong; Vanessa Hsei; Laura DeForge; Gerardo Zapata
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Nasal epithelial permeation of thymotrinan (TP3) versus thymocartin (TP4): Competitive metabolism and self-enhancement
Pharmaceutical Research, ISSN: 07248741
M. Christiane Schmidt; Rubas; Hans P. Merkle
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Quantitative determination of SC-68328 in dog plasma using flow injection and tandem mass spectrometry
Journal of Mass Spectrometry, ISSN: 10765174
Ji Y. Zhang; Douglas M. Fast; Grant L. Schoenhard; Vinod K. Arora; Frank J. Belas; Ian A. Blair
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Lipopolysaccharide induces expression of APO2 ligand/TRAIL in human monocytes and macrophages
Scandinavian Journal of Immunology, ISSN: 03009475
Halaas; Vik; Ashkenazu; Espevik
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Interactions of HIV protease inhibitors with a human organic cation transporter in a mammalian expression system
Drug Metabolism and Disposition, ISSN: 00909556
Lei Zhang; Wenche Gorset; Carla Washington; Terrence F. Blaschke; Deanna L. Kroetz; Kathleen M. Giacomini
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