Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11651 - 11700 OF 15396 RESULTS

March 17, 2000

Highly organized spherical hosts that bind organic guests in aqueous solution with micromolar affinity: Microcalorimetry studies

Chemistry - A European Journal, ISSN: 09476539

Evgueni L. Piatnitski; Robert A. Flowers II; Deshayes

March 17, 2000

TrkA amino acids controlling specificity for nerve growth factor

Journal of Biological Chemistry, ISSN: 00219258

O'Connell; Hongo; Presta; Tsoulfas

March 14, 2000

A phase II trial of nerve growth factor for sensory neuropathy associated with HIV infection

Neurology, ISSN: 00283878

McArthur; Yiannoutsos; Simpson; Bruce T. Adornato; Singer; Hollander; Marra; Rubin; Cohen; Tucker; Navia; Schifitto; Katzenstein; Rask; Zaborski; Smith; Shriver; Millar; Clifford

March 13, 2000

Spinal motor axons and neural crest cells use different molecular guides for segmental migration through the rostral half-somite

Journal of Neurobiology, ISSN: 00223034

Koblar; Krull; Pasquale; McLennan; Peale; Cerretti; Bothwell

March 13, 2000

Treatment and outcome of myocardial infarction in hospitals with and without invasive capability

Journal of the American College of Cardiology, ISSN: 07351097

William J. Rogers; John G. Canto; Hal V. Barron; Joseph A Boscarino; David A. Shoultz; Nathan R. Every

March 10, 2000

Macromolecular inhibitors of HIV-1 protease. Characterization of designed heterodimers

Journal of Biological Chemistry, ISSN: 00219258

James E. Rozzelle; Deborah S. Dauber; Stephen Todd; Robert F. Kelley; Charles S. Craik

March 7, 2000

Recombinant human thrombopoietin attenuates carboplatin-induced severe thrombocytopenia and the need for platelet transfusions in patients with gynecologic cancer

Annals of Internal Medicine, ISSN: 00034819

Saroj Vadhan-Raj; Claire F. Verschraegen; Carlos Bueso-Ramos; Hal E. Broxmeyer; Andrzej P. Kudelka; Ralph S. Freedman; Creighton L. Edwards; David Gershenson; Jones Jr.; Ashby; John J. Kavanagh

March 3, 2000

Wnt signaling in oncogenesis and embryogenesis - A look outside the nucleus

Science, ISSN: 00368075

Mark Peifer; Paul G. Polakis

March 2, 2000

Toll genes and responsiveness to bacterial endotoxins [7] (multiple letters)

New England Journal of Medicine, ISSN: 00284793

James A. Thomas; Robert L. Modlin; Hans D. Brightbill; Godowski

March 1, 2000

Receptor-binding conformation of the 'ELR' motif of IL-8: X-ray structure of the L5C/H33C variant at 2.35 Å resolution

Proteins: Structure, Function and Bioinformatics, ISSN: 08873585

Nancy Gerber; Henry B. Lowman; Dean R. Artis; Eigenbrot

March 1, 2000

Do nerve growth factor-related mechanisms contribute to loss of cutaneous nociception in leprosy?

Pain, ISSN: 03043959

Paul Facer; Dawn Mann; Rajeev Mathur; Shubha Pandya; Uma Ladiwala; Bhim Singhal; Hongo; Sinicropi; Giorgio Terenghi; Anand

March 1, 2000

WISP-1 is a Wnt-1- and β-catenin-responsive oncogene

Genes and Development, ISSN: 08909369

Lifeng Xu; Ryan B. Corcoran; James W. Welsh; Diane Pennica; Arnold J. Levine

March 1, 2000

International union of pharmacology. XXII. Nomenclature for chemokine receptors

Pharmacological Reviews, ISSN: 00316997

Philip M. Murphy; Marco Baggiolini; Israel F. Charo; Hébert; Richard Horuk; Kouji Matsushima; Miller; Joost J. Oppenheim; Christine A. Power

March 1, 2000

Anesthesia induced retrograde amnesia is ameliorated by ephrin A5-IgG in mice: EphA receptor tyrosine kinases are involved in mammalian memory

Behavioural Brain Research, ISSN: 01664328

Gerlai; Alexander McNamara

March 1, 2000

Structure of the highly conserved HERC2 gene and of multiple partially duplicated paralogs in human

Genome Research, ISSN: 10889051

Yonggang Ji; Nancy A. Rebert; John M. Joslin; Michael J. Higgins; Roger A. Schultz; Robert D. Nicholls

February 21, 2000

Oncogenic Raf-1 disrupts epithelial tight junctions via downregulation of occludin

Journal of Cell Biology, ISSN: 00219525

Danxi Li; Mrsny

February 20, 2000

Comparison of three treatment options for single brain metastasis from lung cancer

International Journal of Cancer, ISSN: 00207136

Jun Itakura; Toshiyuki Ishiwata; Shen; Marko Kornmann; Murray Korc

February 18, 2000

High copy display of large proteins on phage for functional selections

Journal of Molecular Biology, ISSN: 00222836

Sachdev S. Sidhu; Gregory A. Weiss; James A. Wells

February 18, 2000

Convergent solutions to binding at a protein-protein interface

Science, ISSN: 00368075

Warren L. DeLano; Ultsch; De Vos; James A. Wells

February 15, 2000

Increased death receptor 5 expression by chemotherapeutic agents in human gliomas causes synergistic cytotoxicity with tumor necrosis factor- related apoptosis-inducing ligand in vitro and in vivo

Cancer Research, ISSN: 00085472

Motoo Nagane; Pan; Jessie J. Weddle; Vishva M. Dixit; Cavenee; Su Huang

February 9, 2000

Assessment of the myotoxicity of pharmaceutical buffers using an in vitro muscle model: Effect of pH, capacity, tonicity, and buffer type

Pharmaceutical Development and Technology, ISSN: 10837450

Jintana Napaporn; Maike Thomas; Kari A. Svetic; Shahrokh; Gayle A. Brazeau

February 7, 2000

Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling

Journal of Experimental Medicine, ISSN: 00221007

Tomasz Sosinowski; Akhilesh Pandey; Vishva M. Dixit; Arthur Weiss

February 4, 2000

Simian virus 40 large T antigen binds a novel Bcl-2 homology domain 3- containing proapoptosis protein in the cytoplasm

Journal of Biological Chemistry, ISSN: 00219258

Shih-Chong Tsai; Kishore B. S. Pasumarthi; Laura Pajak; Michael Franklin; Brian Patton; He Wang; William J. Henzel; Stults; Loren J. Field

February 1, 2000

Intracranial hemorrhage rates and effect of immediate beta-blocker use in patients with acute myocardial infarction treated with tissue plasminogen activator

American Journal of Cardiology, ISSN: 00029149

Hal V. Barron; Amy Chen Rundle; Joel M. Gore; Jerry H. Gurwitz; Jan Penney

February 1, 2000

High-dose recombinant interleukin-2 therapy in patients with metastatic melanoma: Long-term survival update

Cancer Journal from Scientific American, ISSN: 10814442

Michael B. Atkins; Lori Kunkel; Mario Sznol; Steven A. Rosenberg

February 1, 2000

Isolation and characterization of CRF-related diuretic hormones from the whitelined sphinx moth Hyles lineata

Insect Biochemistry and Molecular Biology, ISSN: 09651748

Kenji Furuya; Marilyn A. Harper; Kathleen M. Schegg; David A. Schooley

February 1, 2000

Transient focal cerebral ischemia induces sensorimotor deficits in mice

Behavioural Brain Research, ISSN: 01664328

Gerlai; Harold Thibodeaux; James T. Palmer; Menno Van Lookeren Campagne; Nicholas Van Bruggen

February 1, 2000

Long-term survival update for high-dose recombinant interleukin-2 in patients with renal cell carcinoma

Cancer Journal from Scientific American, ISSN: 10814442

Richard I. Fisher; Steven A. Rosenberg; Gwendolyn Fyfe

January 29, 2000

Brain-derived neurotrophic factor induces excitotoxic sensitivity in cultured embryonic rat spinal motor neurons through activation of the phosphatidylinositol 3-kinase pathway

Journal of Neurochemistry, ISSN: 00223042

Hugh J. L. Fryer; Daniel H. Wolf; Ronald J. Knox; Stephen M. Strittmatter; Diane Pennica; O'Leary; David S. Russell; Robert G. Kalb

January 25, 2000

Green fluorescent protein as a second selectable marker for selection of high producing clones from transfected CHO cells

Gene, ISSN: 03781119

Meng; Jie Liang; Wai Lee T. Wong; Chisholm

January 24, 2000

Cytokine-induced nuclear factor kappa B activation promotes the survival of developing neurons

Journal of Cell Biology, ISSN: 00219525

Gayle Middleton; Makoto Hamanoue; Yasushi Enokido; Sean Wyatt; Diane Pennica; Ellis Jaffray; Ronald T. Hay; Alun M. Davies

January 20, 2000

Coarse spray delivery to a localized region of the pulmonary airways for gene therapy

Human Gene Therapy, ISSN: 10430342

Cipolla; Gonda; Steven Shak; Kovesdi; Crystal; Sweeney

January 18, 2000

Cloning and characterization of IL-17B and IL-17C, two new members of the IL-17 cytokine family

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Hanzhong Li; Jian Chen; Arthur Huang; Stinson; Sherry Heldens; Foster; Patrick Dowd; Austin L. Gurney; William I. Wood

January 17, 2000

RGD mimetics containing a central hydantoin scaffold: α(v)β3 vs α(IIb)β3 selectivity requirements

Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X

Peyman; Volkmar Wehner; Knolle; Stilz; Breipohl; Karl-Heinz Scheunemann; Denis Carniato; Ruxer; Gourvest; Thomas Gadek; Bodary

January 15, 2000

Kistrin inhibits human smooth muscle cell interaction with fibrin

Thrombosis Research, ISSN: 00493848

Karen O Yee; Yuji Ikari; Bodary; Schwartz

January 15, 2000

A highly conserved enhancer in the Dlx5/Dlx6 intergenic region is the site of cross-regulatory interactions between Dlx genes in the embryonic forebrain

Journal of Neuroscience, ISSN: 02706474

Ted Zerucha; Thorsten Stühmer; Gary Hatch; Byung K. Park; Qiaoming Long; Guoying Yu; Adrianna Gambarotta; Joshua R. Schultz; John L. R. Rubenstein; Marc Ekker

January 11, 2000

Characterization of the binding interface between the E-domain of Staphylococcal protein A and an antibody Fv-fragment

Biochemistry, ISSN: 00062960

David Meininger; Mark Rance; Melissa A. Starovasnik; Wayne J. Fairbrother; Nicholas J. Skelton

January 1, 2000

Phage display in pharmaceutical biotechnology

Current Opinion in Biotechnology, ISSN: 09581669

Sachdev S. Sidhu

January 1, 2000

Pharmaceutical biotechnology the genomes are just the beginning: Editorial overview

Current Opinion in Biotechnology, ISSN: 09581669

Lawn; Lasky

January 1, 2000

Identification of paracaspases and metacaspases: Two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma

Molecular Cell, ISSN: 10972765

Anthony G. Uren; Karen M. O'Rourke; Aravind; Pisabarro; Somasekar Seshagiri; Eugene V. Koonin; Vishva M. Dixit

January 1, 2000

VEGF: An update on biological and therapeutic aspects

Current Opinion in Biotechnology, ISSN: 09581669

Napoleone Ferrara

January 1, 2000

Characterization of huJAM: Evidence for involvement in cell-cell contact and tight junction regulation

American Journal of Physiology - Cell Physiology, ISSN: 03636143

Tony W. Liang; Richard A. Demarco; Mrsny; Austin L. Gurney; Gray; Jeff Hooley; Holly L. Aaron; Arthur Huang; Toni Klassen; Daniel B. Tumas; Sherman Fong

January 1, 2000

Embryonic stem cells go dopaminergic

Neuron, ISSN: 08966273

Mary Hynes; Rosenthal

January 1, 2000

Pharmacokinetics and pharmacodynamics of sibrafiban, an orally administered GP IIb/IIIa antagonist, following coadministration of aspirin and heparin

Journal of Clinical Pharmacology, ISSN: 00912700

Reimann; Modi; Novotny

January 1, 2000

T-wave alternans and serious ventricular arrhythmias: A tale of two T-waves

Journal of the American College of Cardiology, ISSN: 07351097

Hal V. Barron

January 1, 2000

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5

Immunity, ISSN: 10747613

Frank C. Kischkel; David Lawrence; Anan Chuntharapai; Peter Schow; K.Jin Kim; Avi Ashkenazi

January 1, 2000

Cardiotrophin-1 reduces stress-induced heat shock protein production in cardiac myocytes

Cytokine, ISSN: 10434666

Julia Railson; Kevin Lawrence; Anastatis Stephanou; Bhawanjit K. Brar; Diane Pennica; David S. Latchman

January 1, 2000

A neutralizing monoclonal antibody specific for the dimer interface region of IL-8

Cytokine, ISSN: 10434666

Laura DeForge; Henry B. Lowman; Leong; Anan Chuntharapai; Jin Kim; Hébert

January 1, 2000

Amino acid analysis, using postcolumn ninhydrin detection, in a biotechnology laboratory.

Methods in Molecular Biology, ISSN: 10643745

Frank D. Macchi; Felicity J. Shen; Rodney Keck; Reed J. Harris

January 1, 2000

Nonparametric estimation of a periodic function

Biometrika, ISSN: 00063444

Peter Hall; Reimann; John Rice

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