Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11751 - 11800 OF 15396 RESULTS

Body mass index (BMI) in Turner syndrome before and during growth hormone (GH) therapy
International Journal of Obesity, ISSN: 03070565
Blackett; Amy Chen Rundle; James W. Frane; Sandra L. Blethen
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Effects of administration of a single dose of a humanized monoclonal antibody to CD11a on the immunobiology and clinical activity of psoriasis
Journal of the American Academy of Dermatology, ISSN: 01909622
Alice Gottlieb; James G. Krueger; Ross Bright; Mark Ling; Mark Lebwohl; Sewon Kang; Steve Feldman; Mary Spellman; Knut Wittkowski; Hans D. Ochs; Paula Jardieu; Bauer; Mark White; Russell L Dedrick; Marvin Garovoy
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Induction of an angiogenic phenotype in endometriotic stromal cell cultures by interleukin-1β
Molecular Human Reproduction, ISSN: 13609947
Dan I. Lebovic; Frauke Bentzien; Victor A. Chao; Evelyn N. Garrett; Meng; Robert N. Taylor
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Validation of excised bovine nasal mucosa as in vitro model to study drug transport and metabolic pathways in nasal epithelium
Journal of Pharmaceutical Sciences, ISSN: 00223549
M. Christiane Schmidt; Daniel Simmen; Monika Hilbe; Peter Boderke; Günter Ditzinger; Jürgen Sandow; Steffen Lang; Rubas; Hans P. Merkle
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Fast probabilistic analysis of sequence function using scoring matrices
Bioinformatics, ISSN: 13674803
Thomas D Wu; Craig G. Nevill-Manning; Douglas L. Brutlag
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Mammalian-cell-produced neurturin (NTN) is more potent than purified Escherichia coli-produced NTN
Experimental Neurology, ISSN: 00144886
Michael R. Hoane; Kamal D. Puri; Lei Xu; Paul F. Stabila; Hongmei Zhao; Amit G. Gulwadi; Phillips; Devaux; Mark D. Lindner; Weng Tao
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Estimation in a Cox proportional hazards cure model
Biometrics, ISSN: 0006341X
Sy; Jeremy M.G. Taylor
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Identification and regulation of receptor tyrosine kinases Rse and Mer and their ligand Gas6 in testicular somatic cells
Journal of Andrology, ISSN: 01963635
Michael C. W. Chan; Mather; Glynis McCray; Will M. Lee
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Use of phage display for the generation of human antibodies that neutralize factor IXa function
Blood Coagulation and Fibrinolysis, ISSN: 09575235
Shelley Suggett; Daniel Kirchhofer; Hass; Michael T. Lipari; Paul Moran; Nagel; Judice; Kurt A. Schroeder; Jeffrey Tom; Henry B. Lowman; Adams; Dan L. Eaton; Devaux
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Substrate-assisted catalysis: Molecular basis and biological significance
Protein Science, ISSN: 09618368
William Dall'Acqua; Paul J. Carter
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Web Alert. Apoptosis.
Chemistry and Biology, ISSN: 10745521
Eric W. Humke
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WECHE: A novel hematopoietic regulatory factor
Immunity, ISSN: 10747613
Osamu Ohneda; Kinuko Ohneda; Hisayuki Nomiyama; Zhong Zheng; Steven A. Gold; Fumio Arai; Takeshi Miyamoto; Bruce E. Taillon; Richard A. McIndoe; Richard A. Shimkets; Lewin; Toshio Suda; Lasky
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Targeting genes and proteins in the analysis of learning and memory: Caveats and future directions
Reviews in the Neurosciences, ISSN: 03341763
Gerlai
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Putting the pieces together: contribution of fluorescence polarization assays to small molecule lead optimization
Proceedings of SPIE - The International Society for Optical Engineering, ISSN: 0277786X
Keating; James C. Marsters Jr.; Beresini; Ladner; Kimberly Zioncheck; Clark; Arellano; Bodary
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The 2.0 Å structure of bovine interferon-γ; assessment of the structural differences between species
Acta Crystallographica Section D: Biological Crystallography, ISSN: 09074449
Michael Randal; Anthony A. Kossiakoff
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The glial cell line-derived neurotrophic factor family receptor components are differentially regulated within sensory neurons after nerve injury
Journal of Neuroscience, ISSN: 02706474
David L. H. Bennett; Timothy J. Boucher; Armanini; Kris Poulsen; Gregory J. Michael; John V. Priestley; Phillips; McMahon; David L. Shelton
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The importance of growth hormone replacement therapy for bone mass in young adults with growth hormone deficiency
Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X
Kenneth M. Attie
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A reversed-phase HPLC assay for plasminogen activators
Journal of Liquid Chromatography and Related Technologies, ISSN: 10826076
Yuan Xu; Cacia
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APO2L/TRAIL expression in human brain tumors
Acta Neuropathologica, ISSN: 00016322
Mitsutoshi Nakamura; Johannes Rieger; Michael Weller; Jin Kim; Paul Kleihues; Hiroko Ohgaki
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Growth hormone safety update from the National Cooperative Growth Study
Journal of Pediatric Endocrinology and Metabolism, ISSN: 0334018X
Thomas J. Maneatis; Joyce Baptista; Connelly; Sandra L. Blethen
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Role of the distal half of the c-Mpl intracellular domain in control of platelet production by thrombopoietin in vivo
Molecular and Cellular Biology, ISSN: 02707306
Shiuh-Ming Luoh; Stefanich; Gregg Solar; Hope Steinmetz; Michael T. Lipari; Tamara I. Pestina; Carl W. Jackson; Frederic J. De Sauvage
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Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancer
International Journal of Cancer, ISSN: 00207136
Jun Itakura; Toshiyuki Ishiwata; Shen; Marko Kornmann; Murray Korc
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Analysis of PTCH/SMO/SHH pathway genes in medulloblastoma
Genes Chromosomes and Cancer, ISSN: 10452257
Russell H. Zurawel; Cory Allen; Sharon Chiappa; Walter Cato; Jaclyn Biegel; Philip Cogen; Frederic J. De Sauvage; Corey Raffel
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Angiography of fluoresceinated anti-vascular endothelial growth factor antibody and dextrans in experimental choroidal neovascularization
Archives of Ophthalmology, ISSN: 00039950
Michael J. Tolentino; Deeba Husain; Panagiotis Theodosiadis; Evangelos S. Gragoudas; Edward Connolly; Jeanne Kahn; Cleland; Anthony P. Adamis; R. Andrew Cuthbertson; Joan W. Miller
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The seven-transmembrane receptor Smoothened cell-autonomously induces multiple ventral cell types
Nature Neuroscience, ISSN: 10976256
Mary Hynes; Weilan Ye; Kevin Wang; Donna Stone; Maximilien Murone; Frederic J. De Sauvage; Rosenthal
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The nucleoskeleton: Go EAST, young man
Nature Cell Biology, ISSN: 14657392
Lasky
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Clonidine for smoking cessation.
Cochrane database of systematic reviews (Online : Update Software), ISSN: 1469493X
Steven G. Gourlay; Stead; Neal L. Benowitz
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Gene expression profiling in an in vitro model of angiogenesis
American Journal of Pathology, ISSN: 00029440
Jeanne Kahn; Fuad Mehraban; Gladys S. Ingle; Xiaohua Xin; Juliet E. Bryant; Gordon A. Vehar; Schoenfeld; Grimaldi; Franklin V. Peale Jr.; Aparna Draksharapu; Lewin; Mary E. Gerritsen
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Toll-like receptor 2-mediated NF-κB activation requires a Rac I-dependent pathway
Nature Immunology, ISSN: 15292908
Laurence Arbibe; Jean-Paul Mira; Nicole Teusch; Lois Kline; Mausumee Guha; Nigel Mackman; Godowski; Richard J. Ulevitch; Ulla G. Knaus
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Pharmacokinetics and pharmacodynamics of tenecteplase: Results from a phase II study in patients with acute myocardial infarction
Journal of Clinical Pharmacology, ISSN: 00912700
Modi; Fox; Fong-Wong Clow; Tanswell; Christopher P. Cannon; Frans Van De Werf; Eugene Braunwald
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Mice lacking α-synuclein display functional deficits in the nigrostriatal dopamine system
Neuron, ISSN: 08966273
Asa Abeliovich; Yvonne Schmitz; Isabel Fariñas; Choi-Lundberg; Ho; Pablo E. Castillo; Natasha Shinsky; Jose Manuel Garcia-Verdugo; Armanini; Anne Ryan; Mary Hynes; Phillips; David Sulzer; Rosenthal
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Purification of yeast mitochondrial Hsp60.
Methods in Molecular Biology, ISSN: 10643745
Yves Dubaquié; Renate Looser; Sabine Rospert
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Drug information in industry versus academia: A pharmacy resident's perspective of a sample case
Therapeutic Innovation and Regulatory Science, ISSN: 21684790
Graham; David A. Graves; Barry Grobman; Gary M. Mccart; Candy Tsourounis
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Comparison of the rates of deamidation, diketopiperazine formation, and oxidation in recombinant human vascular endothelial growth factor and model peptides
AAPS PharmSci, ISSN: 15221059
Chimanlall Goolcharran; Andrew J.S. Jones; Ronald T. Borchardt; Cleland; Rodney Keck
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Characterization of huJAM: Evidence for involvement in cell-cell contact and tight junction regulation
American Journal of Physiology - Cell Physiology, ISSN: 03636143
Tony W. Liang; Richard A. Demarco; Mrsny; Austin L. Gurney; Gray; Jeff Hooley; Holly L. Aaron; Arthur Huang; Toni Klassen; Daniel B. Tumas; Fong
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Expression of activated CDC42 induces T cell apoptosis in thymus and peripheral lymph organs via different pathways
Oncogene, ISSN: 09509232
Songqing Na; Baiyong Li; Iqbal S. Grewal; Hervé Enslen; Roger J. Davis; Jeffrey H. Hanke; Richard A. Flavell
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Treatment of allergic asthma with monoclonal anti-IgE antibody
New England Journal of Medicine, ISSN: 00284793
Henry Milgrom; Robert B. Fick Jr.; John Q. Su; Reimann; Robert K. Bush; Marc Watrous; W. James Metzger
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Baculovirus-based genetic screen for antiapoptotic genes identifies a novel IAP
Journal of Biological Chemistry, ISSN: 00219258
Somasekar Seshagiri; Domagoj Vucic; James Lee; Vishva M. Dixit
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Functional interaction between Gα(z) and Rap1GAP suggests a novel form of cellular cross-talk
Journal of Biological Chemistry, ISSN: 00219258
Jingwei Meng; Jennifer L. Glick; Paul G. Polakis; Patrick J. Casey
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Autosomal recessive chronic granulomatous disease caused by novel mutations in NCF-2, the gene encoding the p67-phox component of phagocyte NADPH oxidase
Human Genetics, ISSN: 03406717
Noack; Julie Rae; Andrew R. Cross; José Muñoz; Siham Salmen; José A. Mendoza; Nineth Rossi; John T. Curnutte; Heyworth
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Overexpression of thioredoxin h leads to enhanced activity of starch debranching enzyme (pullulanase) in barley grain
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Myeong-Je Cho; Joshua H. Wong; Corina Marx; Jiang; Peggy G. Lemaux; Bob B. Buchanan
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Development of bivalent (B/E) vaccines able to neutralize CCR5-dependent viruses from the United States and Thailand
Virology, ISSN: 00426822
Berman; Wei Huang; Riddle; Gray; Wrin; Vennari; Johnson; Michael Klaussen; Prashad; Christiane Köhne; Christina De Wit; Timothy Gregory
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Chapter 3.1.10 Targeting genes associated with mammalian behavior: past mistakes and future solutions
Techniques in the Behavioral and Neural Sciences, ISSN: 09210709
Gerlai
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Preface. Behavioral neurogenetics: the new synthesis
Techniques in the Behavioral and Neural Sciences, ISSN: 09210709
Wim E. Crusio; Gerlai
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Characterization of the human Suppressor of fused, a negative regulator of the zinc-finger transcription factor Gli
Journal of Cell Science, ISSN: 00219533
Donna Stone; Maximilien Murone; Shiuh-Ming Luoh; Weilan Ye; Armanini; Austin L. Gurney; Phillips; Brush; Goddard; Frederic J. De Sauvage; Rosenthal
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Clinical applications of angiogenic growth factors and their inhibitors
Nature Medicine, ISSN: 10788956
Napoleone Ferrara; Kari Alitalo
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Chapter 3.2.7 Protein targeting in the functional analysis of EphA receptors: the use of immunoadhesins
Techniques in the Behavioral and Neural Sciences, ISSN: 09210709
Gerlai; Natasha Shinsky; Shih; P. Mickey Williams; Jane Winer; Armanini; Paul Moran; Cairns; Winslow; Gao; Phillips
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Activation of microglia reveals a non-proteolytic cytokine function for tissue plasminogen activator in the central nervous system
Journal of Cell Science, ISSN: 00219533
Andrew D. Rogove; Chia-Jen Siao; Keyt; Sidney Strickland; Stella E. Tsirka
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Recovery of severe sciatica
Spine, ISSN: 03622436
Federico Balagué; Margareta Nordin; Ali Sheikhzadeh; Anne-Catherine Echegoyen; Helena Brisby; Henri Marcel Hoogewoud; Pam Fredman; Mary Louise Skovron
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Chapter 2.2.4 Application of real-time RT-PCR for quantification of gene expression
Techniques in the Behavioral and Neural Sciences, ISSN: 09210709
Jane Winer; Natasha Shinsky; Gerlai; P. Mickey Williams
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