Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 11851 - 11900 OF 15396 RESULTS

Caspase activation: The induced-proximity model
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Guy S. Salvesen; Vishva M. Dixit
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Molecular and biological properties of vascular endothelial growth factor
Journal of Molecular Medicine, ISSN: 09462716
Napoleone Ferrara
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CD40-CD40 ligand costimulation is required for generating antiviral CD4 T cell responses but is dispensable for CD8 T cell responses
Journal of Immunology, ISSN: 00221767
Jason K. Whitmire; Richard A. Flavell; Iqbal S. Grewal; Christian P. Larsen; Thomas C. Pearson; Rafi Ahmed
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The use of a porous graphitic carbon column for desalting hydrophilic peptides prior to matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
Analytical Biochemistry, ISSN: 00032697
Chin; Damon I. Papac
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The nonclassical class I molecule CD1d associates with the novel CD8 ligand gp180 on intestinal epithelial cells
Journal of Biological Chemistry, ISSN: 00219258
Nicola A. Campbell; Hyun S. Kim; Blumberg; Lloyd Mayer
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Analyzing mixtures of amino acids and carbohydrates using bi-modal integrated amperometric detection
Journal of Chromatography B: Biomedical Sciences and Applications, ISSN: 13872273
Petr Jandik; Alan P. Clarke; Nebojsa Avdalovic; Dana C. Andersen; Cacia
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Crystal structure of nerve growth factor in complex with the ligand- binding domain of the TrkA receptor
Nature, ISSN: 00280836
Christian Wlesmann; Ultsch; Bass; De Vos
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Overview of the trastuzumab (Herceptin) anti-HER2 monoclonal antibody clinical program in HER2-overexpressing metastatic breast cancer
Seminars in Oncology, ISSN: 00937754
Steven Shak
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Nonclinical studies addressing the mechanism of action of trastuzumab (Herceptin)
Seminars in Oncology, ISSN: 00937754
Mark X. Sliwkowski; Julie A. Lofgren; Gail D. Lewis; Hotaling; Brian M. Fendly; Judy Fox
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New cases of pseudomonas aeruginosa: Treatment and outcomes
Pediatric Pulmonology, ISSN: 87556863
Wagener; Butler; Harvey R. Rabin; Warren E. Regelmann; Charles A. Johnson
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Multicolor immunofluorescence and flow cytometry utilizing cascade blue to purify murine hematopoietic stem cells from fetal liver and bone marrow
Communications in Clinical Cytometry, ISSN: 01964763
Christopher J. Donahue; Christopher Fennie; Ricardo Villacorta; Hank La; Lasky; Osamu Ohneda
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A novel mutation in the CYBB gene resulting in an unexpected pattern of exon skipping and chronic granulomatous disease
Biochimica et Biophysica Acta - Molecular Basis of Disease, ISSN: 09254439
Noack; Heyworth; John T. Curnutte; Julie Rae; Andrew R. Cross
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Genetic variation in susceptibility to endocrine disruption by estrogen in mice
Science, ISSN: 00368075
Jimmy L. Spearow; Paul Doemeny; Robyn Sera; Rachael Leffler; Marylynn Barkley
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Phosphopeptide analysis by on-line immobilized metal-ion affinity chromatography-capillary electrophoresis-electrospray ionization mass spectrometry
Journal of Chromatography A, ISSN: 00219673
Ping Cao; Stults
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Use of acidic and basic pH and calcium ion addition in the capillary zone electrophoretic characterization of recombinant human deoxyribonuclease, a complex phosphoglycoprotein
Journal of Chromatography A, ISSN: 00219673
Chantal Felten; Quan; Chen; Eleanor Canova-Davis; McNerney; Wolfgang K. Goetzinger; Karger
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Selection for improved subtiligases by phage display
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Shane Atwell; James A. Wells
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Distribution and function of the adhesion molecule BEN during rat development
Developmental Biology, ISSN: 00121606
Jean-Philippe Stephan; Bald; Penelope E. Roberts; James Lee; Qimin Gu; Mather
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Activation of human neutrophil NADPH oxidase by phosphatidic acid or diacylglycerol in a cell-free system. Activity of diacylglycerol is dependent on its conversion to phosphatidic acid
Journal of Biological Chemistry, ISSN: 00219258
Erickson; Paola Langel-Peveri; Alexis E. Traynor-Kaplan; Heyworth; John T. Curnutte
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Endothelial-monocyte activating polypeptide II, a novel antitumor cytokine that suppresses primary and metastatic tumor growth and induces apoptosis in growing endothelial cells
Journal of Experimental Medicine, ISSN: 00221007
Margaret A. Schwarz; Jessica Kandel; Jerold Brett; Jun Li; Joanne Hayward; Roderich E. Schwarz; Olivier Chappey; Jean-Luc Wautier; John Chabot; Paul Lo Gerfo; David Stern
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Constitutive expression of VEGF, VEGFR-1, and VEGFR-2 in normal eyes
Investigative Ophthalmology and Visual Science, ISSN: 01460404
Ivana K. Kim; Anne Ryan; Richard Rohan; Shiro Amano; Stephanie Agular; Joan W. Miller; Anthony P. Adamis
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Anaerobic degradation of ethylbenzene and toluene in denitrifying strain EbN1 proceeds via independent substrate-induced pathways
Journal of Molecular Microbiology and Biotechnology, ISSN: 14641801
Kathleen M. Champion; Karsten Zengler; Ralf Rabus
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Gene expression analysis by transcript profiling coupled to a gene database query
Nature Biotechnology, ISSN: 10870156
Richard A. Shimkets; David G Lowe; Julie Tsu-Ning Tai; Sehl; Hongkui Jin; Renhui Yang; Paul F. Predki; Bonnie E. G. Rothberg; Michael T. Murtha; Matthew E. Roth; Suresh G. Shenoy; Andreas Windemuth; John W. Simpson; Jan F. Simons; Michael P. Daley; Steven A. Gold; Michael P. McKenna; Kenneth J. Hillan; Gregory T. Went; Jonathan M. Rothberg
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Diagnosis and Treatment of Equine Cushing's Disease
Compendium on Continuing Education for the Practicing Veterinarian, ISSN: 01931903
Michel Levy; Janice E. Sojka; Noel Dybdal
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Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors
Science, ISSN: 00368075
Hans D. Brightbill; Daniel H. Libraty; Stephan R. Krutzik; Ruey-Bing Yang; John T. Belisle; Joshua R. Bleharski; Michael Maitland; Michael V. Norgard; Scott E. Plevy; Stephen T. Smale; Patrick J. Brennan; Bloom; Godowski; Robert L. Modlin
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Cell activation and apoptosis by bacterial lipoproteins through Toll- like receptor-2
Science, ISSN: 00368075
Antonios O. Aliprantis; Ruey-Bing Yang; Melanie R Mark; Shelly Suggett; Devaux; Justin D. Radolf; Gary R. Klimpel; Godowski; Arturo Zychlinsky
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Multiple Ras effector pathways contribute to G1 cell cycle progression
Journal of Biological Chemistry, ISSN: 00219258
Hendrik Gille; Julian Downward
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A convenient microscale colorimetric method for terminal galactose on immunoglobulins
Biochemical and Biophysical Research Communications, ISSN: 0006291X
T. Shantha Raju; Namita Nayak; Briggs; O'Connor; Laura Lerner
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Hemostatic effects of 1 mg daily warfarin on post CABG patients
Journal of Thrombosis and Thrombolysis, ISSN: 09295305
Jeanine M. Walenga; Debra Hoppensteadt; Roque Pifarré; Michael D. Cressman; Donald B. Hunninghake; Fox; Michael L. Terrin; Jeffrey L. Probstfield
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Stoichiometry of the interaction between the major histocompatibility- complex-related Fc receptor and its Fc ligand
Biochemistry, ISSN: 00062960
Luis M. Sánchez; David M. Penny; Pamela J. Bjorkman
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Transgene expression in the guinea pig cochlea mediated by a lentivirus- derived gene transfer vector
Human Gene Therapy, ISSN: 10430342
Jay J. Han; Anand N. Mhatre; Michael Wareing; Robert Pettis; Gao; Romain N. Zufferey; Didier Trono; Anil K. Lalwani
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Real-time control of antibody loading during protein A affinity chromatography using an on-line assay
Journal of Chromatography A, ISSN: 00219673
Fahrner; Gregory S. Blank
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The mechanism of activation of NADPH oxidase in the cell-free system: The activation process is primarily catalytic and not through the formation of a stoichiometric complex
Biochemical Journal, ISSN: 02646021
Andrew R. Cross; Erickson; John T. Curnutte
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Signaling events induced by lipopolysaccharide-activated Toll-like receptor 2
Journal of Immunology, ISSN: 00221767
Ruey-Bing Yang; Melanie R Mark; Austin L. Gurney; Godowski
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Disruption of a retinal guanylyl cyclase gene leads to cone-specific dystrophy and paradoxical rod behavior
Journal of Neuroscience, ISSN: 02706474
Ruey-Bing Yang; Susan W. Robinson; Wei-Hong Xiong; King-Wai Yau; David G. Birch; Garbers
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Determination of residues involved in ligand binding and signal transmission in the human IFN-α receptor 2
Journal of Immunology, ISSN: 00221767
Anan Chuntharapai; Gibbs; Lu; Ow; Scot A. Marsters; Avi Ashkenazi; De Vos; K.Jin Kim
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Pex22p of Pichia pastoris, essential for peroxisomal matrix protein import, anchors the ubiquitin-conjugating enzyme, Pex4p, on the peroxisomal membrane
Journal of Cell Biology, ISSN: 00219525
Antonius Koller; William B. Snyder; Klaas Nico Faber; Thibaut J. Wenzel; Linda Rangell; Gilbert-Andre Keller; Suresh Subramani
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Predictors and timing of adverse experiences during transdermal nicotine therapy
Drug Safety, ISSN: 01145916
Steven G. Gourlay; Andrew Forbes; Tracey Marriner; John J. McNeil
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Identification of amino acids that modulate mannose phosphorylation of mouse DNase I, a secretory glycoprotein
Journal of Biological Chemistry, ISSN: 00219258
Atsushi Nishikawa; Akash Nanda; Walter Gregory; John Frenz; Stuart Kornfeld
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Crystal structures of the neurotrophin-binding domain of TrkA, TrkB and TrkC
Journal of Molecular Biology, ISSN: 00222836
Ultsch; Wiesmann; Laura C. Simmons; Jill Henrich; Yang; Dorothea Reilly; Bass; De Vos
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High-performance tangential flow filtration using charged membranes
Journal of Membrane Science, ISSN: 03767388
Robert Van Reis; Brake; Charkoudian; Burns; Andrew Zydney
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Investigation of protein-surfactant interactions by analytical ultracentrifugation and electron paramagnetic resonance: The use of recombinant human tissue factor as an example
Pharmaceutical Research, ISSN: 07248741
LaToya S. Jones; Cipolla; Jun Liu; Steven J. Shire; Theodore W. Randolph
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Cardiotrophin-1 attenuates endotoxin-induced acute lung injury
Journal of Surgical Research, ISSN: 00224804
Edward J. Pulido; Brian D. Shames; Diane Pennica; O'Leary; Denis D. Bensard; Brian S. Cain; Robert C. McIntyre Jr.
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Brain-derived neurotrophic factor modulates nociceptive sensory inputs and NMDA-evoked responses in the rat spinal cord
Journal of Neuroscience, ISSN: 02706474
Kerr; Bradbury; David L. H. Bennett; Trivedi; Dassan; French; David L. Shelton; McMahon; Stephen W.N. Thompson
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Zebrafish genetic map with 2000 microsatellite markers
Genomics, ISSN: 08887543
Nobuyoshi Shimoda; Ela W. Knapik; John Ziniti; Chäng Sim; Erika Yamada; Stacy Kaplan; Donald Jackson; Frederic J. De Sauvage; Howard Jacob; Mark C. Fishman
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RIP3, a novel apoptosis-inducing kinase
Journal of Biological Chemistry, ISSN: 00219258
Xiaoqing Sun; Lee James; Tony A. Navas; Daryl T. Baldwin; Stewart; Vishva M. Dixit
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The toll of innate immunity on microbial pathogens
New England Journal of Medicine, ISSN: 00284793
Robert L. Modlin; Hans D. Brightbill; Godowski
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Lack of developmental neurotoxicity of MN rgp120/HIV-1 administered subcutaneously to neonatal rats
Toxicological Sciences, ISSN: 10966080
Bussiere; Laurel M. Hardy; Peterson; John A. Foss; Robert H. Garman; Alan M. Hoberman; Mildred S. Christian
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A low-volume, short-path length dynamic light scattering sample cell for highly turbid suspensions
Analytical Biochemistry, ISSN: 00032697
Thomas W. Patapoff; Travis H. Tani; Cromwell
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The effect of O-fucosylation on the first EGF-like domain from human blood coagulation factor VII
Biochemistry, ISSN: 00062960
Yung-Hsiang Kao; Geoffrey F. Lee; Yang Wang; Melissa A. Starovasnik; Robert F. Kelley; Spellman; Laura Lerner
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Signalling by the RET receptor tyrosine kinase and its role in the development of the mammalian enteric nervous system
Development (Cambridge), ISSN: 09501991
Stavros Taraviras; Camelia V. Marcos-Gutierrez; Pascale Durbec; Harsha Jani; Maria Grigoriou; Madhu Sukumaran; Li-Chong Wang; Mary Hynes; Geoffrey Raisman; Vassilis Pachnis
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