Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12251 - 12300 OF 15396 RESULTS

Interferon gamma-1b compared with placebo in metastatic renal-cell carcinoma
New England Journal of Medicine, ISSN: 00284793
Martin E. Gleave; Mostafa Elhilali; Yves Fradet; Ian Davis; Peter Venner; Fred Saad; Laurence H. Klotz; Moore; Virginia Paton; Alex Bajamonde; David Bell; Scott Ernst; Ernest Ramsey; Joe Chin; Alvaro Morales; Heidi Martins; Corsee Sanders
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Stability of alkoxycarbonylamidine prodrugs
Pharmaceutical Research, ISSN: 07248741
Shahrokh; Eric Lee; Alan G. Olivero; Regina A. Matamores; Kirk D. Robarge; Arthur Lee; Kenneth J. Weise; Brent Blackburn; Powell
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Recognition properties of a sequence-specific DNA binding antibody
Biochemistry, ISSN: 00062960
James F. LeBlanc; Kathryn E. McLane; Paul W. H. I. Parren; Dennis R. Burton; Peter Ghazal
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Identification of a ligand for the death-domain-containing receptor Apo3
Current Biology, ISSN: 09609822
Scot A. Marsters; James P. Sheridan; Pitti; Brush; Goddard; Avi Ashkenazi
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Calpain inhibitors, but not caspase inhibitors, prevent actin proteolysis and DNA fragmentation during apoptosis
Journal of Cell Science, ISSN: 00219533
Pascal G. Villa; William J. Henzel; Monique Sensenbrenner; Christopher E. Henderson; Brigitte Pettmann
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Cranial computed tomography interpretation in acute stroke: Physician accuracy in determining eligibility for thrombolytic therapy
JAMA - Journal of the American Medical Association, ISSN: 00987484
David L. Schriger; Mary Kalafut; Sidney Starkman; Michelle Krueger; Jeffrey L. Saver
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Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity
Journal of Molecular Biology, ISSN: 00222836
Clackson; Ultsch; James A. Wells; De Vos
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Characterization of V3 loop-Pseudomonas exotoxin chimeras: Candidate vaccines for human immunodeficiency virus-1
Journal of Biological Chemistry, ISSN: 00219258
David FitzGerald; Charlotte M. Fryling; Marian McKee; Vennari; Wrin; Cromwell; Daugherty; Mrsny
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A p55 TNF receptor immunoadhesin prevents T cell-mediated intestinal injury by inhibiting matrix metalloproteinase production
Journal of Immunology, ISSN: 00221767
Sylvia L. F. Pender; John M. E. Fell; Steven M. Chamow; Avi Ashkenazi; Thomas T. MacDonald
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Vascular endothelial growth factor is essential for corpus luteum angiogenesis
Nature Medicine, ISSN: 10788956
Napoleone Ferrara; Helen Chen; Terri Davis-Smyth; Hans-Peter Gerber; Thuy-Nhung Nguyen; Peers; Chisholm; Kenneth J. Hillan; Ralph H. Schwall
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A large-scale process to produce microencapsulated proteins
Pharmaceutical Research, ISSN: 07248741
Paul Herbert; Keith Murphy; OluFunmi Johnson; Nan Dong; Warren Jaworowicz; Mark A. Tracy; Cleland; Putney
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An integrated approach to proteome analysis: Identification of proteins associated with cardiac hypertrophy
Analytical Biochemistry, ISSN: 00032697
David Arnott; Kathy L. O'Connell; King; Stults
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Activation of caspases triggered by cytochrome c in vitro
FEBS Letters, ISSN: 00145793
Guoha Pan; Eric W. Humke; Vishva M. Dixit
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TNF is a potent anti-inflammatory cytokine in autoimmune-mediated demyelination
Nature Medicine, ISSN: 10788956
Junliang Liu; Michael W. Marino; Grace H.W. Wong; Dianne Grail; Ashley Dunn; Jayaram Bettadapura; Anthony J. Slavin; Lloyd Old; Claude C.A. Bernard
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Purification and characterization of a GDP-fucose:polypeptide fucosyltransferase from Chinese hamster ovary cells
Journal of Biological Chemistry, ISSN: 00219258
Yang Wang; Spellman
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Serum thrombopoietin levels in Kawasaki disease
British Journal of Haematology, ISSN: 00071048
Nobuyuki Mlura; Masaru Terai; Meng; Takeyuki Sato; Hlroo Nlimi
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Overexpression of cardiotrophin-1 and gp130 during experimental acute Chagasic cardiomyopathy
Immunology Letters, ISSN: 01652478
Bysani Chandrasekar; Peter C. Melby; Diane Pennica; Gregory L. Freeman
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Neutralizing anti-vascular endothelial growth factor antibody completely inhibits angiogenesis and growth of human prostate carcinoma micro tumors in vivo
Prostate, ISSN: 02704137
Per Borgström; Mario A. Bourdon; Kenneth J. Hillan; Sriramarao; Napoleone Ferrara
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Use of reperfusion therapy for acute myocardial infarction in the United States: Data from the National Registry of Myocardial Infarction 2
Circulation, ISSN: 00097322
Hal V. Barron; Laura J. Bowlby; Timothy J. Breen; William J. Rogers; John G. Canto; Yuan Zhang; Alan J. Tiefenbrunn; W.Douglas Weaver
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Receptor-specific ligands distinguish natriuretic peptide receptors-A and -C in primate tissues
Molecular and Cellular Biochemistry, ISSN: 03008177
Sehl; Jeffrey Tom; David A. Oare; David G Lowe
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Binding and regulation of thrombopoietin to human megakaryocytes
British Journal of Haematology, ISSN: 00071048
Takeyuki Sato; Akira Fuse; Hiroo Niimi; Fielder; Hava Avraham
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Validation of a capillary isoelectric focusing method for the recombinant monoclonal antibody C2B8
Journal of Chromatography A, ISSN: 00219673
Glenn Hunt; Hotaling; Chen
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The disruption of heregulin, ErbB2, and ErbB3 genes leads to cardiac and neural abnormalities: Roles in development and adulthood
FASEB Journal, ISSN: 08926638
Sharon Erickson
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Immunoliposomes containing antibodies to costimulatory molecules as adjuvants for HIV subunit vaccines
AIDS Research and Human Retroviruses, ISSN: 08892229
Bulent Ozpolat; Xiao-Mei Rao; Powell; Lawrence B. Lachman
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CARP expression in two rat cardiac hypertrophy models
FASEB Journal, ISSN: 08926638
Michael Lew; Lesley A. Brown; Sehl; Kenneth J. Hillan; David G Lowe
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Elevated expression of KDR receptor in response to Vascular Endothelial Growth Factor (VEGF) treatment
FASEB Journal, ISSN: 08926638
Shen; David Y. Lee; Hans-Peter Gerber; Napoleone Ferrara; Keyt; Zioncheck
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Computational learning reveals coiled coil-like motifs in histidine kinase linker domains
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Mona Singh; Bonnie Berger; Peter S. Kim; James M. Berger; Andrea G Cochran
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Overexpression of Escherichia coli oxidoreductases increases recombinant insulin-like growth factor-I accumulation
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
John C. Joly; Leung; James R. Swartz
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Caspase-9, Bcl-X(L), and Apaf-1 form a ternary complex
Journal of Biological Chemistry, ISSN: 00219258
Pan; Karen M. O'Rourke; Vishva M. Dixit
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High resolution mapping of the binding site of TrkA for nerve growth factor and TrkC for neurotrophin-3 on the second immunoglobulin-like domain of the TrK receptors
Journal of Biological Chemistry, ISSN: 00219258
Urfer; Tsoulfas; O'Connell; Hongo; Wei Zhao; Presta
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Tyrosine phosphorylation regulates the SH3-mediated binding of the Wiskott-Aldrich syndrome protein to PSTPIP, a cytoskeletal-associated protein
Journal of Biological Chemistry, ISSN: 00219258
Yan Wu; Spencer; Lasky
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Ammonium ion and glucosamine dependent increases of oligosaccharide complexity in recombinant glycoproteins secreted from cultivated BHK-21 cells
Biotechnology and Bioengineering, ISSN: 00063592
Martin Gawlitzek; Ulrich Valley; Roland Wagner
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Prebeta-1 HDL in plasma of normolipidemic individuals: Influences of plasma lipoproteins, age, and gender
Journal of Lipid Research, ISSN: 00222275
Patricia M. O'Connor; Zysow; Schoenhaus; Ishida; Kunitake; Naya-Vigne; Duchateau; Redberg; Susan J. Spencer; Mark; Mazur; Heilbron; Jaffe; Malloy; Kane
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Establishment of conditionally immortalized rat utricular epithelial cell lines using a retrovirus-mediated gene transfer technique
Hearing Research, ISSN: 03785955
Zheng; Lewis; Gao
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Pharmacokinetics and pharmacodynamics of recombinant tissue-type plasminogen activator following intravenous administration in rabbits: A comparison of three dosing regimens
Biopharmaceutics and Drug Disposition, ISSN: 01422782
Stephen M. Eppler; Tauri D. Senn; Ellen Gilkerson; Modi
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The orphan receptor CRF2-4 is an essential subunit of the interleukin 10 receptor
Journal of Experimental Medicine, ISSN: 00221007
Spencer; Francesco Di Marco; Jeff Hooley; Sharon Pitts-Meek; Michele Bauer; Anne Ryan; Bernard Sordat; Gibbs; Michel Aguet
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Structure-function study of the extracellular domain of the human IFN- α receptor (hIFNAR1) using blocking monoclonal antibodies: The role of domains 1 and 2
Journal of Immunology, ISSN: 00221767
Lu; Anan Chuntharapai; Joanne T. Beck; Bass; Ow; De Vos; Gibbs; K.Jin Kim
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Structure-function study of the extracellular domain of the human IFN- α receptor (hIFNAR1) using blocking monoclonal antibodies: The role of domains 1 and 2
Journal of Immunology, ISSN: 00221767
Lu; Anan Chuntharapai; Joanne Beck; Bass; Ow; De Vos; Gibbs; K.Jin Kim
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A novel soluble tissue factor variant with an altered factor VIIa binding interface
Journal of Biological Chemistry, ISSN: 00219258
Geoffrey F. Lee; Robert F. Kelley
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Mapping the charged residues in the second immunoglobulin-like domain of the vascular endothelial growth factor/placenta growth factor receptor Flt-1 required for binding and structural stability
Journal of Biological Chemistry, ISSN: 00219258
Terri Davis-Smyth; Presta; Napoleone Ferrara
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Pervasive conformational fluctuations on microsecond time scales in a fibronectin type III domain
Nature Structural Biology, ISSN: 10728368
Mikael Akke; Jun Liu; John Cavanagh; Harold P. Erickson; Arthur G. Palmer III
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Solution structure of the fourth metal-binding domain from the Menkes copper-transporting ATPase
Nature Structural Biology, ISSN: 10728368
Jane Gitschier; Moffat; Dorothea Reilly; William I. Wood; Wayne J. Fairbrother
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Potentiated angiogenic effect of scatter factor/hepatocyte growth factor via induction of vascular endothelial growth factor: The case for paracrine amplification of angiogenesis
Circulation, ISSN: 00097322
Eric Van Belle; Bernhard Witzenbichler; Donghui Chen; Marcy Silver; Ling Chang; Ralph H. Schwall; Jeffrey M. Isner
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Randomized trial of an oral platelet glycoprotein IIb/IIIa antagonist, sibrafiban, in patients after an acute coronary syndrome: Results of the TIMI 12 trial
Circulation, ISSN: 00097322
Christopher P. Cannon; Carolyn H. McCabe; Steven Borzak; Timothy D. Henry; Marc D. Tischler; Hiltrud S. Mueller; Robert Feldman; Sebastian T. Palmeri; Kenneth A. Ault; Scott A. Hamilton; Joel M. Rothman; Novotny; Eugene Braunwald
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Randomized trial of an oral platelet glycoprotein IIb/IIIa antagonist, sibrafiban, in patients after an acute coronary syndrome: Results of the TIMI 12 trial
Circulation, ISSN: 00097322
Christopher P. Cannon; Carolyn H. McCabe; Steven Borzak; Timothy D. Henry; Marc D. Tischler; Hiltrud S. Mueller; Robert Feldman; Sebastian T. Palmeri; Kenneth A. Ault; Scott Hamilton; Joel M. Rothman; Novotny; Eugene Braunwald
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Synergistic effects of Schwann- and muscle-derived factors on motoneuron survival involve GDNF and cardiotrophin-1 (CT-1)
Journal of Neuroscience, ISSN: 02706474
Vilma Arce; Richard A. Pollock; Jean-Marc Philippe; Diane Pennica; Christopher E. Henderson; Odile Delapeyrière
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Cytokines promote the survival of mouse cranial sensory neurones at different developmental stages
European Journal of Neuroscience, ISSN: 0953816X
Antony Horton; Perry F. Bartlett; Diane Pennica; Alun M. Davies
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An oligopeptide transporter is expressed at high levels in the pancreatic carcinoma cell lines AsPc-1 and Capan-2
Cancer Research, ISSN: 00085472
Deborah E. Gonzalez; Kuang-Ming Y. Covitz; Wolfgang Sadée; Mrsny
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Effect of smaller droplet size of dornase alfa on lung function in mild cystic fibrosis
Pediatric Pulmonology, ISSN: 87556863
David E. Geller; Howard Eigen; Stanley B. Fiel; Clark; André P. Lamarre; Charles A. Johnson; Michael W. Konstan
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Disruption of a putative SH3 domain and the proline-rich motifs in the 53-kDa substrate of the insulin receptor kinase does not alter its subcellular localization or ability to serve as a substrate
Journal of Cellular Biochemistry, ISSN: 07302312
Tammie C. Yeh; Wenlu Li; Gilbert-Andre Keller; Richard A. Roth
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