Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12301 - 12350 OF 15396 RESULTS

January 30, 1998

An induced proximity model for caspase-8 activation

Journal of Biological Chemistry, ISSN: 00219258

Marta Muzio; Brent R. Stockwell; Henning R. Stennicke; Guy S. Salvesen; Vishva M. Dixit

January 26, 1998

Probing the structural basis of the catalytic activity of HIV-1 PR through total chemical protein synthesis

Journal of Molecular Structure: THEOCHEM, ISSN: 01661280

Maria Miller; Baca; J.K. Mohana Rao; Stephen B. H. Kent

January 22, 1998

Calcium-dependent Ret activation by GDNF and neurturin

Oncogene, ISSN: 09509232

Chika Nozaki; Naoya Asai; Hideki Murakami; Toshihide Iwashita; Yosuke Iwata; Keizo Horibe; Robert D. Klein; Rosenthal; Masahide Takahashi

January 15, 1998

Adenovector-mediated expression of human thrombopoietin cDNA in immune- compromised mice: Insights into the pathophysiology of osteomyelofibrosis

Journal of Immunology, ISSN: 00221767

Beat M. Frey; Shahin Rafii; Michael Teterson; Dan L. Eaton; Crystal; Malcolm A.S. Moore

January 9, 1998

Identification of a novel polyproline recognition site in the cytoskeletal associated protein, proline serine threonine phosphatase interacting protein

Journal of Biological Chemistry, ISSN: 00219258

Dowbenko; Spencer; Quan; Lasky

January 9, 1998

Photoaffinity labeling by 4-thiodideoxyuridine triphosphate of the HIV- 1 reverse transcriptase active site during synthesis. Sequence of the unique labeled hexapeptide

Journal of Biological Chemistry, ISSN: 00219258

Shanhua Lin; William J. Henzel; Sunil Nayak; Don Dennis

January 2, 1998

Identification of an inhibin receptor in gonadal tumors from inhibin α- subunit knockout mice

Journal of Biological Chemistry, ISSN: 00219258

Lawrence B. Draper; Matzuk; Veronica J. Roberts; Edward T. Cox; Jeffrey Weiss; Mather; Woodruff

January 1, 1998

Biological aspects of the intestinal epithelial barrier

Proceedings of the Controlled Release Society, ISSN: 10220178

Mrsny

January 1, 1998

Pharmacokinetics of a slower clearing tissue plasminogen activator variant, TNK-tPA, in patients with acute myocardial infarction

Thrombosis and Haemostasis, ISSN: 03406245

Modi; Stephen M. Eppler; Judy Breed; Christopher P. Cannon; Eugene Braunwald; Ted W. Love

January 1, 1998

Amino acid sequence similarity of Hev b 3 to two previously reported 27- and 23-kDa latex proteins allergenic to spina bifida patients

Allergy: European Journal of Allergy and Clinical Immunology, ISSN: 01054538

Yeang; Ward; Zamri; Dennis; Light

January 1, 1998

Activating Smoothened mutations in sporadic basal-cell carcinoma

Nature, ISSN: 00280836

Jingwu Xie; Maximilien Murone; Shiuh-Ming Luoh; Anne Ryan; Qimin Gu; Chaohui Zhang; Jeannette M. Bonifas; Ching-Wan Lam; Mary Hynes; Goddard; Rosenthal; Ervin H. Epstein Jr.; Frederic J. De Sauvage

January 1, 1998

Fourier-transform infrared spectroscopic investigation of the secondary structure of aqueous and dried recombinant human deoxyribonuclease I

Pharmacy and Pharmacology Communications, ISSN: 14608081

Henry R. Costantino; Bei Chen; Kai Griebenow; Chung C. Hsu; Steven J. Shire

January 1, 1998

Distinct expression patterns of notch family receptors and ligands during development of the mammalian inner ear

Mechanisms of Development, ISSN: 09254773

Lewis; Gretchen D. Frantz; David Carpenter; Frederic J. De Sauvage; Gao

January 1, 1998

AtDB, the Arabidopsis thaliana Database, and graphical-web-display of progress by the Arabidopsis genome initiative

Nucleic Acids Research, ISSN: 03051048

David J. Flanders; Shuai Weng; Fabien X. Petel; J. Michael Cherry

January 1, 1998

Mucoadhesive microparticles for antigen delivery

Proceedings of the Controlled Release Society, ISSN: 10220178

Claudia Witschi; Mrsny

January 1, 1998

Mucosal administration of a non-toxic Pseudomonas exotoxin-gp120 V3 loop chimera elevates gp120 specific IgG and IgA in the serum and saliva of BALB/c mice

Proceedings of the Controlled Release Society, ISSN: 10220178

Daugherty; Silva; Charlotte M. Fryling; David FitzGerald; Mrsny

January 1, 1998

Substantially attenuated hemodynamic responses to Escherichia coli- derived vascular endothelial growth factor given by intravenous infusion compared with bolus injection

Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565

Renhui Yang; Bunting; Annie Ko; Keyt; Modi; Zioncheck; Napoleone Ferrara; Hongkui Jin

January 1, 1998

Computer system validation: Value added activities meeting regulatory imperatives

Drug Information Journal, ISSN: 00928615

Woodrum

January 1, 1998

Effects of cardiotrophin-1 on haemodynamics and cardiac function in conscious rats

Cytokine, ISSN: 10434666

Hongkui Jin; Renhui Yang; Ko Annie; Diane Pennica; William I. Wood; Nicholas F. Paoni

January 1, 1998

Lymphocyte granule-mediated apoptosis: Matters of viral mimicry and deadly proteases

Immunology Today, ISSN: 01675699

Christopher J. Froelich; Vishva M. Dixit; Xiaohe Yang

January 1, 1998

Solvent evaporation processes for the production of controlled release biodegradable microsphere formulations for therapeutics and vaccines

Biotechnology Progress, ISSN: 87567938

Cleland

January 1, 1998

Nab1, a corepressor of NGFI-A (Egr-1), contains an active transcriptional repression domain

Molecular and Cellular Biology, ISSN: 02707306

Alex H. Swirnoff; Elizabeth D. Apel; John Svaren; Bradley R. Sevetson; Drazen B. Zimonjic; Nicholas C. Popescu; Jeffrey Milbrandt

January 1, 1998

Calcium-phosphate mediated DNA transfer into HEK-293 cells in suspension: Control of physicochemical parameters allows transfection in stirred media: Transfection and protein expression in mammalian cells

Cytotechnology, ISSN: 09209069

Martin Jordan; Christiane Köhne; Florian M. Wurm

January 1, 1998

Integrins α(v)β3 and α5β1 mediate attachment of lyme disease spirochetes to human cells

Infection and Immunity, ISSN: 00199567

Jenifer Coburn; Loranne Magoun; Bodary; John M. Leong

January 1, 1998

Chromatography in biotechnology: A user's perspective

LC-GC Europe, ISSN: 14716577

John Frenz

January 1, 1998

Stabilization of nerve growth factor during microencapsulation and release from microspheres

Proceedings of the Controlled Release Society, ISSN: 10220178

Lam; Duenas; Cleland

January 1, 1998

Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells

Development (Cambridge), ISSN: 09501991

Mengqing Xiang; Gao; Tama Hasson; Joyce J. Shin

January 1, 1998

Development of stable formulations for PLGA/PLA microsphere vaccines

Research in Immunology, ISSN: 09232494

Cleland

January 1, 1998

Pharmacokinetics, pharmacodynamics and tolerability of a potent, non-peptidic, GP IIb/IIIa receptor antagonist following multiple oral administrations of a prodrug form

Thrombosis and Haemostasis, ISSN: 03406245

Refino; Modi; Sherron L. Bullens; Cheryl Pater; Michael T. Lipari; Kirk D. Robarge; Brent Blackburn; Beresini; Thomas Weller; Beat Steiner; Bunting

January 1, 1998

Local delivery of vascular endothelial growth factor via PLGA depots for treatment of vascular disease

Proceedings of the Controlled Release Society, ISSN: 10220178

Ann Park; Duenas; Thomas W. Patapoff; Cleland

January 1, 1998

A data model for clinical study status reports

Drug Information Journal, ISSN: 00928615

David H. Christiansen; Sundin

January 1, 1998

Genetic approaches to the detection of contaminants in Escherichia coli fermentations

Biotechnology Progress, ISSN: 87567938

James R. Swartz; Nancy McFarland

January 1, 1998

Increased physical activity and the growth hormone-IGF-I axis in adolescent males

American Journal of Physiology - Regulatory Integrative and Comparative Physiology, ISSN: 03636119

Alon Eliakim; Jo Anne Brasel; Subburaman Mohan; Wai Lee T. Wong; Dan M. Cooper

January 1, 1998

A role for FADD in T cell activation and development

Immunity, ISSN: 10747613

Craig M. Walsh; Ben G. Wen; Arul M. Chinnaiyan; Karen M. O'Rourke; Vishva M. Dixit; Stephen M. Hedrick

January 1, 1998

Development and validation of the migraine-specific quality of life questionnaire

Headache, ISSN: 00178748

Priti Jhingran; Jane T. Osterhaus; David W. Miller; Jeffrey T. Lee; Leonard Kirchdoerfer

January 1, 1998

Development of a single-shot subunit vaccine for HIV-1. 5. Programmable in vivo autoboost and long lasting neutralizing response

Journal of Pharmaceutical Sciences, ISSN: 00223549

Cleland; Lim; Daugherty; Barron; Noelyn Desardin; Duenas; Eastman; Vennari; Wrin; Berman; Michael Powel

January 1, 1998

Adaptation to hyperglycemia enhances insulin secretion in glucokinase mutant mice

Diabetes, ISSN: 00121797

Seamus K. Sreenan; Brian N. Cockburn; Aaron C. Baldwin; Diane M. Ostrega; Matteo Levisetti; Andrew Grupe; Graeme I. Bell; Stewart; Michael W. Roe; Kenneth S. Polonsky

January 1, 1998

Raw materials as a source of contamination in large-scale cell culture.

Developments in biological standardization, ISSN: 03015149

Robert L. Garnick

January 1, 1998

Biological response to ErbB ligands in nontransformed cell lines correlates with a specific pattern of receptor expression

Endocrinology, ISSN: 00137227

Sundaresan; Penelope E. Roberts; King; Mark X. Sliwkowski; Mather

January 1, 1998

Therapeutic potential of neurotrophins for treatment of hearing loss

Molecular Neurobiology, ISSN: 08937648

Gao

January 1, 1998

The dormant in vivo phenotype of early stage primary human melanoma: Termination by overexpression of vascular endothelial growth factor

Angiogenesis, ISSN: 09696970

Liisa Bayko; Janusz Rak; Shan Man; Roy Bicknell; Napoleone Ferrara; Robert S. Kerbel

January 1, 1998

Real-time measurement of lysis of mural platelet deposits by fibrinolytic agents under arterial flow

Annals of Biomedical Engineering, ISSN: 00906964

Dionne A. Graham; Trevor C. Huang; Keyt; B. Rita Alevriadou

January 1, 1998

Purification and Physical Characterization of Cloned Human cAMP Phosphodiesterases PDE-4D and -4C

Cell Biochemistry and Biophysics, ISSN: 10859195

Natalie Saldou; Preston A. Baecker; Bin Li; Zhengyu Yuan; Rena Obernolte; James Ratzliff; Eric Osen; Kurt Jarnagin; Earl R. Shelton

January 1, 1998

Making informed choices: Medium, serum, and serum-free medium how to choose the appropriate medium and culture system for the model you wish to create

Methods in Cell Biology, ISSN: 0091679X

Mather

January 1, 1998

Preparation and biological activity of novel tricyclic GPIIb/IIIa antagonists

Bioorganic and Medicinal Chemistry, ISSN: 09680896

Kirk D. Robarge; Dina; Todd C. Somers; Arthur Lee; Thomas E. Rawson; Alan G. Olivero; Maureen Tischler; Robert R. Webb II; Kenneth J Weese; Ignacio Aliagas; Brent Blackburn

January 1, 1998

Evaluation of product comparability.

Developments in biological standardization, ISSN: 03015149

Stuart E. Builder

January 1, 1998

Periodontal repair in dogs: Effect of recombinant human transforming growth factor-β1 on guided tissue regeneration

Journal of Clinical Periodontology, ISSN: 03036979

Ulf M. E. Wikesjö; Saghi S. Razi; Thorarinn J. Sigurdsson; Dimitris N. Tatakis; Michael B. Lee; Ongpipattanakul; Tue H. Nguyen; Ross Hardwick

January 1, 1998

IL-3 does not contribute to platelet production in c-Mpl-deficient mice.

Stem Cells, ISSN: 10665099

Qi Chen; Gregg Solar; Dan L. Eaton; Frederic J. De Sauvage

January 1, 1998

Dosing, monitoring, and safety of growth hormone-replacement therapy in adults with growth hormone deficiency

Endocrinologist, ISSN: 10512144

Sandra L. Blethen

January 1, 1998

Expression of active human tissue-type plasminogen activator in Escherichia coli

Applied and Environmental Microbiology, ISSN: 00992240

Ji Qiu; James R. Swartz; George Georgiou

Join Our Team

The little things we do every day add up to big breakthroughs. Making a difference in the lives of millions starts when you make a change in yours.

Two Scientists Walk Into a Bar

Two Scientists Walk Into a Bar

Listen to our podcast, where researchers talk about their work answering the toughest questions in human biology.