Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12551 - 12600 OF 15396 RESULTS

Engineering hyperactive variants of human deoxyribonuclease I by altering its functional mechanism
Biochemistry, ISSN: 00062960
Clark Q. Pan; Lazarus
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Stereoselectivity of the Chinese hamster ovary cell sialidase: Sialoside hydrolysis with overall retention of configuration
Glycobiology, ISSN: 09596658
Yung-Hsiang Kao; Laura Lerner; Warner
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Metabolism of thrombopoietin (TPO) in vivo: Determination of the binding dynamics for TPO in mice
Blood, ISSN: 00064971
Stefanich; Tauri D. Senn; Ramon Widmer; Christine Fratino; Gilbert-Andre Keller; Fielder
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A stochastic model for the analysis of bivariate longitudinal AIDS data
Biometrics, ISSN: 0006341X
Sy; Jeremy M.G. Taylor; Cumberland
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Acquired B lymphocyte deficiency and chronic enterocolitis in a 3-year- old quarter horse
Veterinary Immunology and Immunopathology, ISSN: 01652427
MacLeay; Ames; Hayden; Daniel B. Tumas
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A mathematical model of sialylation of N-linked oligosaccharides in the trans-Golgi network
Glycobiology, ISSN: 09596658
Thomas J. Monica; Dana C. Andersen; Charles F. Goochee
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Induction of cross-reactive cytotoxic T-lymphocyte responses specific for HIV-1 gp120 using saponin adjuvant (QS-21) supplemented subunit vaccine formulations
Vaccine, ISSN: 0264410X
Newman; Wu; Gardner; Anderson; Kensil; Recchia; Coughlin; Powell
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Surface expression, polarization, and functional significance of CD73 in human intestinal epithelia
Journal of Clinical Investigation, ISSN: 00219738
Gregg R. Strohmeier; Wayne I. Lencer; Thomas W. Patapoff; Linda F. Thompson; Susan L. Carlson; Signa J. Moe; Denice K. Carnes; Mrsny; James L. Madara
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In vivo characterization of sustained-release formulations of human growth hormone
Journal of Pharmacology and Experimental Therapeutics, ISSN: 00223565
Lee; Gary Riley; OluFunmi Johnson; Cleland; Norman Kim; Margarita Charnis; Leone Bailey; Duenas; Shahzamani; Marian; Andrew J.S. Jones; Putney
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A Two-Step Approach to Measurement Error in Time-Dependent Covariates in Nonlinear Mixed-Effects Models, with Application to IGF-I Pharmacokinetics
Journal of the American Statistical Association, ISSN: 1537274X 01621459
Karen M. Higgins; Davidian; Giltinan
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Capillary zone electrophoresis at subzero temperatures II: Chiral separation of biogenic amines
Electrophoresis, ISSN: 01730835
Stacey Ma; Csaba Horváth
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Stereoselectivity of the Chinese hamster ovary cell sialidase: Sialoside hydrolysis with overall retention of configuration
Glycobiology, ISSN: 09596658
Kao; Laura Lerner; Warner
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Structural change and receptor binding in a chemokine mutant with a rearranged disulfide: X-ray structure of E38C/C50A IL-8 at 2 Å resolution
Proteins: Structure, Function and Bioinformatics, ISSN: 08873585
Eigenbrot; Henry B. Lowman; Linda Chee; Dean R. Artis
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Herpesvirus entry mediator, a member of the tumor necrosis factor receptor (TNFR) family, interacts with members of the TNFR-associated factor family and activates the transcription factors NF-κB and AP-1
Journal of Biological Chemistry, ISSN: 00219258
Scot A. Marsters; T. Merrill Ayres; Skubatch; Christa Gray; Mike Rothe; Avi Ashkenazi
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The stability of recombinant human growth hormone in poly(lactic-co-glycolic acid) (PLGA) microspheres
Pharmaceutical Research, ISSN: 07248741
Cleland; Mac; Brooks Boyd; Yang; Duenas; Yeung; Brooks; Chung C. Hsu; Chu; Mukku; Andrew J.S. Jones
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Spray dried powders and powder blends of recombinant human deoxyribonuclease (rhDNase) for aerosol delivery
Pharmaceutical Research, ISSN: 07248741
Chan; Clark; Gonda; Mumenthaler; Chung C. Hsu
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A role for the Wnt gene family in hematopoiesis: Expansion of multilineage progenitor cells
Blood, ISSN: 00064971
Timothy W. Austin; Gregg Solar; Francis C. Ziegler; Linda Liem; William Matthews
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Minimizing Peak Coalescence: High-Resolution Separation of Isotope Peaks in Partially Deamidated Peptides by Matrix-Assisted Laser Desorption/Ionization Fourier Transform Ion Cyclotron Resonance Mass Spectrometry
Analytical Chemistry, ISSN: 00032700
Stults
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Potent bifunctional anticoagulants: Kunitz domain-tissue factor fusion proteins
Biochemistry, ISSN: 00062960
Geoffrey F. Lee; Lazarus; Robert F. Kelley
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A soluble tissue factor mutant is a selective anticoagulant and antithrombotic agent
Blood, ISSN: 00064971
Robert F. Kelley; Refino; Mark P. O'Connell; Modi; Sehl; David G Lowe; Cheryl Pater; Bunting
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Stimulation of megakaryocyte and platelet production by a single dose of recombinant human thrombopoietin in patients with cancer
Annals of Internal Medicine, ISSN: 00034819
Saroj Vadhan-Raj; Lesley J. Murray; Carlos Bueso-Ramos; Shreyaskumar Patel; Saraswati P. Reddy; William K. Hoots; Taren Johnston; Nicholas E. Papadopoulous; Walter N. Hittelman; Dennis A. Johnston; Timothy A. Yang; Virginia Paton; Robert L. Cohen; Hellmann; Robert S. Benjamin; Hal E. Broxmeyer
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Induction of EAE in mice wtih recombinant human MOG, and treatment of EAE with a MOG peptide
Journal of Neuroimmunology, ISSN: 01655728
Devaux; Fran Enderlin; Barbara P. Wallner; Dawn E. Smilek
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Dual hormonal replacement therapy with insulin and recombinant human insulin-like growth factor (IGF)-I in insulin-dependent diabetes mellitus: Effects on the growth hormone/IGF/IGF-binding protein system
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Kathryn Thrailkill; Teresa Quattrin; Lester Baker; Jean Litton; Karen Dwigun; Melissa Rearson; Mary Poppenheimer; Debbie Kotlovker; Giltinan; Gesundheit; Paul M. Martha Jr.
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Reduced concentration of serum growth hormone (GH)-binding protein in children with chronic renal failure: Correlation with GH insensitivity
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Burkhard Tonshoff; Cronin; Marcel Reichert; Dieter Haffner; Anne-Margret Wingen; Werner Blum; Otto Mehls
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Adjunctive growth hormone during ovarian hyperstimulation increases levels of insulin-like growth factor binding proteins in follicular fluid: A randomized, placebo-controlled, cross-over study
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Jaron Rabinovici; Nicholas A. Cataldo; Pramila Dandekar; Stephen M. Rosenthal; Sharron E. Gargosky; Gesundheit; Martin
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Mapping of a cytoplasmic domain of the human growth hormone receptor that regulates rates of inactivation of Jak2 and Stat proteins
Journal of Biological Chemistry, ISSN: 00219258
Rebecca H. Hackett; Wang; Sharon Sweitzer; Gerald Feldman; William I. Wood; Andrew C. Larner
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Specificity determinants in neurotrophin-3 and design of nerve growth factor-based trkC agonists by changing central β-strand bundle residues to their neurotrophin-3 analogs
Biochemistry, ISSN: 00062960
Urfer; Tsoulfas; O'Connell; Presta
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Antibody humanization using monovalent phage display
Journal of Biological Chemistry, ISSN: 00219258
Baca; Presta; Shane J. O'Connor; James A. Wells
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Human platelets as a model for the binding and degradation of thrombopoietin
Blood, ISSN: 00064971
Fielder; Hass; Nagel; Stefanich; Ramon Widmer; Bennett; Gilbert-Andre Keller; Frederic J. De Sauvage; Dan L. Eaton
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Bone Marrow Can Function as a Lymphoid Organ during a Primary Immune Response under Conditions of Disrupted Lymphocyte Trafficking
Journal of Immunology, ISSN: 00221767
Ralph A. Tripp; David J. Topham; Susan R. Watson; Peter C. Doherty
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Nuclear transport of insulin-like growth factor-I and insulin-like growth factor binding protein-3 in opossum kidney cells
Endocrinology, ISSN: 00137227
Wenlu Li; Janet Fawcett; Widmer; Fielder; Ralph Rabkin; Gilbert-Andre Keller
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Metal-catalyzed oxidation of histidine in human growth hormone: Mechanism, isotope effects, and inhibition by a mild denaturing alcohol
Journal of Biological Chemistry, ISSN: 00219258
Fang Zhao; Elena Ghezzo-Schöneich; Gaby I. Aced; Jinyang Hong; Terry Milby; Christian Schöneich
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Preparation and characterization of PEGylated human growth hormone and human growth hormone mutants
American Chemical Society, Polymer Preprints, Division of Polymer Chemistry, ISSN: 00323934
Olson; Richard L. Gehant; Mukku; Kathy L. O'Connell; Brandon Tomlinson; Klara Totpal; Winkler
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Remarkable sequence conservation of transcripts encoding amphibian and mammalian homologues of quaking, a KH domain RNA-binding protein
Gene, ISSN: 03781119
Aaron M. Zorn; Matthew Grow; Kristin D. Patterson; Tom A. Ebersole; Qi Chen; Karen Artzt; Paul A. Krieg
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Growth hormone attenuates early left ventricular remodeling and improves cardiac function in rats with large myocardial infarction
Journal of the American College of Cardiology, ISSN: 07351097
Antonio Cittadini; Jessica D. Grossman; Raffaele Napoli; Sarah E. Katz; Hinrik Strömer; Robert J. Smith; Ross Clark; James P. Morgan; Pamela Douglas
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Anarchy of the macrophage reaction: Endotoxins and sepsis Anarchie der Makrophagenreaktion Endotoxine und Sepsis
Krankenhauspharmazie, ISSN: 01737597
Ralf R. Schumann
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Immunocytochemical localization of O2-sensing protein (NADPH oxidase) in chemoreceptor cells
Microscopy Research and Technique, ISSN: 1059910X
Youngson; Nurse; Yeger; John T. Curnutte; Vollmer; Wong; Cutz
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A non-radioactive complement-dependent cytotoxicity assay for anti-CD20 monoclonal antibody
Journal of Immunological Methods, ISSN: 00221759
Hélène Gazzano-Santoro; Peter Ralph; Thomas C. Ryskamp; Chen; Mukku
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Feasibility of protein spray coating using a fluid-bed Wurster processor
Biotechnology and Bioengineering, ISSN: 00063592
Maa; Chung C. Hsu
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Expression of Chemokine Receptors by Subsets of Neurons in the Central Nervous System
Journal of Immunology, ISSN: 00221767
Richard Horuk; Alvin W. Martin; Zi-Xuan Wang; Laura Schweitzer; Alexandra Gerassimides; Haihong Guo; Zhao-Hai Lu; Joseph Hesselgesser; H. Daniel Perez; Jin Kim; Joseph Parker; Hadley; Stephen C. Peiper
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A novel protein-tyrosine phosphatase related to the homotypically adhering κ and μ receptors
Journal of Biological Chemistry, ISSN: 00219258
Jill Cheng; Kai Wu; Armanini; Nancy A. O'Rourke; Dowbenko; Lasky
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The role of nerve growth factor in a model of visceral inflammation
Neuroscience, ISSN: 03064522
Dmitrieva; David L. Shelton; Rice; McMahon
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The prehospital electrocardiogram in acute myocardial infarction: Is its full potential being realized?
Journal of the American College of Cardiology, ISSN: 07351097
John G. Canto; William J. Rogers; Laura J. Bowlby; William J. French; Douglas J. Pearce; Douglas Weaver
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Neurotrophin-3- and norepinephrine-mediated adrenergic differentiation and the inhibitory action of desipramine and cocaine
Journal of Neurobiology, ISSN: 00223034
Jian-Min Zhang; Jessica Dix; Carol J. Langtimm-Sedlak; Thomas Trusk; Brett Schroeder; Raymond Hoffmann; Aldo D. Strosberg; Winslow; Maya Sieber-Blum
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Identification of mouse liver proteins on two-dimensional electrophoresis gels by matrix-assisted laser desorption/ionization mass spectrometry of in situ enzymatic digests
Electrophoresis, ISSN: 01730835
Kathy L. O'Connell; Stults
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Postmitotic neurons migrate tangentially in the cortical ventricular zone
Development (Cambridge), ISSN: 09501991
Nancy A. O'Rourke; Anjen Chenn; Susan K. McConnell
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AL-1-induced growth cone collapse of rat cortical neurons is correlated with REK7 expression and rearrangement of the actin cytoskeleton
European Journal of Neuroscience, ISSN: 0953816X
Caras
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Role of high-performance liquid chromatographic protein analysis in developing fermentation processes for recombinant human growth hormone, relaxin, antibody fragments and lymphotoxin
Journal of Chromatography A, ISSN: 00219673
Fredric S. Jacobson; John Hanson; Pin-Yee Wong; Michael G. Mulkerrin; James Deveney; Dorothea Reilly; Susan C. Wong
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From peptide to non-peptide. 3. Atropisomerie GPIIbIIIa antagonists containing the 3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione nucleus
Journal of Medicinal Chemistry, ISSN: 00222623
Brent Blackburn; Arthur Lee; Mark Baier; Benjamin Kohl; Alan G. Olivero; Regina Matamoros; Kirk D. Robarge; Robert S. McDowell
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Model peptide studies demonstrate that amphipathic secondary structures can be recognized by the chaperonin GroEL (cpn60)
Journal of Biological Chemistry, ISSN: 00219258
Bill T. Brazil; Cleland; Robert S. McDowell; Nicholas J. Skelton; Kenneth J. Paris; Paul M. Horowitz
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