Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12601 - 12650 OF 15396 RESULTS

February 21, 1997

Signaling of the cardiotrophin-1 receptor: Evidence for a third receptor component

Journal of Biological Chemistry, ISSN: 00219258

Olivier Robledo; Maryvonne Fourcin; Sylvie Chevalier; Catherine Guillet; Patrick Auguste; Annick Pouplard-Barthelaix; Diane Pennica; Hugues Gascan

February 20, 1997

CRF2-4: Isolation of cDNA clones encoding the human and mouse proteins

Gene, ISSN: 03781119

Gibbs; Diane Pennica

February 17, 1997

Heterogeneity of serum albumin samples with respect to solid-state aggregation via thiol-disulfide interchange - Implications for sustained release from polymers

Journal of Controlled Release, ISSN: 01683659

Henry R. Costantino; Lisa Shieh; Klibanov; Langer

February 17, 1997

Thrombopoietin: The primary regulator of megakaryocytopoiesis and thrombopoiesis

Experimental Hematology, ISSN: 0301472X

Dan L. Eaton; Frederic J. De Sauvage

February 11, 1997

Biochemical characterization of recombinant fusions of lipopolysaccharide binding protein and bactericidal/permeability-increasing protein. Implications in biological activity

Journal of Biological Chemistry, ISSN: 00219258

Susan L. Abrahamson; Hsiu-Mei Wu; Robert E. Williams; Ken Der; Nneka Ottah; Roger Little; Hélène Gazzano-Santoro; Georgia Theofan; Bauer; Scott Leigh; Anne Orme; Arnold H. Horwitz; Stephen F. Carroll; Russell L Dedrick

February 5, 1997

On the pH memory of lyophilized compounds containing protein functional groups

Biotechnology and Bioengineering, ISSN: 00063592

Henry R. Costantino; Kai Griebenow; Langer; Klibanov

February 1, 1997

Chemoattractant Cross-Desensitization of the Human Neutrophil IL-8 Receptor Involves Receptor Internalization and Differential Receptor Subtype Regulation

Journal of Immunology, ISSN: 00221767

Ian Sabroe; Timothy J. Williams; Hébert; Paul D. Collins

February 1, 1997

Isolation and characterization of the platelet-derived growth factor beta receptor promoter

Developmental Dynamics, ISSN: 10588388

Eve Shinbrot; Xiang Liao; Williams

February 1, 1997

Down-Regulation of FcεRI Expression on Human Basophils during in Vivo Treatment of Atopic Patients with Anti-IgE Antibody

Journal of Immunology, ISSN: 00221767

Donald W. Macglashan Jr.; Bruce S. Bochner; Daniel C. Adelman; Paula Jardieu; Alkis Togias; Jane McKenzie-White; Sherry A. Sterbinsky; Robert G. Hamilton; Lawrence M. Lichtenstein

February 1, 1997

Association of Csk-homologous kinase (CHK) (formerly MATK) with HER- 2/ErbB-2 in breast cancer cells

Journal of Biological Chemistry, ISSN: 00219258

Sheila Zrihan-Licht; Jinkyu Lim; Iafa Keydar; Mark X. Sliwkowski; Jerome E. Groopman; Hava Avraham

February 1, 1997

Respective role of TNF receptors in the development of experimental cerebral malaria

Journal of Neuroimmunology, ISSN: 01655728

Rudolf Lucas; Jin-Ning Lou; Pierre Juillard; Mark Moore; Horst Bluethmann; Georges E. Grau

January 22, 1997

A general method for constraining short peptides to an α-helical conformation

Journal of the American Chemical Society, ISSN: 00027863

J. Christopher Phelan; Nicholas J. Skelton; Andrew Braisted; Robert S. McDowell

January 15, 1997

The effect of chemical modifications on octanol/water partition (log D) and permeabilities across Caco-2 monolayers

Advanced Drug Delivery Reviews, ISSN: 0169409X

Rubas; Cromwell

January 15, 1997

Metal-catalyzed photooxidation of histidine in human growth hormone

Analytical Biochemistry, ISSN: 00032697

Suh Chang; Glen Teshima; Terry Milby; Beth Gillece-Castro; Eleanor Canova-Davis

January 7, 1997

Sterically stabilized anti-HER2 immunoliposomes: Design and targeting to human breast cancer cells in vitro

Biochemistry, ISSN: 00062960

Dmitri Kirpotin; Park; Hong; Samuel Zalipsky; Wenlu Li; Paul J. Carter; Benz; Papahadjopoulos

January 1, 1997

Factors influencing the time to thrombolysis in acute myocardial infarction

Archives of Internal Medicine, ISSN: 00039926

Costas Lambrew; Laura J. Bowlby; William J. Rogers; Nisha C. Chandra; Douglas Weaver

January 1, 1997

Vascular endothelial growth factor expression is higher in differentiated thyroid cancer than in normal or benign thyroid

Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X

Euy Y. Soh; Quan-Yang Duh; Saif A. Sobhi; Dave M. Young; Howard D. Epstein; Mariwil G. Wong; Y. Kit Garcia; Young D. Min; Richard F. Grossman; Allan E. Siperstein; Orlo H. Clark

January 1, 1997

Consequences of growth hormone deficiency on cardiac structure, function, and β-adrenergic pathway: Studies in mutant dwarf rats

Endocrinology, ISSN: 00137227

Antonio Cittadini; Hinrik Strömer; Dorothy E. Vatner; Jessica D. Grossman; Sarah E. Katz; Ross Clark; James P. Morgan; Pamela Douglas

January 1, 1997

Partial growth-hormone insensitivity: The role of growth-hormone receptor mutations in idiopathic stature

Journal of Pediatrics, ISSN: 00223476

Goddard; Patrick Dowd; Chernausek; Geffner; Gertner; Hintz; Hopwood; Selna L. Kaplan; Plotnick; Alan D. Rogol; Rosenfield; Saenger; Nelly Mauras; Hershkopf; Angulo; Kenneth M. Attie

January 1, 1997

Pioneering recombinant growth hormone manufacturing: Pounds produced per mile of height

Journal of Pediatrics, ISSN: 00223476

Cronin

January 1, 1997

National Cooperative Growth Study substudy VI: The clinical utility of growth-hormone-binding protein, insulin-like growth factor I, and insulin- like growth factor-binding protein 3 measurements

Journal of Pediatrics, ISSN: 00223476

Kenneth M. Attie; Joanne R. Julius; Catherine Stoppani; Amy Chen Rundle

January 1, 1997

A risk-benefit assessment of growth hormone use in children

Drug Safety, ISSN: 01145916

Sandra L. Blethen; Margaret H. Macgillivray

January 1, 1997

Peripheral vascular stenosis in apolipoprotein e-deficient mice: Potential roles of lipid deposition, medial atrophy, and adventitial inflammation

Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN: 10795642

Hong Seog Seo; Donna M. Lombardi; Patti Polinsky; Powell-Braxton; Bunting; Schwartz; Michael E. Rosenfeld

January 1, 1997

Determining the water sorption monolayer of lyophilized pharmaceutical proteins

Journal of Pharmaceutical Sciences, ISSN: 00223549

Henry R. Costantino; Curley; Chung C. Hsu

January 1, 1997

Developing Pharmaceutical Protein Formulations: Assumptions and Analytical Tools

ACS Symposium Series, ISSN: 00976156

Shahrokh

January 1, 1997

Targeting technologies - The expanding patent literature

Journal of Drug Targeting, ISSN: 1061186X

Mrsny

January 1, 1997

Specification and Survival of Dopaminergic Neurons in the Mammalian Midbrain

Advances in Pharmacology, ISSN: 10543589

Rosenthal

January 1, 1997

NGF binding to p75 enhances the sensitivity of sensory and sympathetic neurons to NGF at different stages of development

Molecular and Cellular Neuroscience, ISSN: 10447431

Antony Horton; Laramee; Sean Wyatt; Shih; Winslow; Alun M. Davies

January 1, 1997

Hematologically important mutations: X-linked chronic granulomatous disease - An update

Blood Cells, Molecules, and Diseases, ISSN: 10799796

Heyworth; John T. Curnutte; Julie Rae; Noack; Andrew R. Cross

January 1, 1997

P-115. Recombinant human (rh) GHBP: Effects on GH action in the rat

Endocrinology and Metabolism, Supplement, ISSN: 1074939X

Deborah L. Mortensen; Carlsson; Winkler; Ross Clark

January 1, 1997

The Pharmaceutical Development of Insulin: Historical Perspectives and Future Directions

ACS Symposium Series, ISSN: 00976156

Henry R. Costantino; Stanley Liauw; Samir Mitragotri; Langer; Klibanov; Victoria Sluzky

January 1, 1997

Growth hormone/IGF-I and/or resistive exercise maintains myonuclear number in hindlimb unweighted muscles

Journal of Applied Physiology, ISSN: 87507587

Allen; Jon K. Linderman; Roy; Richard E. Grindeland; Mukku; Edgerton

January 1, 1997

MyD88: An adapter that recruits IRAK to the IL-1 receptor complex

Immunity, ISSN: 10747613

Holger Wesche; William J. Henzel; Wendy Shillinglaw; Shyun Li; Zhaodan Cao

January 1, 1997

The role of assay validation in specification development.

Developments in biological standardization, ISSN: 03015149

Baffi

January 1, 1997

O-015. rhIGF-I: Differential sensitivity to SQ bolus vs continuous delivery

Endocrinology and Metabolism, Supplement, ISSN: 1074939X

Nelly Mauras; Paul M. Martha Jr.; Quarmby; Haymond

January 1, 1997

Preparation and Characterization of Poly(ethylene glycol)ylated Human Growth Hormone Antagonist

ACS Symposium Series, ISSN: 00976156

Olson; Richard L. Gehant; Mukku; Kathy L. O'Connell; Brandon Tomlinson; Klara Totpal; Winkler

January 1, 1997

Specifications from a biotechnology industry perspective.

Developments in biological standardization, ISSN: 03015149

Robert L. Garnick

January 1, 1997

Csk and BatK Show Opposite Temporal Expression in the Rat CMS: Consistent with its Late Expression in Development, BatK Induces Differentiation of PC12 Cells

European Journal of Neuroscience, ISSN: 0953816X

Sophia S. Kuo

January 1, 1997

Process model and recipe structure, the conceptual design for a flexible batch plant

ISA Transactions, ISSN: 00190578

Hans Koning-Bastiaan

January 1, 1997

Physiological regulation of epithelial tight junctions is associated with myosin light-chain phosphorylation

American Journal of Physiology - Cell Physiology, ISSN: 03636143

Turner; Brian K. Rill; Susan L. Carlson; Denice K. Carnes; Rachel Kerner; Mrsny; James L. Madara

January 1, 1997

Normal platelets and megakaryocytes are produced in vivo in the absence of thrombopoietin

Blood, ISSN: 00064971

Bunting; Ramon Widmer; Michael T. Lipari; Linda Rangell; Hope Steinmetz; Karen Carver-Moore; Mark Moore; Gilbert-Andre Keller; Frederic J. De Sauvage

January 1, 1997

Stimulating effect of both human recombinant inhibin A and activin A on immature porcine Leydig cell functions in vitro

Endocrinology, ISSN: 00137227

Hervé Lejeune; Franck Chuzel; Pascale Sanchez; Philippe Durand; Mather; José M. Saez

January 1, 1997

Analysis of rat vestibular hair cell development and regeneration using calretinin as an early marker

Journal of Neuroscience, ISSN: 02706474

Zheng; Gao

January 1, 1997

Mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Its binding motif for α4β7 and role in experimental colitis

Immunologic Research, ISSN: 0257277X

Sherman Fong; Susan Jones; Renz; Chiu; Anne Ryan; Presta; Jackson

January 1, 1997

Antioxidants for prevention of methionine oxidation in recombinant monoclonal antibody HER2

Journal of Pharmaceutical Sciences, ISSN: 00223549

Lam; Yang; Cleland

January 1, 1997

Promiscuous use of CC and CXC chemokine receptors in cell-to-cell fusion mediated by a human immunodeficiency virus type 2 envelope protein

Journal of Virology, ISSN: 0022538X

Romke Bron; Klasse; David Wilkinson; Clapham; Annegret Pelchen-Matthews; Christine A. Power; Timothy N. C. Wells; Jin Kim; Stephen C. Peiper; James A. Hoxie; Mark Marsh

January 1, 1997

Ischemic stroke injury is reduced in mice lacking a functional NADPH oxidase

Stroke, ISSN: 00392499

Walder; Green; Darbonne; Joanne Mathias; Julie Rae; Mary C. Dinauer; John T. Curnutte; G. Roger Thomas

January 1, 1997

Receptors for the chemoattractants C5a and IL-8 are clustered on the surface of human neutrophils

Journal of Histochemistry and Cytochemistry, ISSN: 00221554

Gary D. Gray; Sharon R. Hasslen; Julia A. Ember; David F. Carney; Michael J. Herron; Stanley L. Erlandsen; Robert D. Nelson

January 1, 1997

γ-heregulin: A novel heregulin isoform that is an autocrine growth factor for the human breast cancer cell line, MDA-MB-175

Oncogene, ISSN: 09509232

Gabriele Schaefer; V. Danial Fitzpatrick; Mark X. Sliwkowski

January 1, 1997

The crystal structure of vascular endothelial growth factor (VEGF) refined to 1.93 Å resolution: Multiple copy flexibility and receptor binding

Structure, ISSN: 09692126

Yves A. Muller; Hans W. Christinger; Keyt; De Vos

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