Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 12851 - 12900 OF 15396 RESULTS

Novel analog of atrial natriuretic peptide selective for receptor-A produces increased diuresis and natriuresis in rats
Journal of Clinical Investigation, ISSN: 00219738
Hongkui Jin; Bing Li; Cunningham; Jeffrey Tom; Renhui Yang; Sehl; G. Roger Thomas; Annie Ko; David A. Oare; David G Lowe
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Functional and Structural Characterization of the Eosinophil P-Selectin Ligand
Journal of Immunology, ISSN: 00221767
Fiona A. Symon; Michael B. Lawrence; Mairi L. Williamson; Garry M. Walsh; Susan R. Watson; Andrew J. Wardlaw
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A novel protein tyrosine phosphatase expressed in Iin(lo)CD34(hi)Sca(hi) hematopoietic progenitor cells
Blood, ISSN: 00064971
Jill Cheng; Lisa Daimaru; Christopher Fennie; Lasky
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I-TRAF is a novel TRAF-interacting protein that regulates TRAF-mediated signal transduction
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Mike Rothe; Jessie Xiong; Hong-Bing Shu; Keith Williamson; Goddard; David V. Goeddel
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Engineering actin-resistant human DNase I for treatment of cystic fibrosis
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Jana S. Ulmer; Herzka; Toy; Baker; Dodge; Sinicropi; Steven Shak; Lazarus
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Orally active fibrinogen receptor antagonists. 2. Amidoximes as prodrugs of amidines
Journal of Medicinal Chemistry, ISSN: 00222623
Thomas Weller; Leo Alig; Beresini; Brent Blackburn; Bunting; Paul Hadváry; Marianne Hürzeler Müller; Dietmar Knopp; Bernard Levet-Trafit; Michael T. Lipari; Modi; Marcel Müller; Refino; Monique Schmitt; Peter Schönholzer; Sabine Weiss; Beat Steiner
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Characterization of a multicomponent receptor for GDNF
Nature, ISSN: 00280836
Treanor; Goodman; Frederic J. De Sauvage; Donna Stone; Kris Poulsen; Beck; Christa Gray; Armanini; Richard A. Pollock; Franz Hefti; Phillips; Goddard; Mark Moore; Anna Buj-Bello; Alun M. Davies; Naoya Asai; Masahide Takahashi; Vandien; Christopher E. Henderson; Rosenthal
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Renal and neuronal abnormalities in mice lacking GDNF
Nature, ISSN: 00280836
Mark Moore; Robert D. Klein; Isabel Fariñas; Hans Sauer; Armanini; Phillips; Louis F. Reichardt; Anne Ryan; Karen Carver-Moore; Rosenthal
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Extensive motor neuron survival in the absence of secondary skeletal muscle fiber formation
Journal of Neuroscience Research, ISSN: 03604012
Thomas J. Brennan; Olson; Klein; Winslow
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Synchronous onset of NGF and TrkA survival dependence in developing dorsal root ganglia
Journal of Neuroscience, ISSN: 02706474
Fletcher A. White; Silos-Santiago; Derek C. Molliver; Merry Nishimura; Phillips; Barbacid; William D. Snider
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Novel natriuretic peptide receptor/guanylyl cyclase A-selective agonist inhibits angiotensin II- and forskolin-evoked aldosterone synthesis in a human zona glomerulosa cell line
Molecular Pharmacology, ISSN: 0026895X
Linda J. Olson; David G Lowe; Drewett
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Low levels of erythroid and myeloid progenitors in thrombopoietin- and c- mpl-deficient mice
Blood, ISSN: 00064971
Karen Carver-Moore; Hal E. Broxmeyer; Shiuh-Ming Luoh; Scott Cooper; Jipeng Peng; Samuel A. Burstein; Mark Moore; Frederic J. De Sauvage
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Virtual units + S88 = flexible pilot plant
InTech, ISSN: 0192303X
Richard E. Parapar; Korkmaz
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Comparative analysis of the structure and function of the chicken c-myc and v-myc genes: v-myc is a more potent inducer of cell proliferation and apoptosis than c-myc
Oncogene, ISSN: 09509232
Christos J. Petropoulos; Iris Givol; Stephen H. Hughes
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Hormone mimicry
Science, ISSN: 00368075
James A. Wells
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IFN-α induces autoimmune T cells through the induction of intracellular adhesion molecule-1 and B7.2
Journal of Immunology, ISSN: 00221767
Debasis Chakrabarti; Hultgren; Stewart
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The use of high-performance anion-exchange chromatography and matrix- assisted laser desorption/ionization time-of-flight mass spectrometry to monitor and identify oligosaccharide degradation
Analytical Biochemistry, ISSN: 00032697
Field; Damon I. Papac; Andrew J.S. Jones
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Selection for genes encoding secreted proteins and receptors
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Robert D. Klein; Qimin Gu; Goddard; Rosenthal
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Heregulin is rapidly translocated to the nucleus and its transport is correlated with c-myc induction in breast cancer cells
Oncogene, ISSN: 09509232
Wenlu Li; Park; Andrew Nuijens; Mark X. Sliwkowski; Gilbert-Andre Keller
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The role of endogenous nerve growth factor in human diabetic neuropathy
Nature Medicine, ISSN: 10788956
Anand; Giorgio Terenghi; Warner; Kopelman; Williams-Chestnut; Sinicropi
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Epitope mapping by mass spectrometry: Determination of an epitope on HIV-1IIIB p26 recognized by a monoclonal antibody
Journal of Immunology, ISSN: 00221767
Carol E. Parker; Damon I. Papac; Sonja K. Trojak; Kenneth B. Tomer
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A splice variant of the neurotrophin receptor trkB with increased specificity for brain-derived neurotrophic factor
EMBO Journal, ISSN: 02614189
Christine Strohmaier; Bruce D. Carter; Urfer; Yves-Alain Barde; Georg Dechant
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Characterization of a novel component of the peroxisomal protein import apparatus using fluorescent peroxisomal proteins
EMBO Journal, ISSN: 02614189
Jennifer E. Kalish; Gilbert-Andre Keller; James C. Morrell; Stephanie J. Mihalik; Barbara Smith; James M. Cregg; Stephen J. Gould
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A month-long effect from a single injection of microencapsulated human growth hormone
Nature Medicine, ISSN: 10788956
OluFunmi Johnson; Cleland; Lee; Margarita Charnis; Duenas; Warren Jaworowicz; Douglas Shepard; Shahzamani; Andrew J.S. Jones; Putney
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Physical mapping and genomic structure of the human TNFR2 gene
Genomics, ISSN: 08887543
Christian P. Beltinger; Peter S. White; John M. Maris; Erik P. Sulman; Sanford J. Jensen; Denis LePaslier; Barbara J. Stallard; David V. Goeddel; Frederic J. De Sauvage; Garrett M. Brodeur
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Exchanging interleukin-8 and melanoma growth-stimulating activity receptor binding specificities
Journal of Biological Chemistry, ISSN: 00219258
Henry B. Lowman; Paul H. Slagle; Laura DeForge; Wirth; Beth Gillece-Castro; James H. Bourell; Wayne J. Fairbrother
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Insulin regulates heregulin binding and ErbB3 expression in rat hepatocytes
Journal of Biological Chemistry, ISSN: 00219258
Robert S. Carver; Mark X. Sliwkowski; Silvio Sitaric; William E. Russell
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Structural characterization of blood group A glycosphingolipids recognized by the antibody 3G9-A
Glycoconjugate Journal, ISSN: 02820080
Briggs; Robert E. Mandrell; Bruce A. Macher
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Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family
Journal of Biological Chemistry, ISSN: 00219258
Pitti; Scot A. Marsters; Siegfried Ruppert; Christopher J. Donahue; Alison Moore; Avi Ashkenazi
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Cardiovascular effects of insulin-like growth factor-1 and growth hormone in chronic left ventricular failure in the rat
Circulation, ISSN: 00097322
Robert L. Duerr; M. Dan McKirnan; Ronald D. Gim; Ross Clark; Kenneth R. Chien; John Ross Jr.
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Minimizing a binding domain from protein A
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Andrew Braisted; James A. Wells
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Effects of vascular endothelial growth factor on hemodynamics and cardiac performance
Journal of Cardiovascular Pharmacology, ISSN: 01602446
Renhui Yang; G. Roger Thomas; Bunting; Annie Ko; Napoleone Ferrara; Keyt; Ross; Hongkui Jin
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Heparin induces dimerization and confers proliferative activity onto the hepatocyte growth factor antagonists NK1 and NK2
Journal of Cell Biology, ISSN: 00219525
Ralph H. Schwall; Chang; Godowski; David W. Kahn; Kenneth J. Hillan; Kenneth D. Bauer; Zioncheck
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A detailed 1H and 13C NMR study of a repeating disaccharide of hyaluronan: The effect of sodium and calcium ions
Carbohydrate Research, ISSN: 00086215
Wanda Sicińska; Laura Lerner
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Effects of additives on heat denaturation of rhDNase in solutions
Pharmaceutical Research, ISSN: 07248741
Chan; Kwok-Leung Au-Yeung; Gonda
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Release of leukemia inhibitory factor in primate sepsis: Analysis of the role of TNF-α
Journal of Immunology, ISSN: 00221767
Patty M. Jansen; Irma W. De Jong; Margreet Hart; K.Jin Kim; Lucien A. Aarden; Lerner B. Hinshaw; Fletcher B. Taylor Jr.; C. Erik Hack
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Hypoxia regulates vascular endothelial growth factor receptor KDR/Flk gene expression through adenosine A2 receptors in retinal capillary endothelial cells
Investigative Ophthalmology and Visual Science, ISSN: 01460404
Hitoshi Takagi; George L. King; Napoleone Ferrara; Lloyd Paul Aiello
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Unesterified long chain fatty acids inhibit the binding of single chain urokinase to the urokinase receptor
Biochemistry, ISSN: 00062960
Abd Al-Roof Higazi; Joseph F. Aceto; Douglas Kniss; Rosalyn Upson; Robert L. Cohen; David A. Dichek; Douglas B. Cines
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Outcome of a four-year randomized study of daily versus three times weekly somatropin treatment in prepubertal naive growth hormone-deficient children
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Margaret H. Macgillivray; Joyce Baptista; Ann J. Johanson
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Safety of recombinant deoxyribonucleic acid-derived growth hormone: The National Cooperative Growth Study experience
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Sandra L. Blethen; David B. Allen; David Graves; Gilbert P. August; Thomas Moshang Jr.; Rosenfeld
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Mutations of the growth hormone receptor - Widening the search
Journal of Clinical Endocrinology and Metabolism, ISSN: 0021972X
Kenneth M. Attie
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High-level production of recombinant proteins in CHO cells using a dicistronic DHFR intron expression vector
Nucleic Acids Research, ISSN: 03051048
Brian K. Lucas; Lynne Giere; Richard A. Demarco; Amy Shen; Chisholm; Crowley
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α-subunit of farnesyltransferase is phosphorylated in vivo: Effect of protein phosphatase-1 on enzymatic activity
Biochemical and Biophysical Research Communications, ISSN: 0006291X
Amit Kumar; Beresini; Punita Dhawan; Kamal D. Mehta
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Membrane fouling in sterile filtration of recombinant human growth hormone
Biotechnology and Bioengineering, ISSN: 00063592
Maa; Chung C. Hsu
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Differentiation of follicular dendritic cells and full antibody responses require tumor necrosis factor receptor-1 signaling
Journal of Experimental Medicine, ISSN: 00221007
Michel Le Hir; Horst Bluethmann; Marie H. Kosco-Vilbois; Matthias Müller; Franco Di Padova; Mark Moore; Bernhard Ryffel; Hans-Pietro Eugster
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High-level expression and characterization of a purified 142-residue polypeptide of the prion protein
Biochemistry, ISSN: 00062960
Ingrid Mehlhorn; Darlene Groth; Johannes Stöckel; Moffat; Dorothea Reilly; Yansura; W. Scott Willett; Michael Baldwin; Robert Fletterick; Fred E. Cohen; Richard L. Vandlen; Henner; Stanley B. Prusiner
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Inhalation therapy with recombinant human deoxyribonuclease I
Advanced Drug Delivery Reviews, ISSN: 0169409X
Gonda
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Neonatal transplantation tolerance is associated with a systemic reduction in memory cells, altered chimeric cell phenotype, and modified eicosanoid and cytokine production
Transplantation, ISSN: 00411337
Phillip Ruiz; Mehdi Nassiri; Shahik K. Gregorian; Ana L. Viciana; J. Wayne Streilein
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Triglyceride enriched lipoprotein particles correlate with the severity of coronary artery disease
Atherosclerosis, ISSN: 00219150
Koren; Clinton Corder; Gudrun Mueller; Hose Centurion; Glen Hallum; James Fesmire; Walter D. McConathy; Petar Alaupovic
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Targeted disruption of the mouse apobec-1 gene abolishes apolipoprotein B mRNA editing and eliminates apolipoprotein B48
Journal of Biological Chemistry, ISSN: 00219258
Ken-Ichi Hirano; Stephen G. Young; Robert Farese; Jennifer Ng; Eric Sande; Warburton; Powell-Braxton; Nicholas O. Davidson
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