Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13051 - 13100 OF 15397 RESULTS

January 1, 1996

The role of protein-solvent interactions in protein unfolding

Current Opinion in Biotechnology, ISSN: 09581669

Celia A. Schiffer; Volker Dötsch

January 1, 1996

RhNGF slow unfolding is not due to proline isomerization: Possibility of a cystine knot loop-threading mechanism

Protein Science, ISSN: 09618368

Linda R. De Young; Louis E. Burton; Jun Liu; Powell; Charles H. Schmelzer; Nicholas J. Skelton

January 1, 1996

Trends in mortality in older women: Findings from the Nun Study

Journals of Gerontology - Series B Psychological Sciences and Social Sciences, ISSN: 10795014

Steven M. Butler; David A. Snowdon

January 1, 1996

Hematopoietic receptor complexes

Annual Review of Biochemistry, ISSN: 00664154

James A. Wells; De Vos

January 1, 1996

Caulobacter Lon protease has a critical role in cell-cycle control of DNA methylation

Genes and Development, ISSN: 08909369

Rachel Wright; Craig Stephens; Gary Zweiger; Lucy Shapiro; Alley

January 1, 1996

Monitoring growth hormone treatment: Safety considerations

Endocrinologist, ISSN: 10512144

Sandra L. Blethen

January 1, 1996

A role for leptin and its cognate receptor in hematopoiesis

Current Biology, ISSN: 09609822

Brian D. Bennett; Gregg Solar; Jean Q. Yuan; Joanne Mathias; G. Roger Thomas; William Matthews

January 1, 1996

Spatial and nonspatial learning in mice: Effects of S100β overexpression and age

Neurobiology of Learning and Memory, ISSN: 10747427

Gerlai; John C. Roder

January 1, 1996

Hepatocyte growth factor: A cytokine mediating endothelial migration in inflammatory arthritis

Arthritis and Rheumatism, ISSN: 00043591

Alisa Koch; Margaret M. Halloran; Shigeru Hosaka; Manisha R. Shah; Catherine J. Haskell; Steven K. Baker; Ralph J. Panos; G. Kenneth Haines; Bennett; Richard M. Pope; Napoleone Ferrara

January 1, 1996

Reproductive effects of chronic administration of murine interferon- gamma

Reproductive Toxicology, ISSN: 08906238

Bussiere; Laurel M. Hardy; Alan M. Hoberman; John A. Foss; Mildred S. Christian

January 1, 1996

Validation of peptide mapping for protein identity and genetic stability. Biologics and biotechnology section, pharmaceutical research and manufacturers of America

Biologicals, ISSN: 10451056

David Allen; Baffi; James Bausch; Jacob Bongers; Maureen Costello; John Dougherty; Federici; Robert L. Garnick; Sydney Peterson; Ralph Riggins; Sewerin; Jody Tuls

January 1, 1996

Acute hypertension, but not thrombolysis, increases the incidence and severity of hemorrhagic transformation following experimental stroke in rabbits

Experimental Neurology, ISSN: 00144886

Mark P. Bowes; Justin A. Zivin; G. Roger Thomas; Harold Thibodeaux; Susan C. Fagan

January 1, 1996

Hospital protocols and policies that may delay early identification and thrombolytic therapy of acute myocardial infarction patients

Journal of Thrombosis and Thrombolysis, ISSN: 09295305

Costas Lambrew; W.Douglas Weaver; William J. Rogers; Laura J. Bowlby; R. Michael Rubison; William J. French

January 1, 1996

Regulation of integrin function by the urokinase receptor

Science, ISSN: 00368075

Ying Wei; Matvey Lukashev; Daniel I. Simon; Bodary; Steven Rosenberg; Michael V. Doyle; Harold A. Chapman

January 1, 1996

Differential damage to auditory neurons and hair cells by ototoxins and neuroprotection by specific neurotrophins in rat cochlear organotypic cultures

European Journal of Neuroscience, ISSN: 0953816X

Zheng; Gao

January 1, 1996

Hematopoiesis: Wandering progenitor cells

Current Biology, ISSN: 09609822

Lasky

January 1, 1996

The role of an agrin-growth factor interaction in ACh receptor clustering

Molecular and Cellular Neuroscience, ISSN: 10447431

David F. Daggett; Cohen; Donna Stone; Nikolics; Heikki Rauvala; H. Benjamin Peng

January 1, 1996

β1 integrins and osteoclast function: Involvement in collagen recognition and bone resorption

Bone, ISSN: 87563282

Helfrich; Nesbitt; Lakkakorpi; Barnes; Bodary; Shankar; Mason; Mendrick; Väänänen; Horton

January 1, 1996

Slipped capital femoral epiphysis in children treated with growth hormone

Hormone Research, ISSN: 16632826 16632818

Sandra L. Blethen; Amy Chen Rundle

January 1, 1996

Recombinant human growth hormone (GH)-binding protein enhances the growth-promoting activity of human GH in the rat

Endocrinology, ISSN: 00137227

Ross Clark; Deborah L. Mortensen; Carlsson; Steven A. Spencer; McKay; Michael G. Mulkerrin; Moore; Cunningham

January 1, 1996

Control of islet intercellular adhesion molecule-1 expression by interferon-α and hypoxia

Diabetes, ISSN: 00121797

Debasis Chakrabarti; Huang; Joanne T. Beck; Jill Henrich; Nancy McFarland; James; Stewart

January 1, 1996

Effects of 12-week administration of dornase alfa in patients with advanced cystic fibrosis lung disease

Chest, ISSN: 00123692

Karen McCoy; Scott A. Hamilton; Charles A. Johnson

January 1, 1996

Antibody to native human immunodeficiency virus type 1 envelope glycoproteins induced by IIIB and MN recombinant gp120 vaccines

Clinical and Diagnostic Laboratory Immunology, ISSN: 1071412X

Geoffrey Gorse; Gira B. Patel; Frances K. Newman; Robert Belshe; Berman; Timothy Gregory; David Schwartz; Jack Lambert; Mary Lou Clements; Sharon E. Frey; Mark Mulligan; Edward Hook; Thomas Evans; Michael C. Keefer; Raphael Dolin; M. Juliana McElrath; Lawrence Corey; Barney S. Graham; Peter Wright; Matthews; Dani P. Bolognesi; James McNamara; Mary Clare Walker; Patricia Fast

January 1, 1996

Transcytosis of protein through the mammalian cerebral epithelium and endothelium. III. Receptor-mediated transcytosis through the blood-brain barrier of blood-borne transferrin and antibody against the transferrin receptor

Experimental Neurology, ISSN: 00144886

Richard D. Broadwell; Cairns; Phillip M. Friden; Constance Oliver; Juan C. Villegas

January 1, 1996

Sustained release of recombinant human growth hormone from dextran via hydrolysis of an imine bond

Journal of Controlled Release, ISSN: 01683659

John E. Battersby; Ross Clark; William S. Hancock; Estela Puchulu-Campanella; Neill Haggarty; Dick Poll; David Harding

January 1, 1996

Limiting systemic plasminogenolysis reduces the bleeding potential for tissue-type plasminogen activators but not for streptokinase

Thrombosis and Haemostasis, ISSN: 03406245

G. Roger Thomas; Harold Thibodeaux; Carol J. Errett; Julie M. Badillo; Daisy T. Wu; Refino; Keyt; William F. Bennett

January 1, 1996

The treatment of systemic lupus erythematosus (SLE) in NZB/W F1 hybrid mice; studies with recombinant murine DNase and with dexamethasone

Clinical and Experimental Immunology, ISSN: 00099104

Macanovic; Sinicropi; Shak; Sharon A. Baughman; Thiru; Peter J. Lachmann

January 1, 1996

Experimental cerebral venous thrombosis: Evaluation using magnetic resonance imaging

Journal of Cerebral Blood Flow and Metabolism, ISSN: 0271678X

Joachim Röther; Kim Waggie; Nicholas Van Bruggen; De Crespigny; Michael Moseley

January 1, 1996

Control of islet intercellular adhesion molecule-1 expression by interferon-α and hypoxia

Diabetes, ISSN: 00121797

Debasis Chakrabarti; Huang; Joanne Beck; Jill Henrich; Nancy McFarland; James; Stewart

January 1, 1996

Circulating thrombopoietin concentrations in thrombocytopenic patients, including cancer patients following chemotherapy, with or without peripheral blood progenitor cell transplantation

British Journal of Haematology, ISSN: 00071048

Meng; Thomas G. Martin III; Peterson; Shuman; Robert L. Cohen; Wai Lee T. Wong

January 1, 1996

A development and validation process for a disease-specific quality of life instrument

Drug Information Journal, ISSN: 00928615

Terri L. Young; Leonard Kirchdoerfer; Jane T. Osterhaus

January 1, 1996

Multiple factors control the proliferation and differentiation of rat early embryonic (Day 9) neuroepithelial cells

Endocrine, ISSN: 15590100 1355008X

Li; Gao; Mather

January 1, 1996

Real time quantitative PCR

Genome Research, ISSN: 10549803

Christian A. Heid; Junko Stevens; Kenneth J. Livak; P. Mickey Williams

January 1, 1996

Salivary binding antibodies induced by human immunodeficiency virus type 1 recombinant gp120 vaccine

Clinical and Diagnostic Laboratory Immunology, ISSN: 1071412X

Geoffrey Gorse; Ellen Y. Yang; Robert Belshe; Berman

January 1, 1996

Circulating thrombopoietin concentrations in thrombocytopenic patients, including cancer patients following chemotherapy, with or without peripheral blood progenitor cell transplantation

British Journal of Haematology, ISSN: 00071048

Meng; Thomas G. Martin III; Michael L. Peterson; Shuman; Robert L. Cohen; Wai Lee T. Wong

January 1, 1996

A novel method for real time quantitative RT-PCR

Genome Research, ISSN: 10549803

Ursula E.M. Gibson; Christian A. Heid; P. Mickey Williams

January 1, 1996

Dissection of c-Mpl and thrombopoietin function: Studies of knockout mice and receptor signal transduction

Stem Cells, ISSN: 10665099

Austin L. Gurney; Frederic J. De Sauvage

January 1, 1996

Refined chromosomal localization of the human thrombopoietin gene to 3q27-q28 and exclusion as the responsible gene for thrombocytosis in patients with rearrangements of 3q21 and 3q26

Leukemia, ISSN: 08876924

Schnittger; Frederic J. De Sauvage; Le Paslier; Fonatsch

January 1, 1996

Development of a single-shot subunit vaccine for HIV-1. 2. Defining optimal autoboost characteristics to maximize the humoral immune response

Journal of Pharmaceutical Sciences, ISSN: 00223549

Cleland; Barron; Berman; Daugherty; Timothy Gregory; Lim; Vennari; Wrin; Powell

January 1, 1996

Regulatory expectation for data on viral testing and process evaluation for phase I studies and product licensing in the United States, Europe and Japan.

Developments in biological standardization, ISSN: 03015149

Dinowitz; Sernatinger; Wiebe

January 1, 1996

Hematologically important mutations: The autosomal recessive forms of chronic granulomatous disease

Blood Cells, Molecules, and Diseases, ISSN: 10799796

Andrew R. Cross; John T. Curnutte; Heyworth

January 1, 1996

Vascular endothelial growth factor

European Journal of Cancer, ISSN: 09598049

Napoleone Ferrara

January 1, 1996

Experience with viral contamination in cell culture.

Developments in biological standardization, ISSN: 03015149

Robert L. Garnick

January 1, 1996

The cation independent mannose-6-phosphate receptor/ insulin-like growth factor ii receptor (cimpr) modulates the subcellular distribution of the urokinase receptor (upar)

Fibrinolysis, ISSN: 02689499

Nykjaer; Petersen; Hager; Nielsen; Rasmussen; Vilhardt; Shuman; Robert L. Cohen; Stuart Kornfeld; Erik Ilsø Christensen; Gliemann

January 1, 1996

Stability and characterization of recombinant human relaxin.

Chinese Journal of Pharmaceutical Biotechnology, ISSN: 10780467

Tue H. Nguyen; Steven J. Shire

January 1, 1996

Apo-3, a new member of the tumor necrosis factor receptor family, contains a death domain and activates apoptosis and NF-κB

Current Biology, ISSN: 09609822

Scot A. Marsters; James P. Sheridan; Christopher J. Donahue; Pitti; Christa Gray; Goddard; Kenneth D. Bauer; Avi Ashkenazi

January 1, 1996

Activation of apoptosis by Apo-2 ligand is independent of FADD but blocked by CrmA

Current Biology, ISSN: 09609822

Scot A. Marsters; Pitti; Christopher J. Donahue; Siegfried Ruppert; Kenneth D. Bauer; Avi Ashkenazi

January 1, 1996

The secondary structure and aggregation of lyophilized tetanus toxoid

Journal of Pharmaceutical Sciences, ISSN: 00223549

Henry R. Costantino; Schwendeman; Kai Griebenow; Klibanov; Langer

January 1, 1996

Gene transfer and amplification in CHO cells: Efficient methods for maximizing specific productivity and assessment of genetic consequences

Annals of the New York Academy of Sciences, ISSN: 00778923

Florian M. Wurm; Johnson; Thomas Ryll; Christiane Köhne; Harry Scherthan; Frank Glaab; Yolanda S. Lie; Christos J. Petropoulos; W. Robert Arathoon

January 1, 1996

Activin Signaling through Activin Receptor Type II Causes the Cachexia-Like Symptoms in Inhibin-Deficient Mice

Molecular Endocrinology, ISSN: 08888809

Katherine A. Coerver; Woodruff; Finegold; Mather; Allan Bradley; Matzuk

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