Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13151 - 13200 OF 15397 RESULTS

Reevaluation of the roles of protein S and gas6 as ligands for the receptor tyrosine kinase Rse/Tyro 3
Cell, ISSN: 00928674
Godowski; Melanie R Mark; Jian Chen; Michael D Sadick; Helga Raab; R. Glenn Hammonds
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Missing link in angiogenesis
Nature, ISSN: 00280836
Napoleone Ferrara
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Recombinant human growth hormone in infants and young children with chronic renal insufficiency
Pediatric Nephrology, ISSN: 0931041X 1432198X
Richard N. Fine; Kenneth M. Attie; Joyce Kuntze; Douglas F. Brown; Edward C. Kohaut
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A Comparison of neutron diffraction and molecular dynamics structures: Hydroxyl group and water molecule orientations in trypsin
Journal of Molecular Biology, ISSN: 00222836
Robert S. McDowell; Anthony A. Kossiakoff
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Cytochrome b-245 of the neutrophil superoxide-generating system contains two nonidentical hemes: Potentiometric studies of a mutant form of gp91phox
Journal of Biological Chemistry, ISSN: 00219258
Andrew R. Cross; Julie Rae; John T. Curnutte
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Allergen-induced histamine release in rat mast cells transfected with the α subunits of FcεRI
Journal of Immunological Methods, ISSN: 00221759
John Lowe; Paula Jardieu; Kimmie VanGorp; David T.W. Fei
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Growth hormone improves cardiac performance in experimental heart failure
Circulation, ISSN: 00097322
Renhui Yang; Bunting; Nancy Gillett; Ross Clark; Hongkui Jin
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Stimulation of myofibrillar protein synthesis in hindlimb suspended rats by resistance exercise and growth hormone
Life Sciences, ISSN: 00243205
Jon K. Linderman; Justen B. Whittall; Kristin L. Gosselink; Tommy J. Wang; Mukku; Frank W. Booth; Richard E. Grindeland
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Stereochemistry of the benzodiazepine based Ras farnesyltransferase inhibitors
Bioorganic and Medicinal Chemistry Letters, ISSN: 0960894X
Thomas E. Rawson; Todd C. Somers; James C. Marsters Jr.; Dairian T. Wan; Mark E. Reynolds; Burdick
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Interferon γ signals via a high-affinity multisubunit receptor complex that contains two types of polypeptide chain
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Scot A. Marsters; Diane Pennica; Bach; Schreiber; Avi Ashkenazi
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Processing of C-terminal lysine and arginine residues of proteins isolated from mammalian cell culture
Journal of Chromatography A, ISSN: 00219673
Reed J. Harris
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Isolation of cDNA clones encoding the mouse protein V-1
Gene, ISSN: 03781119
Diane Pennica; Kenneth J. Shaw; Shiuh-Ming Luoh; William I. Wood
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Identification of functionally important helical faces in transmembrane segments by scanning mutagenesis
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Geoffrey F. Lee; David P. Dutton; Gerald L. Hazelbauer
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Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Austin L. Gurney; Suzan C. Wong; William J. Henzel; Frederic J. De Sauvage
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Cloning and expression of a second photoreceptor-specific membrane retina guanylyl cyclase (RetGC), RetGC-2
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
David G Lowe; Alexander M. Dizhoor; Kathleen Liu; Qimin Gu; Maribeth Spencer; Richard Laura; Lucy Lu; James B. Hurley
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Distinct regions of c-Mpl cytoplasmic domain are coupled to the JAK-STAT signal transduction pathway and Shc phosphorylation
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Austin L. Gurney; Susan C. Wong; William J. Henzel; Frederic J. De Sauvage
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Recovery of disturbed endothelium-dependent flow in the collateral-perfused rabbit ischemic hindlimb after administration of vascular endothelial growth factor
Circulation, ISSN: 00097322
Christophe Bauters; Takayuki Asahara; Lu P. Zheng; Satoshi Takeshita; Bunting; Napoleone Ferrara; James F. Symes; Jeffrey M. Isner
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Local delivery of vascular endothelial growth factor accelerates reendothelialization and attenuates intimai hyperplasia in balloon-injured rat carotid artery
Circulation, ISSN: 00097322
Takayuki Asahara; Christophe Bauters; Christopher Pastore; Marianne Kearney; Susan T. Rossow; Bunting; Napoleone Ferrara; James F. Symes; Jeffrey M. Isner
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Reduced recruitment of inflammatory cells in a contact hypersensitivity response in P-selectin-deficient mice
Journal of Experimental Medicine, ISSN: 15409538 00221007
Meera Subramaniam; Simin Saffaripour; Susan R. Watson; Tanya N. Mayadas; Richard O. Hynes; Denisa D. Wagner
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Theiler’s virus infection of 129Sv mice that lack the interferon α/ß or interferon γ receptors
Journal of Experimental Medicine, ISSN: 15409538 00221007
Laurence Fiette; Christine Aubert; Ulrike Müller; Sui Huang; Michel Aguet; Michel Brahic; Jean-François Bureau
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Ecotin is a potent inhibitor of the contact system proteases factor XIIa and plasma kallikrein
FEBS Letters, ISSN: 00145793
Jana S. Ulmer; Robert N. Lindquist; Dennis; Lazarus
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Protective roles of cytokines against radiation: Induction of mitochondrial MnSOD
Biochimica et Biophysica Acta - Molecular Basis of Disease, ISSN: 09254439
Grace H.W. Wong
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Regulation of cell signaling by the cytoplasmic domains of the heat-stable enterotoxin receptor: Identification of autoinhibitory and activating motifs
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Xiaowen L. Rudner; Kathryn K. Mandal; Frederic J. De Sauvage; L. Allen Kindman; June S. Almenoff
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A mutant of melanoma growth stimulating activity does not activate neutrophils but blocks erythrocyte invasion by malaria
Journal of Biological Chemistry, ISSN: 00219258
Joseph Hesselgesser; Chitnis; Miller; Yansura; Laura C. Simmons; Wayne J. Fairbrother; Claire Kotts; Wirth; Beth Gillece-Castro; Richard Horuk
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Activation and Characterization of Procarboxypeptidase B from Human Plasma
Biochemistry, ISSN: 15204995 00062960
Tan; Dan L. Eaton
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Early interleukin 12 production by macrophages in response to mycobacterial infection depends on interferon γ and tumor necrosis factor α
Journal of Experimental Medicine, ISSN: 15409538 00221007
Inge E. A. Flesch; Jürgen H. Hess; Sui Huang; Michel Aguet; Joachim Rothe; Horst Bluethmann; Stefan H. E. Kaufmann
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The stimulatory effects of interleukin (IL)-12 on hematopoiesis are antagonized by IL-12-induced interferon γ in vivo
Journal of Experimental Medicine, ISSN: 15409538 00221007
Vicki M. Eng; Bruce D. Car; Bruno Schnyder; Meike Lorenz; Serena Lugli; Michel Aguet; Timothy D. Anderson; Bernhard Ryffel; Valerie F. J. Quesniaux
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The retinoblastoma-susceptibility gene product binds directly to the human TATA-binding protein-associated factor TAFII250
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Zhaohui Shao; Siegfried Ruppert; Paul D. Robbins
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A variant X-linked chronic granulomatous disease patient (X91+) with partially functional cytochrome b
Journal of Biological Chemistry, ISSN: 00219258
Andrew R. Cross; Heyworth; Julie Rae; John T. Curnutte
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Use of multifactorial analysis to develop aqueous two-phase systems for isolation of non-native IGF-I
Bioseparation, ISSN: 0923179X
Hart; John R. Ogez; Stuart E. Builder
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The duffy antigen/receptor for chemoklnes (DARC) is expressed in endothelial cells of duffy negative individuals who lack the erythrocyte receptor
Journal of Experimental Medicine, ISSN: 15409538 00221007
Stephen C. Peiper; Zi-Xuan Wang; Kuldeep Neote; Alvin W. Martin; Henry J. Showell; Maryrose J. Conklyn; Kevin Ogborne; Hadley; Zhao-Hai Lu; Joseph Hesselgesser; Richard Horuk
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Insulin-like growth factor-1 and growth hormone (GH) have distinct and overlapping anabolic effects in GH-deficient rats
Endocrine, ISSN: 0969711X 15590100
Ross Clark; Deborah L. Mortensen; Carlsson
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Proton NMR Assignments and Solution Conformation of RANTES, a Chemokine of the C-C Type
Biochemistry, ISSN: 15204995 00062960
Nicholas J. Skelton; Fernando Aspiras; John R. Ogez; J. Schall Thomas
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The cytosolic activating factors P47phox and p67phox have distinct roles in the regulation of electron flow in NADPH oxidase
Journal of Biological Chemistry, ISSN: 00219258
Andrew R. Cross; John T. Curnutte
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Molecular cloning of a ligand for the EPH-related receptor protein-tyrosine kinase Htk
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Brian D. Bennett; Francis C. Zeigler; Qimin Gu; Brian M. Fendly; Goddard; Nancy Gillett; William Matthews
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Mice from a genetically resistant background lacking the interferon γ receptor are susceptible to infection with leishmania major but mount a polarized T helper cell 1-type CD4+ T cell response
Journal of Experimental Medicine, ISSN: 15409538 00221007
Kristin Swihart; Ulrich Fruth; Nathalie Messmer; Katharina Hug; Reza Behin; Sui Huang; Giuseppe Del Giudice; Michel Aguet; Jacques A. Louis
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Axon-induced mitogenesis of human Schwann cells involves heregulin and p185erbB2
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Thomas K. Morrissey; Allan D. O. Levi; Andrew Nuijens; Mark X. Sliwkowski; Richard P. Bunge
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The use of laser diffraction for the evaluation of the aerosol clouds generated by medical nebulizers
International Journal of Pharmaceutics, ISSN: 03785173
Clark
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Development of anti-p185HER2 immunoliposomes for cancer therapy
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Park; Hong; Paul J. Carter; Asgari; Guo; Gilbert-Andre Keller; Wirth; Shalaby; Claire Kotts; William I. Wood; Papahadjopoulos; Benz
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Characterization of the hormone binding site of natriuretic peptide receptor-C
FEBS Letters, ISSN: 00145793
Alfred M Engel; David G Lowe
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Development of a Humanized Disulfide-stabilized Anti-p185HER2 Fv-β-Lactamase Fusion Protein for Activation of a Cephalosporin Doxorubicin Prodrug
Cancer Research, ISSN: 15387445 00085472
Maria L. Rodrigues; Presta; Claire Kotts; Wirth; Joyce Mordenti; Gary Osaka; Wai Lee T. Wong; Andrew Nuijens; Brent Blackburn; Paul J. Carter
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Genomic structure, chromosomal localization, and conserved alternative splice forms of thrombopoietin
Blood, ISSN: 00064971
Austin L. Gurney; Wun-Jing Kuang; Xie; Malloy; Dan L. Eaton; Frederic J. De Sauvage
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Membrane glycoprotein PC-1 and insulin resistance in non-insulin-dependent diabetes mellitus
Nature, ISSN: 00280836
Betty A. Maddux; Paolo Sbraccia; Shinobu Kumakura; Shlomo Sasson; Jack Youngren; Alexander Fisher; Steven A. Spencer; Andrew Grupe; William J. Henzel; Stewart; Gerald M. Reaven; Ira D. Goldfine
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Bispecific HER2 × CD3 Antibodies Enhance T-Cell Cytotoxicity in Vitro and Localize to HER2-Overexpressing Xenografts in Nude Mice
Clinical Immunology and Immunopathology, ISSN: 00901229
Shalaby; Paul J. Carter; Daniel A. Maneval; Giltinan; Claire Kotts
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Apoptosis in CHO cell batch cultures: examination by flow cytometry
Cytotechnology, ISSN: 09209069 15730778
Alison Moore; Christopher J. Donahue; Jeff Hooley; Diana L. Stocks; Kenneth D. Bauer; Mather
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Monoclonal antibodies specific for murine p55 and p75 tumor necrosis factor receptors: Identification of a novel in vivo role for p75
Journal of Experimental Medicine, ISSN: 15409538 00221007
Kathleen C. Sheehan; J. Keith Pinckard; Cora D. Arthur; Louis P. Dehner; David V. Goeddel; Schreiber
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Effects of growth hormone in rats with postinfarction left ventricular dysfunction
Cardiovascular Drugs and Therapy, ISSN: 09203206 15737241
Renhui Yang; Bunting; Nancy Gillett; Ross Clark; Hongkui Jin
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Expression cloning of cardiotrophin 1, a cytokine that induces cardiac myocyte hypertrophy
Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424
Diane Pennica; King; Kenneth J. Shaw; Luis; Janette Rullamas; Shiuh-Ming Luoh; Darbonne; Deborah S. Knutzon; Randy Yen; Kenneth R. Chien; Baker; William I. Wood
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Nerve growth factor levels in cultured human skin cells: effect of gestation and viral transformation
Neuroscience Letters, ISSN: 03043940
Anand; Foley; Navsaria; Sinicropi; Williams-Chestnut; Leigh
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Mesencephalic dopaminergic neurons protected by gdnf from axotomy-induced degeneration in the adult brain
Nature, ISSN: 00280836
Klaus D. Beck; Janet Valverde; Alexi; Kris Poulsen; Moffat; Richard L. Vandlen; Rosenthal; Franz Hefti
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