Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

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January 1, 1995

The Timing of Sexual Maturation in a Group of US White Youths

Journal of Pediatric Endocrinology and Metabolism, ISSN: 21910251 0334018X

Roche; Wellens; Kenneth M. Attie; Siervogel

January 1, 1995

Development of a single administration subunit vaccine for HIV-1

Proceedings of the Controlled Release Society, ISSN: 10220178

Cleland; Powell; Lim; Barron; Berman; Nunberg; Eastman; Wrin; Vennari; Murthy; Kensil; Jia-Yan Wu

January 1, 1995

Intracellular tyrosine residues of the human growth hormone receptor are not required for the signaling of proliferation or Jak-STAT activation

Journal of Biological Chemistry, ISSN: 00219258

Wang; Wong; William I. Wood

January 1, 1995

Leukemia inhibitory factor and tumor necrosis factor induce manganese superoxide dismutase and protect rabbit hearts from reperfusion injury

Journal of Molecular and Cellular Cardiology, ISSN: 00222828

Sally K. Nelson; Grace H.W. Wong; Joe M. McCord

January 1, 1995

Stability and activity of alteplase with injectable drugs commonly used in cardiac therapy

American Journal of Health-System Pharmacy, ISSN: 10792082

Lam; Carole A. Ward; Du Mee

January 1, 1995

Heterodimeric neurotrophins induce phosphorylation of Trk receptors and promote neuronal differentiation in PC12 cells

Journal of Biological Chemistry, ISSN: 00219258

Treanor; Charles H. Schmelzer; Beat Knüsel; Winslow; David L. Shelton; Franz Hefti; Nikolics; Louis E. Burton

January 1, 1995

Identification of heavy chain residues in a humanized anti-CD3 antibody important for efficient antigen binding and T cell activation

Journal of Immunology, ISSN: 00221767

Zhu; Paul J. Carter

January 1, 1995

Inhibition of insulin receptor phosphorylation by PC-1 is not mediated by the hydrolysis of adenosine triphosphate or the generation of adenosine

Journal of Biological Chemistry, ISSN: 00219258

Andrew Grupe; Alleman; Ira D. Goldfine; Michael D Sadick; Stewart

January 1, 1995

Laboratory empiricism, clinical design, and social value. The rough road toward vaccine development.

Chinese Journal of Pharmaceutical Biotechnology, ISSN: 10780467

Francis

January 1, 1995

Characterization of recombinant human growth hormone - PLGA formulations in animals

Proceedings of the Controlled Release Society, ISSN: 10220178

Cleland; Duenas; Daugherty; Marian; Yang; Wilson; Shahzamani; Chu; Mukku; Maa; Chung C. Hsu; Andrew J.S. Jones

January 1, 1995

An immunoglobulin-like domain determines the specificity of neurotrophin receptors

EMBO Journal, ISSN: 02614189

Urfer; Tsoulfas; O'Connell; David L. Shelton; Parada; Presta

January 1, 1995

The limbic system-associated membrane protein is an Ig superfamily member that mediates selective neuronal growth and axon targeting

Neuron, ISSN: 08966273

Aurea F. Pimenta; Victoria Zhukareva; Mary F. Barbe; Blesilda S. Reinoso; Christopher Grimley; William J. Henzel; Itzhak Fischer; Pat Levitt

January 1, 1995

Pulmonary o2 toxicity: Role of endogenous tumor necrosis factor

Experimental Lung Research, ISSN: 01902148

Min-Fu Tsan; Julie E. White; Phyllis B. Michelsen; Grace H.W. Wong

January 1, 1995

Anti-lge monoclonal antibodies that inhibit allergen-specific histamine release

International Archives of Allergy and Immunology, ISSN: 14230097 10182438

Robert L. Shields; Winifred R. Werther; Kimberly Zioncheck; O'Connell; Toni Klassen; Brian M. Fendly; Presta; Paula Jardieu

January 1, 1995

Immobilized animal cell bioreactors.

Bioprocess technology, ISSN: 08887470

Croughan; Chiou; Daniel I. C. Wang

January 1, 1995

Determination of the solution structure of apo calbindin D9k by NMR spectroscopy

Journal of Molecular Biology, ISSN: 00222836

Nicholas J. Skelton; Johan Kördel; Walter J. Chazin

January 1, 1995

Protection against endotoxic shock by bactericidal/permeability- increasing protein in rats

Journal of Clinical Investigation, ISSN: 00219738

Hongkui Jin; Renhui Yang; Scot A. Marsters; Avi Ashkenazi; Bunting; Marra; Scott; Baker

January 1, 1995

Hypertension in pregnancy: Changes in activin a maternal serum concentration

Placenta, ISSN: 01434004

Petraglia; Aguzzoli; Gallinelli; Florio; Zonca; Benedetto; Woodruff

January 1, 1995

The sialomucin CD34 is expressed on hematopoietic cells and blood vessels during murine development

Blood, ISSN: 00064971

Paul Young; Baumhueter; Lasky

January 1, 1995

Natriuretic peptide receptor-B (guanylyl cyclase-B) mediates C-type natriuretic peptide relaxation of precontracted rat aorta

Journal of Biological Chemistry, ISSN: 00219258

Drewett; Brian M. Fendly; Garbers; David G Lowe

January 1, 1995

Adaptation of the growth hormone and insulin-like growth factor-I axis to chronic and severe calorie or protein malnutrition

Journal of Clinical Investigation, ISSN: 00219738

Oster; Fielder; Nancy Levin; Cronin

January 1, 1995

Quantitative approaches to utilizing mutational analysis and disulfide crosslinking for modeling a transmembrane domain

Protein Science, ISSN: 1469896X 09618368

Geoffrey F. Lee; Gerald L. Hazelbauer

January 1, 1995

Matrix-assisted laser desorption/ionization mass spectrometry (MALDI-MS)

Current Opinion in Structural Biology, ISSN: 0959440X

Stults

January 1, 1995

Leukemia inhibitory factor and tumor necrosis factor induce manganese superoxide dismutase and protect rabbit hearts from reperfusion injury

Journal of Molecular and Cellular Cardiology, ISSN: 00222828

Sally K. Nelson; Grace H.W. Wong; Joe M. McCord

January 1, 1995

Hypoxic Regulation of Vascular Endothelial Growth Factor in Retinal Cells

Archives of Ophthalmology, ISSN: 15383601 00039950

Lloyd Paul Aiello; Jill M. Northrup; Keyt; Hitoshi Takagi; Mami A. Iwamoto

January 1, 1995

Identification of amino acids in the CD11a I-domain important for binding of the leukocyte function-associated antigen-1 (LFA-1) to intercellular adhesion molecule-1 (ICAM-1)

Journal of Biological Chemistry, ISSN: 00219258

Caroline P. Edwards; Mark Champe; Gonzalez; Wessinger; Steven A. Spencer; Presta; Berman; Bodary

January 1, 1995

A simulation study of estimators for rates of change in longitudinal studies with attrition

Statistics in Medicine, ISSN: 10970258 02776715

Wang-Clow; Mary Lange; Laird; James H. Ware

January 1, 1995

Tissue- and age-specific expression patterns of alternatively spliced Agrin mRNA transcripts in embryonic rat suggest novel developmental roles

Journal of Neuroscience, ISSN: 02706474

Donna Stone; Nikolics

January 1, 1995

Correlation of solute flux across Caco-2 monolayers and colonic tissue in vitro

S.T.P. Pharma Sciences, ISSN: 11571489

Rubas; Villagran; Cromwell; McLeod; Wassenberg; Mrsny

January 1, 1995

Characterization of the MN gp120 HIV-1 Vaccine: Antigen Binding to Alum

Pharmaceutical Research, ISSN: 1573904X 07248741

Weissburg; Berman; Cleland; Eastman; Francis Farina; Frie; Lim; Joyce Mordenti; Peterson; Yim; Powell

January 1, 1995

Development of a new in vitro release method for microencapsulated proteins

Proceedings of the Controlled Release Society, ISSN: 10220178

Duenas; Yang; Andrew J.S. Jones; Cleland

January 1, 1995

Hyperadrenocorticism and food restriction-induced life extension in the rat: Evidence for divergent regulation of pituitary proopiomelanocortin RNA and adrenocorticotropic hormone biosynthesis

Journals of Gerontology - Series A Biological Sciences and Medical Sciences, ISSN: 1758535X 10795006

Eun-Soo Han; Nancy Levin; Nomsa Bengani; James L. Roberts; Yongman Sun; Katarzyna Karelus; James F. Nelson

January 1, 1995

Stability of Protein Formulations: Investigation of Surfactant Effects by a Novel EPR Spectroscopic Technique

Pharmaceutical Research, ISSN: 1573904X 07248741

Narendra B. Bam; Theodore W. Randolph; Cleland

January 1, 1995

In vitro release of bioactive recombinant human interferon-γ from PLGA microspheres

Proceedings of the Controlled Release Society, ISSN: 10220178

Cleland; Yang

January 1, 1995

Development of stable protein formulations for microencapsulation in biodegradable polymers

Proceedings of the Controlled Release Society, ISSN: 10220178

Cleland; Andrew J.S. Jones

January 1, 1995

A rapid method for detection of mycoplasmas in mammalian cell cultures and comparison with other routine techniques

Enzyme and Microbial Technology, ISSN: 01410229

Ulrich Valley; Klaus Scharfenberg; Katja Müller; Thomas Ryll; Roland Wagner

January 1, 1995

Regulation of the expression of IL-8 receptor A/B by IL-8: Possible functions of each receptor

Journal of Immunology, ISSN: 00221767

Anan Chuntharapai; K.Jin Kim

January 1, 1995

A Humanized, Bispecific Immunoadhesin-Antibody that Retargets CD3+ Effectors to Kill HIV-1-Infected Cells

Journal of Hematotherapy, ISSN: none 15258165

Steven M. Chamow; Zhang; Xiang Y. Tan; Mhatre; Scot A. Marsters; Peers; Randal A. Byrn; Avi Ashkenazi; Junghans

January 1, 1995

Effects of lovastatin on trafficking of cystic fibrosis transmembrane conductance regulator in human tracheal epithelium

Journal of Biological Chemistry, ISSN: 00219258

Shen; Widdicombe; Mrsny

January 1, 1995

Transport of Biologically Active Interferon-gamma Across Human Skin in Vitro

Pharmaceutical Research, ISSN: 1573904X 07248741

Sarah M. Short; Rubas; Paasch; Randall J. ny

January 1, 1995

Potent and selective Kunitz domain inhibitors of plasma kallikrein designed by phage display

Journal of Biological Chemistry, ISSN: 00219258

Dennis; Herzka; Lazarus

January 1, 1995

Interferon expression in the pancreases of patients with type I diabetes

Diabetes, ISSN: 00121797

Huang; Jean Yuan; Goddard; Foulis; James; Lernmark; Pujol- Borrell; Rabinovitch; Somoza; Stewart

January 1, 1995

Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons

Neuron, ISSN: 08966273

Klaus D. Beck; Powell-Braxton; Hans R. Widmer; Janet Valverde; Franz Hefti

January 1, 1995

The public's health unprotected: Reversing a decade of underutilization of hepatitis B vaccine

JAMA - Journal of the American Medical Association, ISSN: 00987484

Francis

January 1, 1995

Linear Free Energy Analysis of Hydrogen Bonding in Proteins

Journal of the American Chemical Society, ISSN: 15205126 00027863

Jon S. Thorson; Eli Chapman; Elizabeth C. Murphy; Peter G. Schultz; J. Kevin Judice

January 1, 1995

Co‐expression of urokinase, urokinase receptor and PAI‐1 is necessary for optimum invasiveness of cultured lung cancer cells

International Journal of Cancer, ISSN: 10970215 00207136

Liu; Shuman; Robert L. Cohen

January 1, 1995

Aerosolized recombinant human DNase I for the treatment of cystic fibrosis

Chest, ISSN: 00123692

Shak

January 1, 1995

Mouse models of IGF-I deficiency generated by gene targeting.

Receptor, ISSN: 10528040

Warburton; Powell-Braxton

January 1, 1995

CD8+ and CD45RA+ human peripheral blood lymphocytes are potent sources of macrophage inflammatory protein 1α, interleukin‐8 and RANTES

European Journal of Immunology, ISSN: 15214141 00142980

Kevin Conlon; Andrew Lloyd; Utpala Chattopadhyay; Nicholas Lukacs; Stephen Kunkel; Thomas J. Schall; Dennis Taub; Chikao Morimoto; Jennifer Osborne; Joost J. Oppenheim; Howard Young; David J. Kelvin; Ortaldo

January 1, 1995

Lack of increased risk for extracranial, nonleukemic neoplasms in recipients of recombinant deoxyribonucleic acid growth hormone

Journal of Clinical Endocrinology and Metabolism, ISSN: 19457197 0021972X

Gordon A. Tuffli; Ann J. Johanson; Amy Chen Rundle; David B. Allen

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