Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13351 - 13400 OF 15397 RESULTS

January 1, 1995

The biological effects of endogenous nerve growth factor on adult sensory neurons revealed by a trka-igg fusion molecule

Nature Medicine, ISSN: 1546170X 10788956

McMahon; David L. H. Bennett; John V. Priestley; David L. Shelton

January 1, 1995

Online education program helps teachers teach science

Bio/Technology, ISSN: 0733222X

Geoff Teeter

January 1, 1995

Removal of sialic acid from a glycoprotein in CHO cell culture supernatant by action of an extracellular cho cell sialidase

Bio/Technology, ISSN: 0733222X

Michael J. Gramer; Charles F. Goochee; Valerie Y. Chock; Dave Brousseau; Mary B. Sliwkowski

January 1, 1995

CD40 ligand has potent antiviral activity

Nature Medicine, ISSN: 1546170X 10788956

Janet Ruby; Horst Bluethmann; Michel Aguet; Ian A. Ramshaw

January 1, 1995

A hot spot of binding energy in a hormone-receptor interface

Science, ISSN: 00368075

Clackson; James A. Wells

January 1, 1995

Ligand-induced autoregulation of IFN-γ receptor β chain expression in T helper cell subsets

Science, ISSN: 00368075

Bach; Susanne J. Szabo; Anand S. Dighe; Avi Ashkenazi; Michel Aguet; Kenneth M. Murphy; Schreiber

January 1, 1995

Myocardial infarction and the nondiagnostic ECG: Strategies to meet the challenges

Journal of Emergency Nursing, ISSN: 15272966 00991767

Katherine A. Littrell; Donna Walker; Cindy Worthy

January 1, 1995

A simulation study of estimators for rates of change in longitudinal studies with attrition

Statistics in Medicine, ISSN: 10970258 02776715

Wang-Clow; Mary Lange; Laird; Ware

January 1, 1995

Expression of the genes encoding the rat renal Insulin-Like growth factor-I system

Journal of the American Society of Nephrology, ISSN: 10466673

Ralph Rabkin; Michael Brody; Lucy Lu; Curtis Chan; Allison M. Shaheen; Nancy Gillett

January 1, 1995

Novel inherited mutations and variable expressivity of BRCA1 alleles, including the founder mutation 185delAG in Ashkenazi Jewish families

American Journal of Human Genetics, ISSN: 00029297

Lori S. Friedman; Szabo; Elizabeth A. Ostermeyer; Patrick Dowd; Lesley Butler; Tari Park; Ming K. Lee; Ellen L. Goode; Sarah E. Rowell; Mary-Claire King

December 20, 1994

Subtiligase: A tool for semisynthesis of proteins

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Thomas K. Chang; Jackson; Burnier; James A. Wells

December 20, 1994

Extensive oxidative DNA damage in hepatocytes of transgenic mice with chronic active hepatitis destined to develop hepatocellular carcinoma

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Tory M. Hagen; Shaonan Huang; John T. Curnutte; Patricia Fowler; Violeta Martinez; Carol M. Wehr; Bruce N. Ames; Francis V. Chisari

December 15, 1994

The binding epitopes of neurotrophin-3 to its receptors trkC and gp75 and the design of a multifunctional human neurotrophin

EMBO Journal, ISSN: 02614189

Urfer; Tsoulfas; Soppet; Escandon; Parada; Presta

December 15, 1994

Monoclonal antibodies detect different distribution patterns of IL-8 receptor A and IL-8 receptor B on human peripheral blood leukocytes

Journal of Immunology, ISSN: 00221767

Anan Chuntharapai; James Lee; Hébert; K.Jin Kim

December 9, 1994

Guanylyl cyclase receptors

Journal of Biological Chemistry, ISSN: 00219258

Garbers; David G Lowe

December 9, 1994

Application of capillary high-performance liquid chromatography to biotechnology, with reference to the analysis of recombinant DNA-derived human growth hormone

Journal of Chromatography B: Biomedical Sciences and Applications, ISSN: 03784347

John E. Battersby; Andrew W. Guzzetta; William S. Hancock

December 1, 1994

Entry of naive CD4 T cells into peripheral lymph nodes requires I-selectin

Journal of Experimental Medicine, ISSN: 15409538 00221007

Linda M. Bradley; Susan R. Watson; Susan L. Swain

December 1, 1994

Phase I studies with biologicals

European Journal of Clinical Research, ISSN: 09613692

Froehlich

November 25, 1994

Temperature as a variable in reversed-phase high-performance liquid chromatographic separations of peptide and protein samples. II. Selectivity effects observed in the separation of several peptide and protein mixtures

Journal of Chromatography A, ISSN: 00219673

Chloupek; William S. Hancock; Brian A. Marchylo; Kirkland; Barry E. Boyes; Lloyd R. Snyder

November 25, 1994

Temperature as a variable in reversed-phase high-performance liquid chromatographic separations of peptide and protein samples. I. Optimizing the separation of a growth hormone tryptic digest

Journal of Chromatography A, ISSN: 00219673

William S. Hancock; Chloupek; Kirkland; Lloyd R. Snyder

November 21, 1994

Neurons from mouse embryos with a null mutation in the tumour suppressor gene p53 undergo normal cell death in the absence of neurotrophins

Neuroscience Letters, ISSN: 03043940

Alun M. Davies; Rosenthal

November 16, 1994

HIV-1(MN) recombinant gp120 vaccine serum, which fails to neutralize primary isolates of HIV-1, does not antagonize neutralization by antibodies from infected individuals [2]

AIDS, ISSN: 02699370

Wrin; Nunberg

November 15, 1994

Biologic activities of the murine β-chemokine TCA3

Journal of Immunology, ISSN: 00221767

Yi Luo; Joseph Laning; Shamala Devi; John Mak; Thomas J. Schall; Martin E. Dorf

November 11, 1994

Rupture of the mitochondrial outer membrane impairs porin assembly

Journal of Biological Chemistry, ISSN: 00219258

Mitchell Smith; Shawn Hicks; Kevin Baker; Roy McCauley

November 4, 1994

Mutagenesis identifies amino-terminal residues of nerve growth factor necessary for Trk receptor binding and biological activity

Journal of Biological Chemistry, ISSN: 00219258

Shih; Laramee; Charles H. Schmelzer; Louis E. Burton; Winslow

November 4, 1994

Assessment of the contribution of the cytochrome b moiety of the NADPH oxidase to the transmembrane H+ conductance of leukocytes

Journal of Biological Chemistry, ISSN: 00219258

Arvind Nanda; Robert Romanek; John T. Curnutte; Sergio Grinstein

November 1, 1994

Colorimetric determination of dnase i activity with a DNA-methyl green substrate

Analytical Biochemistry, ISSN: 10960309 00032697

Sinicropi; Baker; Prince; Shiffer; Shak

November 1, 1994

R-Ras induces malignant, but not morphologic, transformation of NIH3T3 cells

Oncogene, ISSN: 09509232

Adrienne D. Cox; Teresa R. Brtva; David G Lowe; Channing J. Der

November 1, 1994

Cell surface P- and E-selectin support shear-dependent rolling of bovine γ/δ T cells

Journal of Immunology, ISSN: 00221767

Mark A. Jutila; Robert F. Bargatze; Sandy Kurk; R. Aaron Warnock; Niloofar Ehsani; Susan R. Watson; Bruce Walcheck

November 1, 1994

A humanized, bispecific immunoadhesin-antibody that retargets CD3+ effectors to kill HIV-1-infected cells

Journal of Immunology, ISSN: 00221767

Steven M. Chamow; Zhang; Xiang Y. Tan; Mhatre; Scot A. Marsters; Peers; Randal A. Byrn; Avi Ashkenazi; Junghans

November 1, 1994

Intramuscular administration of vascular endothelial growth factor induces dose-dependent collateral artery augmentation in a rabbit model of chronic limb ischemia

Circulation, ISSN: 00097322

Satoshi Takeshita; Li-Qun Pu; Lawrence A. Stein; Allan D. Sniderman; Bunting; Napoleone Ferrara; Jeffrey M. Isner; James F. Symes

November 1, 1994

Determination of the Solution Structure of the Peptide Hormone Guanylin: Observation of a Novel Form of Topological Stereoisomerism

Biochemistry, ISSN: 15204995 00062960

Nicholas J. Skelton; Garcia; David V. Goeddel; Quan; Burnier

November 1, 1994

Conformational Changes in the Reversed Phase Liquid Chromatography of Recombinant Human Growth Hormone as a Function of Organic Solvent: The Molten Globule State

Analytical Chemistry, ISSN: 15206882 00032700

Wicar; Michael G. Mulkerrin; Bathory; Khundkar; Karger

November 1, 1994

Exploring the Microtubule-Binding Region of Bovine Microtubule-Associated Protein-2 (MAP-2): CDNA Sequencing, Bacterial Expression, and Site-Directed

Biochemistry, ISSN: 15204995 00062960

Richard L. Coffey; John C. Joly; Brian D. Cain; Daniel L. Purich

October 27, 1994

Processive recombination by wild-type gin and an enhancer-independent mutant. Insight into the mechanisms of recombination selectivity and strand exchange

Journal of Molecular Biology, ISSN: 00222836

Crisona; Kanaar; Gonzalez; Zechiedrich; Klippel; Cozzarelli

October 25, 1994

Role of the 75-kDa tumor necrosis factor receptor: Inhibition of early hematopoiesis

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Frede W. Jacobsen; Mike Rothe; Leiv Rusten; David V. Goeddel; Erlend B. Smeland; Ole P. Veiby; Lars Slørdal; Sten E. W. Jacobsen

October 25, 1994

Suppression of mammalian 5′ splice-site defects by U1 small nuclear RNAs from a distance

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Justus B. Cohen; Jon E. Snow; Spencer; Levinson

October 21, 1994

The binding site on human immunoglobulin E for its high affinity receptor

Journal of Biological Chemistry, ISSN: 00219258

Presta; Robert L. Shields; O'Connell; Steven Lahr; James P. Porter; Cornelia M. Gorman; Paula Jardieu

October 15, 1994

Indications for growth hormone

The Lancet, ISSN: 01406736

Barry M. Sherman

October 15, 1994

Global vascular expression of murine CD34, a sialomucin-like endothelial ligand for L-selectin

Blood, ISSN: 00064971

Baumhueter; Noel Dybdal; Carrie Kyle; Lasky

October 15, 1994

Cellular and molecular characterization of the role of the FLK-2/FLT-3 receptor tyrosine kinase in hematopoietic stem cells

Blood, ISSN: 00064971

Francis C. Zeigler; Brian D. Bennett; Craig T. Jordan; Spencer; Baumhueter; Carroll; Jeff Hooley; Kenneth D. Bauer; William Matthews

October 14, 1994

A designed peptide ligase for total synthesis of ribonuclease A with unnatural catalytic residues

Science, ISSN: 00368075

Jackson; Burnier; Quan; Mark S. Stanley; Jeffrey Tom; James A. Wells

October 1, 1994

Radioimmunotherapy of Human B-Cell Chronic Lymphocytic Leukemia in Nude Mice

Cancer Research, ISSN: 15387445 00085472

Zhu; Tarunendu Ghose; David Hoskin; Christine L. Y. Lee; Spencer H. S. Lee; Molly Mammen

October 1, 1994

Purification and characterization of α-L-fucosidase from Chinese hamster ovary cell culture supernatant

Glycobiology, ISSN: 09596658

Michael J. Gramer; David V. Schaffer; Mary B. Sliwkowski; Charles F. Goochee

September 20, 1994

Peptide liquid crystals: Inverse correlation of kinetic formation and thermodynamic stability in aqueous solution

Pharmaceutical Research, ISSN: 07248741

Powell; Fleitman; Sanders; Si

September 15, 1994

Megestrol acetate in patients with AIDS and cachexia

Annals of Internal Medicine, ISSN: 00034819

Oster; Sheila R. Enders; Steven J. Samuels; Lawrence A. Cone; Thomas M. Hooton; Henry P. Browder; Neil M. Flynn

September 13, 1994

Development of cancer cachexia-like syndrome and adrenal tumors in inhibin-deficient mice

Proceedings of the National Academy of Sciences of the United States of America, ISSN: 00278424

Matzuk; Finegold; Mather; Lynne Krummen; Lu; Allan Bradley

September 9, 1994

Inducible expression and cellular localization of insulin-degrading enzyme in a stably transfected cell line

Journal of Biological Chemistry, ISSN: 00219258

Wen-Liang Kuo; Barry D. Gehm; Marsha Rich Rosner; Wenlu Li; Gilbert-Andre Keller

September 8, 1994

Effect of aerosolized recombinant human dnase on exacerbations of respiratory symptoms and on pulmonary function in patients with cystic fibrosis

New England Journal of Medicine, ISSN: 15334406 00284793

Henry J. Fuchs; David H. Christiansen; Drucy S. Borowitz; Martha L. Nash; Bonnie W. Ramsey; Arnold L. Smith; Edward M. Morris; Beryl J. Rosenstein; Mary Ellen Wohl

September 1, 1994

Incorporation of bromodeoxyuridine in glutathione s-transferase-positive hepatocytes during rat multistage hepatocarcinogenesis

Carcinogenesis, ISSN: 01433334

Dragan; James R. Hully; Crow; Mass; Pitot

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