Scientists / Publications

Publications

Genentech scientists are encouraged to be creative and active members of the scientific community. We are proud of our publication record in Science, Nature, Cell, and other prestigious peer-reviewed journals, where our annual output consistently rivals or surpasses that of the top academic institutions.

DISPLAYING 13501 - 13550 OF 15397 RESULTS

January 1, 1994

Development of effective therapy for Alzheimer's disease based on neurotrophic factors

Neurobiology of Aging, ISSN: 01974580

Franz Hefti

January 1, 1994

Assessment of aerosol delivery systems for recombinant human deoxyribonuclease

S.T.P. Pharma Sciences, ISSN: 11571489

Cipolla; Clark; Chan; Gonda; Steven J. Shire

January 1, 1994

The contribution of open extremity fractures to infection in multiply injured patients

Injury, ISSN: 00201383

Naziri; William G. Cheadle; David H. Livingston; Jorge L. Rodriguez; Karen M. Starko; Hiram C. Polk

January 1, 1994

Kunitz domain inhibitors of tissue factor-Factor VIIa. I. Potent inhibitors selected from libraries by phage display

Journal of Biological Chemistry, ISSN: 00219258

Dennis; Lazarus

January 1, 1994

Kunitz domain inhibitors of tissue factor-Factor VIIa. II. Potent and specific inhibitors by competitive phage selection

Journal of Biological Chemistry, ISSN: 00219258

Dennis; Lazarus

January 1, 1994

Structural elements which govern the resistance of intestinal tissues to compound transport

Materials Research Society Symposium Proceedings, ISSN: 02729172

Rubas; Cronwell; Thomas Gadek; Narindray; Mrsny

January 1, 1994

X‐ray structures of fragments from binding and nonbinding versions of a humanized anti‐CD18 antibody: Structural indications of the key role of VH residues 59 to 65

Proteins: Structure, Function and Bioinformatics, ISSN: 10970134 08873585

Eigenbrot; Gonzalez; Mayeda; Paul J. Carter; Winifred Werther; Hotaling; Judy Fox; Jeremy Kessler

January 1, 1994

Distribution of Inhaled Aerosols in the Respiratory Tract

Journal of Aerosol Medicine: Deposition, Clearance, and Effects in the Lung, ISSN: 15579026 08942684

Sweeney; Ultman

January 1, 1994

Pharmaco-toxicological expert report on recombinant human deoxyribonuclease I (Pulmozyme(TM) ; rhDNase)

Human and Experimental Toxicology, ISSN: 01445952

Green

January 1, 1994

Engineering an interfacial zinc site to increase hormone-receptor affinity

Chemistry and Biology, ISSN: 10745521

Matthews; James A. Wells

January 1, 1994

Phenobarbital Removal Characteristics of Three Brands of Activated Charcoals: A System Analysis Approach

Pharmaceutical Research, ISSN: 1573904X 07248741

Modi; Veng-Pedersen; Dale Eric Wurster; Mary J. Berg; Dorothy D. Schottelius

January 1, 1994

Towards an immunotherapy for p185(HER2) overexpressing tumors

Advances in Experimental Medicine and Biology, ISSN: 00652598

Paul J. Carter; Maria L. Rodrigues; Gail D. Lewis; Figari; Shalaby

January 1, 1994

Administration of an anti-IgE antibody inhibits CD23 expression and IgE production in vivo

Immunology, ISSN: 00192805

Haak-Frendscho; Robbins; Lyon; Robert L. Shields; Jeff Hooley; Schoenhoff; Paula Jardieu

January 1, 1994

The human photoreceptor membrane guanylyl cyclase, RetGC, is present in outer segments and is regulated by calcium and a soluble activator

Neuron, ISSN: 08966273

Alexander M. Dizhoor; David G Lowe; Elena V. Olshevskaya; Richard Laura; James B. Hurley

January 1, 1994

Probing the conformation of protein (bFGF) precipitates by fluorescence spectroscopy

Journal of Pharmaceutical and Biomedical Analysis, ISSN: 07317085

Shahrokh; Eberlein; Y. John Wang

January 1, 1994

Modelling the deposition of inhaled powdered drug aerosols

Journal of Aerosol Science, ISSN: 00218502

Clark; Mike Egan

January 1, 1994

Adhesion Mediated by Intercellular Adhesion Molecule 1 Attenuates the Potency of Antibodies That Block HIV-1 gp160-Dependent Syncytium Formation

AIDS Research and Human Retroviruses, ISSN: 19318405 08892229

Berman; Nakamura

January 1, 1994

Functions of brain-derived neurotrophic factor, insulin-like growth factor-I and basic fibroblast growth factor in the development and maintenance of dopaminergic neurons

Progress in Neurobiology, ISSN: 03010082

Klaus D. Beck

January 1, 1994

Antibiotic overkill of trauma victims?

American Journal of Surgery, ISSN: 00029610

Dimitri Hadjiminas; William G. Cheadle; David A. Spain; Mark A. Wilson; Alicia Short; Karen M. Starko; Betty J. Harris; David H. Livingston; Jorge L. Rodriguez

January 1, 1994

Panel discussion on vaccine development to meet U.S. and international needs. Perspectives on national and global HIV vaccine development: Potential ways to reduce impediments for biopharmaceutical product development

AIDS Research and Human Retroviruses, ISSN: 08892229

John F. Obijeski

January 1, 1994

Assays for recombinant proteins: A problem in non‐linear calibration

Statistics in Medicine, ISSN: 10970258 02776715

Giltinan; Davidian

January 1, 1994

Multiple mechanisms are responsible for altered expression of gap junction genes during oncogenesis in rat liver

Journal of Cell Science, ISSN: 00219533

Mark J. Neveu; James R. Hully; Karlee L. Babcock; Elliot L. Hertzberg; Bruce J. Nicholson; David L. Paul; Pitot

January 1, 1994

A survey of furin substrate specificity using substrate phage display

Protein Science, ISSN: 1469896X 09618368

Matthews; Goodman; Cornelia M. Gorman; James A. Wells

January 1, 1994

In vitro selection from protein and peptide libraries

Trends in Biotechnology, ISSN: 01677799

Clackson; James A. Wells

January 1, 1994

The crystal structure of affinity-matured human growth hormone at 2 Å resolution

Journal of Molecular Biology, ISSN: 00222836

Ultsch; Somers; Anthony A. Kossiakoff; De Vos

January 1, 1994

The interleukin-8-receptor family: From chemokines to malaria

Immunology Today, ISSN: 01675699

Richard Horuk

January 1, 1994

Infection with pseudomonas cepacia in chronic granulomatous disease: Role of nonoxidative killing by neutrophils in host defense

Journal of Infectious Diseases, ISSN: 15376613 00221899

David P. Speert; Mason Bond; Richard C. Woodman; John T. Curnutte

January 1, 1994

Inhibins, activins, their binding proteins and receptors: Interactions underlying paracrine activity in the testis

Molecular and Cellular Endocrinology, ISSN: 03037207

Alison Moore; Lynne Krummen; Mather

January 1, 1994

Identification of succinimide sites in proteins by N‐terminal sequence analysis after alkaline hydroxylamine cleavage

Protein Science, ISSN: 1469896X 09618368

Kwong; Reed J. Harris

January 1, 1994

Issues with Biotechnology Products in Toxicologic Pathology

Toxicologic Pathology, ISSN: 15331601 01926233

Timothy G. Terrell; Green

January 1, 1994

Benzodiazepine peptidomimetic inhibitors of farnesyltransferase

Bioorganic and Medicinal Chemistry, ISSN: 09680896

James C. Marsters Jr.; Robert S. McDowell; Mark E. Reynolds; David A. Oare; Todd C. Somers; Mark S. Stanley; Thomas E. Rawson; Martin Struble; Burdick; Kathryn S. Chan; Charles M. Duarte; Kenneth J. Paris; Jeffrey Tom; Dairian T. Wan; Yingchun Xue; John P. Bumier

January 1, 1994

Pharmacokinetics and Tissue Distribution of Recombinant Human Transforming Growth Factor Beta1 After Topical and Intravenous Administration in Male Rats

Pharmaceutical Research, ISSN: 1573904X 07248741

Zioncheck; Chen; Richardson; Marina Mora-Wor; Catherine Lucas; Lewis; Green; Joyce Mordenti

January 1, 1994

Diketopiperazine formation and N‐terminal degradation in recombinant human growth hormone

International Journal of Peptide and Protein Research, ISSN: 13993011 03678377

John E. Battersby; William S. Hancock; Eleanor Canova-Davis; Oeswein; O'ONNOR

January 1, 1994

Quality of life in patients with limited small-cell carcinoma of the lung receiving chemotherapy with or without radiation therapy, for cancer and leukemia group B

Psychotherapy and Psychosomatics, ISSN: 14230348 00333190

Tim A. Ahles; Peter M. Silberfarb; Amy Chen Rundle; Jimmie C. Holland; Alice B. Kornblith; George P. Canellos; Mark R. Green; Michael C. Perry

January 1, 1994

Localization of inhibin and activin binding sites in the testis during development by in situ ligand binding

Biology of Reproduction, ISSN: 00063363

Lynne Krummen; Alison Moore; Woodruff; Covello; Taylor; Peter K. Working; Mather

January 1, 1994

Interferon Gamma Administration Increases Monocyte HLA-DR Antigen Expression but Not Endogenous Interferon Production

Archives of Surgery, ISSN: 15383644 00040010

David H. Livingston; Patricia A. Loder; Susan M. Kramer; Ursula E.M. Gibson; Hiram C. Polk

January 1, 1994

Characterization of Aerosols of Human Recombinant Deoxyribonuclease I (rhDNase) Generated by Jet Nebulizers

Pharmaceutical Research, ISSN: 1573904X 07248741

Cipolla; Gonda; Steven J. Shire

January 1, 1994

Plasmid integration, amplification and cytogenetics in CHO cells: Questions and comments

Biologicals, ISSN: 10451056

Florian M. Wurm; Christos J. Petropoulos

January 1, 1994

Comparison of the intermediate complexes of human growth hormone bound to the human growth hormone and prolactin receptors

Protein Science, ISSN: 1469896X 09618368

Anthony A. Kossiakoff; Somers; Ultsch; Andow; Yves A. Muller; De Vos

January 1, 1994

Targeting of liposomes to cells expressing CD4 using glycosylphosphatidylinositol-anchored gp120. Influence of liposome composition on intracellular trafficking

Journal of Biological Chemistry, ISSN: 00219258

Schreier; Paul Moran; Caras

January 1, 1994

Immunogenicity and HIV-1 virus neutralization of MN recombinant glycoprotein 120/HIV-1 QS21 vaccine in baboons

AIDS Research and Human Retroviruses, ISSN: 08892229

Powell; Cleland; Eastman; Lim; Newman; Nunberg; Weissburg; Vennari; Wrin; Berman

January 1, 1994

Molecular and biological properties of an interleukin-1 receptor immunoadhesin

Molecular Immunology, ISSN: 01615890

Pitti; Scot A. Marsters; Haak-Frendscho; Gary Osaka; Joyce Mordenti; Steven M. Chamow; Avi Ashkenazi

January 1, 1994

Generation of soluble interleukin-1 receptor from an immunoadhesin by specific cleavage

Molecular Immunology, ISSN: 01615890

Joanne T. Beck; Scot A. Marsters; Reed J. Harris; Paul J. Carter; Avi Ashkenazi; Steven M. Chamow

January 1, 1994

Electron-microscopic and hydrodynamic characterization of recombinant apolipoprotein (a) and its association with LDL

Chemistry and Physics of Lipids, ISSN: 00093084

Martin L. Phillips; Audra V. Lembertas; Verne N. Schumaker; Lawn; Steven J. Shire; Zioncheck

January 1, 1994

Agonist selectivity determinants in somatostatin receptor subtypes I and II

Journal of Biological Chemistry, ISSN: 00219258

V. Danial Fitzpatrick; Richard L. Vandlen

January 1, 1994

Effect of short-term infusion of recombinant human relaxin on blood pressure in the late-pregnant rhesus macaque (Macaca mulatta)

Obstetrics and Gynecology, ISSN: 1873233X 00297844

Mari S. Golub; Peter K. Working; Jeffrey R. Cragun; Robert A. Cannon; Green

January 1, 1994

Artificial bone graft formulation for rhTGF-β1

Proceedings of the Controlled Release Society, ISSN: 10760458

Tue H. Nguyen; Cromwell; Rita Wong; L. Steven Beck; Plouhar; Ongpipattanakul

January 1, 1994

A carboxylesterase from the parasitic nematode Ascaris suum homologous to the intestinal-specific ges-1 esterase of Caenorhabditis elegans

Comparative Biochemistry and Physiology - B Biochemistry and Molecular Biology, ISSN: 03050491

Marie Azzaria; William J. Henzel; James D. McGhee

January 1, 1994

Therapeutic angiogenesis. A single intraarterial bolus of vascular endothelial growth factor augments revascularization in a rabbit ischemic hind limb model

Journal of Clinical Investigation, ISSN: 00219738

Satoshi Takeshita; Lu P. Zheng; Edi Brogi; Marianne Kearney; Li-Qun Pu; Bunting; Napoleone Ferrara; James F. Symes; Jeffrey M. Isner

January 1, 1994

In vivo response of hepatocytes to growth factors requires an initial priming stimulus

Hepatology, ISSN: 15273350 02709139

Eric M. Webber; Godowski; Nelson Fausto

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